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Article ; Online: Bis(1-methylimidazol-2-yl) diselenide and its evaluation as a chemical radio-protector: role of kinetic rate constants for ROS scavenging and glutathione peroxidase like activity.

Makhijani, K / Kumbhare, L B / Nayak, M / Kunwar, A / Singh, B G

2024 Volume 58, Issue 1, Page(s) 43–56

Abstract: Bis(1-methylimidazol-2-yl) diselenide (MeImSe), a derivative of selenoneine, has been examined for bimolecular rate constants for scavenging of various radiolytically and non-radiolytically generated reactive oxygen species (ROS). Further, its potential ... ...

Abstract	Bis(1-methylimidazol-2-yl) diselenide (MeImSe), a derivative of selenoneine, has been examined for bimolecular rate constants for scavenging of various radiolytically and non-radiolytically generated reactive oxygen species (ROS). Further, its potential to show glutathione peroxidase (GPx)-like activity and to protect
MeSH term(s)	Humans ; Antioxidants/metabolism ; Reactive Oxygen Species/metabolism ; Glutathione Peroxidase/metabolism ; Nitrogen Dioxide ; Organoselenium Compounds/chemistry ; Lipid Peroxidation ; DNA/metabolism ; Oxidants ; Lipids ; Oxidation-Reduction ; Histidine/analogs & derivatives
Chemical Substances	Antioxidants ; Reactive Oxygen Species ; selenoneine ; Glutathione Peroxidase (EC 1.11.1.9) ; Nitrogen Dioxide (S7G510RUBH) ; Organoselenium Compounds ; DNA (9007-49-2) ; Oxidants ; Lipids ; Histidine (4QD397987E)
Language	English
Publishing date	2024-02-07
Publishing country	England
Document type	Journal Article
ZDB-ID	1194130-3
ISSN	1029-2470 ; 1071-5762
ISSN (online)	1029-2470
ISSN	1071-5762
DOI	10.1080/10715762.2023.2299341
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Article: History of Cosmetic in Egypt, India, and China.

Nayak, Manjula / Ligade, Virendra S

Journal of cosmetic science

2022 Volume 72, Issue 4, Page(s) 432–441

Abstract: Cosmetics are preparations used to improve and enhance human appearance. The concept of beauty and cosmetics is as ancient as mankind and civilization. The use of plants and herbs for cosmetics was started in ancient times. Egyptians believed that ... ...

Abstract	Cosmetics are preparations used to improve and enhance human appearance. The concept of beauty and cosmetics is as ancient as mankind and civilization. The use of plants and herbs for cosmetics was started in ancient times. Egyptians believed that healing plants possess supernatural power. Herbs used for cosmetics in China are popular and are biologically active in today's cosmetics. The most commonly used herb, as a cosmetic in India, is turmeric, which is still in use as the beauty routine before the wedding. In Egypt, around 10,000 BCE both men and women were using scented oils and ointments to clean their skin and mask body odor. The use of cosmetics in India dates backs to the Vedic and Puranic periods. Due to the increased consciousness about beauty, demand for the products is increasing, which results in the growth of the cosmetic industry.
MeSH term(s)	China ; Cosmetics ; Egypt ; Female ; Humans ; India ; Skin
Chemical Substances	Cosmetics
Language	English
Publishing date	2022-03-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1435667-3
ISSN	1525-7886 ; 0037-9832
ISSN	1525-7886 ; 0037-9832
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Zs.A 3474: Show issues

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Article ; Online: Perceptions through artwork: children’s understanding of elephants and human-elephant interactions in Balasore, India

Nayak, Medha / Swain, Pranaya Kumar

Human Dimensions of Wildlife. 2022 Nov. 02, v. 27, no. 6 p.592-601

2022

Abstract: Several studies have analyzed perceptions of adults regarding human-elephant conflict, but only a few have considered children as stakeholders. This research note attempted to understand young stakeholder perspectives about elephants for the purpose of ... ...

Abstract	Several studies have analyzed perceptions of adults regarding human-elephant conflict, but only a few have considered children as stakeholders. This research note attempted to understand young stakeholder perspectives about elephants for the purpose of proposing appropriate and contextual tools of conservation education and favorable human-elephant interactions. The study employed a draw-and-write method with 47 teenaged children from villages near a migratory corridor in the Balasore district of Odisha state in India. Through content analysis of the artworks, several references to negative interactions between humans and elephants (e.g., elephants raiding crops, damaging houses, and breaking trees; elephants and humans inflicting injuries on each other), vulnerability indicators, and community responses were noticed. The gender of participants also emerged as a significant factor in the production of different perceptions. Elephant tuskers engaging in hostile activities and people chasing elephants were mostly depicted by boys, whereas girls illustrated people watching helplessly or guarding property.
Keywords	education ; gender ; humans ; migratory behavior ; stakeholders ; wildlife ; India ; Human-elephant conflict ; conservation education ; coexistence ; drawing ; children
Language	English
Dates of publication	2022-1102
Size	p. 592-601.
Publishing place	Routledge
Document type	Article ; Online
ISSN	1533-158X
DOI	10.1080/10871209.2021.1985659
Database	NAL-Catalogue (AGRICOLA)

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Article: Management of Neglected Patellar Tendon Rupture by Peroneus Longus Autograft and Suture Anchor: A Case Report.

Patra, Saroj Kumar / Nayak, Manmatha / Patro, Bishnu Prasad

Journal of orthopaedic case reports

2023 Volume 12, Issue 11, Page(s) 5–8

Abstract: Introduction: Patellar tendon rupture is a rare injury and is often missed in primary and secondary care centers because of non-visibility in X-rays. Neglected rupture is even rarer and gives rise to significant disability. These injuries are ... ...

Abstract	Introduction: Patellar tendon rupture is a rare injury and is often missed in primary and secondary care centers because of non-visibility in X-rays. Neglected rupture is even rarer and gives rise to significant disability. These injuries are technically difficult to repair with invariably poor functional outcomes. This needs reconstruction with allograft or autograft with or without augmentation. We report such a case of neglected patellar tendon injury treated with peroneus longus autograft. Case report: A 37-year-old male patient presented with limping and inability to do a full extension of the knee. There is a history of a lacerated wound over the knee following a bike accident. Reconstruction was done with peroneus longus auto graft by making a trans-osseous tunnel through the patella and tibial tuberosity in the Figure eight 8 manner and fixed by a suture anchor. Postoperatively, the patient was doing well at a 1-year follow-up. Conclusion: Good clinical outcomes can be achieved in neglected patellar tendon rupture by auto graft without augmentation.
Language	English
Publishing date	2023-01-17
Publishing country	India
Document type	Case Reports
ZDB-ID	2658169-3
ISSN	2250-0685
ISSN	2250-0685
DOI	10.13107/jocr.2022.v12.i11.3392
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Article: Chondromyxoid Fibroma of a Rib.

Sathia, Siddhartha / Jain, Mantu / Nayak, Manmatha / Purkait, Suvendu

Journal of orthopaedic case reports

2023 Volume 13, Issue 1, Page(s) 92–95

Abstract: Introduction: Chondromyxoid fibroma (CMF) is an uncommon bone tumor, accounting for <1% of all bone tumors. It generally affects the metaphysis of the long bone of the lower limb and seldom involves the small bones, but the involvement of the flat bones, ...

Abstract	Introduction: Chondromyxoid fibroma (CMF) is an uncommon bone tumor, accounting for <1% of all bone tumors. It generally affects the metaphysis of the long bone of the lower limb and seldom involves the small bones, but the involvement of the flat bones, like ribs, is infrequent. Case report: A teenage girl complained of pain on the right side of the chest for the past 6 months, dull aching, and persistent without any diurnal variation. The chest X-ray examination showed a nodular, hyperdense lesion on the lateral chest wall near the 5-7th rib on the right side. A computed tomography scan confirmed the lesion from the sixth rib with ground-glass matrix and cortical thinning with a smooth margin, without any soft-tissue involvement. An enblock excision of the lesion was done. Histopathological studies showed a well-circumscribed tumor with reactive bone formation at the periphery with lobules of chondromyxoid tissue separated by spindle cells and stellate-shaped cells suggestive of CMF. At 1-year follow-up, she is asymptomatic without any recurrence. Conclusion: CMFs are rare benign tumors that require histopathological study to differentiate from other benign lesions of the bone. In flat tubular bones like the ribs, enblock resection is the mainstay of treatment.
Language	English
Publishing date	2023-04-18
Publishing country	India
Document type	Case Reports
ZDB-ID	2658169-3
ISSN	2250-0685
ISSN	2250-0685
DOI	10.13107/jocr.2023.v13.i01.3528
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Awareness level regarding adverse reactions caused by cosmetic products among female patients: A cross-sectional study.

Nayak, Manjula / Ligade, Virendra S / Prabhu, Smitha S

Journal of cosmetic dermatology

2023 Volume 22, Issue 9, Page(s) 2512–2519

Abstract: Background: Cosmetics have become an integral part of our daily routine. In addition to causing a wide range of dermatological disorders, cosmetic preparations can also affect internal health. Men are less likely to be impacted than women.: Objective!# ...

Abstract	Background: Cosmetics have become an integral part of our daily routine. In addition to causing a wide range of dermatological disorders, cosmetic preparations can also affect internal health. Men are less likely to be impacted than women. Objective: This study aimed at determining the awareness level among female patients regarding adverse reactions caused by cosmetic products. Method: A cross-sectional study was performed among women who visited the Dermatology department of Kasturba Hospital, Manipal, Karnataka, from December 2020 to March 2022. The sample size included 400 respondents selected using the Convenience sampling method, and data were collected using a self-administered questionnaire. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 21, and descriptive statistics were applied. Results: The study found that many cosmetic users experienced negative side effects (44%). The primarily affected body site was the face (25.50%) followed by scalp and hair (10%). Products responsible for adverse events were skin care products (27.25%). Considerable percentage of patients self-medicated (22.25%) and only 15% of women consulted a dermatologist for cosmetic-related problems. Conclusion: Awareness regarding the possibility of cosmetic-induced adverse effects as well as the proper use of cosmetics to reduce these adverse effects is imperative. Implementation of cosmetovigilance system will help to decrease the adverse events to a certain extent.
MeSH term(s)	Male ; Humans ; Female ; Cross-Sectional Studies ; India ; Cosmetics/adverse effects ; Surveys and Questionnaires ; Hair
Chemical Substances	Cosmetics
Language	English
Publishing date	2023-03-31
Publishing country	England
Document type	Journal Article
ZDB-ID	2280551-5
ISSN	1473-2165 ; 1473-2130
ISSN (online)	1473-2165
ISSN	1473-2130
DOI	10.1111/jocd.15734
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Zs.A 6539: Show issues

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Article ; Online: Exploring the reprogramming potential of B cells and comprehending its clinical and therapeutic perspective.

Rani, Reetika / Nayak, Madhusmita / Nayak, Bismita

Transplant immunology

2023 Volume 78, Page(s) 101804

Abstract: Initiating from multipotent progenitors, the lineages extrapolated from hematopoietic stem cells are determined by transcription factors specific to each of them. The commitment factors assist in the differentiation of progenitor cells into terminally ... ...

Abstract	Initiating from multipotent progenitors, the lineages extrapolated from hematopoietic stem cells are determined by transcription factors specific to each of them. The commitment factors assist in the differentiation of progenitor cells into terminally differentiated cells. B lymphocytes constitute a population of cells that expresses clonally diverse cell surface immunoglobulin (Ig) receptors specific to antigenic epitopes. B cells are a significant facet of the adaptive immune system. The secreted antibodies corresponding to the B cell recognize the antigens via the B cell receptor (BCR). Following antigen recognition, the B cell is activated and thereafter undergoes clonal expansion and proliferation to become memory B cells. The essence of 'cellular reprogramming' has aided in reliably altering the cells to desired tissue type. The potential of reprogramming has been harnessed to decipher and find solutions for various genetically inherited diseases and degenerative disorders. B lymphocytes can be reprogrammed to their initial naive state from where they get differentiated into any lineage or cell type similar to a pluripotent stem cell which can be accomplished by the deletion of master regulators of the B cell lineage. B cells can be reprogrammed into pluripotent stem cells and also can undergo transdifferentiation at the midway of cell differentiation to other cell types. Mandated expression of C/EBP in specialized B cells corresponds to their fast and effective reprogramming into macrophages, reversing the cell fate of these lymphocytes and allowing them to differentiate freshly into other types of cells. The co-expression of C/EBPα and OKSM (Oct4, Sox2, Klf4, c-Myc) amplified the reprogramming efficiency of B lymphocytes. Various human somatic cells including the immune cells are compliant to reprogramming which paves a path for opportunities like autologous tissue grafts, blood transfusion, and cancer immunotherapy. The ability to reprogram B cells offers an unprecedented opportunity for developing a therapeutic approach for several human diseases. Here, we will focus on all the proteins and transcription factors responsible for the developmental commitment of B lymphocytes and how it is harnessed in various applications.
MeSH term(s)	Humans ; Cellular Reprogramming ; Cell Differentiation ; Pluripotent Stem Cells ; Transcription Factors/genetics ; B-Lymphocytes
Chemical Substances	Transcription Factors
Language	English
Publishing date	2023-03-13
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	1160846-8
ISSN	1878-5492 ; 0966-3274
ISSN (online)	1878-5492
ISSN	0966-3274
DOI	10.1016/j.trim.2023.101804
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Zs.A 3784: Show issues

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Article ; Online: Adsorption of Selenium and Lanthanum by Agrobacterium-mediated Hairy Roots of Hybanthus Enneaspermus (L.) F. Muell: A Greener Phytoremediation Strategy.

Mohanty, Roshnara / Nayak, Manoranjan / Sekar, Thangavel / Thirunavoukkarasu, Manikkannan

Bulletin of environmental contamination and toxicology

2023 Volume 110, Issue 2, Page(s) 54

Abstract: In this study, phytoremediation potential of toxic metals like selenium (Se) and lanthanum (La) by transformed hairy roots was investigated and compared with plantlets under in-vitro conditions. Agrobacterium rhizogenes A4RS could induce hairy roots with ...

Abstract	In this study, phytoremediation potential of toxic metals like selenium (Se) and lanthanum (La) by transformed hairy roots was investigated and compared with plantlets under in-vitro conditions. Agrobacterium rhizogenes A4RS could induce hairy roots with higher biomass in 5-7 days of infection on in-vitro leaves of Hybanthus enneaspermus. The ICP-OES data indicated that the hairy roots were able to accumulate both selenium and lanthanum efficiently compared to plantlets. The hairy roots and plantlets show optimum absorption at 50 ppm under both individual and combined metal supply. The metal accumulation performances increased by 13.6% (La) and 10.9% (Se) in hairy roots with combined metal supply (La and Se) compared to individual supply (La or Se) conditions. The Se accumulated more than La, but the La accumulation percentage was found to increase substantially under combined metal supply conditions, shows the suitability and potential of hairy roots for phytoremediation of La and Se.
MeSH term(s)	Plants, Genetically Modified ; Selenium ; Lanthanum ; Adsorption ; Biodegradation, Environmental ; Plant Roots/microbiology ; Agrobacterium/genetics ; Violaceae
Chemical Substances	Selenium (H6241UJ22B) ; Lanthanum (6I3K30563S)
Language	English
Publishing date	2023-02-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	6895-0
ISSN	1432-0800 ; 0007-4861
ISSN (online)	1432-0800
ISSN	0007-4861
DOI	10.1007/s00128-023-03694-9
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Article ; Online: Recent advances of nanocrystals in cancer theranostics.

Yenurkar, Devyani / Nayak, Malay / Mukherjee, Sudip

Nanoscale advances

2023 Volume 5, Issue 16, Page(s) 4018–4040

Abstract: Emerging cancer cases across the globe and treating them with conventional therapies with multiple limitations have been challenging for decades. Novel drug delivery systems and alternative theranostics are required for efficient detection and treatment. ...

Abstract	Emerging cancer cases across the globe and treating them with conventional therapies with multiple limitations have been challenging for decades. Novel drug delivery systems and alternative theranostics are required for efficient detection and treatment. Nanocrystals (NCs) have been established as a significant cancer diagnosis and therapeutic tool due to their ability to deliver poorly water-soluble drugs with sustained release, low toxicity, and flexibility in the route of administration, long-term sustainable drug release, and noncomplicated excretion. This review summarizes several therapies of NCs, including anticancer, immunotherapy, radiotherapy, biotheranostics, targeted therapy, photothermal, and photodynamic. Further, different imaging and diagnostics using NCs are mentioned, including imaging, diagnosis through magnetic resonance imaging (MRI), computed tomography (CT), biosensing, and luminescence. In addition, the limitations and potential solutions of NCs in the field of cancer theranostics are discussed. Preclinical and clinical data depicting the importance of NCs in the spotlight of cancer, its current status, future aspects, and challenges are covered in detail.
Language	English
Publishing date	2023-07-10
Publishing country	England
Document type	Journal Article ; Review
ISSN	2516-0230
ISSN (online)	2516-0230
DOI	10.1039/d3na00397c
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Radiological Features and Management of Intracranial Aneurysms Associated With Moyamoya Disease: A Case Series of Single-Center Experience.

Phuyal, Subash / Gaikwad, Shailesh B / Garg, Ajay / Jain, Nishchint / Nayak, Manoj / Devarajan, Leve J

Cureus

2024 Volume 16, Issue 1, Page(s) e52370

Abstract: Background Moyamoya disease (MMD) can be a major cause of hemorrhagic stroke. Though extensive angiographic studies have been undertaken, the understanding of the association between aneurysms and MMD remains unanswered. In this study, we explore the ... ...

Abstract	Background Moyamoya disease (MMD) can be a major cause of hemorrhagic stroke. Though extensive angiographic studies have been undertaken, the understanding of the association between aneurysms and MMD remains unanswered. In this study, we explore the association of the aneurysm with MMD and its management. We have also reviewed such associations described in the literature and how the present cases differ from those previously described. Materials and methods The clinical and radiologic data of moyamoya disease cases were accessed from medical and radiological records between January 2010 and July 2017. Two neuroradiologists independently analyzed the data and imaging details. Results Out of 103 patients with MMD, eight patients (7.77%) had associated intracranial aneurysms with eleven aneurysms. Out of the 11 aneurysms, five were the tip of the basilar artery aneurysms and were the most common location for aneurysm (45.5%), followed by lenticulostriate artery, PCA perforator, and distal ACA (DACA) in the P1 PCA, P2 PCA, and P3 PCA artery aneurysms. Out of eight patients, five (62.5%) had a hemorrhage on a non-contrast computed tomography (NCCT) scan of the brain, whereas three (37.5%) had an ischemic presentation. Out of 11 aneurysms, seven aneurysms, including three basilar tip aneurysms (unruptured) and one PCA perforator (ruptured), and three saccular PCA (P1, P2, and P3) (ruptured) were treated by endovascular coiling. Follow-up angiography showed stable aneurysmal occlusion except in one basilar tip, where recurrence was observed. Conclusions MMD-intracranial aneurysm is commonly observed in patients with intracranial hemorrhage and carries a higher risk of rupture. Therefore, identification of the aneurysm is essential for management. Endovascular treatment, either with coil or glue embolization, can be a safe and effective treatment method for such aneurysms with long-term good results.
Language	English
Publishing date	2024-01-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.52370
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