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  1. Article: Artificial intelligence is set to transform mental health services.

    Pandi-Perumal, Seithikurippu R / Narasimhan, Meera / Seeman, Mary V / Jahrami, Haitham

    CNS spectrums

    2023  , Page(s) 1–3

    Abstract: The current development in the field of artificial intelligence and its applications has advantages and disadvantages in the digital age that we now live in. The state of the use of AI for mental health has to be assessed by stakeholders, which includes ... ...

    Abstract The current development in the field of artificial intelligence and its applications has advantages and disadvantages in the digital age that we now live in. The state of the use of AI for mental health has to be assessed by stakeholders, which includes all of us. We must comprehend the trends, gaps, opportunities, challenges, and shortcomings of this new technology. As the field evolves, rules, regulatory frameworks, guidelines, standards, and policies will develop and will progressively scale upwards. To advance the field, mental health professionals must be prepared to meet obstacles and seize possibilities presented by creative and disruptive technologies like AI. Therefore, a collaborative strategy must include multi-stakeholder participation in basic, translational, and clinical aspects of AI. Mental health practitioners need to be ready to face challenges and embrace and harness the power of innovative and disruptive technology such as AI that could offer to move the field forward.
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2008418-3
    ISSN 2165-6509 ; 1092-8529
    ISSN (online) 2165-6509
    ISSN 1092-8529
    DOI 10.1017/S1092852923002456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Depression: A focus on challenges, clinical controversies and collaborative care.

    Narasimhan, Meera

    Asian journal of psychiatry

    2010  Volume 3, Issue 3, Page(s) 95

    Language English
    Publishing date 2010-09
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2010.08.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Sleep and psychosomatic medicine

    Pandi-Perumal, S. R / Narasimhan, Meera / Kramer, Milton

    2016  

    Author's details [edited by] S. R. Pandi-Perumal, Meera Narasimhan, Milton Kramer
    MeSH term(s) Sleep Wake Disorders/psychology ; Psychophysiologic Disorders ; Sleep Wake Disorders/etiology
    Language English
    Size xvi, 340 pages :, illustrations ;, 27 cm
    Edition Second edition.
    Document type Book
    ISBN 9781498737289 ; 1498737285
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Article: Knowledge-Infused Abstractive Summarization of Clinical Diagnostic Interviews: Framework Development Study.

    Manas, Gaur / Aribandi, Vamsi / Kursuncu, Ugur / Alambo, Amanuel / Shalin, Valerie L / Thirunarayan, Krishnaprasad / Beich, Jonathan / Narasimhan, Meera / Sheth, Amit

    JMIR mental health

    2021  Volume 8, Issue 5, Page(s) e20865

    Abstract: Background: In clinical diagnostic interviews, mental health professionals (MHPs) implement a care practice that involves asking open questions (eg, "What do you want from your life?" "What have you tried before to bring change in your life?") while ... ...

    Abstract Background: In clinical diagnostic interviews, mental health professionals (MHPs) implement a care practice that involves asking open questions (eg, "What do you want from your life?" "What have you tried before to bring change in your life?") while listening empathetically to patients. During these interviews, MHPs attempted to build a trusting human-centered relationship while collecting data necessary for professional medical and psychiatric care. Often, because of the social stigma of mental health disorders, patient discomfort in discussing their presenting problem may add additional complexities and nuances to the language they use, that is, hidden signals among noisy content. Therefore, a focused, well-formed, and elaborative summary of clinical interviews is critical to MHPs in making informed decisions by enabling a more profound exploration of a patient's behavior, especially when it endangers life.
    Objective: The aim of this study is to propose an unsupervised, knowledge-infused abstractive summarization (KiAS) approach that generates summaries to enable MHPs to perform a well-informed follow-up with patients to improve the existing summarization methods built on frequency heuristics by creating more informative summaries.
    Methods: Our approach incorporated domain knowledge from the Patient Health Questionnaire-9 lexicon into an integer linear programming framework that optimizes linguistic quality and informativeness. We used 3 baseline approaches: extractive summarization using the SumBasic algorithm, abstractive summarization using integer linear programming without the infusion of knowledge, and abstraction over extractive summarization to evaluate the performance of KiAS. The capability of KiAS on the Distress Analysis Interview Corpus-Wizard of Oz data set was demonstrated through interpretable qualitative and quantitative evaluations.
    Results: KiAS generates summaries (7 sentences on average) that capture informative questions and responses exchanged during long (58 sentences on average), ambiguous, and sparse clinical diagnostic interviews. The summaries generated using KiAS improved upon the 3 baselines by 23.3%, 4.4%, 2.5%, and 2.2% for thematic overlap, Flesch Reading Ease, contextual similarity, and Jensen Shannon divergence, respectively. On the Recall-Oriented Understudy for Gisting Evaluation-2 and Recall-Oriented Understudy for Gisting Evaluation-L metrics, KiAS showed an improvement of 61% and 49%, respectively. We validated the quality of the generated summaries through visual inspection and substantial interrater agreement from MHPs.
    Conclusions: Our collaborator MHPs observed the potential utility and significant impact of KiAS in leveraging valuable but voluminous communications that take place outside of normally scheduled clinical appointments. This study shows promise in generating semantically relevant summaries that will help MHPs make informed decisions about patient status.
    Language English
    Publishing date 2021-05-10
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2798262-2
    ISSN 2368-7959
    ISSN 2368-7959
    DOI 10.2196/20865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Factors Contributing to Adolescents' and Young Adults' Participation in Web-Based Challenges: Survey Study.

    Khasawneh, Amro / Chalil Madathil, Kapil / Zinzow, Heidi / Rosopa, Patrick / Natarajan, Gitanjali / Achuthan, Krishnashree / Narasimhan, Meera

    JMIR pediatrics and parenting

    2021  Volume 4, Issue 1, Page(s) e24988

    Abstract: Background: Web-based challenges, phenomena that are familiar to adolescents and young adults who spend large amounts of time on social media, range from minimally harmful behaviors intended to support philanthropic endeavors to significantly harmful ... ...

    Abstract Background: Web-based challenges, phenomena that are familiar to adolescents and young adults who spend large amounts of time on social media, range from minimally harmful behaviors intended to support philanthropic endeavors to significantly harmful behaviors that may culminate in injury or death.
    Objective: This study aims to investigate the beliefs that lead adolescents and young adults to participate in these activities by analyzing the amyotrophic lateral sclerosis (ALS) ice bucket challenge, representing nonharmful behaviors associated with web-based challenges, and the cinnamon challenge, representing web-based challenges that lead to harmful behaviors.
    Methods: A retrospective quantitative study was conducted with a total of 471 participants aged between 13 and 35 years who either had participated in the ALS ice bucket challenge or the cinnamon challenge, or had never participated in any web-based challenge. Binomial logistic regression models were used to classify those who participated in the ALS ice bucket challenge or cinnamon challenge versus those who did not engage in either challenge using the integrated behavioral model's beliefs as predictors.
    Results: The findings showed that participants of both the cinnamon challenge and the ALS ice bucket challenge had significantly greater expectations from the public to participate in the challenge they completed in comparison with individuals who never participated in any challenge (P=.01 for the cinnamon challenge and P=.003 for the ALS ice bucket challenge). Cinnamon challenge participants had greater value for the outcomes of the challenge (P<.001) and perceived positive public opinion about the challenge (P<.001), in comparison with individuals who never participated in any challenge. In contrast, ALS ice bucket challenge participants had significantly greater positive emotional responses than individuals who never participated in any challenge (P<.001).
    Conclusions: The constructs that contribute to the spread of web-based challenges vary based on the level of self-harm involved in the challenge and its purpose. Intervention efforts could be tailored to address the beliefs associated with different types of web-based challenges.
    Language English
    Publishing date 2021-02-17
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-6722
    ISSN (online) 2561-6722
    DOI 10.2196/24988
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Herding cats and other epic challenges: Creating meaningful stakeholder engagement in community mental health research.

    Pandi-Perumal, Seithikurippu R / Zeller, John L / Parthasarathy, Sairam / Edward Freeman, R / Narasimhan, Meera

    Asian journal of psychiatry

    2019  Volume 42, Page(s) 19–21

    Abstract: Stakeholder-centered approaches, that restrict patient barriers to clinical community mental health research, affect outcomes. It is suggested that a restructuring of clinical research organizational behavior and attitudes may overcome this problem. It ... ...

    Abstract Stakeholder-centered approaches, that restrict patient barriers to clinical community mental health research, affect outcomes. It is suggested that a restructuring of clinical research organizational behavior and attitudes may overcome this problem. It is further advocated that consultation with an engagement of study patient stakeholders encourages their interest in the study, and is essential for successful research. This editorial considers the concept of stakeholder participation and management in the clinical research environment. It further offers practical suggestions for fostering meaningful stakeholder engagement.
    MeSH term(s) Community-Based Participatory Research ; Humans ; Mental Health ; Patient Participation ; Stakeholder Participation
    Language English
    Publishing date 2019-03-26
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2019.03.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: How Different Pre-existing Mental Disorders and Their Co-occurrence Affects COVID-19 Clinical Outcomes? A Real-World Data Study in the Southern United States.

    Qiao, Shan / Zhang, Jiajia / Chen, Shujie / Olatosi, Bankole / Hardeman, Suzanne / Narasimhan, Meera / Bruner, Larisa / Diedhiou, Abdoulaye / Scott, Cheryl / Mansaray, Ali / Weissman, Sharon / Li, Xiaoming

    Frontiers in public health

    2022  Volume 10, Page(s) 831189

    Abstract: Background: Although a psychiatric history might be an independent risk factor for COVID-19 infection and mortality, no studies have systematically investigated how different clusters of pre-existing mental disorders may affect COVID-19 clinical ... ...

    Abstract Background: Although a psychiatric history might be an independent risk factor for COVID-19 infection and mortality, no studies have systematically investigated how different clusters of pre-existing mental disorders may affect COVID-19 clinical outcomes or showed how the coexistence of mental disorder clusters is related to COVID-19 clinical outcomes.
    Methods: Using a retrospective cohort study design, a total of 476,775 adult patients with lab-confirmed and probable COVID-19 between March 06, 2020 and April 14, 2021 in South Carolina, United States were included in the current study. The electronic health record data of COVID-19 patients were linked to all payer-based claims data through the SC Revenue and Fiscal Affairs Office. Pre-existing mental disorder diagnoses from Jan 2, 2019 to Jan 14, 2021 were extracted from the patients' healthcare utilization data via ICD-10 codes.
    Results: There is an elevated risk of COVID-19-related hospitalization and death among participants with pre-existing mental disorders adjusting for key socio-demographic and comorbidity covariates. Co-occurrence of any two clusters was positively associated with COVID-19-related hospitalization and death. The odds ratio of being hospitalized was 1.26 (95% CI: 1.151, 1.383) for patients with internalizing and externalizing disorders, 1.65 (95% CI: 1.298, 2.092) for internalizing and thought disorders, 1.76 (95% CI: 1.217, 2.542) for externalizing and thought disorders, and 1.64 (95% CI: 1.274, 2.118) for three clusters of mental disorders.
    Conclusions: Pre-existing internalizing disorders and thought disorders are positively related to COVID-19 hospitalization and death. Co-occurrence of any two clusters of mental disorders have elevated risk of COVID-19-related hospitalization and death compared to those with a single cluster.
    MeSH term(s) Adult ; COVID-19/epidemiology ; Comorbidity ; Humans ; Mental Disorders/epidemiology ; Preexisting Condition Coverage ; Retrospective Studies ; United States/epidemiology
    Language English
    Publishing date 2022-06-16
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.831189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A tale of two comorbidities: Understanding the neurobiology of depression and pain.

    Narasimhan, Meera / Campbell, Nioaka

    Indian journal of psychiatry

    2010  Volume 52, Issue 2, Page(s) 127–130

    Abstract: The comorbidity of chronic pain and depression has been consistently associated with a poor prognosis and greater disability in patients as compared to those suffering from each illness alone. This further has implications on significant financial costs ... ...

    Abstract The comorbidity of chronic pain and depression has been consistently associated with a poor prognosis and greater disability in patients as compared to those suffering from each illness alone. This further has implications on significant financial costs to the patients and to our society. The biological underpinnings of major depression and chronic pain have considerable overlap in the areas of genetic, structural, functional, neuroendocrine and neurotransmitter functionality. Although the field has evolved in the past decade, more efforts should now focus on understanding the biological underpinnings of this shared comorbidity, while shedding light on treatment implications for these two devastating conditions.
    Language English
    Publishing date 2010-08-30
    Publishing country India
    Document type Journal Article
    ZDB-ID 221523-8
    ISSN 1998-3794 ; 0019-5545
    ISSN (online) 1998-3794
    ISSN 0019-5545
    DOI 10.4103/0019-5545.64586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Treating depression and achieving remission.

    Narasimhan, Meera / Kannaday, Melissa H

    Asian journal of psychiatry

    2010  Volume 3, Issue 4, Page(s) 163–168

    Abstract: Despite all the advances in understanding the biological underpinnings of depression and the extensive armamentarium of antidepressants remission is a difficult goal to achieve. This in turn impacts the social and occupational functioning and the quality ...

    Abstract Despite all the advances in understanding the biological underpinnings of depression and the extensive armamentarium of antidepressants remission is a difficult goal to achieve. This in turn impacts the social and occupational functioning and the quality of life. There are several hurdles to achieving remission including accuracy of diagnosis, partial response, suboptimization of the medication, and failure to capture residual symptoms. There is an urgent need to implement strategies to achieve remission including destigmatizing mental illness, educating patients, their families, optimizing treatments, exploring novel interventions and addressing residual symptoms.
    Language English
    Publishing date 2010-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2010.10.004
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  10. Article ; Online: Adherence according to Mary Poppins: strategies to make the medicine go down.

    Hardeman, Suzanne M / Narasimhan, Meera

    Perspectives in psychiatric care

    2010  Volume 46, Issue 1, Page(s) 3–13

    Abstract: Purpose: This article reviews the prevalence, risk factors, and burden of nonadherence in mood and psychotic disorders, and presents evidence-based, disease-specific strategies shown to improve adherence.: Conclusion: A comprehensive approach based ... ...

    Abstract Purpose: This article reviews the prevalence, risk factors, and burden of nonadherence in mood and psychotic disorders, and presents evidence-based, disease-specific strategies shown to improve adherence.
    Conclusion: A comprehensive approach based on the goal of remission, designed around the patient's individual needs, facilitates adherence, leads to improved quality of life, and reduces disease burden.
    Practice implications: Adherence in mood and psychotic disorders can be improved when providers take time to build trusting relationships; identify risk factors; anticipate nonadherence; individualize treatment; and educate patients, families, and other healthcare providers.
    MeSH term(s) Chronic Disease ; Cross-Sectional Studies ; Humans ; Medication Adherence/psychology ; Medication Adherence/statistics & numerical data ; Medication Therapy Management/organization & administration ; Mental Disorders/drug therapy ; Mental Disorders/nursing ; Mental Disorders/psychology ; Motivation ; Nursing Assessment ; Patient Education as Topic ; Psychotropic Drugs/administration & dosage ; Psychotropic Drugs/adverse effects ; United States
    Chemical Substances Psychotropic Drugs
    Language English
    Publishing date 2010-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391097-0
    ISSN 1744-6163 ; 0031-5990
    ISSN (online) 1744-6163
    ISSN 0031-5990
    DOI 10.1111/j.1744-6163.2009.00233.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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