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  1. Book ; Online: Neurorehabilitation: Looking Back and Moving Forward

    Nasios, Grigorios / Messinis, Lambros / Dardiotis, Efthimios / Sgantzos, Markos

    2023  

    Keywords Research & information: general ; Biology, life sciences ; Biochemistry ; Covid-19 ; telerehabilitation ; post-stroke rehabilitation ; virtual reality ; stroke ; percutaneous electric nerve stimulation ; transcutaneous electric nerve stimulation ; adult ; urinary bladder ; overactive ; urinary incontinence ; tibial nerve ; multiple sclerosis ; employment ; patient-reported outcome ; MSWDQ-23 ; validation ; rTMS ; dementia ; Alzheimer's disease ; magnetic stimulation ; non-pharmacological treatments ; refractory temporal seizures ; neurosurgery ; cognitive outcome ; memory ; long-term follow-up ; backward walking ; balance ; cerebral palsy ; mental motor imagery ; neurorehabilitation ; cost-utility ; upper extremity ; EQ-5D ; cognitive exercise therapy ; sensorimotor ; activity of daily living ; Parkinson's disease ; salivation ; clinical features ; non-motor ; motor ; sialorrhea ; drooling ; oxidative stress ; antioxidant defense ; Oxidative Status Index (OSI) ; hydroperoxides ; rehabilitation ; n/a
    Language English
    Size 1 electronic resource (162 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030374745
    ISBN 9783036578606 ; 3036578609
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Detection and Prevention of Mild Cognitive Impairment and Dementia.

    Messinis, Lambros / Nasios, Grigorios / Ioannidis, Panagiotis / Patrikelis, Panayiotis

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 16

    Abstract: Mild cognitive impairment (MCI) is characterized by cognitive deficits alongside essentially preserved competence in activities of daily living [ ... ]. ...

    Abstract Mild cognitive impairment (MCI) is characterized by cognitive deficits alongside essentially preserved competence in activities of daily living [...].
    Language English
    Publishing date 2023-08-08
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11162232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Neurorehabilitation: Looking Back and Moving Forward, 1st Edition.

    Nasios, Grigorios / Messinis, Lambros / Dardiotis, Efthimios / Sgantzos, Markos

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 10

    Abstract: Rehabilitation is "a set of interventions designed to optimize functioning and reduce disability in individuals with health conditions in interaction with their environment", according to the recent report from the World Health Organization (WHO), ... ...

    Abstract Rehabilitation is "a set of interventions designed to optimize functioning and reduce disability in individuals with health conditions in interaction with their environment", according to the recent report from the World Health Organization (WHO), released in January 2023 [...].
    Language English
    Publishing date 2023-05-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11101452
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Undetected language deficits in left or right hemisphere post-stroke patients.

    Martzoukou, Maria / Nousia, Anastasia / Nasios, Grigorios

    Applied neuropsychology. Adult

    2023  , Page(s) 1–9

    Abstract: Previous studies have reported that widely used tests for aphasia identification are unable to detect the subtle language deficits of left hemisphere brain damaged (LHBD) individuals. Similarly, the language disorders of individuals with right hemisphere ...

    Abstract Previous studies have reported that widely used tests for aphasia identification are unable to detect the subtle language deficits of left hemisphere brain damaged (LHBD) individuals. Similarly, the language disorders of individuals with right hemisphere brain damage (RHBD) usually remain undetected, due to the lack of any specialized test for the evaluation of their language processing skills. The aim of the present study was to evaluate the language deficits of 80 individuals suffering from the effects of either a LHBD or RHBD stroke, who were diagnosed as having no aphasia or language deficits based on the application of Boston Diagnostic Aphasia Examination. Their language abilities were examined with the use of the Adults' Language Abilities Test, which explores morpho-syntactic and semantic phenomena of the Greek language in both the comprehension and production modalities. Results revealed that both groups of stroke survivors performed significantly worse compared to the group of healthy participants. Thus, it appears that the latent aphasia of LHBD and the language deficits of RHBD patients are likely to remain undetected and that patients are at risk of not receiving appropriate treatment if their language abilities are not evaluated by an effective and efficient battery of language tests.
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2673736-X
    ISSN 2327-9109 ; 2327-9095
    ISSN (online) 2327-9109
    ISSN 2327-9095
    DOI 10.1080/23279095.2023.2195111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Alzheimer Disease and HIV: Untangling the Gordian Knot.

    Messinis, Lambros / Nasios, Grigorios

    Neurology. Clinical practice

    2021  Volume 11, Issue 5, Page(s) 365–366

    Language English
    Publishing date 2021-11-18
    Publishing country United States
    Document type Editorial
    ZDB-ID 2645818-4
    ISSN 2163-0933 ; 2163-0402
    ISSN (online) 2163-0933
    ISSN 2163-0402
    DOI 10.1212/CPJ.0000000000001102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Illiteracy, Neuropsychological Assessment, and Cognitive Rehabilitation: A Narrative Review.

    Petri, Maria / Messinis, Lambros / Patrikelis, Panayiotis / Nousia, Anastasia / Nasios, Grigorios

    Advances in experimental medicine and biology

    2023  Volume 1425, Page(s) 477–484

    Abstract: Object: Νeuropsychological assessment is particularly important for the accurate discrimination of cognitive abilities and weaknesses of patients in order to determine the appropriate therapeutic intervention. However, the reliability and validity of ... ...

    Abstract Object: Νeuropsychological assessment is particularly important for the accurate discrimination of cognitive abilities and weaknesses of patients in order to determine the appropriate therapeutic intervention. However, the reliability and validity of neuropsychological assessment appears to be influenced by a wide range of factors, including literacy and educational level.
    Aim: This systematic review evaluates neuropsychological tests appropriate for the valid assessment of illiterate individuals and the effectiveness of cognitive rehabilitation programs for illiterate and/or low-educated individuals according to the results of English language studies that have been published in the PubMed/Medline electronic database until August 2022 (no initiation date).
    Results: 49 studies were included for neuropsychological assessment and 4 studies for cognitive rehabilitation. In terms of investigating the validity and reliability of neuropsychological tests for the assessment of healthy illiterate individuals, most studies concluded that for the majority of neuropsychological tests there is a significant difference in performance between healthy illiterate and literate individuals. However, there was consensus among studies that the performance of illiterate subjects was equivalent to the performance of literate subjects on tasks depicting colored and real objects. Regarding cognitive rehabilitation programs, all four studies concluded that they are effective in improving the cognitive functions of illiterate and/or low-literate patients with mild cognitive impairment and/or mild dementia.
    Conclusions: For the assessment of illiterate individuals, it is imperative that neuropsychological tests with high ecological validity (i.e., tests related to activities of daily living) be administered so as not to underestimate their cognitive functioning. At the same time, cognitive enhancement/stimulation programs seem to be effective in this population group; however, this area needs further investigation.
    MeSH term(s) Humans ; Literacy ; Activities of Daily Living ; Reproducibility of Results ; Cognitive Training ; Neuropsychological Tests ; Cognitive Dysfunction/diagnosis
    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 410187-X
    ISSN 0065-2598
    ISSN 0065-2598
    DOI 10.1007/978-3-031-31986-0_46
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Cognitive Rehabilitation for Patients with Schizophrenia: A Narrative Review of Moderating Factors, Strategies, and Outcomes.

    Skokou, Maria / Messinis, Lambros / Nasios, Grigorios / Gourzis, Philippos / Dardiotis, Euthymios

    Advances in experimental medicine and biology

    2023  Volume 1423, Page(s) 193–199

    Abstract: Objective: Antipsychotic drugs constitute the basis of schizophrenia therapy; however, available pharmaceutical agents lack efficacy for treating the cognitive deficits caused by the illness. The aim of the present work is to present current data ... ...

    Abstract Objective: Antipsychotic drugs constitute the basis of schizophrenia therapy; however, available pharmaceutical agents lack efficacy for treating the cognitive deficits caused by the illness. The aim of the present work is to present current data regarding cognitive rehabilitation of schizophrenia, providing information and guidance to health professionals.
    Method: A literature search was conducted in the PubMed and Google Scholar Databases from inception up to 1/9/2022. Relevant articles were explored for factors affecting cognitive function, including genetics, psychopathology, time in the course of the illness, and drug therapy. Characteristics and outcome of cognitive rehabilitation programs are briefly presented.
    Results: A total of 562 relevant articles were retrieved, 39 of which were selected for the review. Factors contributing to a favorable outcome are young age, early phase of disease, symptomatic control of hostility and conceptual disorganization, lack of negative symptoms, management of drug side effects, and cognitive and cortical reserve. Some evidence for a procognitive effect seems to exist for atypical antipsychotics, clozapine, aripiprazole, memantine, modafinil, d-serine, and cycloserine. The Val/Val polymorphism of the COMT gene seems to be associated with worse outcome. Specific remediation strategies include programs such as Cognitive Enhancement Therapy (CET), Cognitive Adaptation Training (CAT), and RehaCom Cognitive Therapy Software, among others, all employing a range of techniques, from paper-and-pencil to computer-assisted, bottom-up, or top-down approaches, and varying neurocognitive targets.
    Conclusion: Cognitive symptoms, closely related to functional impairment, still remain a therapeutic challenge. Cognitive rehabilitation strategies are as yet the only treatment modality offering cognitive improvement to patients who struggle to recover.
    MeSH term(s) Humans ; Schizophrenia/drug therapy ; Schizophrenia/genetics ; Schizophrenia/diagnosis ; Cognitive Training ; Antipsychotic Agents/adverse effects ; Cognition ; Modafinil/pharmacology ; Modafinil/therapeutic use
    Chemical Substances Antipsychotic Agents ; Modafinil (R3UK8X3U3D)
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 410187-X
    ISSN 0065-2598
    ISSN 0065-2598
    DOI 10.1007/978-3-031-31978-5_17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Communication, Feeding and Swallowing Disorders in Neurological Diseases.

    Nasios, Grigorios / Messinis, Lambros / Dardiotis, Efthimios / Kassubek, Jan

    Behavioural neurology

    2022  Volume 2022, Page(s) 9851424

    MeSH term(s) Communication ; Deglutition Disorders ; Humans ; Nervous System Diseases/complications
    Language English
    Publishing date 2022-04-21
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 1001896-7
    ISSN 1875-8584 ; 0953-4180
    ISSN (online) 1875-8584
    ISSN 0953-4180
    DOI 10.1155/2022/9851424
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Pathophysiology and Symptomatology of Drooling in Parkinson's Disease.

    Polychronis, Sotirios / Nasios, Grigorios / Dardiotis, Efthimios / Messinis, Lambros / Pagano, Gennaro

    Healthcare (Basel, Switzerland)

    2022  Volume 10, Issue 3

    Abstract: Drooling can present in patients with Parkinson's disease (PD), and it is manifested as an excessive pooling of saliva inside the oral cavity. Currently, the exact pathophysiological mechanism of drooling in PD is not yet fully explicated. Thus, it ... ...

    Abstract Drooling can present in patients with Parkinson's disease (PD), and it is manifested as an excessive pooling of saliva inside the oral cavity. Currently, the exact pathophysiological mechanism of drooling in PD is not yet fully explicated. Thus, it becomes crucial to understand if some clinical characteristics may emphasize drooling or if they are just concomitant. In PD, excessive drooling has been associated with a higher burden of non-motor symptoms, such as cognitive impairment, sleep problems, autonomic dysfunction, constipation and orthostatic hypotension, and of worse severity of motor fluctuations and bradykinesia. PD patients with excessive drooling also showed a reduction of striatal DAT availability at DaTSCAN imaging. Excessive drooling in patients with Parkinson's cannot be attributed to a single factor but to a mixture of factors, including but not limited to impaired nigrostriatal pathways.
    Language English
    Publishing date 2022-03-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare10030516
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Aging and the Perception of Affective and Linguistic Prosody.

    Martzoukou, Maria / Nasios, Grigorios / Kosmidis, Mary H / Papadopoulou, Despina

    Journal of psycholinguistic research

    2022  Volume 51, Issue 5, Page(s) 1001–1021

    Abstract: Investigations of affective prosodic processing have demonstrated a decline with aging. It is unclear, however, whether this decline affects all or specific emotions. Also, little is known about the ability of syntactic resolution ambiguity with the use ... ...

    Abstract Investigations of affective prosodic processing have demonstrated a decline with aging. It is unclear, however, whether this decline affects all or specific emotions. Also, little is known about the ability of syntactic resolution ambiguity with the use of prosody in aging. Twenty older (age range = 70-75) and 20 younger adults (age range = 20-25) performed an affective (happiness, neutrality, sadness, surprise, fear, and anger) and a linguistic (subject/object ambiguities) prosody task. Relative to young participants, older participants faced difficulty decoding affective prosody, particularly negative emotions, and syntactic prosody, in particular the subject reading condition. A marginally positive correlation was found between the affective and syntactic prosody tasks in the group of older individuals, but no gender differences in either prosodic task. The findings of the affective prosody task are discussed under the prism of the Socioemotional Selectivity Theory, whereas general parsing strategies can account for the preference for the object reading condition.
    MeSH term(s) Adult ; Humans ; Aged ; Young Adult ; Speech Perception ; Linguistics ; Emotions ; Aging/psychology ; Anger
    Language English
    Publishing date 2022-04-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 124517-x
    ISSN 1573-6555 ; 0090-6905
    ISSN (online) 1573-6555
    ISSN 0090-6905
    DOI 10.1007/s10936-022-09875-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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