Article ; Online: Wastewater from healthcare centers in Burkina Faso is a source of ESBL, AmpC-β-lactamase and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae.
2023 Volume 23, Issue 1, Page(s) 351
Abstract: Background: Extended-spectrum β-lactamase (ESBL), plasmid-mediated AmpC-β-lactamase and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae have spread into the environment worldwide posing a potential public health threat. However, the ... ...
Abstract | Background: Extended-spectrum β-lactamase (ESBL), plasmid-mediated AmpC-β-lactamase and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae have spread into the environment worldwide posing a potential public health threat. However, the prevalence data for low- and middle-income countries are still scarce. The aim of this study was to evaluate the presence of ESBL, AmpC-β-lactamase and carbapenemase-producing and multidrug-resistant E. coli and K. pneumoniae in wastewaters from healthcare centers in Burkina Faso. Results: Eighty-four (84) wastewater samples were collected from five healthcare centers and plated on selective ESBL ChromAgar. E. coli and Klebsiella pneumoniae isolates were identified using API20E. ESBL-producing bacteria were detected in 97.6% of the samples and their average concentration per hospital ranged from 1.10 × 10 Conclusions: This study showed that wastewater from healthcare centers constitutes a reservoir of multidrug-resistant bacteria in Burkina Faso, including carbapenemase producers. Untreated healthcare wastewater entering the environment exposes people and animals to infections caused by these multi-resistant bacteria, which are difficult to treat, especially in the resource-poor settings. |
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MeSH term(s) | Humans ; Animals ; Escherichia coli ; Klebsiella pneumoniae ; Wastewater ; Burkina Faso ; Microbial Sensitivity Tests ; beta-Lactamases ; Bacterial Proteins ; Anti-Bacterial Agents/pharmacology ; Escherichia coli Infections/microbiology ; Bacteria ; Carbapenem-Resistant Enterobacteriaceae |
Chemical Substances | carbapenemase (EC 3.5.2.6) ; Wastewater ; beta-Lactamases (EC 3.5.2.6) ; Bacterial Proteins ; Anti-Bacterial Agents |
Language | English |
Publishing date | 2023-11-17 |
Publishing country | England |
Document type | Journal Article ; Research Support, Non-U.S. Gov't |
ZDB-ID | 2041505-9 |
ISSN | 1471-2180 ; 1471-2180 |
ISSN (online) | 1471-2180 |
ISSN | 1471-2180 |
DOI | 10.1186/s12866-023-03108-0 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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