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  1. AU="Natsui, Hiroaki"
  2. AU="Ziv Ben-Ari"
  3. AU="Gönen, Murat"
  4. AU="Soliman, Essam S"
  5. AU="Poenisch, Falk"
  6. AU="Ng C."
  7. AU="Cabaton, Nicolas J"

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  1. Article ; Online: Effect of acute moderate-intensity cycling on cfDNA levels considering menstrual cycle phases.

    Sawai, Akemi / Shida, Takashi / Hoshikawa, Yoshihiro / Hatanaka, Sho / Ueda, Mashiro / Kato, Yuri / Tokinoya, Katsuyuki / Natsui, Hiroaki / Kawakami, Yasushi / Takekoshi, Kazuhiro

    Frontiers in sports and active living

    2024  Volume 6, Page(s) 1322295

    Abstract: Introduction: We aimed to determine the effects of exercise on cell-free DNA (cfDNA) levels and concentration changes during the menstrual cycle in participants with regular menstrual cycles and no exercise habits.: Methods: Eleven sedentary female ... ...

    Abstract Introduction: We aimed to determine the effects of exercise on cell-free DNA (cfDNA) levels and concentration changes during the menstrual cycle in participants with regular menstrual cycles and no exercise habits.
    Methods: Eleven sedentary female students with regular menstrual cycles and ovulation performed bicycle exercises at 60% VO
    Results: Based on the concentration of ovarian hormones, seven individuals were finally analyzed. No significant phase difference was observed in cfDNA across all time points. cfDNA (menstrual phase:
    Discussion: The results indicate that while resting cfDNA levels are unlikely to be affected by a woman's menstrual cycle, the increase in cfDNA after exercise is higher in the ovulatory phase (when only E2 increases) and lower in the luteal phase (when E2 and P4 increase with exercise) compared to that in the menstrual phase (when E2 and P4 are in low levels), suggesting the contribution of increased ovarian hormone levels after exercise.
    Language English
    Publishing date 2024-01-29
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2024.1322295
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparisons of the Prevalence, Severity, and Risk Factors of Dysmenorrhea between Japanese Female Athletes and Non-Athletes in Universities.

    Momma, Reiko / Nakata, Yoshio / Sawai, Akemi / Takeda, Maho / Natsui, Hiroaki / Mukai, Naoki / Watanabe, Koichi

    International journal of environmental research and public health

    2021  Volume 19, Issue 1

    Abstract: This study aimed to investigate the difference in the prevalence, severity, and risk factors of dysmenorrhea between Japanese female athletes and non-athletes in universities. The participants were 18 to 30 years old with no history of a previous ... ...

    Abstract This study aimed to investigate the difference in the prevalence, severity, and risk factors of dysmenorrhea between Japanese female athletes and non-athletes in universities. The participants were 18 to 30 years old with no history of a previous pregnancy and/or childbirth. After application of the exclusion criteria, the cohort comprised 605 athletes and 295 non-athletes. An anonymous questionnaire, which included self-reported information on age, height, weight, age at menarche, menstrual cycle days, menstrual duration, dysmenorrhea severity, sleeping hours, dietary habits, exercise habits, training hours, and competition level was administered. Compared with athletes, non-athletes had a higher prevalence of dysmenorrhea (85.6% in athletes, 90.5% in non-athletes,
    MeSH term(s) Adolescent ; Adult ; Athletes ; Dysmenorrhea/epidemiology ; Female ; Humans ; Japan/epidemiology ; Pregnancy ; Prevalence ; Risk Factors ; Surveys and Questionnaires ; Universities ; Young Adult
    Language English
    Publishing date 2021-12-21
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19010052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Anterior cruciate ligament injury: Identifying information sources and risk factor awareness among the general population.

    Nagano, Yasuharu / Yako-Suketomo, Hiroko / Natsui, Hiroaki

    PloS one

    2018  Volume 13, Issue 1, Page(s) e0190397

    Abstract: Introduction: Raising awareness on a disorder is important for its prevention and for promoting public health. However, for sports injuries like the anterior cruciate ligament (ACL) injury no studies have investigated the awareness on risk factors for ... ...

    Abstract Introduction: Raising awareness on a disorder is important for its prevention and for promoting public health. However, for sports injuries like the anterior cruciate ligament (ACL) injury no studies have investigated the awareness on risk factors for injury and possible preventative measures in the general population. The sources of information among the population are also unclear. The purpose of the present study was to identify these aspects of public awareness about the ACL injury.
    Materials and methods: A questionnaire was randomly distributed among the general population registered with a web based questionnaire supplier, to recruit 900 participants who were aware about the ACL injury. The questionnaire consisted of two parts: Question 1 asked them about their sources of information regarding the ACL injury; Question 2 asked them about the risk factors for ACL injury. Multivariate logistic regression was used to determine the information sources that provide a good understanding of the risk factors.
    Results and discussion: The leading source of information for ACL injury was television (57.0%). However, the results of logistic regression analysis revealed that television was not an effective medium to create awareness about the risk factors, among the general population. Instead "Lecture by a coach", "Classroom session on Health", and "Newspaper" were significantly more effective in creating a good awareness of the risk factors (p < 0.001).
    MeSH term(s) Adult ; Anterior Cruciate Ligament Injuries/epidemiology ; Awareness ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Risk Factors ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2018-01-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0190397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Risk of female athlete triad development in Japanese collegiate athletes is related to sport type and competitive level.

    Sawai, Akemi / Mathis, Bryan J / Natsui, Hiroaki / Zaboronok, Alexander / Mitsuhashi, Risa / Warashina, Yuki / Mesaki, Noboru / Shiraki, Hitoshi / Watanabe, Koichi

    International journal of women's health

    2018  Volume 10, Page(s) 671–687

    Abstract: Introduction: Menstrual dysfunction, musculoskeletal injury, and poor nutrition combine to form the female athlete triad (FAT), which results in serious health consequences for affected athletes. To this point, the risk factors of this phenomenon have ... ...

    Abstract Introduction: Menstrual dysfunction, musculoskeletal injury, and poor nutrition combine to form the female athlete triad (FAT), which results in serious health consequences for affected athletes. To this point, the risk factors of this phenomenon have not been fully explored in Japanese female college athletes. Additionally, the effect of competitive level on FAT risk factors has also not been reported. Therefore, we aimed to examine FAT risk factors in Japanese female athletes of various sports as well as examine the impact of competitive level on FAT.
    Methods: A Japanese-language survey was completed by 531 athletes and 20 nonathletes at two Japanese universities and answers with regard to menstrual status, musculoskeletal injury, nutrition, and other variables were analyzed based on classification of the sports into nine distinct groups based on activity type. Sport intensity, training volume, and competitive levels were used to further classify each sport. One-way ANOVA and the Bonferroni post hoc test using SPSS were carried out to analyze significance for relationships between sport intensity and FAT risk factors. Additionally, the relationship between competitive level and FAT risk factors was analyzed by ANOVA and Bonferroni post hoc tests.
    Results: Sport intensity was positively correlated with a delay in menarche as well as dysmenorrhea and poor nutrition while musculoskeletal injury was correlated with repetitive, high-training volume sports. Lower competitive levels increased dysmenorrhea but did not impact injury status or nutrition.
    Conclusion: Sport intensity and training volume, but not competitive level, are the critical factors affecting FAT risk in Japanese female college athletes.
    Language English
    Publishing date 2018-10-30
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2508161-5
    ISSN 1179-1411
    ISSN 1179-1411
    DOI 10.2147/IJWH.S175446
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Effects of cryotherapy after contusion using real-time intravital microscopy.

    Lee, Hoseong / Natsui, Hiroaki / Akimoto, Takayuki / Yanagi, Kennichi / Ohshima, Norio / Kono, Ichiro

    Medicine and science in sports and exercise

    2005  Volume 37, Issue 7, Page(s) 1093–1098

    Abstract: Purpose: To examine effects of local tissue cooling on contusion-induced microvascular hemodynamics and leukocytes behavior using real-time intravital microscopy.: Methods: Male Wistar rats (N = 21, 130-150 g) were randomly assigned to intensive ... ...

    Abstract Purpose: To examine effects of local tissue cooling on contusion-induced microvascular hemodynamics and leukocytes behavior using real-time intravital microscopy.
    Methods: Male Wistar rats (N = 21, 130-150 g) were randomly assigned to intensive cooling group (3 degrees C, N = 7), a moderate cooling group (27 degrees C, N = 7), or control group (37 degrees C, N = 7). Contusion was induced by dropping a plastic ball on exposed cremaster muscle. After 5 min, the cremaster muscle was superfused with a saline solution for 10 min at controlled temperature of either 3 degrees C (cooling), 27 degrees C (moderate cooling), or 37 degrees C (control). Microvascular hemodynamics (vessel internal diameter, blood flow rate and erythrocyte velocity) and leukocyte behavior (rolling and adhesion) were measured from recorded videotapes in the same venules before and after contusion, and after cooling.
    Results: Cooling-induced vasoconstriction was marked at 3 degrees C and moderate at 27 degrees C compared with that at 37 degrees C. Blood flow rate and erythrocyte velocity were markedly lower at 3 degrees C compared to 37 degrees C. At 27 degrees C, erythrocyte velocity was higher than that at 37 degrees C, but blood flow rate was maintained at a level similar to that at 37 degrees C. The number of rolling and adhering leukocytes at 3 degrees C and 27 degrees C were significantly less than at 37 degrees C.
    Conclusion: Our results suggest that local tissue cooling, similar to cryotherapy, improves edema and inflammatory reaction, and may be useful for reducing inflammatory response without inhibiting blood flow after contusion.
    MeSH term(s) Animals ; Blood Flow Velocity ; Contusions/blood ; Contusions/pathology ; Contusions/therapy ; Cryotherapy/instrumentation ; Erythrocytes/physiology ; Japan ; Leukocytes/physiology ; Male ; Microscopy/methods ; Muscle, Skeletal/blood supply ; Rats ; Rats, Wistar
    Language English
    Publishing date 2005-04-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603994-7
    ISSN 1530-0315 ; 0195-9131 ; 0025-7990
    ISSN (online) 1530-0315
    ISSN 0195-9131 ; 0025-7990
    DOI 10.1249/01.mss.0000169611.21671.2e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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