LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 5 of total 5

Search options

  1. Article ; Online: Performance monitoring and error detection: The role of mid frontal theta and error-related negativity (ERN) among Indian adolescents from different socioeconomic background.

    Raturi, Aman Kumar / Narayanan, Sreelatha S / Jena, S P K

    Applied neuropsychology. Child

    2024  , Page(s) 1–13

    Abstract: The aim of the study was to investigate the relationship between socioeconomic status (SES) and executive functioning, focusing specifically on performance monitoring, error detection, and their association with mid-frontal theta and error-related ... ...

    Abstract The aim of the study was to investigate the relationship between socioeconomic status (SES) and executive functioning, focusing specifically on performance monitoring, error detection, and their association with mid-frontal theta and error-related negativity (ERN). Employing the widely used flanker task, the research involved two phases with participants aged 10-16 years (15 individuals in the pilot phase and 35 in the second phase). Electroencephalogram (EEG) recordings from distinct brain regions were analyzed during various conditions. The study revealed a notable increase in both absolute and relative theta power at Fcz during the flanker task, with a stronger effect observed during incorrect trials. Furthermore, it underscored the influence of socioeconomic status (SES) on mid-frontal theta, highlighting interactions between SES, gender, and experimental conditions impacting both absolute and relative theta. Intriguingly, the research disclosed a positive correlation between parental occupation and error-related negativity (ERN), as well as between age and ERN. These findings underscore the significance of SES, gender, and age in shaping the neural mechanisms associated with performance monitoring and executive functions. The study contributes valuable insights into the intricate interplay between socio-demographic factors and cognitive processes, shedding light on their impact on goal-directed behaviors and brain activity.
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2673759-0
    ISSN 2162-2973 ; 2162-2965
    ISSN (online) 2162-2973
    ISSN 2162-2965
    DOI 10.1080/21622965.2024.2333809
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6962: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Why parents consent to their children's participation in genetic research: A study of parental decision making.

    Kumari, Sunita / Bhatia, Triptish / Mishra, Nagendra N / Kumari, Nupur / Narayanan, Sreelatha S / Malik, Deepak / Deshpande, Smita N

    Indian journal of medical ethics

    2019  Volume 4 NS, Issue 4

    Abstract: Parents need to be asked to provide informed consent on behalf of their child for participation in genetic research. Decision making for such parents is difficult because ethical challenges in paediatric genetic research studies are different from ... ...

    Abstract Parents need to be asked to provide informed consent on behalf of their child for participation in genetic research. Decision making for such parents is difficult because ethical challenges in paediatric genetic research studies are different from similar adult studies. This paper focuses on interviews conducted with parents who were asked to consent to their children's participation (or not) in a genetic research study of intellectual disability and/or autism.
    MeSH term(s) Adolescent ; Adult ; Child ; Child, Preschool ; Decision Making/ethics ; Female ; Genetic Research/ethics ; Humans ; India ; Infant ; Infant, Newborn ; Informed Consent By Minors/ethics ; Male ; Middle Aged ; Parents/psychology ; Patient Participation/psychology ; Surveys and Questionnaires
    Language English
    Publishing date 2019-12-02
    Publishing country India
    Document type Journal Article
    ISSN 0975-5691
    ISSN (online) 0975-5691
    DOI 10.20529/IJME.2019.063
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: A case control study of association between cognition and functional capacity in schizophrenia.

    Narayanan, Sreelatha S / Bhatia, Triptish / Velligan, Dawn I / Nimgaonkar, Vishwajit L / Deshpande, Smita N

    Schizophrenia research

    2015  Volume 169, Issue 1-3, Page(s) 165–168

    Abstract: Background: Cognitive functions are important prognostic factors for schizophrenia (SZ), while ability to perform activities of daily living are important measures of functional capacity. The relationship between cognition and functional capacity has ... ...

    Abstract Background: Cognitive functions are important prognostic factors for schizophrenia (SZ), while ability to perform activities of daily living are important measures of functional capacity. The relationship between cognition and functional capacity has not been tested extensively in India.
    Objective: To compare persons with SZ with controls on measures of cognition and functional capacity, and evaluate correlations between cognitive performance and functional capacity.
    Method: Schizophrenia outpatients and controls without psychiatric illness (DSM IV) who completed the MATRICS Consensus Cognitive Battery and Functional Assessment Battery comprised of two tests from University of California San Diego (UCSD) Performance Based Skill Assessment (UPSA), one Test of Adaptive Behavior in Schizophrenia (TABS) and one test from University of California San Diego Performance Based Skill Assessment Brief edition (UPSA-B). Cognitive and functional domains were examined using regression analyses, with relevant covariates.
    Results: Cases (N=51) though younger, were more educated than controls (N=41). Adjusting for education, controls performed better than cases in 3/7 cognitive and 4/5 domains of functional capacity but similarly in 'household management'. Among both cases and controls, cognitive measures of verbal learning and speed of processing overlapped with functional capacity (3 domains). Working memory was associated with one functional domain.
    Conclusions: Consistent with other studies, Indian patients with schizophrenia performed worse than controls on several domains of cognition and functional capacity; these domains were correlated. Speed of processing and verbal learning are most frequently associated with functional capacity indices and should be targeted to improve skills of daily living among persons with SZ.
    MeSH term(s) Adolescent ; Adult ; Case-Control Studies ; Cognition Disorders/etiology ; Communication ; Female ; Humans ; Linear Models ; Male ; Middle Aged ; Neuropsychological Tests ; Psychiatric Status Rating Scales ; Schizophrenia/complications ; Schizophrenic Psychology ; Statistics, Nonparametric ; Young Adult
    Language English
    Publishing date 2015-10-31
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2015.10.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2351: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 543: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: (with research data) Mental illness, poverty and stigma in India: a case-control study.

    Trani, Jean-Francois / Bakhshi, Parul / Kuhlberg, Jill / Narayanan, Sreelatha S / Venkataraman, Hemalatha / Mishra, Nagendra N / Groce, Nora E / Jadhav, Sushrut / Deshpande, Smita

    BMJ open

    2015  Volume 5, Issue 2, Page(s) e006355

    Abstract: Objective: To assess the effect of experienced stigma on depth of multidimensional poverty of persons with severe mental illness (PSMI) in Delhi, India, controlling for gender, age and caste.: Design: Matching case (hospital)-control (population) ... ...

    Abstract Objective: To assess the effect of experienced stigma on depth of multidimensional poverty of persons with severe mental illness (PSMI) in Delhi, India, controlling for gender, age and caste.
    Design: Matching case (hospital)-control (population) study.
    Setting: University Hospital (cases) and National Capital Region (controls), India.
    Participants: A case-control study was conducted from November 2011 to June 2012. 647 cases diagnosed with schizophrenia or affective disorders were recruited and 647 individuals of same age, sex and location of residence were matched as controls at a ratio of 1:2:1. Individuals who refused consent or provided incomplete interview were excluded.
    Main outcome measures: Higher risk of poverty due to stigma among PSMI.
    Results: 38.5% of PSMI compared with 22.2% of controls were found poor on six dimensions or more. The difference in multidimensional poverty index was 69% between groups with employment and income of the main contributors. Multidimensional poverty was strongly associated with stigma (OR 2.60, 95% CI 1.27 to 5.31), scheduled castes/scheduled tribes/other backward castes (2.39, 1.39 to 4.08), mental illness (2.07, 1.25 to 3.41) and female gender (1.87, 1.36 to 2.58). A significant interaction between stigma, mental illness and gender or caste indicates female PSMI or PSMI from 'lower castes' were more likely to be poor due to stigma than male controls (p<0.001) or controls from other castes (p<0.001).
    Conclusions: Public stigma and multidimensional poverty linked to SMI are pervasive and intertwined. In particular for low caste and women, it is a strong predictor of poverty. Exclusion from employment linked to negative attitudes and lack of income are the highest contributors to multidimensional poverty, increasing the burden for the family. Mental health professionals need to be aware of and address these issues.
    MeSH term(s) Case-Control Studies ; Employment ; Female ; Humans ; Income ; India ; Male ; Mentally Ill Persons ; Mood Disorders/economics ; Poverty ; Rural Population ; Schizophrenia/economics ; Sex Factors ; Social Class ; Social Stigma
    Language English
    Publishing date 2015-02-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2747269-3
    ISSN 2044-6055 ; 2044-6055 ; 2053-3624
    ISSN (online) 2044-6055
    ISSN 2044-6055 ; 2053-3624
    DOI 10.1136/bmjopen-2014-006355
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Emotion discrimination in humans: Its association with HSV-1 infection and its improvement with antiviral treatment.

    Bhatia, Triptish / Wood, Joel / Iyengar, Satish / Narayanan, Sreelatha S / Beniwal, Ram Pratap / Prasad, Konasale M / Chen, Kehui / Yolken, Robert H / Dickerson, Faith / Gur, Ruben C / Gur, Raquel E / Deshpande, Smita N / Nimgaonkar, Vishwajit L

    Schizophrenia research

    2017  Volume 193, Page(s) 161–167

    Abstract: Background: Herpes simplex virus, type 1 (HSV-1) infects over 3.4 billion people, world-wide. Though it can cause encephalitis, in the vast majority it is asymptomatic, with lifelong latent infection in neurons. HSV-1 infected individuals have greater ... ...

    Abstract Background: Herpes simplex virus, type 1 (HSV-1) infects over 3.4 billion people, world-wide. Though it can cause encephalitis, in the vast majority it is asymptomatic, with lifelong latent infection in neurons. HSV-1 infected individuals have greater cognitive dysfunction than uninfected individuals, particularly persons with schizophrenia - even without encephalitis. We investigated whether HSV-1 related cognitive dysfunction is progressive or remediable.
    Methods: In a prospective naturalistic follow up sample (PNFU), temporal changes in cognitive functions were analyzed in relation to baseline HSV-1 infection in persons with/without schizophrenia (N=226). Independently, in a randomized controlled trial (RCT), HSV-1 infected, clinically stabilized SZ outpatients received Valacyclovir (VAL, an HSV-1 specific antiviral, 1.5G twice daily for 16weeks) or placebo (PLA) added to standard antipsychotic treatment, using a stratified randomization design, following placebo run-in (N=67). In both samples, HSV-1 infection (seropositivity) was estimated using serum IgG antibodies. Clinical evaluations were blinded to HSV-1 or treatment status. Standardized Z scores for accuracy on eight cognitive domains were analyzed for temporal trajectories using generalized linear models (PNFU) and VAL/PLA differences compared with intent to treat analyses (RCT).
    Results: PNFU: At baseline, HSV-1 infected participants had significantly lower accuracy scores for Emotion Identification and Discrimination (EMOD), Spatial memory and Spatial ability, regardless of SZ diagnosis (p=0.025, 0.029, 0.046, respectively). They also had significantly steeper temporal worsening for EMOD (p=0.03). RCT: EMOD improved in VAL-treated patients (p=0.048, Cohen's d=0.43).
    Conclusions: A proportion of age related decline in EMOD is attributable to HSV-1 infection.
    MeSH term(s) Acyclovir/analogs & derivatives ; Acyclovir/therapeutic use ; Adolescent ; Adult ; Antipsychotic Agents/therapeutic use ; Antiviral Agents/therapeutic use ; Cognition Disorders/drug therapy ; Cognition Disorders/etiology ; Cognition Disorders/virology ; Emotions/drug effects ; Female ; Follow-Up Studies ; Herpes Simplex/complications ; Herpes Simplex/drug therapy ; Humans ; Male ; Middle Aged ; Neuropsychological Tests ; Randomized Controlled Trials as Topic ; Severity of Illness Index ; Valacyclovir ; Valine/analogs & derivatives ; Valine/therapeutic use ; Young Adult
    Chemical Substances Antipsychotic Agents ; Antiviral Agents ; Valine (HG18B9YRS7) ; Valacyclovir (MZ1IW7Q79D) ; Acyclovir (X4HES1O11F)
    Language English
    Publishing date 2017-08-19
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2017.08.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2351: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 543: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top