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  1. Article: Unveiling the Role of IGF-I in Fertility: Effect of Long-Acting Bovine Somatotropin (bST) on Terminal Follicular Development and Fertility during an Annual Reproductive Cycle in Sheep.

    Cox, José Francisco / Carrasco, Albert / Navarrete, Felipe / Allende, Rodrigo / Saravia, Fernando / Dorado, Jesús

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 7

    Abstract: The study aimed to assess the effect of long-acting bST treatment, in a dose that only increases IGF-I plasma concentrations, on ovarian and fertility markers of estrous synchronized ewes that were fed to keep their bodyweight. Three experiments were ... ...

    Abstract The study aimed to assess the effect of long-acting bST treatment, in a dose that only increases IGF-I plasma concentrations, on ovarian and fertility markers of estrous synchronized ewes that were fed to keep their bodyweight. Three experiments were designed to evaluate this effect: in Experiment 1, 18 ewes were distributed in groups (bST 0, 30, 50 mg) to measure plasma IGF-I and insulin for 15 days; in Experiment 2, 92 ewes (5 replicates) in two groups (0 and 30 mg bST) were synchronized using a 6-day progesterone protocol during the breeding season to assess the effect of bST on follicular and luteal performances, estrous and ovulation, and fertility after mating. In Experiment 3, 50 ewes (3 replicates) were used to repeat the study before but during anestrus. Results indicate that 50 mg bST increased IGF-I and insulin plasma concentrations, but 30 mg bST only increased IGF-I concentrations; and that only during the breeding season did 30 mg bST increase the number of lambs born and the reproductive success of ovulatory-sized follicles compared to controls. This occurred without it affecting any other reproductive marker. In conclusion, 30 mg bST treatment may improve oocyte competence for fertility during the breeding season.
    Language English
    Publishing date 2024-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14071097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Subovulatory Dose of Human Chorionic Gonadotropin (hCG) May Sustain Terminal Follicle Development and Reproductive Efficiency during Anestrus in Sheep.

    Cox, José Francisco / Carrasco, Albert / Navarrete, Felipe / Bocic, Antonio / Saravia, Fernando / Dorado, Jesús

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 7

    Abstract: The study tested the hypothesis that a single administration of hCG supports the LH-dependent phase of terminal follicular development in synchronized sheep during anestrus, using eCG as a functional reference. Using a clinical approach, four experiments ...

    Abstract The study tested the hypothesis that a single administration of hCG supports the LH-dependent phase of terminal follicular development in synchronized sheep during anestrus, using eCG as a functional reference. Using a clinical approach, four experiments were designed to achieve the following: (1) Identify the inhibitory influence of anestrus on reproduction efficiency; (2) Assess the potential of hCG to keep functional blood concentrations after a single dose; (3) Characterize the effect of different doses of hCG on reproductive functional markers; (4) To compare the ability of hCG to that of eCG to support follicular development and fertility based on the same markers. The results showed that anestrus seems to affect follicular and luteal function under LH dependency as FSH-dependent markers are not compromised; hCG maintains higher blood concentrations than controls for at least 48 h; hCG improves follicular development and ovulatory rates compared to controls and at standards comparable to a breeding season; and ewes treated with hCG exhibit similar performance to those treated with eCG. Our results conclude that hCG can be used to support follicular function during anestrus in sheep, aiming to perfect its regulation in assisted reproduction.
    Language English
    Publishing date 2024-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14071096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Mediating Role of the Muscle Quality Index in the Relation of Screen Time and Abdominal Obesity with Health-Related Quality of Life in Chilean Schoolchildren.

    Delgado-Floody, Pedro / Gómez-López, Manuel / Caamaño-Navarrete, Felipe / Valdés-Badilla, Pablo / Jerez-Mayorga, Daniel

    Nutrients

    2023  Volume 15, Issue 3

    Abstract: Screen time (ST) and abdominal obesity have a negative effect on health-related quality of life (HRQoL). However, there is little information regarding the mediating role of the muscle quality index (MQI) in these relationships. The aim of the present ... ...

    Abstract Screen time (ST) and abdominal obesity have a negative effect on health-related quality of life (HRQoL). However, there is little information regarding the mediating role of the muscle quality index (MQI) in these relationships. The aim of the present study was to investigate the association between HRQoL, physical status (i.e., anthropometrics and fitness), lifestyle (i.e., ST and physical activity), and the MQI, and then to determine the potential mediating role of the MQI in the relation of ST and abdominal obesity with HRQoL in Chilean schoolchildren. The cross-sectional study included 750 schoolchildren (girls,
    MeSH term(s) Male ; Female ; Humans ; Child ; Adolescent ; Quality of Life ; Obesity, Abdominal/epidemiology ; Chile/epidemiology ; Cross-Sectional Studies ; Screen Time ; Obesity ; Muscles ; Body Mass Index
    Language English
    Publishing date 2023-01-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15030714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Muscle Quality Index in Morbidly Obesity Patients Related to Metabolic Syndrome Markers and Cardiorespiratory Fitness.

    Caamaño-Navarrete, Felipe / Jerez-Mayorga, Daniel / Alvarez, Cristian / Del-Cuerpo, Indya / Cresp-Barría, Mauricio / Delgado-Floody, Pedro

    Nutrients

    2023  Volume 15, Issue 11

    Abstract: Background: Muscle quality index (MQI) is an emerging health indicator obtained by dividing handgrip strength by body mass index (BMI) that needs to be studied in morbidly obese patients (defined by BMI ≥ 35 kg/m: Objective: To determine the ... ...

    Abstract Background: Muscle quality index (MQI) is an emerging health indicator obtained by dividing handgrip strength by body mass index (BMI) that needs to be studied in morbidly obese patients (defined by BMI ≥ 35 kg/m
    Objective: To determine the association between MQI, metabolic syndrome (MetS) markers, and cardiorespiratory fitness (CRF), and as a second objective to determine the potential mediation role of MQI in the relationship between abdominal obesity and systolic blood pressure (SBP) in this sample.
    Methods: This cross-sectional study included 86 severely/morbidly obese patients (age = 41.1 ± 11.9 y, nine men). MQI, metabolic syndrome markers, CRF, and anthropometric parameters were measured. Two groups were developed according to MQI; High-MQI (
    Results: The Low-MQI group reported higher abdominal obesity (High-MQI: 0.7 ± 0.1 vs. Low-MQI: 0.8 ± 0.1 WC/height;
    Conclusions: MQI in morbidly obesity patients reported an inverse association with MetS markers and a positive association with CRF (VO2
    MeSH term(s) Male ; Humans ; Adult ; Middle Aged ; Cardiorespiratory Fitness ; Metabolic Syndrome ; Physical Fitness/physiology ; Obesity, Abdominal/complications ; Obesity, Morbid/complications ; Hand Strength ; Cross-Sectional Studies ; Body Mass Index ; Muscles
    Language English
    Publishing date 2023-05-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15112458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Geographic Differences in Semen Quality among a Cohort of American Men Using Mail-in Sperm Testing Kits.

    Aznavour, Yana / Navarrete, Felipe / Badreddine, Jad / Simon, Paul H G / Gowda, Vrushab / Rhodes, Stephen / Ghayda, Ramy Abou

    The world journal of men's health

    2023  Volume 41, Issue 4, Page(s) 920–927

    Abstract: Purpose: To evaluate the relationship between regional geography and sperm parameters in a cohort of American men using at-home mail-in semen collection kits with no previous self-reported history of male factor infertility.: Materials and methods: ... ...

    Abstract Purpose: To evaluate the relationship between regional geography and sperm parameters in a cohort of American men using at-home mail-in semen collection kits with no previous self-reported history of male factor infertility.
    Materials and methods: In this study, 5,822 men from six different regions of the United States (Northeast, Southeast, Midwest, West, Pacific, and Southwest) who self-requested semen analysis between 2019 and 2021 were enrolled.
    Results: Across the entire cohort, the mean sperm concentration was 43.79±55.43 ×10
    Conclusions: This study provides the most comprehensive and up-to-date report on semen parameter variability among a cohort of men living in six different regions of the continental USA. This study will pave the way into a deeper discussion of the interplay between geography, social determinants of fertility care and semen quality.
    Language English
    Publishing date 2023-01-19
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2719786-4
    ISSN 2287-4690 ; 2287-4208
    ISSN (online) 2287-4690
    ISSN 2287-4208
    DOI 10.5534/wjmh.220184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Variability of Semen Parameters With Sexual Abstinence Using Mail-in Sperm Testing Is Similar to That Seen With Traditional In-Office Semen Analysis.

    Badreddine, Jad / Rhodes, Stephen / Sellke, Nicholas / Navarrete, Felipe / Keller, Stephanie / Gowda, Vrushab / Simon, Paul H G / Abou Ghayda, Ramy

    American journal of men's health

    2023  Volume 17, Issue 5, Page(s) 15579883231197910

    Abstract: The impact of ejaculatory abstinence on semen parameters using in-office semen analyses has been well-established; however, their variability has not been evaluated in men using mail-in semen analysis kits. Our study aims to describe how the sperm ... ...

    Abstract The impact of ejaculatory abstinence on semen parameters using in-office semen analyses has been well-established; however, their variability has not been evaluated in men using mail-in semen analysis kits. Our study aims to describe how the sperm parameters using mail-in semen analysis tests change with abstinence and validate their equivalence to those seen with in-office semen analysis tests. We retrospectively reviewed the semen analysis results of men using mail-in semen analysis tests provided by Give Legacy, Inc (Legacy) facilities from 2019 to 2021. We collected their demographic information, abstinence duration, and semen parameters (conventional and kinematic) from their records. Semen samples were categorized as normozoospermic and oligozoospermic based on concentration. The shape of the relationship between abstinence duration and semen parameters was assessed via generalized additive models. We have collected 3,469 unique samples provided by 2,609 (75%) normozoospermic men and 860 (25%) oligozoospermic from all over the United States. In normozoospermic men, longer periods of sexual abstinence were linked to higher levels of sperm concentration, total sperm count, and total motile sperm. However, there was a decline in both total and progressive motility. Conversely, in oligozoospermic men, extended periods of abstinence led to a rapid decline in total motile sperm, as well as total and progressive motility. There was no significant correlation observed between sexual abstinence and variations in sperm morphology. Our study shows that variability of sperm parameters with abstinence, as measured through mail-in semen analysis tests, is comparable to the patterns observed with conventional in-office sperm testing.
    MeSH term(s) Male ; Humans ; Semen ; Sexual Abstinence ; Retrospective Studies ; Postal Service ; Sperm Motility ; Semen Analysis ; Spermatozoa
    Language English
    Publishing date 2023-09-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2275106-3
    ISSN 1557-9891 ; 1557-9883
    ISSN (online) 1557-9891
    ISSN 1557-9883
    DOI 10.1177/15579883231197910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Negative Physical Self-Concept Is Associated to Low Cardiorespiratory Fitness, Negative Lifestyle and Poor Mental Health in Chilean Schoolchildren

    Delgado-Floody, Pedro / Soto-García, Diego / Caamaño-Navarrete, Felipe / Carter-Thuillier, Bastián / Guzmán-Guzmán, Iris Paola

    Nutrients. 2022 July 05, v. 14, no. 13

    2022  

    Abstract: Background: Evidence suggests that physical self-concept (PSC) is linked to well-being in children and adolescents. Objective: The objective was to investigate the association of PSC with mental health (i.e., depression and body image), physical status ( ... ...

    Abstract Background: Evidence suggests that physical self-concept (PSC) is linked to well-being in children and adolescents. Objective: The objective was to investigate the association of PSC with mental health (i.e., depression and body image), physical status (i.e., fitness and weight status) and lifestyle (physical activity (PA) patterns and nutritional level) in Chilean schoolchildren. Methods: A total of 617 schoolchildren (n = 271 girls and n = 346 boys) aged 10–14 years participated in this study. Self-concept, depression and body image dissatisfaction were determined by questionnaires. Physical fitness, PA, screen time (ST), Mediterranean diet (MD) adherence and anthropometric parameters were also included. Results: Poor PSC was linked to bad cardiorespiratory fitness (CRF) (<42 VO₂ₘₐₓ) (OR 1.64; 95%CI 1.12–2.34; p = 0.01), severe body image dissatisfaction (OR 2.51, 95%CI 0.99–6.35; p = 0.05), ST of more than two hours a day (OR 2.1; 95%CI 1.41–3.12; p < 0.001), PA after school of no more than two hours per week (OR 1.52; 95%CI 1.08–2.13; p = 0.015) and depression (OR 1.80; 95%CI 1.1–2.92; p = 0.017). High nutritional level showed an association with general PSC and general self-concept (p < 0.05). Absence of body image dissatisfaction was related to general self-concept (p < 0.01) and physical condition dimensions (p < 0.05). Conclusions: PSC is associated with CRF, PA after school, ST and nutritional level. According to mental health variables, poor PSC is related to depression in Chilean schoolchildren. Therefore, promoting a healthy lifestyle among children should be a target of community- and school-based interventions to promote PSC.
    Keywords Mediterranean diet ; body dissatisfaction ; cardiorespiratory fitness ; lifestyle ; mental health ; physical activity ; self-perception
    Language English
    Dates of publication 2022-0705
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2518386-2
    ISSN 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14132771
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Speed and throwing the ball are related to jump capacity and skeletal muscle mass in university basketball players.

    Caamaño-Navarrete, Felipe / Delgado-Floody, Pedro / Martinez-Salazar, Cristian / Jerez-Mayorga, Daniel

    The Journal of sports medicine and physical fitness

    2021  Volume 61, Issue 6, Page(s) 771–778

    Abstract: Background: Speed and throw ball in basketball players are determinant skills for basketball performance. The purpose of this study was to determinate the relationship between speed and throw the ball with jump capacity and body composition in ... ...

    Abstract Background: Speed and throw ball in basketball players are determinant skills for basketball performance. The purpose of this study was to determinate the relationship between speed and throw the ball with jump capacity and body composition in university basketball players.
    Methods: A comparative descriptive study with transversal design and a quantitative approach was performed. Seventeen male University basketball players (age = 23.60±3.45 years, height = 180.41±7.99 cm and Body Mass = 86.48±20.07 Kg) completed the following test: throwing the ball (m/s), handgrip strength (kg), speed 5-20 m (i.e., with and without the ball), jumping and reactive strength. Likewise, anthropometric variables and body composition were evaluated.
    Results: A very high correlation was found between the throw ball and the skeletal muscle mass (r=0.810, P<0.001) dominant handgrip strength (r=0.709, P<0.001) and non-dominant handgrip strength (r=0.610, P<0.01). The throw ball reported association with skeletal muscle mass (r2=0.67, P<0.001, 67% of the variance). Significant differences were found in speed with and without the ball at 10 m (P=0.003, ES=-0.854), 15 m (P=<001, ES=-1.548) and 20 m (P=<001, ES=-1.644). The speed of displacement without ball correlated high with the countermovement jump (CMJ) (r=-0.530, P≤0.05) Abalakov (r=-0.586, P≤0.05) and Drop Jump (DJ) (r=-0.685, P≤0.01) in the first 5 m.
    Conclusions: The speed and throwing of the ball are associated with jumping capacity and skeletal muscle mass. Therefore, it is necessary to work these capacities in the university basketball player to improve performance.
    MeSH term(s) Adult ; Athletic Performance/physiology ; Basketball/physiology ; Body Composition ; Hand Strength/physiology ; Humans ; Male ; Muscle, Skeletal/physiology ; Universities ; Young Adult
    Language English
    Publishing date 2021-06-10
    Publishing country Italy
    Document type Comparative Study ; Journal Article
    ZDB-ID 410823-1
    ISSN 1827-1928 ; 0022-4707
    ISSN (online) 1827-1928
    ISSN 0022-4707
    DOI 10.23736/S0022-4707.20.11411-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Association between Creativity and Memory with Cardiorespiratory Fitness and Lifestyle among Chilean Schoolchildren

    Caamaño-Navarrete, Felipe / Latorre-Román, Pedro Á / Párraga-Montilla, Juan A. / Álvarez, Cristian / Delgado-Floody, Pedro

    Nutrients. 2021 May 25, v. 13, no. 6

    2021  

    Abstract: The objective was to investigate the association between creativity and memory with cardiorespiratory fitness (CRF; i.e., CFR classification and V˙O₂ₘₐₓ); lifestyle parameters (i.e., physical activity (PA), sleep duration, screen time (ST), and food ... ...

    Abstract The objective was to investigate the association between creativity and memory with cardiorespiratory fitness (CRF; i.e., CFR classification and V˙O₂ₘₐₓ); lifestyle parameters (i.e., physical activity (PA), sleep duration, screen time (ST), and food habits); and anthropometric measures (i.e., body mass index (BMI), waist circumference (WC)) among Chilean schoolchildren. A total of 248 schoolchildren (137 boys, 111 girls, 11.80 ± 1.17 and 11.58 ± 1.09 years, respectively) participated in the cross-sectional study. Creativity, memory, concentration, and selective attention and lifestyle (PA, ST, sleep duration, and Mediterranean diet (MD) adherence) were measured using a standard questionnaire. CRF (measured by the 20 m shuttle run test and expressed as maximum oxygen consumption (V˙O₂ₘₐₓ) and anthropometric measures (BMI and WC) were also included. Creativity showed a positive association with V˙O₂ₘₐₓ (mL/kg/min) (β; 0.209, 95% CI; 0.02–0.40, p = p < 0.05) and MD Adherence (score) (β; 0.206, 95% CI; 0.01; 0.74, p = p < 0.05). Long-term memory reported a positive association with CRF (β; 1.076, 95% CI; 0.02–2.13, p = p < 0.05). An increase in CRF levels, together with healthy food habits and normal nutritional status, should be a target for community- and school-based interventions to promote cognitive development in creativity and memory among schoolchildren.
    Keywords Mediterranean diet ; body mass index ; cardiorespiratory fitness ; cognitive development ; cross-sectional studies ; healthy diet ; lifestyle ; memory ; nutritional status ; oxygen consumption ; physical activity ; questionnaires ; sleep ; waist circumference
    Language English
    Dates of publication 2021-0525
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2518386-2
    ISSN 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu13061799
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Semen parameter variability among users of at-home sperm testing kits.

    Aznavour, Yana / Navarrete, Felipe / Badreddine, Jad / Simon, Paul H G / Gowda, Vrushab / Rhodes, Stephen / Abou Ghayda, Ramy

    BMC urology

    2022  Volume 22, Issue 1, Page(s) 184

    Abstract: Background: Despite the generally accepted World Health Organization guidelines on semen analysis, an individual's results can display significant variation when performed across time or in different laboratories. Semen parameters are in fact highly ... ...

    Abstract Background: Despite the generally accepted World Health Organization guidelines on semen analysis, an individual's results can display significant variation when performed across time or in different laboratories. Semen parameters are in fact highly variable measures that can differ significantly between various analyses. Numerous researchers have discovered a wide range of semen parameters within each individual male, but only a few studies included the analysis of semen parameters variability in patients with infertility. The aim of this study was to evaluate the inter- and intra-individual variability of semen parameters in men of reproductive age with normozoospermia and those with oligozoospermia.
    Methods: Five hundred and thirteen who provided ≥ 2 semen samples (798 samples in total) using an at-home mail-in kit over a period of about 2 years were enrolled in the study. Semen samples collection using Give Legacy at-home mail-in semen collection kit; semen analysis at a CLIA-certified laboratory.
    Results: The degree of intra-subject variation across all semen parameters was lower in men with normozoospermia compared to men with oligozoospermia. Men with normozoospermia furthermore demonstrated a level of intra-subject variation that was lower than inter-subject variation across all measured parameters. No association was observed between intra-subject coefficients of variation in any of the semen parameters, including sperm concentration, sperm count, motile sperm count, total motility, progressive motility, the percentage of sperm with normal morphology, and the age, duration of abstinence, and BMI of the men.
    Conclusion: The results of this observational study confirm the significant variability in semen parameters in men with normozoospermia and oligozoospermia, as measured from at-home semen collection kit samples. This further underscore the importance of securing multiple samples for analysis to provide a robust assessment of male fertility.
    MeSH term(s) Male ; Humans ; Semen ; Sperm Motility ; Oligospermia/diagnosis ; Sperm Count ; Spermatozoa ; Infertility, Male/diagnosis
    Language English
    Publishing date 2022-11-15
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2059857-9
    ISSN 1471-2490 ; 1471-2490
    ISSN (online) 1471-2490
    ISSN 1471-2490
    DOI 10.1186/s12894-022-01134-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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