LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Back to previous search Search history
Advanced search

Your last searches

  1. AU="Navarro-Amuedo, María Dolores"
  2. AU="Michellier, C"
  3. AU="Stephan Immenschuh"
  4. AU="Phillips, Sabrina"
  5. AU="Fadilah Fadilah"
  6. AU="Kira, Kei"
  7. AU="Modesto, Irene"
  8. AU="Bertha Rita Castillo Edua"
  9. AU="Hannah Danbury"
  10. AU="Elramly, Mohamed"
  11. AU="Louella, Michael"
  12. AU=Bolton Judy L
  13. AU="Riederer, Cordula"
  14. AU="Bao, Qi"
  15. AU="Tsang, Stephen H"
  16. AU="Isaranuwatchai, Wanrudee" AU="Isaranuwatchai, Wanrudee"
  17. AU="Goldring, Mary B"
  18. AU="Durrington, Charlotte"
  19. AU="Metka, M."
  20. AU="González Villarroel, Paula"
  21. AU="Gakuya, F."
  22. AU="Belloni-Fortina, Anna"
  23. AU="Teufel, Frank"

Search results

Result 1 - 9 of total 9

Search options

  1. Article: Clinical Outcomes of an Innovative Cefazolin Delivery Program for MSSA Infections in OPAT.

    Herrera-Hidalgo, Laura / Luque-Márquez, Rafael / de Alarcon, Aristides / Guisado-Gil, Ana Belén / Gutierrez-Gutierrez, Belen / Navarro-Amuedo, Maria Dolores / Praena-Segovia, Julia / Carmona-Caballero, Juan Manuel / Fraile-Ramos, Elena / Gutierrez-Valencia, Alicia / Lopez-Cortes, Luis Eduardo / Gil-Navarro, Maria Victoria

    Journal of clinical medicine

    2022  Volume 11, Issue 6

    Abstract: Cefazolin is a recommended treatment for methicillin-susceptible Staphylococcus aureus (MSSA) infections that has been successfully used in outpatient parenteral antibiotic therapy (OPAT) programs. The aim of this study was to assess the clinical ... ...

    Abstract Cefazolin is a recommended treatment for methicillin-susceptible Staphylococcus aureus (MSSA) infections that has been successfully used in outpatient parenteral antibiotic therapy (OPAT) programs. The aim of this study was to assess the clinical outcomes of cefazolin delivered each day (Group 24) vs. every two days (Group 48) for MSSA infections in OPAT programs. It was a prospective observational study with retrospective analysis of a cohort of MSSA infections attended in OPAT. The primary outcome was treatment success, defined as completing the antimicrobial regimen without death, treatment discontinuation, or readmission during treatment and follow-up. A univariate and multivariate logistic regression model was built. A two-sided p < 0.05 was considered statistically significant. Of the 149 MSSA infections treated with cefazolin 2 g/8 h in OPATs, 94 and 55 patients were included in the delivery Group 24 and Group 48, respectively. Treatment failure and unplanned readmission rates were similar in both groups (11.7% vs. 7.3% p = 0.752 and 8.5% vs. 5.5% p = 0.491). There was a significant increase in vascular access complications in Group 24 (33.0%) with respect to Group 48 (7.3%) (p < 0.001). Treating uncomplicated MSSA infection with cefazolin home-delivered every two days through an OPAT program is not associated with an increased risk of treatment failure and entails a significant reduction in resource consumption compared to daily delivery.
    Language English
    Publishing date 2022-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11061551
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: A quick prediction tool for unfavourable outcome in COVID-19 inpatients: Development and internal validation.

    Salto-Alejandre, Sonsoles / Roca-Oporto, Cristina / Martín-Gutiérrez, Guillermo / Avilés, María Dolores / Gómez-González, Carmen / Navarro-Amuedo, María Dolores / Praena-Segovia, Julia / Molina, José / Paniagua-García, María / García-Delgado, Horacio / Domínguez-Petit, Antonio / Pachón, Jerónimo / Cisneros, José Miguel

    The Journal of infection

    2020  Volume 82, Issue 2, Page(s) e11–e15

    MeSH term(s) COVID-19 ; Cohort Studies ; Critical Care ; Humans ; Inpatients ; Risk Factors ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-25
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2020.09.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1501: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 48: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Repeated Pulses of Methyl-Prednisolone in Adults Hospitalized With COVID-19 Pneumonia and Acute Respiratory Distress Syndrome: A Preliminary Before-After Study (CortiCOVID Study).

    Espinosa-Solano, Michelle / Gonzalez-Vergara, Demetrio / Ferrer-Galvan, Marta / Asensio-Cruz, Maria Isabel / Lomas, Jose M / Roca-Oporto, Cristina / Navarro-Amuedo, Maria Dolores / Paniagua-Garcia, Maria / Sotomayor, Cesar / Espinosa, Nuria / Garcia-Gutierrez, Manuel / Molina Gil-Bermejo, Jose / Aguilar-Guisado, Manuela / Poyato, Manuel / Praena-Segovia, Julia / Palomo, Alejandro / Borrero-Rodriguez, Macarena / Cordero, Elisa / Caballero-Eraso, Candela /
    Jara-Palomares, Luis

    Open respiratory archives

    2021  Volume 3, Issue 2, Page(s) 100086

    Abstract: Introduction: The use of systemic corticosteroids in severely ill patients with coronavirus disease 2019 (COVID-19) is controversial. We aimed to evaluate the efficacy and safety of corticosteroid pulses in patients with COVID-19 pneumonia.: Methods: ...

    Abstract Introduction: The use of systemic corticosteroids in severely ill patients with coronavirus disease 2019 (COVID-19) is controversial. We aimed to evaluate the efficacy and safety of corticosteroid pulses in patients with COVID-19 pneumonia.
    Methods: A quasi-experimental study, before and after, was performed in a tertiary referral hospital, including admitted patients showing COVID-19-associated pneumonia. The standard treatment protocol included targeted COVID-19 antiviral therapy from 23rd March 2020, and additionally pulses of methylprednisolone from 30th March 2020. The primary outcome was a composite endpoint combining oro-tracheal intubation (OTI) and death within 7 days.
    Results: A total of 24 patients were included. Standard of care (SOC) (before intervention) was prescribed in 14 patients, while 10 received SOC plus pulses of methylprednisolone (after intervention). The median age of patients was 64.5 years and 83.3% of the patients were men. The primary composite endpoint occurred in 13 patients (92.9%) who received SOC vs. 2 patients (20%) that received pulses of methylprednisolone (odds ratio, 0.02; 95% confidence interval, 0.001 to 0.25;
    Conclusions: In patients with severe pneumonia due to COVID-19, the administration of methylprednisolone pulses was associated with a lower rate of OTI and/or death and a shorter hospitalization episode.
    Language English
    Publishing date 2021-03-19
    Publishing country Spain
    Document type Journal Article
    ISSN 2659-6636
    ISSN (online) 2659-6636
    DOI 10.1016/j.opresp.2021.100086
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Conventional Hospitalization versus Sequential Outpatient Parenteral Antibiotic Therapy for

    Castillo-Fernández, Nerea / Pérez-Crespo, Pedro María Martínez / Salamanca-Rivera, Elena / Herrera-Hidalgo, Laura / de Alarcón, Arístides / Navarro-Amuedo, María Dolores / Marrodán Ciordia, Teresa / Pérez-Rodríguez, María Teresa / Sevilla-Blanco, Juan / Jover-Saenz, Alfredo / Fernández-Suárez, Jonathan / Armiñanzas-Castillo, Carlos / Reguera-Iglesias, José María / Natera Kindelán, Clara / Boix-Palop, Lucía / León Jiménez, Eva / Galán-Sánchez, Fátima / Del Arco Jiménez, Alfonso / Bahamonde-Carrasco, Alberto /
    Vinuesa García, David / Smithson Amat, Alejandro / Cuquet Pedragosa, Jordi / Reche Molina, Isabel María / Pérez Camacho, Inés / Merino de Lucas, Esperanza / Gutiérrez-Gutiérrez, Belén / Rodríguez Baño, Jesús / López Cortés, Luis Eduardo

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 1

    Abstract: It is not known whether sequential outpatient parenteral antimicrobial (OPAT) is as safe and effective as conventional hospitalization in patients with S. aureus bacteremia (SAB). A post-hoc analysis of the comparative effectiveness of conventional ... ...

    Abstract It is not known whether sequential outpatient parenteral antimicrobial (OPAT) is as safe and effective as conventional hospitalization in patients with S. aureus bacteremia (SAB). A post-hoc analysis of the comparative effectiveness of conventional hospitalization versus sequential OPAT was performed in two prospective Spanish cohorts of patients with S. aureus bacteremia. The PROBAC cohort is a national, multicenter, prospective observational cohort of patients diagnosed in 22 Spanish hospitals between October 2016 and March 2017. The DOMUS OPAT cohort is a prospective observational cohort including patients from two university hospitals in Seville, Spain from 2012 to 2021. Multivariate regression was performed, including a propensity score (PS) for receiving OPAT, stratified analysis according to PS quartiles, and matched pair analyses based on PS. Four hundred and thirteen patients were included in the analysis: 150 in sequential OPAT and 263 in the full hospitalization therapy group. In multivariate analysis, including PS and center effect as covariates, 60-day treatment failure was lower in the OPAT group than in the full hospitalization group (p < 0.001; OR 0.275, 95%CI 0.129−0.584). In the PS-based matched analyses, sequential treatment under OPAT was not associated with higher 60-day treatment failure (p = 0.253; adjusted OR 0.660; % CI 0.324−1.345). OPAT is a safe and effective alternative to conventional in-patient therapy for completion of treatment in well-selected patients with SAB, mainly those associated with a low-risk source and without end-stage kidney disease.
    Language English
    Publishing date 2023-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12010129
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: A quick prediction tool for unfavourable outcome in COVID-19 inpatients: Development and internal validation

    Salto-Alejandre, Sonsoles / Roca-Oporto, Cristina / Martín-Gutiérrez, Guillermo / Avilés, María Dolores / Gómez-González, Carmen / Navarro-Amuedo, María Dolores / Praena-Segovia, Julia / Molina, José / Paniagua-García, María / García-Delgado, Horacio / Domínguez-Petit, Antonio / Pachón, Jerónimo / Cisneros, José Miguel

    J. infect

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #795715
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Impact of the COVID-19 Pandemic on Antimicrobial Consumption and Hospital-Acquired Candidemia and Multidrug-Resistant Bloodstream Infections

    Guisado-Gil, Ana Belen Infante-Domínguez Carmen Peñalva Germán Praena Julia Roca Cristina Navarro-Amuedo María Dolores Aguilar-Guisado Manuela Espinosa-Aguilera Nuria Poyato-Borrego Manuel Romero-Rodríguez Nieves Aldabó Teresa Salto-Alejandre Sonsoles Ruiz-Pérez de Pipaón Maite Lepe José Antonio Martín-Gutiérrez Guillermo Gil-Navarro María Victoria Molina José Pachón Jerónimo Cisneros José Miguel Team On behalf of the PRIOAM

    Antibiotics

    Abstract: During the COVID-19 pandemic, the implementation of antimicrobial stewardship strategies has been recommended This study aimed to assess the impact of the COVID-19 pandemic in a tertiary care Spanish hospital with an active ongoing antimicrobial ... ...

    Abstract During the COVID-19 pandemic, the implementation of antimicrobial stewardship strategies has been recommended This study aimed to assess the impact of the COVID-19 pandemic in a tertiary care Spanish hospital with an active ongoing antimicrobial stewardship programme (ASP) For a 20-week period, we weekly assessed antimicrobial consumption, incidence density, and crude death rate per 1000 occupied bed days of candidemia and multidrug-resistant (MDR) bacterial bloodstream infections (BSI) We conducted a segmented regression analysis of time series Antimicrobial consumption increased +3 5% per week (p = 0 016) for six weeks after the national lockdown, followed by a sustained weekly reduction of −6 4% (p = 0 001) The global trend for the whole period was stable The frequency of empirical treatment of patients with COVID-19 was 33 7% No change in the global trend of incidence of hospital-acquired candidemia and MDR bacterial BSI was observed (+0 5% weekly;p = 0 816), nor differences in 14 and 30-day crude death rates (p = 0 653 and p = 0 732, respectively) Our work provides quantitative data about the pandemic effect on antimicrobial consumption and clinical outcomes in a centre with an active ongoing institutional and education-based ASP However, assessing the long-term impact of the COVID-19 pandemic on antimicrobial resistance is required
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #926667
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Book ; Online: A quick prediction tool for unfavourable outcome in COVID-19 inpatients:development and internal validation ; Predicting outcome in COVID-19 patients

    Salto-Alejandre, Sonsoles / Roca-Oporto, Cristina / Martín-Gutiérrez, Guillermo / Avilés, María Dolores / Gómez-González, Carmen / Navarro-Amuedo, María Dolores / Praena-Segovia, Julia / Molina, José / Paniagua-García, María / García-Delgado, Horacio / Domínguez-Petit, Antonio / Pachón, Jerónimo / Cisneros, José Miguel

    2020  

    Abstract: As COVID-19 pandemic continues to escalate, hospitals around the world confront with the need to attend an increasing number of patients. Therefore, we read with much interest the recent study published in the Journal of Infection by Galloway JB et al., ... ...

    Abstract As COVID-19 pandemic continues to escalate, hospitals around the world confront with the need to attend an increasing number of patients. Therefore, we read with much interest the recent study published in the Journal of Infection by Galloway JB et al., reinforcing the importance of stratifying patients to ease their management and their incorporation to potential clinical trials [1]. For this purpose, these authors developed a valuable and complex risk score based on twelve parameters, including, among others, age, gender, diabetes mellitus, hypertension, and chronic lung disease. Since knowing the risk of clinical deterioration can assist medical decisions about appropriate level of care, predictive models for COVID-19 are becoming notably frequent. However, many of them are notably biased, non-validated, or present a construction lacking in clarity [2,3]. Moreover, they often conclude that male older patients with comorbidities are more likely to experience unfavourable outcomes [4,5], even when such determinants are already well-known predictors of worse result in community-acquired pneumonia [6]. Although the medical assessment of patients must always address demographics and underlying comorbidities, it is known that the evaluation of disease severity and prognosis should not only depend on the above-mentioned risk markers.

    No
    Keywords Quick prediction tool ; Unfavourable outcomeInternal validation ; COVID-19 ; SARS-CoV-2 ; covid19
    Subject code 610
    Language English
    Publishing date 2020-09-25
    Publisher Elsevier BV
    Publishing country es
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: A quick prediction tool for unfavourable outcome in COVID-19 inpatients

    Salto-Alejandre, Sonsoles / Roca-Oporto, Cristina / Martín-Gutiérrez, Guillermo / Avilés, María Dolores / Gómez-González, Carmen / Navarro-Amuedo, María Dolores / Praena-Segovia, Julia / Molina, José / Paniagua-García, María / García-Delgado, Horacio / Domínguez-Petit, Antonio / Pachón, Jerónimo / Cisneros, José Miguel

    Journal of Infection ; ISSN 0163-4453

    Development and internal validation

    2020  

    Keywords Microbiology (medical) ; Infectious Diseases ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.jinf.2020.09.023
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article: Impact of the COVID-19 Pandemic on Antimicrobial Consumption and Hospital-Acquired Candidemia and Multidrug-Resistant Bloodstream Infections.

    Guisado-Gil, Ana Belen / Infante-Domínguez, Carmen / Peñalva, Germán / Praena, Julia / Roca, Cristina / Navarro-Amuedo, María Dolores / Aguilar-Guisado, Manuela / Espinosa-Aguilera, Nuria / Poyato-Borrego, Manuel / Romero-Rodríguez, Nieves / Aldabó, Teresa / Salto-Alejandre, Sonsoles / Ruiz-Pérez de Pipaón, Maite / Lepe, José Antonio / Martín-Gutiérrez, Guillermo / Gil-Navarro, María Victoria / Molina, José / Pachón, Jerónimo / Cisneros, José Miguel /
    On Behalf Of The Prioam Team

    Antibiotics (Basel, Switzerland)

    2020  Volume 9, Issue 11

    Abstract: During the COVID-19 pandemic, the implementation of antimicrobial stewardship strategies has been recommended. This study aimed to assess the impact of the COVID-19 pandemic in a tertiary care Spanish hospital with an active ongoing antimicrobial ... ...

    Abstract During the COVID-19 pandemic, the implementation of antimicrobial stewardship strategies has been recommended. This study aimed to assess the impact of the COVID-19 pandemic in a tertiary care Spanish hospital with an active ongoing antimicrobial stewardship programme (ASP). For a 20-week period, we weekly assessed antimicrobial consumption, incidence density, and crude death rate per 1000 occupied bed days of candidemia and multidrug-resistant (MDR) bacterial bloodstream infections (BSI). We conducted a segmented regression analysis of time series. Antimicrobial consumption increased +3.5% per week (
    Keywords covid19
    Language English
    Publishing date 2020-11-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics9110816
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top