Article: Medication Management Program: Adherence, Disease-related Knowledge, Health-related Quality of Life, and Glycemic Control for Type 2 Diabetes Mellitus.
Alternative therapies in health and medicine
2019 Volume 26, Issue S2, Page(s) 4–10
Abstract: Context: Escalation in rates of diabetes in Pakistan is posing threats to the economy and to the people's quality of life due to poor glycemic control and very high rates of complications. Cost of care is very high, and many barriers to quality care ... ...
Abstract | Context: Escalation in rates of diabetes in Pakistan is posing threats to the economy and to the people's quality of life due to poor glycemic control and very high rates of complications. Cost of care is very high, and many barriers to quality care exist. Most often patients are unable to afford the high cost of treatment. Patients' knowledge about diabetes is associated with better medication adherence and better glycemic control. Objective: The current study intended to evaluate the effects of an educational intervention in a pharmacist led, medication management program (MTM) tailored for patients with type 2 diabetes (T2DM). Design: The research team conducted a nonclinical, randomized controlled trial. Setting: The study took place at District Headquarters and Teaching Hospital, a public-sector hospital (Sargodha, Pakistan). Participants: Participants were 392 individuals with T2DM. Intervention: Participants were randomly assigned to one of 2 groups-intervention and control-with 196 patients in each. The intervention group, instead of receiving standard care, received pharmaceutical care through the Medication Therapy Management program, whereas the control group received standard care. Outcome measures: At baseline and 3 mo post ntervention, the study assessed participants' diabetes-related knowledge, medication adherence, and health-related quality of life (HRQoL) using the 14-item Michigan Diabetes Knowledge Test, the 8-item Morisky Medication Adherence Scale, and the European Quality of Life scales, respectively. To determine glycemic control, participants' baseline HbA1c levels were taken from their medical records, and the final HbA1c result was obtained postintervention. Results: For the intervention and control groups at baseline, diabetes-related knowledge was average, at 7.99 ± 2.65 and 8.03 ± 2.49, respectively; medication adherence was low, at 4.54 ± 1.69 and 4.41 ± 1.84, respectively; and glycemic control was poor, at 9.47 ± 1.57 and 9.41 ± 1.57, respectively. After the educational intervention, the intervention group had increased its diabetes-related knowledge, medication adherence, and HRQoL scores, with the results being 10.55 ± 2.56, 5.24 ± 1.48, and 0.6115 ± 0.286, respectively. The group's glycemic control has also improved to 8.97 ± 1.362. A statistically significant difference between the groups had occurred, with P < .001. The control group's scores had remained approximately the same for medication adherence, HRQoL, and glycemic control, and little difference had occurred as compared with the group's baseline analysis. Conclusion: The study found that the educational program increased the intervention group's level of diabetes-related knowledge, and improved its adherence to medication and its glycemic control, all due to its improved HRQoL. Patients' beliefs about the effects of long-term use of medicines were also addressed by the MTM program. The program was successful because it decreased participants' HbA1c values, which is a positive indicator of successful T2DM therapy. |
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MeSH term(s) | Adult ; Blood Glucose ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/psychology ; Glycated Hemoglobin A/metabolism ; Health Care Surveys ; Health Knowledge, Attitudes, Practice ; Humans ; Hypoglycemic Agents/therapeutic use ; Medication Adherence ; Medication Therapy Management ; Pakistan ; Patient Education as Topic ; Quality of Life/psychology ; Treatment Outcome |
Chemical Substances | Blood Glucose ; Glycated Hemoglobin A ; Hypoglycemic Agents |
Language | English |
Publishing date | 2019-10-21 |
Publishing country | United States |
Document type | Journal Article ; Randomized Controlled Trial |
ZDB-ID | 1225073-9 |
ISSN | 1078-6791 |
ISSN | 1078-6791 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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