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  1. Article ; Online: Synopsis of JBS recommendations for magnetic resonance imaging in patients with cardiac implantable electronic devices.

    Zghaib, Tarek / Nazarian, Saman

    Heart (British Cardiac Society)

    2024  Volume 110, Issue 4, Page(s) 225–227

    MeSH term(s) Humans ; Magnetic Resonance Imaging/methods ; Defibrillators, Implantable ; Heart ; Pacemaker, Artificial
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2022-321480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Volume-Weighted Unipolar Voltage: A Novel Prognostic Marker in Dilated Cardiomyopathy and Ventricular Arrhythmia.

    Zghaib, Tarek / Nazarian, Saman

    JACC. Clinical electrophysiology

    2023  Volume 9, Issue 7 Pt 1, Page(s) 976–978

    MeSH term(s) Humans ; Cardiomyopathy, Dilated/complications ; Cardiomyopathy, Dilated/diagnosis ; Prognosis ; Arrhythmias, Cardiac/diagnosis
    Language English
    Publishing date 2023-03-22
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2023.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Expression and purification of TolC as a recombinant protein vaccine against Shigella flexneri and evaluation of immunogenic response in mice.

    Veisi, Razieh / Nazarian, Shahram / Fathi, Javad / Hadi, Nahal

    Microbial pathogenesis

    2024  Volume 188, Page(s) 106539

    Abstract: Background: Shigella is one of the major causes of dysenteric diarrhea, which is known shigelosis. Shigelosis causes 160,000 deaths annually of diarrheal disease in the global scale especially children less than 5 years old. No licensed vaccine is ... ...

    Abstract Background: Shigella is one of the major causes of dysenteric diarrhea, which is known shigelosis. Shigelosis causes 160,000 deaths annually of diarrheal disease in the global scale especially children less than 5 years old. No licensed vaccine is available against shigelosis, therefore, efforts for develop an effective and safe vaccine against Shigella as before needed. The reverse vaccinology (RV) is a novel strategy that evaluate genome or proteome of the organism to find a new promising vaccine candidate. In this study, immunogenicity of a designed-recombinant antigen is evaluated through the in silico studies and animal experiments to predict a new immunogenic candidate against Shigella.
    Methods: In the first step, proteome of Shigella flexneri was obtained from UniProtKB and then the outer membrane and extracellular proteins were predicted. In this study TolC as an outer membrane protein was selected and confirmed among candidates. In next steps, pre-selected protein was evaluated for transmembrane domains, homology, conservation, antigenicity, solubility, and B- and T-cell prediction by different online servers.
    Result: TolC as a conserved outer membrane protein, using different immune-informatics tools had acceptable scores and was selected as the immunogenic antigen for animal experiment studies. Recombinant TolC protein after expression and purification, was administered to BALB/c mice over three intraperitoneal routes. The sera of mice was used to evaluate the IgG1 production assay by indirect-ELISA. The immunized mice depicted effective protection against 2LD
    Conclusion: Therefore, the reverse vaccinology approach and experimental test results demonstrated that TolC as a novel effective and immunogenic antigen is capable for protection against shigellosis.
    MeSH term(s) Humans ; Child ; Animals ; Mice ; Child, Preschool ; Shigella flexneri/genetics ; Protein Subunit Vaccines ; Shigella Vaccines/genetics ; Proteome ; Shigella ; Dysentery, Bacillary/prevention & control ; Recombinant Proteins/genetics ; Vaccines, Synthetic/genetics ; Membrane Proteins ; Antibodies, Bacterial
    Chemical Substances Protein Subunit Vaccines ; Shigella Vaccines ; Proteome ; Recombinant Proteins ; Vaccines, Synthetic ; Membrane Proteins ; Antibodies, Bacterial
    Language English
    Publishing date 2024-01-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2024.106539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Practice Problems for Hardware Engineers

    Nazarian, Shahin

    2021  

    Abstract: This book is to help undergraduate and graduate students of electrical and computer engineering disciplines with their job interviews. It may also be used as a practice resource while taking courses in VLSI, logic and computer architecture design. The ... ...

    Abstract This book is to help undergraduate and graduate students of electrical and computer engineering disciplines with their job interviews. It may also be used as a practice resource while taking courses in VLSI, logic and computer architecture design. The first edition consists of more than 150 problems and their solutions which the author has used in his VLSI, logic, and architectures courses while teaching at USC. The author wishes this book to be available free of charge, subject to the copyright policy on page 3.

    Comment: 166 pages, Kindle Direct Publishing, Amazon 1st Edition
    Keywords Computer Science - Hardware Architecture ; B.0
    Publishing date 2021-10-13
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Sarcoid heart disease and imaging.

    Tan, Jian Liang / Supple, Gregory E / Nazarian, Saman

    Heart rhythm O2

    2023  Volume 5, Issue 1, Page(s) 50–59

    Abstract: Cardiac sarcoidosis (CS) can mimic any cardiomyopathy due to its ability to manifest with a variety of clinical presentations. The exact prevalence of CS remains unknown but has been reported ranging from 2.3% to as high as 29.9% among patients ... ...

    Abstract Cardiac sarcoidosis (CS) can mimic any cardiomyopathy due to its ability to manifest with a variety of clinical presentations. The exact prevalence of CS remains unknown but has been reported ranging from 2.3% to as high as 29.9% among patients presenting with new onset cardiomyopathy and/or atrioventricular block. Early and accurate diagnosis of CS is often challenging due to the nature of disease progression and lack of diagnostic reference standard. The current diagnostic criteria for CS are lacking in sensitivity and specificity. Here, we review the contemporary role of advanced imaging modalities such as cardiac magnetic resonance imaging and positron emission tomography/computed tomography imaging in diagnosing and prognosticating patients with CS.
    Language English
    Publishing date 2023-11-19
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2666-5018
    ISSN (online) 2666-5018
    DOI 10.1016/j.hroo.2023.11.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: GAHLS: an optimized graph analytics based high level synthesis framework.

    Xiao, Yao / Nazarian, Shahin / Bogdan, Paul

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 22655

    Abstract: The urgent need for low latency, high-compute and low power on-board intelligence in autonomous systems, cyber-physical systems, robotics, edge computing, evolvable computing, and complex data science calls for determining the optimal amount and type of ... ...

    Abstract The urgent need for low latency, high-compute and low power on-board intelligence in autonomous systems, cyber-physical systems, robotics, edge computing, evolvable computing, and complex data science calls for determining the optimal amount and type of specialized hardware together with reconfigurability capabilities. With these goals in mind, we propose a novel comprehensive graph analytics based high level synthesis (GAHLS) framework that efficiently analyzes complex high level programs through a combined compiler-based approach and graph theoretic optimization and synthesizes them into message passing domain-specific accelerators. This GAHLS framework first constructs a compiler-assisted dependency graph (CaDG) from low level virtual machine (LLVM) intermediate representation (IR) of high level programs and converts it into a hardware friendly description representation. Next, the GAHLS framework performs a memory design space exploration while account for the identified computational properties from the CaDG and optimizing the system performance for higher bandwidth. The GAHLS framework also performs a robust optimization to identify the CaDG subgraphs with similar computational structures and aggregate them into intelligent processing clusters in order to optimize the usage of underlying hardware resources. Finally, the GAHLS framework synthesizes this compressed specialized CaDG into processing elements while optimizing the system performance and area metrics. Evaluations of the GAHLS framework on several real-life applications (e.g., deep learning, brain machine interfaces) demonstrate that it provides 14.27× performance improvements compared to state-of-the-art approaches such as LegUp 6.2.
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-48981-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Using Diffuse Reflectance Spectroscopy to Classify Tumor Tissue in Upper Gastrointestinal Cancers-Reply.

    Nazarian, Scarlet / Gkouzionis, Ioannis / Peters, Christopher J

    JAMA surgery

    2023  Volume 158, Issue 7, Page(s) 773

    MeSH term(s) Humans ; Spectrum Analysis/methods ; Gastrointestinal Neoplasms/diagnosis
    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2022.8433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comments on "Advertising on Social Media: The Plastic Surgeon's Prerogative".

    Nazarian, Sheila

    Aesthetic surgery journal

    2017  Volume 37, Issue 2, Page(s) NP20–NP21

    MeSH term(s) Advertising as Topic ; Humans ; Social Media ; Surgeons ; Surgery, Plastic
    Language English
    Publishing date 2017
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjw201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Right Ventricular Dysfunction: An Ominous Sign.

    Nazarian, Saman / Zghaib, Tarek

    Radiology

    2021  Volume 301, Issue 2, Page(s) 330–331

    MeSH term(s) Heart Ventricles/diagnostic imaging ; Humans ; Pulmonary Embolism ; Ventricular Dysfunction, Right/diagnostic imaging
    Language English
    Publishing date 2021-08-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2021211383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Distinguishing Tachycardia Mediated From Structural Cardiomyopathy: Association of Late Gadolinium Enhancement With Recovery of Ventricular Systolic Function Following Atrial Fibrillation Ablation.

    Nazarian, Saman

    Journal of the American Heart Association

    2016  Volume 5, Issue 9

    Language English
    Publishing date 2016-09-26
    Publishing country England
    Document type Editorial
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.116.003292
    Database MEDical Literature Analysis and Retrieval System OnLINE

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