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  1. Article: Brain Calcifications Secondary to Idiopathic Hyperthyroidism and Hypoparathyroidism.

    Sayeed, Bushra Zafar / Sayeed, Faiza Zafar / Nashit, Muhammad / Bhatty, Shaheen

    Ochsner journal

    2024  Volume 24, Issue 1, Page(s) 53–57

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Case Reports
    ISSN 1524-5012
    ISSN 1524-5012
    DOI 10.31486/toj.23.0004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Case Report of Behcet's Disease With Thromboses in the Superior Vena Cava and External Iliac Vein.

    Sayeed, Faiza Zafar / Nashit, Muhammad / Bhatty, Shaheen / Sayeed, Bushra Z / Asad, Fariha

    Cureus

    2022  Volume 14, Issue 4, Page(s) e24064

    Abstract: Behcet's disease (BD), also known as Behcet's syndrome, is a rare, chronic, autoimmune disorder of unknown origin. Its manifestations are thought to be caused by vasculitis, resulting in damage to blood vessels of all sizes throughout the body. We report ...

    Abstract Behcet's disease (BD), also known as Behcet's syndrome, is a rare, chronic, autoimmune disorder of unknown origin. Its manifestations are thought to be caused by vasculitis, resulting in damage to blood vessels of all sizes throughout the body. We report a 25-year-old Pakistani male who is sexually active and presents with a one-year history of shortness of breath, cough, exertional dyspnea, and neck and facial swelling. On examination, he had severe anemia, mouth ulcers, distended neck and chest veins, prominent abdominal veins, and a scrotal ulcer. After going through mandatory investigations to evaluate the presenting signs and symptoms, thromboses were found in the major veins, including the superior vena cava (SVC) and external iliac vein, as well as a positive pathergy test. Accordingly, a diagnosis of Behcet's disease with cardiomyopathy and venous thrombosis was made. He was treated with anticoagulants, steroids, and azathioprine for six months and subsequently went into remission.
    Language English
    Publishing date 2022-04-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.24064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Is Using the Harmonic Scalpel Better than Conventional Hemostasis in Neck Dissection? A Meta-Analysis.

    Hameed, Ishaque / Khan, Mohammad Omer / Samad, Syed Abdus / Mahmood, Samar / Siddiqui, Omer Mustafa / Hameed, Indallah / Nashit, Muhammad / Iqbal, Ayman / Marsia, Shayan / Al Shetawi, Al Haitham

    Craniomaxillofacial trauma & reconstruction

    2023  Volume 17, Issue 1, Page(s) 74–86

    Abstract: Study design: Systematic review and meta-analysis.: Objective: The clinical decision to pursue harmonic scalpel (HS) method vs conventional hemostasis to treat head and neck cancers has been arguably predicated on the clinical outcomes observed. This ...

    Abstract Study design: Systematic review and meta-analysis.
    Objective: The clinical decision to pursue harmonic scalpel (HS) method vs conventional hemostasis to treat head and neck cancers has been arguably predicated on the clinical outcomes observed. This study aims to evaluate the surgical outcomes of neck dissection between both techniques and perform an updated meta-analysis using the available literature.
    Methods: We searched PubMed, Scopus, and Cochrane Library through 31st December 2021, according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Outcome metrics included operative time and intraoperative blood loss. Secondary outcomes consisted of length of hospital stay, length of drain stay, total drain output, and postoperative complications. A meta-analysis was conducted using Review Manager Version 5.3 (RevMan) software employing the Random Effects Model.
    Results: We identified 114 articles, out of which 10 randomized control trials (RCTs) analyzing a combined total of 558 patients met the inclusion criteria after title and full-text screening. Meta-analysis shows the group treated with HS had a significantly shorter operative time. [MD = -23.21, 95% CI (-34.30, -12.12)
    Conclusions: This study confirms that that HS use in neck dissection yields a reduced operative time and intra operative blood loss relative to conventional hemostasis. Furthermore, our paper shows no superiority of HS method over conventional hemostasis where length of hospital stays, length of drain stays, and postoperative complications are concerned. Future RCTs with high-level evidence may further elucidate the relative effectiveness of HS method over conventional hemostasis in treating head and neck cancers.
    Language English
    Publishing date 2023-04-15
    Publishing country United States
    Document type Journal Article
    ISSN 1943-3875
    ISSN 1943-3875
    DOI 10.1177/19433875231170924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Is it safe and effective to administer COVID-19 vaccines during pregnancy? A systematic review and meta-analysis.

    Hameed, Ishaque / Khan, Mohammad Omer / Nusrat, Khushboo / Mahmood, Samar / Nashit, Muhammad / Malik, Shanza / Siddiqui, Omer Mustafa / Samad, Syed Abdus / Marsia, Shayan / Usman, Muhammad Shariq / Siddiqi, Tariq Jamal

    American journal of infection control

    2022  Volume 51, Issue 5, Page(s) 582–593

    Abstract: Objective: To evaluate the safety and efficacy of COVID-19 vaccines in pregnant women performing an updated meta-analysis.: Methods: We searched PubMed, Cochrane Central, and SCOPUS from inception to March 2022. Outcomes of interest were incidence of ...

    Abstract Objective: To evaluate the safety and efficacy of COVID-19 vaccines in pregnant women performing an updated meta-analysis.
    Methods: We searched PubMed, Cochrane Central, and SCOPUS from inception to March 2022. Outcomes of interest were incidence of adverse maternal, fetal and neonatal consequences pertaining to safety of the vaccines. Secondarily, we analyzed the number of SARS-CoV-2 infections, hospitalization for COVID-19, and admission to the I.C.U. for COVID-19 assessing the effectiveness of vaccines. Results were pooled using a random effects model.
    Results: Ten observational studies (n=326,499) analyzing pregnant women were included. Our results suggest that COVID-19 vaccination prevents infection (OR: 0.56, 95% CI: 0.47, 0.67; P = <0.00001) and related hospitalizations (OR: 0.50, 95% CI: 0.31, 0.82; P = 0.006) effectively. It was also observed that vaccination does not change adverse outcomes in pregnancy, namely preeclampsia or eclampsia, stroke (four weeks of delivery), meconium-stained amniotic fluid, spontaneous vaginal delivery, operative vaginal delivery, cesarean delivery, postpartum hemorrhage, and blood transfusions. Furthermore, the vaccine was observed to be protective against neonatal COVID-19 I.C.U. admissions (OR: 0.85; 95% CI: 0.81, 0.90; P = <0.00001).
    Conclusion: Our pooled analysis suggests that the COVID-19 vaccination in pregnant women prevents infection effectively and has no adverse outcomes. Future large-scale trials in a randomized fashion are needed to confirm our results.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; COVID-19 Vaccines/adverse effects ; COVID-19/prevention & control ; SARS-CoV-2 ; Delivery, Obstetric ; Cesarean Section
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-08-22
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2022.08.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article ; Online: GeneXpert in stool: Diagnostic yield in Intestinal Tuberculosis.

    Talib, Abu / Bhatty, Shaheen / Mehmood, Khalid / Naim, Huda / Haider, Iftikhar / Lal, Hari / Ali, Gohar / Nashit, Muhammad

    Journal of clinical tuberculosis and other mycobacterial diseases

    2019  Volume 17, Page(s) 100131

    Abstract: Background: Diagnosing intestinal (Luminal) tuberculosis is challenging due to limited yield of diagnostic modalities like CT scan, colonoscopy with blind ileal biopsies. GeneXpert MTB/RIF (Xpert) assays for diagnosing tuberculosis have been performed ... ...

    Abstract Background: Diagnosing intestinal (Luminal) tuberculosis is challenging due to limited yield of diagnostic modalities like CT scan, colonoscopy with blind ileal biopsies. GeneXpert MTB/RIF (Xpert) assays for diagnosing tuberculosis have been performed in the body secretions with excellent results. Its yield in stool is tested in this study.
    Objective: The study aims to evaluate the yield of GeneXpert assay in stool of suspected cases of intestinal tuberculosis.
    Methods: Hundred patients with suspected intestinal tuberculosis underwent routine biochemical tests, radiological investigations, colonoscopy with caecal and blind ileal biopsies for histopathology. Fresh stool samples were collected, processed for DNA extraction, tested using 2:1 ratio of GeneXpert reagent to sample to give positive or negative results for Mycobacterium tuberculosis and Rifampicin resistance.
    Results: Out of hundred participants, 52% were female. Mean age was 28.21 ± 12.13. CT scan and colonoscopy findings suggestive of TB were present in 47% and 43% participants respectively. GeneXpert in stool was positive in 20% cases. Considering mucosal biopsy with histopathology of intestinal specimens as diagnostic of abdominal Tuberculosis, sensitivity and specificity of GeneXpert was 39.1% and 85.7% respectively.
    Conclusion: Stool GeneXpert assay offers an alternative approach to detect intestinal tuberculosis rapidly with good diagnostic accuracy. Although it cannot replace the AFB culture and histopathology but contribute for early diagnosis and management.
    Language English
    Publishing date 2019-11-05
    Publishing country England
    Document type Journal Article
    ISSN 2405-5794
    ISSN (online) 2405-5794
    DOI 10.1016/j.jctube.2019.100131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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