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  1. Article ; Online: Localized malignant pleural mesothelioma of the interlobar fissure mimicking a lung cancer.

    Ciriaco, Paola / Viscardi, Stefano / Filipello, Federica / Negri, Giampiero

    Interactive cardiovascular and thoracic surgery

    2021  Volume 34, Issue 4, Page(s) 700–702

    Abstract: We report a case of localized malignant pleural mesothelioma (LMPM) of the interlobar fissure mimicking lung cancer. A 74-year-old woman presented with dyspnoea and a left pleural effusion. Chest computed tomography revealed a bulky mass, arising from ... ...

    Abstract We report a case of localized malignant pleural mesothelioma (LMPM) of the interlobar fissure mimicking lung cancer. A 74-year-old woman presented with dyspnoea and a left pleural effusion. Chest computed tomography revealed a bulky mass, arising from the left lower lobe with intense uptake at the 18F-FDG PET. A left lower lobectomy was performed after thoracoscopic pleural biopsies. The final histology revealed an LMPM epithelioid like. We describe the diagnostic and curative path of the disease, speculating on the differential diagnosis and treatment of LMPM.
    MeSH term(s) Aged ; Female ; Humans ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Mesothelioma/diagnostic imaging ; Mesothelioma/surgery ; Mesothelioma, Malignant ; Pleura/pathology ; Pleural Neoplasms/diagnostic imaging ; Pleural Neoplasms/surgery
    Language English
    Publishing date 2021-11-18
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2095298-3
    ISSN 1569-9285 ; 1569-9293
    ISSN (online) 1569-9285
    ISSN 1569-9293
    DOI 10.1093/icvts/ivab307
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5730: Show issues Location:
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  2. Article ; Online: An unusual case of a posterior mediastinal myelolipoma in a patient with mediterranean anemia.

    Muriana, Piergiorgio / Negri, Giampiero

    The Pan African medical journal

    2018  Volume 31, Page(s) 58

    MeSH term(s) Adult ; Humans ; Male ; Mediastinal Neoplasms/diagnosis ; Mediastinal Neoplasms/pathology ; Myelolipoma/diagnosis ; Myelolipoma/pathology ; Tomography, X-Ray Computed ; beta-Thalassemia/diagnosis ; beta-Thalassemia/pathology
    Language English
    Publishing date 2018-09-27
    Publishing country Uganda
    Document type Case Reports ; Journal Article
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2018.31.58.17041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Tracheobronchial Foreign Body in Small Children: The Combination of Flexible Bronchoscopy and the Urology Stone Retrieval Basket.

    Ciriaco, Paola / Negri, Giampiero

    Archivos de bronconeumologia

    2018  Volume 55, Issue 3, Page(s) 174–175

    MeSH term(s) Bronchi ; Bronchoscopy ; Child, Preschool ; Female ; Foreign Bodies/surgery ; Humans ; Infant ; Trachea ; Urology/instrumentation
    Language Spanish
    Publishing date 2018-08-14
    Document type Letter
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbres.2018.07.010
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  4. Article: Perspective: Did Covid-19 Change Non-small Cell Lung Cancer Surgery Approach?

    Ciriaco, Paola / Carretta, Angelo / Bandiera, Alessandro / Muriana, Piergiorgio / Negri, Giampiero

    Frontiers in surgery

    2021  Volume 8, Page(s) 662592

    Abstract: The novel coronavirus (Covid-19), as of January 2021, infected more than 85 million people worldwide, causing the death of about 1,840 million. Italy had more than 2 million infected and about 75,000 deaths. Many hospitals reduced their ordinary activity ...

    Abstract The novel coronavirus (Covid-19), as of January 2021, infected more than 85 million people worldwide, causing the death of about 1,840 million. Italy had more than 2 million infected and about 75,000 deaths. Many hospitals reduced their ordinary activity by up to 80%, to leave healthcare staff, wards, and intensive care unit (ICU) beds available for the significant number of Covid-19 patients. All this resulted in a prolonged wait for hospitalization of all other patients, including those with non-small cell lung cancer (NSCLC) eligible for surgery. The majority of thoracic surgery departments changed the clinical-therapeutic path of patients, re-adapting procedures based on the needs dictated by the pandemic while not delaying the necessary treatment. The establishment of Covid-19-free hub centers allowed some elective surgery in NSCLC patients but most of the operations were delayed. The technology has partly facilitated patients' visits through telemedicine when security protocols have prevented face-to-face assessments. Multidisciplinary consultations had to deal also with the priority of the NSCLC cases discussed. Interpretation of radiologic exams had to take into account the differential diagnosis with Covid-19 infection. All the knowledge and experience of the past months reveal that the Covid-19 pandemic has not substantially changed the indications and type of surgical treatment in NSCLC. However, the diagnostic process has become more complex, requiring rigorous planning, thus changing the approach with the patients.
    Language English
    Publishing date 2021-05-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2021.662592
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  5. Article: Catamenial Pneumothorax as the First Expression of Thoracic Endometriosis Syndrome and Pelvic Endometriosis.

    Ciriaco, Paola / Muriana, Piergiorgio / Carretta, Angelo / Ottolina, Jessica / Candiani, Massimo / Negri, Giampiero

    Journal of clinical medicine

    2022  Volume 11, Issue 5

    Abstract: Objective: The menstrual-related catamenial pneumothorax (CP) can be the first expression of thoracic endometriosis syndrome (TES), which is the presence of endometriotic lesions in the lungs and pleura, and pelvic endometriosis (PE). This study aims to ...

    Abstract Objective: The menstrual-related catamenial pneumothorax (CP) can be the first expression of thoracic endometriosis syndrome (TES), which is the presence of endometriotic lesions in the lungs and pleura, and pelvic endometriosis (PE). This study aims to analyze our experience with this specific correlation describing our multidisciplinary approach to CP.
    Methods: Hospital records of 32 women, operated for CP at our Department from January 2001 to December 2021 were reviewed. Surgical treatment consisted of videothoracoscopy and laparoscopy when indicated.
    Results: TES and PE were diagnosed in 13 (40.6%) and 12 (37.5%) women, respectively. The association of TES and PE was present in 11 cases (34%). Fifteen patients (46.9%) underwent laparoscopy, of which 11 concurrently with videothoracoscopy. Most of the patients affected had stage III-IV endometriosis (40.6%). All patients received hormonal therapy after surgery. Five patients with PE conceived spontaneously resulting in six live births. The mean follow-up was 117 ± 71 months (range 8-244). Pneumothorax recurrence occurred in six patients (18.8%). At present, all women are asymptomatic, with no sign of pneumothorax recurrence.
    Conclusions: CP might be the first expression of TES and/or PE. A multidisciplinary approach is advocated for optimal management of the disease.
    Language English
    Publishing date 2022-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11051200
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  6. Article ; Online: Laryngo-tracheal stenosis in a woman with ablepharon macrostomia syndrome.

    Ciriaco, Paola / Carretta, Angelo / Negri, Giampiero

    BMC pulmonary medicine

    2019  Volume 19, Issue 1, Page(s) 163

    Abstract: Background: Ablepharon macrostomia syndrome (AMS) is a rare congenital malformation disorder caused by the autosomal-dominant mutations in gene TWIST2. Patients affected by the disease present abnormalities in ectoderm-derived structures mainly ... ...

    Abstract Background: Ablepharon macrostomia syndrome (AMS) is a rare congenital malformation disorder caused by the autosomal-dominant mutations in gene TWIST2. Patients affected by the disease present abnormalities in ectoderm-derived structures mainly consisting in major facial dysmorphic features and rarely in visceral anomalies. The only laryngo-tracheal defect reported is malacia, with no reference to any anatomical stenosis. We describe a unique case of laryngo-tracheal stenosis in a woman, with genetically confirmed AMS currently followed at our Department.
    Case presentation: A 37-year-old Caucasian woman was admitted to the intensive care unit for acute dyspnea that required orotracheal intubation followed by tracheostomy. The bronchoscopy revealed abnormal tracheal tissue at the level of the cricoid and the first three tracheal rings reducing airway caliber by 80% (grade III according to the Cotton-Meyer classification). Treatment of the stenosis by means of temporary tracheostomy and corticosteroids therapy resulted in airway patency restoration and patient's return to her normal activities. Bronchoscopy at four and five months showed disappearance of the abnormal tissue and a residual anatomical laryngo-tracheal stenosis of about 20% (grade I according to the Cotton-Meyer classification) of the normal airway caliber.
    Conclusions: To our knowledge, this is the first patient affected by AMS presenting with laryngo-tracheal stenosis.
    MeSH term(s) Abnormalities, Multiple/diagnosis ; Abnormalities, Multiple/physiopathology ; Adrenal Cortex Hormones/therapeutic use ; Adult ; Dyspnea/etiology ; Eye Abnormalities/diagnosis ; Eye Abnormalities/physiopathology ; Female ; Humans ; Intubation, Intratracheal ; Macrostomia/diagnosis ; Macrostomia/physiopathology ; Mutation ; Trachea/surgery ; Tracheal Stenosis/etiology ; Tracheal Stenosis/therapy ; Tracheostomy
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2019-08-28
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-019-0921-8
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  7. Article ; Online: Treatment of Thoracic Endometriosis Syndrome: A Meta-Analysis and Review.

    Ciriaco, Paola / Muriana, Piergiorgio / Lembo, Rosalba / Carretta, Angelo / Negri, Giampiero

    The Annals of thoracic surgery

    2020  Volume 113, Issue 1, Page(s) 324–336

    Abstract: Background: Thoracic endometriosis syndrome (TES) is a rare disorder characterized by the presence of functional endometrial tissue within the chest cavity. Up to 80% of women with TES present with concomitant pelvic endometriosis. The diagnostic- ... ...

    Abstract Background: Thoracic endometriosis syndrome (TES) is a rare disorder characterized by the presence of functional endometrial tissue within the chest cavity. Up to 80% of women with TES present with concomitant pelvic endometriosis. The diagnostic-curative path is defined by both thoracic surgeons and gynecologists, consistent with the manifestation of the disease. The aim of the study was to analyze the different approaches to generate an ideal diagnosis-treatment algorithm that can be shared by both specialties.
    Methods: We searched PubMed and Scopus for studies that were completed by March 2019 and that included at least 8 patients with TES. Information on preoperative exams, surgical technique, postoperative management, and recurrence of disease was collected for meta-analysis.
    Results: Twenty-five studies including a total of 732 patients were eligible. Almost all of the patients underwent radiologic pelvis investigation (96%; confidence interval [CI], 87%-100%). Videothoracoscopy was the preferred surgical technique (84%; 95% CI, 66%-96%). Intraoperative evaluation revealed the presence of diaphragmatic anomalies in 84% of cases (95% CI, 73%-93%). The overall pooled prevalence of concomitant or staged laparoscopy was 52% (95% CI, 18%-85%). Postoperative hormone therapy was heterogeneous with a pooled prevalence of 61% (95% CI, 33%-86%; I
    Conclusions: TES should be managed jointly by thoracic surgeons and gynecologists. Chest-abdomen magnetic resonance imaging seems to offer the most details for TES. Combined or staged videothoracoscopy and laparoscopy can provide adequate information to fine-tune proper surgical treatment and postoperative medical therapy.
    MeSH term(s) Algorithms ; Endometriosis/diagnosis ; Endometriosis/surgery ; Female ; Humans ; Syndrome ; Thorax
    Language English
    Publishing date 2020-12-18
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2020.09.064
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    Zs.A 252: Show issues Location:
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  8. Article ; Online: Surgical treatment of single and multiple thymoma recurrences.

    Carretta, Angelo / Ciriaco, Paola / Muriana, Piergiorgio / Bandiera, Alessandro / Negri, Giampiero

    General thoracic and cardiovascular surgery

    2019  Volume 68, Issue 4, Page(s) 350–356

    Abstract: Objectives: A significant number of patients with thymoma develop a recurrence after surgery. The results of previous studies analyzing therapeutic strategies in the treatment of recurrences have been controversial. Aim of the study was to evaluate the ... ...

    Abstract Objectives: A significant number of patients with thymoma develop a recurrence after surgery. The results of previous studies analyzing therapeutic strategies in the treatment of recurrences have been controversial. Aim of the study was to evaluate the role of surgery in the treatment of thymoma recurrences assessing prognostic factors related with survival.
    Methods: Between January 1993 and September 2018, 27 of 161 patients had a recurrence after complete thymoma resection. Twenty-one (13%) underwent surgical treatment of the recurrence. Primary tumor stage was: I in a patient, IIa in five, IIb in nine and III in six. The recurrence was regional in all patients and both regional and distant in four. WHO histological classification was: A in two patients, B1 in two, B2 in seven and B3 in 10 patients.
    Results: Median disease-free survival from surgical treatment of the primary tumor and recurrence was 44 months (1-124). Thirty-eight operations were performed (range 1-5). Complete resection rate was 66%. Adjuvant radiotherapy and chemotherapy after surgical treatment of recurrences were performed respectively in ten and nine patients, including eight patients with multiple recurrences. Five and 10-year tumor-specific survival from recurrence was, respectively, 79% and 66%. Survival analysis showed a significant correlation between survival and WHO classification, with a significantly lower survival in patients with B3 tumors in comparison with A to B2 tumors (p = 0.026).
    Conclusions: Long-term survival was observed following surgical treatment of thymoma recurrences. These results were observed even after multiple recurrences when surgical treatment was performed within a multimodality oncological approach.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Disease-Free Survival ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Recurrence, Local/surgery ; Prognosis ; Radiotherapy, Adjuvant ; Retrospective Studies ; Survival Analysis ; Thymoma/surgery ; Thymus Neoplasms/surgery ; Treatment Outcome
    Language English
    Publishing date 2019-10-22
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2376888-5
    ISSN 1863-6713 ; 1863-6705
    ISSN (online) 1863-6713
    ISSN 1863-6705
    DOI 10.1007/s11748-019-01229-w
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  9. Article: Therapeutic strategy for tracheal chondrosarcoma: report of two cases.

    Carretta, Angelo / Ciriaco, Paola / Bandiera, Alessandro / Muriana, Piergiorgio / Arrigoni, Gianluigi / Negri, Giampiero

    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

    2020  Volume 90, Issue 1

    Abstract: Primary chondrosarcoma of the trachea is an extremely rare tumor. We report two cases of tracheal chondrosarcoma describing the role of surgical and conservative treatment. Endoscopic treatment with rigid bronchoscopy was performed in both patients to ... ...

    Abstract Primary chondrosarcoma of the trachea is an extremely rare tumor. We report two cases of tracheal chondrosarcoma describing the role of surgical and conservative treatment. Endoscopic treatment with rigid bronchoscopy was performed in both patients to restore airway patency and obtain histological specimens for diagnosis. One of the patients subsequently underwent successful tracheal resection and reconstruction. The other patient, who had a contraindication to surgical treatment due to associated diseases underwent iterative endoscopic LASER treatment and is alive three years after the first diagnosis. Surgical treatment remains the treatment of choice of tracheal chondrosarcoma. When surgery is contraindicated endoscopic treatment may allow relatively longterm survival due to the slow growth of these tumors.
    MeSH term(s) Bronchoscopy ; Chondrosarcoma/diagnosis ; Chondrosarcoma/therapy ; Endoscopy ; Humans ; Laser Therapy ; Reconstructive Surgical Procedures ; Tracheal Neoplasms/diagnosis ; Tracheal Neoplasms/therapy
    Language English
    Publishing date 2020-03-12
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 1160940-0
    ISSN 1122-0643 ; 1120-0391
    ISSN 1122-0643 ; 1120-0391
    DOI 10.4081/monaldi.2020.1223
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  10. Article: Pulmonary nodules and mini-invasive lung resection: do we have the right "tool" for their intraoperative localization?

    Ciriaco, Paola / Muriana, Piergiorgio / Negri, Giampiero

    Journal of thoracic disease

    2017  Volume 9, Issue 11, Page(s) 4216–4218

    Language English
    Publishing date 2017-12-18
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2017.10.87
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