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  1. Article: Proton pump inhibitors use; beware of side-effects.

    Riaz, Sohail / Nasim, Aqeel

    JPMA. The Journal of the Pakistan Medical Association

    2016  Volume 66, Issue 12, Page(s) 1672

    MeSH term(s) Drug-Related Side Effects and Adverse Reactions ; Proton Pump Inhibitors/adverse effects
    Chemical Substances Proton Pump Inhibitors
    Language English
    Publishing date 2016-12-07
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 845: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Evaluation of Availability, Prices, and Affordability of Selected Essential Medicines in Balochistan, Pakistan.

    Bibi, Murad / Haq, Noman Ul / Kareem, Abdul / Ullah, Habib / Baloch, Nizam / Rehman, Gulalai / Nasim, Aqeel

    International journal of public health

    2022  Volume 67, Page(s) 1604375

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Costs and Cost Analysis ; Cross-Sectional Studies ; Drugs, Essential ; Drugs, Generic ; Health Services Accessibility ; Humans ; Pakistan
    Chemical Substances Drugs, Essential ; Drugs, Generic
    Language English
    Publishing date 2022-07-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2274130-6
    ISSN 1661-8564 ; 1661-8556
    ISSN (online) 1661-8564
    ISSN 1661-8556
    DOI 10.3389/ijph.2022.1604375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 843: Show issues Location:
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  3. Article: Public awareness regarding the manufacturer provided information about medicine usage, safety, and adverse drug reactions in Balochistan, Pakistan.

    Khan, Gullab / Haq, Noman / Ahmad, Nafees / Nasim, Aqeel / Javaid, Asma / Saood, Mujhammad / Yasmin, Riffat / Tahir, Maria / Riaz, Sohail / Danish, Zeeshan / Razzaq, Ghulam / Khan, Abdullah / Younis, Muhammad / Rabbani, Tahmina

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1190741

    Abstract: Objectives: ...

    Abstract Objectives:
    Language English
    Publishing date 2023-07-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1190741
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  4. Article ; Online: Evaluation of medication errors in patients with kidney diseases in Quetta, Pakistan.

    Bano, Tahira / Haq, Noman / Nasim, Aqeel / Saood, Muhammad / Tahir, Maria / Yasmin, Riffat / Ahmed, Nisar / Razzaq, Ghulam / Qudos, Shabana / Zarkoon, Abdul Kareem / Shafi, Muhammad

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0289148

    Abstract: Background: Medication errors represent a significant challenge in healthcare, as they can lead to enduring harm for patients and impose substantial financial burdens on the healthcare system. To effectively mitigate medication errors, it is imperative ... ...

    Abstract Background: Medication errors represent a significant challenge in healthcare, as they can lead to enduring harm for patients and impose substantial financial burdens on the healthcare system. To effectively mitigate medication errors, it is imperative to gain a comprehensive understanding of their frequency and the contributing variables. Thus, the primary objective of this study was to evaluate the occurrence of medication errors among patients with kidney diseases in Quetta, Pakistan.
    Methods: The objective of this study was to assess medication errors in patients diagnosed with kidney diseases in Quetta, Pakistan. The research was conducted at the Balochistan Institute of Nephro-Urology Quetta (BINUQ) Hospital, which serves as a tertiary care center specializing in the treatment of kidney diseases. A cross-sectional descriptive study design was employed over a period of six months. The study population consisted of patients admitted to the Nephro-urology wards at BINUQ Hospital during the specified duration. Data collection encompassed various methodologies, including checklist-guided observation, review of prescription order forms, documentation of drug administration, and comprehensive analysis of patient medical records. Descriptive and analytical analyses were conducted using SPSS version 23. Univariate analysis was employed to identify independent variables associated with medication errors, employing a significance level of p<0.01. The multivariate logistic regression analysis incorporated variables that exhibited a significant association with medication errors during the univariate analysis. Only those variables demonstrating a p-value of less than 0.05 at a 95% confidence level were considered significant predictors of medication administration errors within the final multivariate model.
    Results: Among the 274 medication errors identified in the study, documentation errors accounted for 118 cases (12.06%), administration errors for 97 cases (9.91%), prescribing errors for 34 cases (3.47%), and dispensing errors for 25 cases (2.55%). Statistical analysis revealed significant associations (p<0.05) between forgetfulness and duty shift, and medication errors in the documentation process. Similarly, inattention was significantly associated (p<0.05) with both prescribing and dispensing errors. Furthermore, the number of medications received emerged as the most influential factor associated with medication errors. Patients receiving 4-6 medications exhibited an odds ratio of 9.08 (p<0.001) compared to patients receiving 1-3 medications, while patients receiving more than 6 medications had an odds ratio of 4.23 (p<0.001) in relation to patients receiving 1-3 medications.
    Conclusion: In conclusion, this study determined that documentation errors were the most prevalent medication errors observed in patients with kidney disease in Quetta, Pakistan. Forgetfulness and duty shift were associated with documentation errors, whereas inattention was linked to prescribing and dispensing errors. The significant risk factor for medication errors was found to be a high number of prescribed medications. Therefore, strategies aimed at reducing medication errors should prioritize enhancements in documentation practices, alleviating medication burden, and increasing awareness among healthcare providers.
    MeSH term(s) Humans ; Pakistan ; Cross-Sectional Studies ; Medication Errors ; Pharmaceutical Preparations ; Checklist ; Kidney Diseases
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2023-08-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0289148
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  5. Article: Relationship Between Villous Atrophy and tTGA Levels in Dyspeptic Patients: A Case Series.

    Achakzai, Muhammad S / Zarak, Muhammad Samsoor / Arshad, Zara / Sana, Hamaiyal / Tareen, Helmand Khan / Khan, Khushhal / Baloch, Aurangzeb / Kakar, Saliha / Nasim, Aqeel

    Cureus

    2021  Volume 13, Issue 5, Page(s) e15043

    Abstract: Aim The objective of the study was to observe the association of villous atrophy with anti-tissue transglutaminase levels in the identified subjects that met our addressed inclusion criteria. Methods A case series study was conducted among 40 patients ... ...

    Abstract Aim The objective of the study was to observe the association of villous atrophy with anti-tissue transglutaminase levels in the identified subjects that met our addressed inclusion criteria. Methods A case series study was conducted among 40 patients presenting with dyspepsia along with signs and symptoms of celiac disease at the Bolan Medical Complex Hospital, Quetta over a period of five months from 25/5/17 to 25/10/17. The patients were referred to undergo tissue transglutaminase antibody serum test. The positive ones underwent biopsies to assess pathological entities including villous atrophy, blunting (focal or total), crypts, Intestinal layers and the number of Intraepithelial lymphocytes. The results collected were analyzed by using IBM SPSS version 20 (IBM Corp., Armonk, NY). Results There was a weak, negative correlation between tTGA and focal villous blunting (r = -0.345, p = 0.029) showing that high levels of tTGA are associated with lower risk of focal villous blunting. Correlation of tTGA and total villous blunting was a weak positive correlation (r = 0.282, p = 0.07) showing that high levels of tTGA are associated with increased risk of total villous blunting. There was a weak, negative correlation between tTGG and focal villous blunting (r = 0.409, p = 0.009) showing thathigh levels of tTGG are associated with a greater risk of focal villous blunting (p < 0.01) while tTGG and total villous blunting was a weak negative correlation (r = -0.330, p = 0.03) showing that high levels of tTGG are associated with lower risk of total villous blunting. Conclusion The study concludes by providing evidence of the absence of tissue transglutaminase antibodies in patients with histology-proven celiac disease. It implies that serology tests may be negative in some of the patients with typical chronic symptoms. Therefore, in such cases, histopathology may be conclusive in defining the status of celiac disease.
    Language English
    Publishing date 2021-05-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.15043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Association of clinical features of typhoid fever with socioeconomic status in Pakistan.

    Zarak, Muhammad Samsoor / Sana, Hamaiyal / Shah, Muzhgan / Lehri, Shabir / Saghir, Mahekan / Gul, Qandeel / Saood, Muhammad / Nasim, Aqeel / Ul Haq, Noman

    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit

    2021  Volume 27, Issue 11, Page(s) 1078–1083

    Abstract: Background: Typhoid fever is spread by ingestion of contaminated food or water, which is linked to infrastructure; specifically, sewage and sanitation. In developing countries, infrastructure varies according to socioeconomic status (SES). Balochistan ... ...

    Abstract Background: Typhoid fever is spread by ingestion of contaminated food or water, which is linked to infrastructure; specifically, sewage and sanitation. In developing countries, infrastructure varies according to socioeconomic status (SES). Balochistan is the least developed province of Pakistan.
    Aims: To analyse the association between the clinical features of typhoid fever and socioeconomic status.
    Methods: A quantitative, cross-sectional study was conducted in Quetta, Balochistan, Pakistan. Between May and October 2017, 143 patients presented to tertiary care hospitals and private clinics with a complaint of fever lasting ~3 days, along with a clinical history of headache, malaise, diarrhoea or constipation, abdominal pain, dry cough, and anorexia. All patients had a positive blood culture for Salmonella enterica serotype Typhi. Eighteen patients dropped out of the study, leaving 125.
    Results: Seventy (56%) participants had low socioeconomic status (SES), 40 (32%) middle SES and 15 (12%) high SES. The strongest predictors of presenting with typhoid fever were patients' clinical condition when presenting to health facilities, followed by SES. Most respondents had a treatment duration of 1-2 weeks. SES had a high impact on source of drinking water supply.
    Conclusion: The strongest predictor of reporting typhoid fever was the current clinical condition of the patients, followed closely by SES. The incidence of typhoid fever in the low SES patients was almost the same as in the middle and high SES patients. Patients with low SES were more susceptible to contracting typhoid fever due to poor health status and facilities.
    MeSH term(s) Cross-Sectional Studies ; Humans ; Pakistan/epidemiology ; Sanitation ; Social Class ; Typhoid Fever/epidemiology
    Language English
    Publishing date 2021-12-01
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 1291071-5
    ISSN 1687-1634 ; 1020-3397
    ISSN (online) 1687-1634
    ISSN 1020-3397
    DOI 10.26719/emhj.21.054
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4388: Show issues Location:
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  7. Article ; Online: The transgender prostitution: Threat to the rise of AIDS in Pakistan.

    Ul Haq, Noman / Riaz, Sohail / Nasim, Aqeel / Tahir, Maria

    Journal of infection and public health

    2017  Volume 11, Issue 3, Page(s) 448

    MeSH term(s) Acquired Immunodeficiency Syndrome/epidemiology ; Acquired Immunodeficiency Syndrome/transmission ; Condoms ; Female ; HIV Infections/epidemiology ; HIV Infections/transmission ; Humans ; Male ; Mass Screening/statistics & numerical data ; Pakistan/epidemiology ; Sex Work ; Sexual Behavior ; Transgender Persons
    Language English
    Publishing date 2017-08-07
    Publishing country England
    Document type Letter
    ISSN 1876-035X
    ISSN (online) 1876-035X
    DOI 10.1016/j.jiph.2017.07.006
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  8. Article ; Online: Factors and Predictors of Health Related Quality of Life of the General Population of Pakistan.

    Nasim, Aqeel / Haq, Noman Ul / Riaz, Sohail / Khan, Sumaira Irum / Khuda, Fazli / Sipra, Muhammad Faraz / Tariq, Bazil / Tahir, Maria / Saood, Muhammad / Yasmin, Riffat / Manzoor, Kiran / Zeeshan Danish, Muhammad

    Frontiers in public health

    2022  Volume 10, Page(s) 819088

    Abstract: Background and objective: The standards of living, improvement in public health, and medical care in Pakistan are increasing day by day, health-related quality of life (HRQoL) has been increasingly acknowledged in various patient's reported outcomes in ... ...

    Abstract Background and objective: The standards of living, improvement in public health, and medical care in Pakistan are increasing day by day, health-related quality of life (HRQoL) has been increasingly acknowledged in various patient's reported outcomes in Pakistan. However, a large-scale general population-based study on assessing HQRoL in Pakistan was not conducted. Therefore, this study aimed to evaluate HRQoL for the general Pakistani population.
    Material and methods: A cross-sectional study with a population sample (
    Results: Overall, 121 health states were reported in this study. EQ-5D index and EQ-VAS scores were 0.74 ± 0.32 and 0.75 ± 0.25, respectively. The percentage of people responding to any problems increased with age. Males have better health as compared to females in all age groups. All demographics were significantly associated (
    Conclusion: The current study concluded that Age, City, Gender, Education, Occupation, Residence, and House occupancy are significantly affecting HRQOL. The socioeconomically deprived groups and females have inferior health status than more advantaged. The trends detected in high-income nations were usually similar to Pakistan.
    MeSH term(s) Asian People ; Cross-Sectional Studies ; Female ; Health Status ; Humans ; Male ; Pakistan/epidemiology ; Quality of Life
    Language English
    Publishing date 2022-08-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.819088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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