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Article: Developing and enhancing promiscuous activity for NAD(P)H-dependent flavin reductase via elimination of cofactor.

Navaser, Amene / Kalhor, Hamid R / Hayati, Fatemeh

Heliyon

2023  Volume 9, Issue 9, Page(s) e19315

Abstract: Promiscuous enzymes have shown their synthetic abilities in generating various organic compounds with high selectively and efficiency under mild conditions. Therefore, the design and development of conditions to raise promiscuity to the enzymes have been ...

Abstract Promiscuous enzymes have shown their synthetic abilities in generating various organic compounds with high selectively and efficiency under mild conditions. Therefore, the design and development of conditions to raise promiscuity to the enzymes have been under the spotlight in recent years. Flavin reductase, that reduces flavins by using NADH as a cofactor, has not been studied in promiscuous reactions. In the present study, it was aimed to develop a catalytic promiscuous activity in the recombinant
Language English
Publishing date 2023-08-25
Publishing country England
Document type Journal Article
ZDB-ID 2835763-2
ISSN 2405-8440
ISSN 2405-8440
DOI 10.1016/j.heliyon.2023.e19315
Database MEDical Literature Analysis and Retrieval System OnLINE

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