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  1. Article ; Online: Benign paraspinal ganglioneuroma with paraneoplastic opsoclonus myoclonus syndrome.

    Prabaharan, Haritha / Chandrasekaran, Suryakala / Shetty, Niharika / Nayak K, Praveen

    BMJ case reports

    2024  Volume 17, Issue 2

    Abstract: Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare immune-mediated movement disorder occurring as a paraneoplastic manifestation of neuroblastic tumours (NTs), especially neuroblastoma in infancy. Ganglioneuroma (GN), the benign tumour in the spectrum, ...

    Abstract Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare immune-mediated movement disorder occurring as a paraneoplastic manifestation of neuroblastic tumours (NTs), especially neuroblastoma in infancy. Ganglioneuroma (GN), the benign tumour in the spectrum, is rarely associated with OMAS. We report the case of a child in her second year of life presenting with acute onset of progressive paraplegia and OMAS. MRI showed diffuse and infiltrating left paraspinal mass from T3-T9 levels with differentials of neuroblastoma or ganglioneuroblastoma. Histopathological and immunohistochemistry examination of the excised tumour showed maturing GN. The OMAS was managed with intravenous immunoglobulin and steroids. In the 6-month follow-up, the child has a residual motor weakness with myelomalacia in neuroimaging. The case report substantiates the occurrence of OMAS as paraneoplastic manifestation in NTs, including benign, in children younger than 2 years with a female predilection.
    MeSH term(s) Child ; Humans ; Female ; Opsoclonus-Myoclonus Syndrome/complications ; Opsoclonus-Myoclonus Syndrome/diagnosis ; Ganglioneuroma/complications ; Ganglioneuroma/diagnosis ; Neuroblastoma/diagnosis ; Ataxia/complications ; Movement
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-256846
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Things We Lost in the Fire: A Conversation "A Tale of Two Extremities".

    Nayak, Kishore / Krishnan, Deepak

    Journal of maxillofacial and oral surgery

    2023  Volume 22, Issue 4, Page(s) 747–748

    Language English
    Publishing date 2023-11-17
    Publishing country India
    Document type Editorial
    ZDB-ID 2502352-4
    ISSN 0974-942X ; 0972-8279
    ISSN (online) 0974-942X
    ISSN 0972-8279
    DOI 10.1007/s12663-023-02060-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Yoga-Nidra as a mental health booster: A narrative review.

    Nayak, Khushboo / Verma, Kedarmal

    Journal of Ayurveda and integrative medicine

    2023  Volume 14, Issue 6, Page(s) 100842

    Abstract: Mental health disorders are treated with all the available advanced health techniques. The pioneers of Indian philosophy, sages, saints, and yogis, through their experiences and rational explanations, expressed the importance of yoga, and their treatment ...

    Abstract Mental health disorders are treated with all the available advanced health techniques. The pioneers of Indian philosophy, sages, saints, and yogis, through their experiences and rational explanations, expressed the importance of yoga, and their treatment effects. Yoga-Nidra (YN), one of a particular forms of yoga, is described as a simple and precise way of dealing with mental disorders. The use of YN as an intervention has been reported to reduce anxiety, anger, depression, post-traumatic stress disorder (PTSD), and other different kinds of psycho-physiological abnormalities. In addition to the role of Yoga-Nidra as an intervention tool, it also brings relaxation to the mind and brain, mental catharsis, a positive attitude, self-improvement, and personality refinement. At the same time, YN contributes to boost concentration, memory, and other cognitive capacities, including attention, and thoughts. Because of its important therapeutic contribution to psychological well-being and mental health, it is currently used as a therapy and medical intervention. Yoga-Nidra and other yogic practices will play an important role in treating mental, physical, and psychological problems and improving cognitive abilities, and will help to connect with oneself.
    Language English
    Publishing date 2023-12-05
    Publishing country United States
    Document type Journal Article
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2023.100842
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  4. Article: Comparative Analysis of Laparoscopic Versus Open Procedures in Specific General Surgical Interventions.

    Patil, Mihir / Gharde, Pankaj / Reddy, Kavyanjali / Nayak, Krushank

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54433

    Abstract: Laparoscopic and open surgeries are two distinct surgical approaches with significantly different procedures and outcomes. Minimally invasive surgery, also known as laparoscopic surgery, utilizes small incisions and specialized instruments like the ... ...

    Abstract Laparoscopic and open surgeries are two distinct surgical approaches with significantly different procedures and outcomes. Minimally invasive surgery, also known as laparoscopic surgery, utilizes small incisions and specialized instruments like the laparoscope to perform procedures. This contrasts with open surgery, which requires larger incisions to directly access the surgical site. Open surgery was the preferred approach for any invasive procedure until the introduction of new technological advances in the form of laparoscopy. While laparoscopy is still evolving, preliminary results demonstrate promise for various operations. Open surgery provides the healthcare professional with more liberty in the form of increased visualization, but it also increases tissue damage and hospital stays. Laparoscopic and open procedures are both valuable surgical methods with advantages and disadvantages. While open surgery is favored for difficult patients, laparoscopic surgery offers a quicker recovery and fewer scars. The choice between the two approaches depends on the patient's condition, surgical demands, and the surgeon's skills. As these methods develop, they become increasingly important for offering safe and efficient surgical treatments across a range of medical specialties.
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Helical Superstructures from the Hierarchical Self-Assembly of Coil-Coil Block Copolymer Guided by Side Chain Amyloid-β(17-19) LVF Peptide.

    Nayak, Kasturee / Sarkar, Niharendra / Bauri, Kamal / De, Priyadarsi

    Biomacromolecules

    2024  Volume 25, Issue 3, Page(s) 1978–1988

    Abstract: The rational design of precisely controlled hierarchical chiral nanostructures from synthetic polymers garnered inspiration from sophisticated biological materials. Since chiral peptide motifs induce helix formation in macromolecules, herein we report ... ...

    Abstract The rational design of precisely controlled hierarchical chiral nanostructures from synthetic polymers garnered inspiration from sophisticated biological materials. Since chiral peptide motifs induce helix formation in macromolecules, herein we report the synthesis of a novel type of hybrid polymer consisting of a β-sheet forming a LVF [L = leucine, V = valine, and F = phenylalanine] tripeptide pendant polymethacrylate block and a poly[poly(ethylene glycol) methyl ether methacrylate] (
    MeSH term(s) Micelles ; Polymers/chemistry ; Polyethylene Glycols/chemistry ; Amyloid beta-Peptides ; Methacrylates
    Chemical Substances Micelles ; Polymers ; polyethylene glycol methacrylate ; Polyethylene Glycols (3WJQ0SDW1A) ; Amyloid beta-Peptides ; Methacrylates
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ISSN 1526-4602
    ISSN (online) 1526-4602
    DOI 10.1021/acs.biomac.3c01379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Conference proceedings ; Online: Weakly nonlinear analysis of rotating magnetoconvection with anisotropic diffusivities in earth’s core near the onset of oscillatory instability

    Yadagiri, R. / Rani, H. / Nayak, K. / Jozef, B.

    XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

    2023  

    Abstract: The influence of anisotropic diffusive coefficients on the stability of the horizontal fluid planar layer, rotating about vertical axis, and permeated by a horizontal homogeneous magnetic field is studied. The linear stability analysis is performed using ...

    Abstract The influence of anisotropic diffusive coefficients on the stability of the horizontal fluid planar layer, rotating about vertical axis, and permeated by a horizontal homogeneous magnetic field is studied. The linear stability analysis is performed using the separable solutions in the form of horizontal rolls. The onset of overstable motions is examined [1] as well as of stationary ones. The weakly nonlinear behaviour of the convective motions in the vicinity of primary instability threshold is studied. The efficiency to transport heat is compared between overstable and stationary modes. References: [1] T. Šoltis, J. Brestenský, (2009), Rotating magnetoconvection with anisotropic diffusivities in the Earth’s core, Physics of the Earth and Planetary Interiors, 178, 27-38.
    Language English
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Book ; Online: Using Genetic Algorithm To Evolve Cellular Automata In Performing Edge Detection

    Nayak, Karan

    2020  

    Abstract: Cellular automata are discrete and computational models thatcan be shown as general models of complexity. They are used in varied applications to derive the generalized behavior of the presented model. In this paper we have took one such application. We ... ...

    Abstract Cellular automata are discrete and computational models thatcan be shown as general models of complexity. They are used in varied applications to derive the generalized behavior of the presented model. In this paper we have took one such application. We have made an effort to perform edge detection on an image using genetic algorithm. The purpose and the intention here is to analyze the capability and performance of the suggested genetic algorithm. Genetic algorithms are used to depict or obtain a general solution of given problem. Using this feature of GA we have tried to evolve the cellular automata and shown that how with time it converges to the desired results.

    Comment: 5 pages
    Keywords Computer Science - Neural and Evolutionary Computing
    Publishing date 2020-05-13
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Surgical Perspectives of Open vs. Laparoscopic Approaches to Lateral Pancreaticojejunostomy: A Comprehensive Review.

    Nayak, Krushank / Shinde, Raju K / Gattani, Rajesh G / Thakor, Tosha

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51769

    Abstract: Pancreaticojejunostomy, a critical step in pancreatic surgery, has significantly evolved surgical approaches, including open, laparoscopic, and robotic techniques. This comprehensive review explores open surgery's historical success, advantages, and ... ...

    Abstract Pancreaticojejunostomy, a critical step in pancreatic surgery, has significantly evolved surgical approaches, including open, laparoscopic, and robotic techniques. This comprehensive review explores open surgery's historical success, advantages, and disadvantages, emphasizing surgeons' accrued experience and familiarity with this approach. However, heightened morbidity and prolonged recovery associated with open pancreaticojejunostomy underscore the need for a nuanced evaluation of alternatives. The advent of robotic-assisted surgery introduces a paradigm shift in pancreatic procedures. Enhanced dexterity, facilitated by wristed instruments, allows intricate suturing and precise tissue manipulation crucial in pancreatic surgery. Three-dimensional visualization augments surgeon perception, improving spatial orientation and anastomotic alignment. Moreover, the potential for a reduced learning curve may enhance accessibility, especially for surgeons transitioning from open techniques. Emerging technologies, including advanced imaging modalities and artificial intelligence, present promising avenues for refining both open and minimally invasive approaches. The ongoing pursuit of optimal outcomes mandates a judicious consideration of surgical techniques, incorporating technological advancements to navigate challenges and enhance patient care in pancreaticojejunostomy.
    Language English
    Publishing date 2024-01-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51769
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The elusive extremities: a case of extramammary Paget disease.

    Radhakrishnan, Shalini / Sreeram, Saraswathy / Nayak, Kashinath / Reddy, Sai Goutham

    BMJ case reports

    2024  Volume 17, Issue 1

    Abstract: Extramammary Paget disease is a rare dermatological condition resembling Paget disease that occurs most commonly in the anogenital area and axilla. We present the case of an elderly male who had come with complaints of an itchy, erythematous and raised ... ...

    Abstract Extramammary Paget disease is a rare dermatological condition resembling Paget disease that occurs most commonly in the anogenital area and axilla. We present the case of an elderly male who had come with complaints of an itchy, erythematous and raised lesion in the perianal region for 3 months that did not respond to antifungals. A biopsy was taken from the lesion site and the diagnosis was confirmed by histopathological examination. It is important to be aware of conditions like extramammary Paget disease when an elderly individual presents with a non-specific pruritic lesion in the perianal area that is non-responsive to treatment; the diagnosis of which can be made only by doing a biopsy from the concerned site. This highlights the importance of histopathological examination in such ambiguous cases.
    MeSH term(s) Aged ; Humans ; Male ; Paget Disease, Extramammary/diagnosis ; Extremities ; Antifungal Agents ; Awareness ; Axilla ; Rare Diseases
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-258045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effect of targeted intervention on C-terminal agrin fragment and its association with the components of sarcopenia: a scoping review.

    Kumar, Prabal / Nayak, Kusumakshi / Umakanth, Shashikiran / Girish, N

    Aging clinical and experimental research

    2023  Volume 35, Issue 6, Page(s) 1161–1186

    Abstract: Background: C-terminal Agrin Fragment (CAF) has emerged as a potent biomarker for identifying sarcopenia. However, the effect of interventions on CAF concentration and the association of CAF with sarcopenia components are unclear.: Objective: To ... ...

    Abstract Background: C-terminal Agrin Fragment (CAF) has emerged as a potent biomarker for identifying sarcopenia. However, the effect of interventions on CAF concentration and the association of CAF with sarcopenia components are unclear.
    Objective: To review the association between CAF concentration and muscle mass, muscle strength, and physical performance among individuals with primary and secondary sarcopenia and to synthesize the effect of interventions on the change in the level of CAF concentration.
    Methods: A systematic literature search was conducted in six electronic databases, and studies were included if they met the selection criteria decided a priori. The data extraction sheet was prepared, validated, and extracted relevant data.
    Results: A total of 5,158 records were found, of which 16 were included. Among studies conducted on individuals with primary sarcopenia, muscle mass was significantly associated with CAF levels, followed by hand grip strength (HGS) and physical performance, with more consistent findings in males. While in secondary sarcopenics, the strongest association was found for HGS and CAF levels, followed by physical performance and muscle mass. CAF concentration was reduced in trials that used functional, dual task, and power training, whereas resistance training and physical activity raised CAF levels. Hormonal therapy did not affect serum CAF concentration.
    Conclusion(s): The association between CAF and sarcopenic assessment parameters varies in primary and secondary sarcopenics. The findings would help practitioners and researchers choose the best training mode/parameters/exercises to reduce CAF levels and, eventually, manage sarcopenia.
    MeSH term(s) Humans ; Male ; Agrin ; Hand Strength/physiology ; Muscle Strength ; Sarcopenia
    Chemical Substances Agrin ; C-terminal agrin fragment
    Language English
    Publishing date 2023-03-28
    Publishing country Germany
    Document type Journal Article ; Systematic Review
    ZDB-ID 2104785-6
    ISSN 1720-8319 ; 1594-0667
    ISSN (online) 1720-8319
    ISSN 1594-0667
    DOI 10.1007/s40520-023-02396-w
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