LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 5 of total 5

Search options

  1. Article ; Online: Adalimumab-induced leukocytoclastic vasculitis in a Crohn's disease patient.

    Cançado, Guilherme G L / Nardelli, Mateus J / Gouthier, Mabely A D

    European journal of gastroenterology & hepatology

    2021  Volume 33, Issue 3, Page(s) 453

    MeSH term(s) Adalimumab/adverse effects ; Crohn Disease/diagnosis ; Crohn Disease/drug therapy ; Humans ; Vasculitis, Leukocytoclastic, Cutaneous/chemically induced ; Vasculitis, Leukocytoclastic, Cutaneous/diagnosis
    Chemical Substances Adalimumab (FYS6T7F842)
    Language English
    Publishing date 2021-01-29
    Publishing country England
    Document type Letter
    ZDB-ID 1034239-4
    ISSN 1473-5687 ; 0954-691X
    ISSN (online) 1473-5687
    ISSN 0954-691X
    DOI 10.1097/MEG.0000000000001945
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2932: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Sarcopenia, body composition and factors associated with variceal gastrointestinal bleeding and splenectomy in hepatosplenic schistosomiasis mansoni.

    Barbosa, Fernanda A / Nardelli, Mateus J / Cançado, Guilherme G L / Silva, Catherine F / Osório, Fernanda M F / Melo, Rodolfo F Q / Taranto, Daniela O L / Ferrari, Teresa C A / Couto, Claudia A / Faria, Luciana C

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2022  Volume 116, Issue 12, Page(s) 1145–1153

    Abstract: Background: Sarcopenia is a common complication of cirrhosis and an important predictor of morbimortality. We aimed to determine the prevalence of sarcopenia and its associated factors in hepatosplenic schistosomiasis (HSS) as well as to evaluate ... ...

    Abstract Background: Sarcopenia is a common complication of cirrhosis and an important predictor of morbimortality. We aimed to determine the prevalence of sarcopenia and its associated factors in hepatosplenic schistosomiasis (HSS) as well as to evaluate whether muscle mass and function are associated with variceal upper gastrointestinal bleeding (VUGIB) and previous splenectomy in subjects without other liver diseases.
    Methods: We conducted a cross-sectional study including adults with HSS who underwent clinical, biochemical, anthropometric, muscle strength and physical performance evaluations and were submitted to bioelectrical impedance analysis and abdominal ultrasound. Sarcopenia was diagnosed according to the 2019 European consensus criteria.
    Results: A total of 66 patients with HSS (62.1% male; mean age 48.8±8.6 y) were included. Overall, six subjects (9.1%) were diagnosed with probable sarcopenia and none had confirmed sarcopenia. Fat-free body mass index (BMI) was independently associated with VUGIB (odds ratio 0.701 [95% confidence interval 0.51 to 0.96]; p=0.025). Compared with patients who did not undergo surgery, individuals who underwent esophagogastric devascularization combined with splenectomy (EGDS) had higher serum lipid levels, fat percentage and frequency of metabolic syndrome, with lower skeletal muscle mass index and hand grip strength.
    Conclusions: HSS mansoni seems not to cause sarcopenia. However, a lower fat-free BMI was associated with previous VUGIB and the subgroup of patients who underwent EGDS presented higher lipid levels, fat percentage and frequency of metabolic syndrome and lower muscle mass and function.
    MeSH term(s) Adult ; Humans ; Male ; Middle Aged ; Female ; Splenectomy/adverse effects ; Schistosomiasis mansoni/complications ; Schistosomiasis mansoni/surgery ; Sarcopenia/complications ; Sarcopenia/diagnostic imaging ; Sarcopenia/epidemiology ; Cross-Sectional Studies ; Metabolic Syndrome/complications ; Hand Strength ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/complications ; Splenic Diseases/epidemiology ; Splenic Diseases/etiology ; Splenic Diseases/surgery ; Body Composition ; Schistosomiasis/complications ; Lipids
    Chemical Substances Lipids
    Language English
    Publishing date 2022-06-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1093/trstmh/trac052
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.257: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Portal vein thrombosis in patients with hepatosplenic schistosomiasis who underwent oesophagogastric devascularization combined with splenectomy.

    Cançado, Guilherme G L / Nardelli, Mateus J / Barbosa, Fernanda A / Silva, Catherine F / Osório, Fernanda M F / Ferrari, Teresa C A / Couto, Claudia A / Faria, Luciana C

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2021  Volume 115, Issue 9, Page(s) 1004–1009

    Abstract: Background: Portal vein thrombosis (PVT) has been described in nearly 50% of patients who underwent oesophagogastric devascularization combined with splenectomy (EGDS), but no previous study has compared its occurrence in surgical and non-surgical ... ...

    Abstract Background: Portal vein thrombosis (PVT) has been described in nearly 50% of patients who underwent oesophagogastric devascularization combined with splenectomy (EGDS), but no previous study has compared its occurrence in surgical and non-surgical groups. This study aimed to investigate PVT in hepatosplenic schistosomiasis (HSS) and its association with EGDS and upper variceal bleeding (UVB).
    Methods: Retrospectively, 104 HSS individuals were enrolled. Following EGDS, the occurrence of PVT, mesenteric vein thrombosis (MVT), hospital admissions and UVB were recorded.
    Results: EGDS was performed in 27 (26%) patients. PVT and MVT were detected in 30 (33%) and 8 (9.8%) patients, respectively. Patients who underwent EGDS were at greater risk of PVT (63% vs 19.7%; odds ratio [OR] 6.12 [95% confidence interval {CI} 2.3 to 16.1], p<0.001) when compared with a non-surgical approach. There was no significant difference in UVB occurrence and β-blocker usage. PVT was associated with more hospital admissions (p=0.030) and higher alkaline phosphatase levels (p=0.008). UVB occurrence in patients with and without thrombosis was similar. In multivariate analysis, after adjustment, PVT was associated with the surgical approach (OR 4.56 [95% CI 1.55 to 13.38], p=0.006) and age at HSS diagnosis (OR 0.94 [95% CI 0.90 to 0.99], p=0.021).
    Conclusions: EGDS was not associated with a decreased frequency of UVB when compared with the non-surgical approach but was an independent risk factor for PVT.
    MeSH term(s) Esophageal and Gastric Varices/pathology ; Gastrointestinal Hemorrhage/epidemiology ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/pathology ; Humans ; Liver Cirrhosis/pathology ; Portal Vein/pathology ; Retrospective Studies ; Schistosomiasis/complications ; Splenectomy/adverse effects
    Language English
    Publishing date 2021-01-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1093/trstmh/trab013
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.257: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Liver stiffness is able to differentiate hepatosplenic Schistosomiasis mansoni from liver cirrhosis and spleen stiffness may be a predictor of variceal bleeding in hepatosplenic schistosomiasis.

    Silva, Catherine F / Nardelli, Mateus J / Barbosa, Fernanda A / Galizzi, Humberto O / Cal, Tereza C M F / Ferrari, Teresa C A / Faria, Luciana C / Couto, Claudia A

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2021  Volume 116, Issue 1, Page(s) 26–33

    Abstract: Background: Ultrasonography is limited for differentiating portal hypertension due to liver cirrhosis from that secondary to hepatosplenic schistosomiasis (HSS). We aimed to investigate the role of transient elastography (TE) in differentiating HSS ... ...

    Abstract Background: Ultrasonography is limited for differentiating portal hypertension due to liver cirrhosis from that secondary to hepatosplenic schistosomiasis (HSS). We aimed to investigate the role of transient elastography (TE) in differentiating HSS mansoni from cirrhosis and the factors associated with liver and spleen stiffness (LS and SS) in HSS.
    Method: A cross-sectional study was conducted including patients with HSS mansoni (n=29) and liver cirrhosis due to non-alcoholic steatohepatitis (n=23). All patients underwent TE and those with HSS were assessed by the Niamey protocol.
    Results: HSS subjects presented lower median LS (9.6 vs 21.3 Kpa, p<0.001) and liver controlled attenuation parameter (229 vs 274 dB/m, p=0.010) than cirrhosis subjects, in addition to higher SS (73.5 vs 42.2 Kpa, p=0.002). The area under the receiver operating characteristic curve for detecting cirrhosis by LS was 0.947 (95% CI 0.89 to 1.00, p<0.001), with an optimal cut-off of 11.75 Kpa. In HSS subjects, higher SS was associated with the presence of the following: diabetes mellitus (p=0.036), metabolic syndrome (p=0.043), esophageal varices (p=0.001), portal vein thrombosis (p=0.047) and previous variceal bleeding (p=0.011). In HSS patients without portal vein thrombosis, variceal bleeding was associated with higher SS (p=0.018). Niamey categories were not associated with LS (p=0.676) or SS (p=0.504).
    Conclusion: TE can play a role in differentiating HSS from cirrhosis, especially by LS. SS may be further investigated for predicting complications in HSS.
    MeSH term(s) Cross-Sectional Studies ; Esophageal and Gastric Varices/diagnostic imaging ; Esophageal and Gastric Varices/etiology ; Fascioliasis ; Gastrointestinal Hemorrhage/diagnostic imaging ; Gastrointestinal Hemorrhage/etiology ; Humans ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/diagnostic imaging ; Schistosomiasis/complications ; Schistosomiasis mansoni/diagnosis ; Schistosomiasis mansoni/diagnostic imaging ; Spleen/diagnostic imaging ; Thrombosis/complications
    Language English
    Publishing date 2021-03-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1093/trstmh/trab041
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.257: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Genetic Ancestry, Race, and Severity of Acutely Decompensated Cirrhosis in Latin America.

    Farias, Alberto Queiroz / Curto Vilalta, Anna / Momoyo Zitelli, Patricia / Pereira, Gustavo / Goncalves, Luciana L / Torre, Aldo / Diaz, Juan Manuel / Gadano, Adrian C / Mattos, Angelo Z / Mendes, Liliana S C / Alvares-da-Silva, Mario R / Bittencourt, Paulo L / Benitez, Carlos / Couto, Claudia Alves / Mendizabal, Manuel / Toledo, Claudio L / Mazo, Daniel F C / Castillo Barradas, Mauricio / Uson Raposo, Eva M /
    Padilla-Machaca, P Martín / Zarela Lozano Miranda, Adelina / Malé-Velázquez, René / Castro Lyra, André / Dávalos-Moscol, Milagros B / Pérez Hernández, José L / Ximenes, Rafael O / Faria Silva, Giovanni / Beltrán-Galvis, Oscar A / González Huezo, María S / Bessone, Fernando / Rocha, Tarciso D S / Fassio, Eduardo / Terra, Carlos / Marín, Juan I / Sierra Casas, Patricia / de la Peña-Ramirez, Carlos / Aguilar Parera, Ferran / Fernandes, Flavia / da Penha Zago-Gomes, Maria / Méndez-Guerrero, Osvely / Marciano, Sebastián / Mattos, Angelo A / Oliveira, Joao C / Guerreiro, Gabriel T S / Codes, Liana / Arrese, Marco / Nardelli, Mateus J / Silva, Marcelo O / Palma-Fernandez, Renato / Alcantara, Camila / Sánchez Garrido, Cristina / Trebicka, Jonel / Gustot, Thierry / Fernández, Javier / Clària, Joan / Jalan, Rajiv / Angeli, Paolo / Arroyo, Vicente / Moreau, Richard / Carrilho, Flair J

    Gastroenterology

    2023  Volume 165, Issue 3, Page(s) 696–716

    Abstract: Background & aims: Genetic ancestry or racial differences in health outcomes exist in diseases associated with systemic inflammation (eg, COVID-19). This study aimed to investigate the association of genetic ancestry and race with acute-on-chronic liver ...

    Abstract Background & aims: Genetic ancestry or racial differences in health outcomes exist in diseases associated with systemic inflammation (eg, COVID-19). This study aimed to investigate the association of genetic ancestry and race with acute-on-chronic liver failure (ACLF), which is characterized by acute systemic inflammation, multi-organ failure, and high risk of short-term death.
    Methods: This prospective cohort study analyzed a comprehensive set of data, including genetic ancestry and race among several others, in 1274 patients with acutely decompensated cirrhosis who were nonelectively admitted to 44 hospitals from 7 Latin American countries.
    Results: Three hundred ninety-five patients (31.0%) had ACLF of any grade at enrollment. Patients with ACLF had a higher median percentage of Native American genetic ancestry and lower median percentage of European ancestry than patients without ACLF (22.6% vs 12.9% and 53.4% vs 59.6%, respectively). The median percentage of African genetic ancestry was low among patients with ACLF and among those without ACLF. In terms of race, a higher percentage of patients with ACLF than patients without ACLF were Native American and a lower percentage of patients with ACLF than patients without ACLF were European American or African American. In multivariable analyses that adjusted for differences in sociodemographic and clinical characteristics, the odds ratio for ACLF at enrollment was 1.08 (95% CI, 1.03-1.13) with Native American genetic ancestry and 2.57 (95% CI, 1.84-3.58) for Native American race vs European American race CONCLUSIONS: In a large cohort of Latin American patients with acutely decompensated cirrhosis, increasing percentages of Native American ancestry and Native American race were factors independently associated with ACLF at enrollment.
    MeSH term(s) Humans ; Latin America/epidemiology ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/epidemiology ; Liver Cirrhosis/genetics ; Prospective Studies ; COVID-19/complications ; Acute-On-Chronic Liver Failure/diagnosis ; Acute-On-Chronic Liver Failure/epidemiology ; Acute-On-Chronic Liver Failure/genetics ; Inflammation/complications ; Prognosis
    Language English
    Publishing date 2023-05-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2023.05.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.44: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 572: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top