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Article ; Online: Sexual disorders beyond DSM-5: the unfinished affaire.

Navarro-Cremades, Felipe / Simonelli, Chiara / Montejo, Angel L

2017 Volume 30, Issue 6, Page(s) 417–422

Abstract: Purpose of review: To provide an overview of post-The Diagnostic and Statistical Manual of Mental Disorders, 5th ed. classifications related to human sexuality. After reviewing the literature on classification and clinical practice of sexual disorders, ... ...

Abstract	Purpose of review: To provide an overview of post-The Diagnostic and Statistical Manual of Mental Disorders, 5th ed. classifications related to human sexuality. After reviewing the literature on classification and clinical practice of sexual disorders, some of the most important contributions on main sexological classifications and frameworks were selected, especially from January 2016 till June 2017. Recent findings: New relevant contributions on psychiatric and sexological classifications and frameworks have been proposed, such as the international classification of diseases 11th revision (ICD-11), research domain criteria, the third edition of the Diagnostic Manual in Sexology and the person-centered psychiatry perspective. Summary: ICD-11 proposals regarding conditions related to sexual health including sexual dysfunctions and gender incongruence as well as vaginismus, such as sexual pain disorder, paraphilic disorders as mental Disorders. The disorders associated with sexual development and orientation, are proposed for deletion. The other perspectives aforementioned are also presented.
Language	English
Publishing date	2017-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	645162-7
ISSN	1473-6578 ; 0951-7367
ISSN (online)	1473-6578
ISSN	0951-7367
DOI	10.1097/YCO.0000000000000367
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Article ; Online: Male Sexual Desire: An Overview of Biological, Psychological, Sexual, Relational, and Cultural Factors Influencing Desire.

Nimbi, Filippo Maria / Tripodi, Francesca / Rossi, Roberta / Navarro-Cremades, Felipe / Simonelli, Chiara

Sexual medicine reviews

2019 Volume 8, Issue 1, Page(s) 59–91

Abstract: Introduction: The literature showed the need for a better understanding of the male sexual response, which has historically been considered as simpler and more mechanistic compared with that in women.: Aim: To examine the literature on ... ...

Abstract	Introduction: The literature showed the need for a better understanding of the male sexual response, which has historically been considered as simpler and more mechanistic compared with that in women. Aim: To examine the literature on biopsychosocial factors associated with the level of sexual desire in men and discuss some interesting directions for future research. Methods: A systematic literature review was conducted. Main outcome measures: 169 articles published in Google Scholar, Web of Science, Scopus, EBSCO, and Cochrane Library about male sexual desire and related biopsychosocial factors. Results: We found a lack of multidimensional studies on male sexual desire. Most existing research has focused on hypoactive sexual desire disorder in coupled heterosexual men. Biological factors play important roles in the level of sexual desire, but they are insufficient to explain the male sexual response. Psychological, relational, and sexual factors (eg depression, anxiety, emotions, attraction, conflicts, communication, sexual functioning, distress, satisfaction) are involved in the development/maintenance of lack of sexual interest in men. Cultural influence is also relevant, with cognitive factors linked to gender roles and sexual scripts of masculinity identified as important predictors of low sexual desire. Conclusion: Male sexual desire is characterized by an interplay among biological, psychological, sexual, relational, and cultural elements. This interplay merits further study to better understand how sexual desire works and how treatments for low sexual interest could be improved. Nimbi FM,Tripodi F, Rossi R, et al. Male Sexual Desire: An Overview of Biological, Psychological, Sexual, Relational, and Cultural Factors Influencing Desire. Sex Med Rev 2020;8:59-91.
Language	English
Publishing date	2019-02-22
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2722257-3
ISSN	2050-0521 ; 2050-0513
ISSN (online)	2050-0521
ISSN	2050-0513
DOI	10.1016/j.sxmr.2018.12.002
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Zs.A 6997: Show issues

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Article ; Online: Validez en la predicción de riesgo de la escala SCORE en una población mediterránea con hipertensión arterial.

Sanz-Garcia, Francisco J / Quesada, José A / Carratala-Munuera, Concepción / Orozco-Beltrán, Domingo / Gil-Guillén, Vicente F / Prieto-Castello, María J / Marhuenda-Amorós, Dolores / Micó Pérez, Rafael M / Navarro Cremades, Felipe / Cordero, Alberto / Bertomeu-Gonzalez, Vicente / Arrarte, Vicente

Medicina clinica

2023 Volume 162, Issue 3, Page(s) 112–117

Abstract: Introduction and objectives: Hypertension is the most prevalent risk factor globally. Calculation of cardiovascular risk in hypertensive patients before initiation of treatment is recommended. This study aimed to assess the predictive value and clinical ...

Title translation	Predictive validity of the risk SCORE model in a Mediterranean population with arterial hypertension.
Abstract	Introduction and objectives: Hypertension is the most prevalent risk factor globally. Calculation of cardiovascular risk in hypertensive patients before initiation of treatment is recommended. This study aimed to assess the predictive value and clinical utility of the SCORE scale in preventing cardiovascular events and all-cause mortality in patients with hypertension. Methods: Patients with hypertension from the ESCARVAL-RISK cohort were included. Cardiovascular risk was calculated using the SCORE scale. All deaths and cardiovascular events were recorded during a 5-year follow-up period. Sensitivity, specificity and predictive values were calculated for different cut-off points and the effect of different risk factors on the diagnostic accuracy of SCORE charts were assessed. Results: In a final cohort of 9834 patients, there were 555 cardiovascular events and 69 deaths. The recommended risk value for initiating drug treatment (5%) had a specificity of 92% for death and 91% for cardiovascular events, and a sensitivity of 20% for death and 22% for cardiovascular events. In addition, the scale classified 80.4% of patients who experienced a cardiovascular event and 78.3% of those who died as low risk. Age, body mass index, retinopathy and anticoagulant therapy were associated with reduced predictive ability of the SCORE scale, while being female was associated with better risk prediction. Conclusions: The predictive ability of the SCORE scale for cardiovascular disease and total mortality in patients with hypertension is limited.
MeSH term(s)	Humans ; Female ; Male ; Hypertension/complications ; Hypertension/diagnosis ; Hypertension/drug therapy ; Risk Factors ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/etiology ; Body Mass Index ; Heart Disease Risk Factors
Language	Spanish
Publishing date	2023-11-02
Publishing country	Spain
Document type	Journal Article
ZDB-ID	411607-0
ISSN	1578-8989 ; 0025-7753
ISSN (online)	1578-8989
ISSN	0025-7753
DOI	10.1016/j.medcli.2023.09.009
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Ua VI Zs.279: Show issues

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Article ; Online: Sexual side-effects of antidepressant and antipsychotic drugs.

Montejo, Angel L / Montejo, Laura / Navarro-Cremades, Felipe

Current opinion in psychiatry

2015 Volume 28, Issue 6, Page(s) 418–423

Abstract: Purpose of review: Psychotropic-related sexual dysfunction is a quite frequent issue in clinical practice, mainly in chronic treatments affecting both quality of life and compliance.: Recent findings: In the last decade fortunately antidepressants ... ...

Abstract	Purpose of review: Psychotropic-related sexual dysfunction is a quite frequent issue in clinical practice, mainly in chronic treatments affecting both quality of life and compliance. Recent findings: In the last decade fortunately antidepressants and antipsychotic compounds have been deeply screened in order to identify sexual adverse events that were commonly underdiagnosed and previously underestimated by clinicians and perhaps by pharmaceutical companies as well. Some differences in the mechanism of action are the nucleus of this poorly tolerated adverse event. All antidepressants with serotonergic activity can cause mild to severe sexual dysfunction such as decreased libido and delayed orgasm frequently (>60%) or anorgasmia and arousal difficulties sometimes (30%). In contrast, noradrenergic, dopaminergic, or melatonergic antidepressants do not cause sexual dysfunction but perhaps the clinical profile of patients receiving these compounds could be different. Antipsychotics that highly increase prolactin levels and strongly block dopamine receptors could be related to sexual dysfunction as well. Unfortunately, these dysfunctions are present during the long term after the antipsychotic onset to provide continued symptom control and enable recovery. Young patients suffering psychosis and concomitant sexual dysfunction (erectile and/or orgasmic difficulties) tend to show poor compliance in chronic treatments affecting the outcomes. Summary: The implications of psychotropic-related sexual dysfunction in clinical practice are relevant mainly in patients under long-term treatment with previous satisfactory sexual life. Implications for future research about sexual dysfunction in all new treatments should be strongly taken into account.
MeSH term(s)	Antidepressive Agents/administration & dosage ; Antidepressive Agents/adverse effects ; Antidepressive Agents/pharmacology ; Antipsychotic Agents/administration & dosage ; Antipsychotic Agents/adverse effects ; Antipsychotic Agents/pharmacology ; Erectile Dysfunction/chemically induced ; Female ; Humans ; Libido/drug effects ; Male ; Medication Adherence ; Orgasm/drug effects ; Psychotic Disorders/drug therapy ; Psychotic Disorders/metabolism ; Psychotropic Drugs/adverse effects ; Quality of Life ; Receptors, Dopamine/drug effects ; Receptors, Serotonin/drug effects ; Sexual Behavior/drug effects ; Sexual Dysfunctions, Psychological/chemically induced
Chemical Substances	Antidepressive Agents ; Antipsychotic Agents ; Psychotropic Drugs ; Receptors, Dopamine ; Receptors, Serotonin
Language	English
Publishing date	2015-11
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	645162-7
ISSN	1473-6578 ; 0951-7367
ISSN (online)	1473-6578
ISSN	0951-7367
DOI	10.1097/YCO.0000000000000198
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Article: Impact of Anal Fissure on Neuroticism, Extraversion, Openness to Experience, Agreeableness, and Conscientiousness: A Case-Control Study.

Luri-Prieto, Paloma / Candela-Gomis, Asunción / Palazón-Bru, Antonio / Navarro-Cremades, Felipe / Gil-Guillén, Vicente Francisco / Compañ-Rosique, Antonio Fernando

Visceral medicine

2020 Volume 37, Issue 2, Page(s) 128–133

Abstract: Introduction: Scientific literature on determining patterns of personality traits in patients with anal fissure is limited.: Objectives: To determine whether certain common psychological traits are associated with anal fissure.: Methods: A case- ... ...

Abstract	Introduction: Scientific literature on determining patterns of personality traits in patients with anal fissure is limited. Objectives: To determine whether certain common psychological traits are associated with anal fissure. Methods: A case-control study was carried out in Spain in 2016-2017. Patients with acute or chronic idiopathic anal fissure ( Results: Three significant traits were noted: (1) greater neuroticism in the cases (OR 1.19, 95% CI 1.08-1.32, Conclusions: The cases mainly presented higher levels of neuroticism and lower levels of openness to experience and conscientiousness. Further studies are needed to corroborate our results.
Language	English
Publishing date	2020-05-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2850733-2
ISSN	2297-475X ; 2297-4725
ISSN (online)	2297-475X
ISSN	2297-4725
DOI	10.1159/000507382
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Zs.A 2103: Show issues

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Article ; Online: Sexual Quality of Life After Treatment of Stress Urinary Incontinence With Adjustable Tension-free Mesh System in Women Who Were Sexually Active Before Surgery.

Pérez-Tomás, Carla / Gómez-Pérez, Luis / Romero-Maroto, Jesús / Palazón-Bru, Antonio / Navarro-Cremades, Felipe / Cortés-Castell, Ernesto

Urology

2018 Volume 115, Page(s) 76–81

Abstract: Objective: To assess the sexuality and quality of life of sexually active women with stress or mixed urinary incontinence (SUI or MUI) after surgery with adjustable tension-free suburethral mesh system (transobturator adjustable tape or transvaginal ... ...

Abstract	Objective: To assess the sexuality and quality of life of sexually active women with stress or mixed urinary incontinence (SUI or MUI) after surgery with adjustable tension-free suburethral mesh system (transobturator adjustable tape or transvaginal adjustable tape). Materials and methods: This intervention study with 2 years of follow-up (visits at 3 months, 1 year, and 2 years) involved 60 women with SUI or MUI who underwent surgery using transobturator adjustable tape or transvaginal adjustable tape during 2008-2014 in a Spanish region. The variables of interest measured pre- and postintervention were the global scores on the following questionnaires: (1) the Pelvic Organ Prolapse Urinary Incontinence Sexual Questionnaire-12; (2) the International Consultation on Incontinence Questionnaire; and (3) the Incontinence Quality of Life Questionnaire. Mixed linear models were constructed to determine the effect of the intervention on the outcome variables. Results: A significant improvement (P <.001) was seen over time in all the questionnaires, although between the 1- and 2-year visits there was a slight deterioration in all of them. Conclusion: The technique provided an improved quality of life and sexuality, which was maintained at all the postoperative visits compared with baseline.
MeSH term(s)	Adult ; Female ; Follow-Up Studies ; Humans ; Middle Aged ; Quality of Life ; Sexual Behavior ; Suburethral Slings ; Surgical Mesh ; Surveys and Questionnaires ; Urinary Incontinence, Stress/surgery
Language	English
Publishing date	2018-03-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	192062-5
ISSN	1527-9995 ; 0090-4295
ISSN (online)	1527-9995
ISSN	0090-4295
DOI	10.1016/j.urology.2018.02.031
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Zs.A 1142: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Validation of the Center of Applied Psychology Female Sexuality Questionnaire (CAPFS-Q).

Tirado-González, Sonia / Navarro-Sánchez, Antonio / Compañ-Rosique, Antonio / Luri-Prieto, Paloma / Rodríguez-Marín, Jesús / Van-der Hofstadt-Román, Carlos J / Berenguer Soler, María / Navarro-Cremades, Felipe / Gil-Guillén, Vicente F / Navarro Ortiz, Ramón / Montejo, Angel L / Pérez-Jover, Virtudes

Journal of clinical medicine

2021 Volume 10, Issue 12

Abstract: Instruments for the measurement of human sexuality include self-report measures used to assess sexual functioning, but many of them have not yet been validated. The Center of Applied Psychology Female Sexual Questionnaire (CAPFS-Q) is an original self- ... ...

Abstract	Instruments for the measurement of human sexuality include self-report measures used to assess sexual functioning, but many of them have not yet been validated. The Center of Applied Psychology Female Sexual Questionnaire (CAPFS-Q) is an original self-report instrument. It has been developed for the study of sexuality in specific non-clinical populations, such as female university students of Medicine and other Health Sciences. The CAPFS-Q includes 26 items, organized as follows: sociodemographic and relevant data (four items); aspects of sexual relations with partner (five items); sexual practices (12 from 13 items); and dysfunctional aspects of sexual relations (four items). CAPFS-Q validity and reliability were examined in a sample of Spanish female university students of Health Sciences. Exploratory and confirmatory factor analysis (FA) showed a four-factor structure which explained 71.6% of the variance. This initial version of the CAPFS-Q is a reliable measure of women's sexual behavior, with a dimensionality that replicates the initial theoretical content and with adequate indicators of internal consistency, validity, and test-retest reliability. It is easy to administer and to complete.
Language	English
Publishing date	2021-06-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm10122686
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Article: Sexuality, Quality of Life, Anxiety, Depression, and Anger in Patients with Anal Fissure. A Case-Control Study.

Navarro-Sánchez, Antonio / Luri-Prieto, Paloma / Compañ-Rosique, Antonio / Navarro-Ortiz, Ramón / Berenguer-Soler, María / Gil-Guillén, Vicente F / Cortés-Castell, Ernesto / Navarro-Cremades, Felipe / Gómez-Pérez, Luis / Pérez-Tomás, Carla / Palazón-Bru, Antonio / Montejo, Angel L / Pérez-Jover, Virtudes

Journal of clinical medicine

2021 Volume 10, Issue 19

Abstract: Anal fissures (AFs) are lesions located in the lower anal canal. They can be primary (chronic or acute) or secondary to a basic disease. There is high comorbidity of depression and anxiety in patients with chronic AF, with poorer quality of life (QoL) ... ...

Abstract	Anal fissures (AFs) are lesions located in the lower anal canal. They can be primary (chronic or acute) or secondary to a basic disease. There is high comorbidity of depression and anxiety in patients with chronic AF, with poorer quality of life (QoL) and sexual function. This is a case-control study carried out in the San Juan Hospital (Alicante, Spain). Sixty-seven participants were included in the study, including 35 cases and 32 controls: 36 males and 31 females. This study aims to investigate the association of presenting AFs with sexuality, quality of life, anxiety, depression, and anger. The instruments used were the Spanish validated versions of the validated original selected questionnaires. These instruments were used to assess health-related quality of life, anxiety, anger, depression, and sexual function. Results show higher values in cases than in controls with statistical significance in anxiety state and trait; anxiety and depression; bodily pain, general health, and vitality; and 10 of the 12 anger factors. Higher values in controls than in cases with statistical significance in sexuality and many of the QoL factors were found. Addressing these issues in AF surgical patients would be beneficial for their clinical assessment and intervention.
Language	English
Publishing date	2021-09-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm10194401
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Article ; Online: Sexual functioning in women with mild and severe symptoms of Charcot-Marie-Tooth disease.

Gargiulo, Paola / Vinci, Paola / Navarro-Cremades, Felipe / Rellini, Alessandra H

The journal of sexual medicine

2013 Volume 10, Issue 7, Page(s) 1800–1806

Abstract: Introduction: Charcot-Marie-Tooth (CMT) disease is one of the most frequently inherited neurological disorders, and while it is known that individuals suffering from this condition have low quality of life, little is known about their sexual function ... ...

Abstract	Introduction: Charcot-Marie-Tooth (CMT) disease is one of the most frequently inherited neurological disorders, and while it is known that individuals suffering from this condition have low quality of life, little is known about their sexual function and satisfaction. Aim: To describe the functioning on different domains of sexuality in a relatively large sample of women with CMT, provide comparisons between mildly and severely affected patients and between women with the two different types of CMT (demyelinating vs. axonal), and assess the relationship between sexual function and age of onset. Methods: Fifty-seven women (age: 18-60 years) were approached in a CMT rehabilitation clinic by a psychologist and administered the Italian version of the McCoy Female Sexuality Questionnaire (MFSQ). Data from 40 patients who had had sexual intercourse in the previous 4 weeks were analyzed. Main outcome measure: The main outcome measures are the factors MFSQ-SEX and MFSQ-PARTNER, which describe sexual functioning and sexual satisfaction with a partner, respectively. Results: Almost 30% of women did not engage in sexual intercourse with a partner. Overall sexual problems were more prominent in younger women and tended to be lower as age increased: this pattern was different from what was reported in previous studies in comparable samples of healthy Italian women. Severity of CMT was associated with better sexual functioning in the areas of desire, arousal, orgasm, and satisfaction, with women with more severe symptoms reporting greater functioning. Women with more severe CMT symptoms reported more pain during intercourse. Age of CMT onset and type of CMT (demyelinating vs. axonal) were not associated with differences in sexual functioning. Conclusions: Findings point to the importance of including assessment of sexual dysfunction in young women with mild CMT symptoms and the importance of providing sex therapy or counseling to these patients.
MeSH term(s)	Adolescent ; Adult ; Charcot-Marie-Tooth Disease/epidemiology ; Charcot-Marie-Tooth Disease/psychology ; Dyspareunia/epidemiology ; Female ; Humans ; Italy/epidemiology ; Middle Aged ; Orgasm ; Sex Factors ; Sexual Dysfunctions, Psychological/epidemiology ; Sexual Dysfunctions, Psychological/psychology ; Sexuality ; Surveys and Questionnaires ; Young Adult
Language	English
Publishing date	2013-03-27
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2251959-2
ISSN	1743-6109 ; 1743-6095
ISSN (online)	1743-6109
ISSN	1743-6095
DOI	10.1111/jsm.12126
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Zs.MO 505: Show issues

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Article: Genito Pelvic Pain/Penetration Disorder (GPPPD) in Spanish Women-Clinical Approach in Primary Health Care: Review and Meta-Analysis.

Berenguer-Soler, María / Navarro-Sánchez, Antonio / Compañ-Rosique, Antonio / Luri-Prieto, Paloma / Navarro-Ortiz, Ramón / Gómez-Pérez, Luis / Pérez-Tomás, Carla / Font-Juliá, Elsa / Gil-Guillén, Vicente F / Cortés-Castell, Ernesto / Navarro-Cremades, Felipe / Montejo, Angel L / Arroyo-Sebastián, María Del Ángel / Pérez-Jover, Virtudes

Journal of clinical medicine

2022 Volume 11, Issue 9

Abstract: Sexuality is a component of great relevance in humans. Sexual disorders are a major public health problem representing a high prevalence in the general population. DSM-5 genito-pelvic pain/penetration disorder (GPPPD) includes dyspareunia and vaginismus ( ...

Abstract	Sexuality is a component of great relevance in humans. Sexual disorders are a major public health problem representing a high prevalence in the general population. DSM-5 genito-pelvic pain/penetration disorder (GPPPD) includes dyspareunia and vaginismus (DSM-IV-TR). To assess the importance of research on these disorders in Spain, we evaluated the Spanish scientific publications of primary and community care. The objective was to quantify the magnitude of the publications of GPPPD in Spanish women in primary and community care. For this, we used the method of conducting a systematic review and meta-analysis of studies evaluating GPPPD. As main results, of the 551 items found, we selected 11 studies that met the inclusion criteria. In primary care in Spain, one in nine women has these disorders; the percentage of women with GPPPD in this study (raw data) was 11.23% (95% CI: 0-29%) (vaginismus 5%; penetration pain 8.33%; dyspareunia 16.45%). These percentages can differ of those from other countries, and they are at the top of the data of the European countries (9-11.9%). There is much variability in the studies found in the world with respect to the prevalence of these health problems.
Language	English
Publishing date	2022-04-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm11092340
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