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  1. Article ; Online: Usefulness of a circumferential wound retractor in emergency colorectal surgery as a preventive measure for surgical site infection. Alexis O-Ring® and emergency surgery.

    Salgado-Nesme, N / Morales-Cruz, M / Navarro-Navarro, A / Patiño-Gómez, T A / Vergara-Fernández, O

    Revista de gastroenterologia de Mexico (English)

    2020  Volume 85, Issue 4, Page(s) 399–403

    Abstract: Introduction and aims: More than 20% of healthcare-associated infections correspond to those at surgical sites, and there is a higher incidence of infections in colorectal surgery due to the associated bacterial load. Surgical wound protectors are ... ...

    Title translation Utilidad del separador circunferencial para herida en cirugía colorrectal de urgencia como medida preventiva para infección del sitio quirúrgico. El Alexis O-Ring® y la cirugía de urgencia.
    Abstract Introduction and aims: More than 20% of healthcare-associated infections correspond to those at surgical sites, and there is a higher incidence of infections in colorectal surgery due to the associated bacterial load. Surgical wound protectors are designed to prevent contamination and mechanical trauma. Our aim was to demonstrate the usefulness of a circumferential wound retractor/protector for the prevention of surgical site infections (SSIs) in emergency colorectal surgery.
    Methods: Forty-one patients that underwent emergency open surgery at a tertiary care hospital were randomized into 2 groups: 20 cases without the retractor (group A) and 21 cases with the retractor (group B). Subjects were assigned to a group in a 1:1 randomization allocation ratio. The chi-square and Fisher's exact tests were employed for the quantitative variables, and the statistical analysis was performed using the IBM Statistical Package for the Social Sciences software for Mac, version 16.0 (IBM SPSS Inc., Chicago, IL, USA).
    Results: The SSI rate was 17%. Six group A patients developed SSI versus one group B patient. The use of a circumferential wound retractor/protector was statistically significant for the prevention of surgical wound infections, with a P=.031 and an OR of 8.5. In addition, preoperative blood glucose levels below 200mg/dl provided a 3.2-times higher protective effect, compared with glucose levels above 200mg/dl.
    Conclusions: In the present prospective randomized pilot study, the use of the circumferential wound retractor/protector significantly decreased the likelihood of SSI in emergency colorectal surgery.
    Language Spanish
    Publishing date 2020-05-26
    Document type Journal Article
    ISSN 2255-534X
    ISSN (online) 2255-534X
    DOI 10.1016/j.rgmx.2019.08.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Posterior bilateral lens luxation in an agitated patient: Cause or consequence?

    Monera Lucas, C E / Escolano Serrano, J / Romero Valero, D / Fernández Martínez, C / Navarro Navarro, A / Martínez Toldos, J J

    Archivos de la Sociedad Espanola de Oftalmologia

    2020  Volume 96, Issue 2, Page(s) 93–96

    Abstract: Complete posterior lens dislocation is an infrequent clinical entity. Trauma is the first cause of secondary lens dislocation. Most of the cases are unilateral, and bilateral cases are unusual. We report the uncommon case of a 70-year-old woman with ... ...

    Title translation Luxación posterior bilateral del cristalino en una paciente agitada, ¿causa o consecuencia?
    Abstract Complete posterior lens dislocation is an infrequent clinical entity. Trauma is the first cause of secondary lens dislocation. Most of the cases are unilateral, and bilateral cases are unusual. We report the uncommon case of a 70-year-old woman with evidence of a posterior bilateral dislocation of the lens in the context of an acute onset of confusional syndrome. We discuss about sensory deprivation as a trigger for acute confusion and agitation in patients with predisposing conditions. In addition, we describe the benefits that, in our experience, the refloating technique with perfluorocarbon liquid provides for the surgical approach to these cases.
    Language Spanish
    Publishing date 2020-08-29
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5794
    ISSN (online) 2173-5794
    DOI 10.1016/j.oftal.2020.07.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Deloyers procedure compared to ileorectal anastomosis as restoration techniques of bowel continuity after extended left colon resection.

    Carpinteyro-Espín, Paulina / Santes, Oscar / Moctezuma-Velazquez, Paulina / Navarro-Iñiguez, Julio A / Navarro-Navarro, Adolfo / Salgado-Nesme, Noel

    ANZ journal of surgery

    2022  Volume 93, Issue 4, Page(s) 956–962

    Abstract: Background: Restoration of bowel continuity after left extended colectomy may be challenging because the remaining colon may not reach the rectal stump without tension to perform a safe anastomosis. Performing a total colectomy with ileorectal ... ...

    Abstract Background: Restoration of bowel continuity after left extended colectomy may be challenging because the remaining colon may not reach the rectal stump without tension to perform a safe anastomosis. Performing a total colectomy with ileorectal anastomosis (IRA) is an option, but the quality of life can be significantly impaired due to loose stools and an increase in bowel frequency. In contrast, the preservation of the right colon and ileocaecal valve in the Deloyers procedure (DP) might ensure a better stool consistency and bowel transit, and therefore a superior quality of life.
    Materials and methods: A transverse study comparing patients that underwent DP versus patients with an IRA was performed. Postoperative morbidity, mortality, functional outcomes, and quality of life were analysed between groups. Quality of life after the surgical procedure was assessed with the SF-36 V2® health survey.
    Results: A total of 16 patients with DP and 32 with IRA were included. The groups had similar demographic characteristics concerning age, sex, body mass index, ASA classification, diagnosis and Charlson comorbidity index. The median follow-up was 55 months for DP and 99 months for IRA. Postoperative complications were similar in both groups. Patients in the DP group had fewer bowel movements (P = 0.01), tenesmus (P = 0.04) and use of loperamide (P = 0.03). DP patients achieved better scores in physical pain (P = 0.02) and general health (P < 0.01) than IRA patients.
    Conclusions: DP for intestinal continuity restoration after extended left colon resection is a safe and feasible alternative, possibly achieving better functional outcomes and quality-of-life compared to IRA.
    MeSH term(s) Humans ; Quality of Life ; Rectum/surgery ; Colon/surgery ; Anastomosis, Surgical/methods ; Colectomy/methods ; Ileum/surgery
    Language English
    Publishing date 2022-10-05
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.18084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Meta-analysis of botulinum toxin injection for chronic anal fissure: healing rates controversies.

    Vergara-Fernández, O / Salgado-Nesme, N / Navarro-Navarro, A / Rangel-Ríos, H A

    Techniques in coloproctology

    2017  Volume 21, Issue 2, Page(s) 169

    Language English
    Publishing date 2017
    Publishing country Italy
    Document type Letter ; Comment
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-016-1563-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: EXPERIENCE USING A 3D HEAD-MOUNTED DISPLAY SYSTEM IN OPHTHALMIC SURGERY.

    Martínez-Toldos, José J / Fernández-Martínez, Cristian / Navarro-Navarro, Aída

    Retina (Philadelphia, Pa.)

    2017  Volume 37, Issue 7, Page(s) 1419–1421

    Language English
    Publishing date 2017-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000001664
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reply.

    Martínez-Toldos, José J / Fernández-Martínez, Cristian / Navarro-Navarro, Aída

    Retina (Philadelphia, Pa.)

    2017  Volume 37, Issue 10, Page(s) e118

    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000001834
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The diabetic retinopathy clinical research network analysis of the cost-effectiveness of aflibercept, bevacizumab and ranibizumab for the treatment of diabetic macular oedema and its application in Spain.

    Navarro-Navarro, A / Salom, D / Martínez-Toldos, J J / Udaondo, P / Fernández-Martínez, C / Gutiérrez-Arias, L / Hervás, A / Rodrigo, R

    Archivos de la Sociedad Espanola de Oftalmologia

    2017  Volume 92, Issue 5, Page(s) 245–246

    Title translation Análisis del DRCR Network sobre coste-efectividad de aflibercept, bevacizumab y ranibizumab para el tratamiento de edema macular diabético y su aplicación en España.
    MeSH term(s) Bevacizumab/economics ; Bevacizumab/therapeutic use ; Cost-Benefit Analysis ; Diabetic Retinopathy/drug therapy ; Diabetic Retinopathy/economics ; Humans ; Macular Edema/drug therapy ; Macular Edema/economics ; Ranibizumab/economics ; Ranibizumab/therapeutic use ; Receptors, Vascular Endothelial Growth Factor/therapeutic use ; Recombinant Fusion Proteins/economics ; Recombinant Fusion Proteins/therapeutic use ; Spain
    Chemical Substances Recombinant Fusion Proteins ; aflibercept (15C2VL427D) ; Bevacizumab (2S9ZZM9Q9V) ; Receptors, Vascular Endothelial Growth Factor (EC 2.7.10.1) ; Ranibizumab (ZL1R02VT79)
    Language Spanish
    Publishing date 2017-02-16
    Publishing country Spain
    Document type Letter
    ZDB-ID 194943-3
    ISSN 1989-7286 ; 0365-6691
    ISSN (online) 1989-7286
    ISSN 0365-6691
    DOI 10.1016/j.oftal.2016.12.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Oncological Implications of Lymph Nodes Retrieval and Perineural Invasion in Colorectal Cancer: Outcomes from a Referral Center.

    Vergara-Fernandez, Omar / Navarro-Navarro, Adolfo / Rangel-Ríos, Hugo Antonio / Salgado-Nesme, Noel / Reyes-Monroy, José Aristeo / Velázquez-Fernández, David

    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

    2018  Volume 70, Issue 6, Page(s) 291–300

    Abstract: Background: In colorectal cancer (CRC), regional lymphadenectomy provides prognostic information and guides management. The current consensus states that at least 12 lymph nodes (LN) should be evaluated. The aims of this study were to identify whether ... ...

    Abstract Background: In colorectal cancer (CRC), regional lymphadenectomy provides prognostic information and guides management. The current consensus states that at least 12 lymph nodes (LN) should be evaluated. The aims of this study were to identify whether the number of LN is a predictor for survival and recurrence, and to reveal the role of LN ratio (LNR) and perineural invasion (PNI) in predicting prognosis after curative resection of CRC.
    Methods: We included all patients who underwent surgery for CRC between 2000 and 2016 in an academic medical center in Mexico. The LNR cutoff value was 0.25. We analyzed two groups according to the number of LN retrieved: Group 1 (≥ 12 LN) and Group 2 (< 12 LN).
    Results: We included 305 patients, 13.8% in Stage I, 45.6% in Stage II, and 40.6% in Stage III. The male: female ratio was 1.1. The mean age was 62.6 ± 14 years (range, 19-92). In 233 patients (76.4%), ≥ 12 LN were obtained. Recurrence rates in Groups 1 and 2 were 20.2% versus 26.4%, respectively (p = 0.16). PNI was present in 34 patients (13.2%). An LN harvest < 10 increased local and distant recurrences (p = 0.03). Stage III patients with an LNR ≥ 0.25 had higher overall recurrence rates (p = 0.012) and mortality (p = 0.029). In a multivariate Cox regression analysis, PNI-negative tumors were an independent prognostic factor for disease-free survival (p = 0.011, hazard ratio = 2.78, 95% confidence interval = 1.26-6.16).
    Conclusions: An LN retrieval < 10 increased local and distant recurrence rates. LNR was an independent prognostic factor for survival in Stage III tumors. PNI was the only significant independent prognostic factor affecting disease-free survival in our patients.
    MeSH term(s) Academic Medical Centers ; Adult ; Aged ; Aged, 80 and over ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/surgery ; Disease-Free Survival ; Female ; Humans ; Lymph Node Excision/methods ; Lymph Nodes/pathology ; Lymphatic Metastasis/pathology ; Male ; Mexico ; Middle Aged ; Multivariate Analysis ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Prognosis ; Proportional Hazards Models ; Survival Rate ; Young Adult
    Language English
    Publishing date 2018-09-19
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 138348-6
    ISSN 0034-8376
    ISSN 0034-8376
    DOI 10.24875/RIC.18002505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Advantages of Minimally Invasive Surgery for the Treatment of Colovesical Fistula.

    Salgado-Nesme, Noel / Vergara-Fernández, Omar / Espino-Urbina, Luis Alberto / Luna-Torres, Hugo Alberto / Navarro-Navarro, Adolfo

    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

    2016  Volume 68, Issue 6, Page(s) 229–304

    Abstract: Background: Colovesical fistulas in two-thirds of the cases are due to diverticular disease. In recent years, a minimally invasive approach has shown advantages over the traditional open approach. The goal of this study was to evaluate the surgical ... ...

    Abstract Background: Colovesical fistulas in two-thirds of the cases are due to diverticular disease. In recent years, a minimally invasive approach has shown advantages over the traditional open approach. The goal of this study was to evaluate the surgical results and safety of the laparoscopic procedure in patients with colovesical fistula.
    Material and methods: We retrospectively evaluated 24 patients who underwent surgery for colovesical fistula in a referral center from 2005 to 2011. Patients were divided into two groups: (i) laparoscopic approach, and (ii) open approach.
    Results: The laparoscopic and open groups had similar characteristics with respect to age and gender distribution. There were a higher number of bladder repairs in the open approach group (83.3 vs. 16.6%; p = 0.01). The operative time (212 ± 74 min vs. 243 ± 69 min; p = 0.313) and intraoperative bleeding (268 ± 222 ml vs. 327 ± 169 ml; p = 0.465) were similar in both groups. The conversion rate of the laparoscopic approach to open surgery was 25%. There was no difference in morbidity (41.1 vs. 25%; p = 0.414), although the laparoscopic group had a shorter hospital stay (9 ± 4 days vs. 15 ± 11 days; p = 0.083) without statistical significance.
    Conclusions: The treatment of colovesical fistula by a laparoscopic approach is safe and is associated with less bladder repairs and a shorter hospital stay.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Blood Loss, Surgical ; Female ; Follow-Up Studies ; Humans ; Intestinal Fistula/surgery ; Laparoscopy/methods ; Length of Stay ; Male ; Middle Aged ; Minimally Invasive Surgical Procedures/methods ; Retrospective Studies
    Language English
    Publishing date 2016-11
    Publishing country Mexico
    Document type Comparative Study ; Journal Article
    ZDB-ID 138348-6
    ISSN 0034-8376
    ISSN 0034-8376
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  10. Article ; Online: Presumed bilateral acute retinal necrosis 11 years apart, atypical presentation, and early vitrectomy.

    Navarro-Navarro, Aida / Martinez-Toldos, Jose J / Tarazona-Jaimes, Claudia P / Fernandez-Martinez, Cristian / Baeza-Diaz, Manuel V

    European journal of ophthalmology

    2015  Volume 25, Issue 5, Page(s) e81–3

    Abstract: Purpose: To report a case of presumed bilateral acute retinal necrosis with delayed onset caused by herpes simplex virus type 2, medical treatment, and surgical approach.: Methods: Retrospective, interventional case described in a 51-year-old patient ...

    Abstract Purpose: To report a case of presumed bilateral acute retinal necrosis with delayed onset caused by herpes simplex virus type 2, medical treatment, and surgical approach.
    Methods: Retrospective, interventional case described in a 51-year-old patient who complained of unilateral blurred vision with history of nonoperated retinal detachment in his fellow eye after posterior uveitis 11 years earlier.
    Results: Ocular examination suggested diagnosis of acute retinal necrosis involving the posterior pole and sparing periphery. The causative agent was demonstrated using polymerase chain reaction analysis of the aqueous humor. Intensive medical treatment with intravenous acyclovir, intravitreous foscarnet, and corticosteroids was administered, slowing down but not stopping progression of the disease. Due to the monocular status of the patient and high probability of secondary retinal detachment, early vitrectomy was indicated.
    Conclusions: Rapid and aggressive medical treatment is necessary in this condition. Bilateral involvement often occurs within weeks, but can also happen more rarely after several months or years, requiring long-term follow-up. Early surgical treatment is controversial but it is an option to be considered in certain cases.
    MeSH term(s) Antiviral Agents/therapeutic use ; Combined Modality Therapy ; DNA, Viral/genetics ; Eye Infections, Viral/diagnosis ; Eye Infections, Viral/therapy ; Eye Infections, Viral/virology ; Glucocorticoids/therapeutic use ; Herpes Simplex/diagnosis ; Herpes Simplex/therapy ; Herpes Simplex/virology ; Herpesvirus 2, Human/genetics ; Herpesvirus 2, Human/isolation & purification ; Humans ; Laser Coagulation ; Male ; Middle Aged ; Retinal Necrosis Syndrome, Acute/diagnosis ; Retinal Necrosis Syndrome, Acute/therapy ; Retinal Necrosis Syndrome, Acute/virology ; Retrospective Studies ; Visual Acuity ; Vitrectomy
    Chemical Substances Antiviral Agents ; DNA, Viral ; Glucocorticoids
    Language English
    Publishing date 2015-07-30
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.5301/ejo.5000596
    Database MEDical Literature Analysis and Retrieval System OnLINE

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