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  1. Article: Prevalence and Clinical Impact of Immune-Mediated Inflammatory Diseases in Patients with Inflammatory Bowel Disease: Results from a Large Retrospective Observational Study.

    Vernero, Marta / Saibeni, Simone / Scalvini, Davide / Cicalini, Carolina / Chiarello, Lorenzo / Nardi, Silvia / Ribaldone, Davide Giuseppe / Bezzio, Cristina

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: 1) Background: ...

    Abstract (1) Background:
    Language English
    Publishing date 2024-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13041019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Early morbidity after pancreas transplantation.

    Bindi, Maria Lucia / Biancofiore, Gianni / Meacci, Luca / Bellissima, Germana / Nardi, Silvia / Pieri, Marco / Vistoli, Fabio / Boggi, Ugo / Sansevero, Andrea / Mosca, Franco

    Transplant international : official journal of the European Society for Organ Transplantation

    2005  Volume 18, Issue 12, Page(s) 1356–1360

    Abstract: This study aims to evaluate and compare the early outcome of both pancreas-alone transplantation (PTA) and simultaneous kidney-pancreas transplantation (SPKT) focusing on the complications affecting the first month after the procedures. The records of ... ...

    Abstract This study aims to evaluate and compare the early outcome of both pancreas-alone transplantation (PTA) and simultaneous kidney-pancreas transplantation (SPKT) focusing on the complications affecting the first month after the procedures. The records of all patients who underwent PTA or SPKT were reviewed. We considered the length of ICU stay, the need for postoperative ventilatory support, hemodynamic and metabolic data (arterial pH, serum glucose, need for exogenous insulin), infectious diseases incidence, microbiological colonization rate and any kind of postoperative complication arising during the first month after the transplantation. PTA recipients underwent a quicker surgery (P < 0.01) with shorter ICU stay (P < 0.05) and a lower need for postoperative mechanical ventilation (P < 0.05). They also had a higher hemodynamic stability (P < 0.05) with less cardiological complications (P < 0.05) in the intra- and postoperative phases; bacterial colonisation was also less frequent in PTA recipients (P < 0.05). On the contrary, no significant difference was noted with regard to postoperative nausea/vomiting, sudden myocardial death, ICU re-admissions, graft function, rate of rejection, grafts explantation and re-transplantation. PTA could be considered as preemptive for severe diabetic complications in patients with long-lasting severe type I diabetes. However, establishing the correct timing of PTA is of paramount importance in order not to expose the patients early to risks arising from a major surgery and heavy immunosuppressive treatments.
    MeSH term(s) Adult ; Blood Glucose/metabolism ; Female ; Graft Rejection ; Graft Survival ; Hemodynamics ; Humans ; Hydrogen-Ion Concentration ; Immunosuppressive Agents/pharmacology ; Immunosuppressive Agents/therapeutic use ; Insulin/metabolism ; Intensive Care Units ; Kidney Transplantation/adverse effects ; Kidney Transplantation/methods ; Male ; Middle Aged ; Morbidity ; Pancreas Transplantation/adverse effects ; Pancreas Transplantation/methods ; Time Factors ; Treatment Outcome
    Chemical Substances Blood Glucose ; Immunosuppressive Agents ; Insulin
    Language English
    Publishing date 2005-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.1111/j.1432-2277.2005.00222.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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