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  1. Article ; Online: Urolithiasis – Therapie und Rezidivprävention unter Berücksichtigung geschlechtsspezifischer Aspekte.

    Siener, Roswitha / Strohmaier, Walter L / Neisius, Andreas

    Urologie (Heidelberg, Germany)

    2022  Volume 61, Issue 10, Page(s) 1076–1082

    Abstract: The prevalence of urolithiasis is steadily increasing worldwide in both genders. Diet and lifestyle, such as the rising prevalence of obesity and other metabolic syndrome traits, are considered key factors in this trend. Gender differences as a result of ...

    Title translation Urolithiasis-Therapy and recurrence prevention taking into account gender-specific aspects.
    Abstract The prevalence of urolithiasis is steadily increasing worldwide in both genders. Diet and lifestyle, such as the rising prevalence of obesity and other metabolic syndrome traits, are considered key factors in this trend. Gender differences as a result of interventional therapy for urolithiasis have not been observed. However, iatrogenic injury to the male urethra is considered the most common reason for urethral strictures after endourologic (stone) therapy. In contrast, sepsis, as the major cause of urinary stone-related mortality, is more frequently reported in women after ureterorenoscopy and percutaneous nephrolithotomy. There are also differences in the frequency of various types of stones between men and women. Calcium oxalate and uric acid stones are more commonly observed in men, while carbonate apatite and struvite are diagnosed more often in women. Urinary stone analysis is therefore paramount for successful recurrence prevention. Diagnosis is based on the assignment of patients to the low-risk or high-risk group. The medical nutrition and pharmacological measures for the therapy of the respective type of stone are based on the risk factors in 24 h urine samples. A personalized approach that accounts for gender differences could further improve treatment, and recurrence prevention decisions for urinary stones.
    MeSH term(s) Calcium Oxalate/analysis ; Female ; Humans ; Male ; Struvite ; Uric Acid/analysis ; Urinary Calculi/epidemiology ; Urolithiasis/diagnosis
    Chemical Substances Calcium Oxalate (2612HC57YE) ; Uric Acid (268B43MJ25) ; Struvite (AW3EJL1462)
    Language German
    Publishing date 2022-08-26
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2731-7072
    ISSN (online) 2731-7072
    DOI 10.1007/s00120-022-01912-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ureterkolik--Medikamentöse Expulsionstherapie.

    Neisius, Andreas

    Aktuelle Urologie

    2015  Volume 46, Issue 6, Page(s) 433–434

    Language German
    Publishing date 2015-11
    Publishing country Germany
    Document type Comment ; Journal Article
    ZDB-ID 124847-9
    ISSN 1438-8820 ; 0001-7868
    ISSN (online) 1438-8820
    ISSN 0001-7868
    DOI 10.1055/s-0035-1569087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prospective Analysis of Versatility and User Satisfaction with a Novel Single-Use Cystoscope with Working Channel.

    Lütfrenk, Thomas / Neisius, Andreas / Rausch, Steffen / Salem, Johannes / Kuru, Timur H

    Urologia internationalis

    2023  Volume 107, Issue 6, Page(s) 570–577

    Abstract: Introduction: In the present study, a prospective systematic assessment of the clinical utility of the Ambu® aScopeTM 4 Cysto Reverse Deflection with regard to image quality, maneuverability, and navigation in an outpatient and inpatient setting was ... ...

    Abstract Introduction: In the present study, a prospective systematic assessment of the clinical utility of the Ambu® aScopeTM 4 Cysto Reverse Deflection with regard to image quality, maneuverability, and navigation in an outpatient and inpatient setting was performed.
    Materials and methods: A prospective multicenter study was performed for evaluation of the instrument during routine cystoscopy. We evaluated the clinical performance of the instruments using a standardized user questionnaire in different categories including image quality, treatment success, imaging of all areas of the urinary bladder, quality of navigation, flexibility of the endoscope, and satisfaction with the device. Statistical analyses were performed by SPSS using the Kruskal-Wallis and Wilcoxon-Mann-Whitney tests. A p value of p ≤ 0.05 was defined as statistically significant.
    Results: A total of 200 cystoscopies were performed, and the questionnaire response rate was 100%. The image quality was rated as very good in 65.5% (n = 131), good in 30.5% (n = 61), and neutral in 4% (n = 8) of cases. The criteria for poor or very poor were not mentioned. The characteristic "treatment success based on image quality" was also evaluated as very good in 49% (n = 98) and good in 50.5% (n = 101). The analysis revealed a very good or good overall impression of the examiners in all cases. Replacement of the cystoscope was not necessary during any of the examinations. However, in 3 cases, technical difficulties were documented. Further analysis of the data showed that physicians with less professional experience rated the visualization of the urinary bladder (p = 0.007) and the treatment success with regard to image quality significantly worse (p = 0.007).
    Conclusion: The Ambu® aScope™ 4 Cysto Reverse Deflection shows high satisfaction values among users in clinical routine. In analogy to other studies with flexible endoscopes, urologists with more professional experience show higher satisfaction values than examiners with less training in flexible endoscopy.
    MeSH term(s) Humans ; Equipment Design ; Cystoscopes ; Cystoscopy/methods ; Urinary Bladder/diagnostic imaging
    Language English
    Publishing date 2023-04-18
    Publishing country Switzerland
    Document type Multicenter Study ; Journal Article
    ZDB-ID 204045-1
    ISSN 1423-0399 ; 0042-1138
    ISSN (online) 1423-0399
    ISSN 0042-1138
    DOI 10.1159/000529488
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Positionspapier des Arbeitskreises „Urologische Akutmedizin“.

    Anheuser, Petra / Michels, Guido / Gakis, Georgios / Neisius, Andreas / Steffens, Joachim / Kranz, Jennifer

    Urologie (Heidelberg, Germany)

    2023  Volume 62, Issue 9, Page(s) 936–940

    Abstract: Emergency patients with acute genitourinary system diseases are frequently encountered in both outpatient and clinical emergency structures. It is estimated that one-third of all inpatients in a urology clinic initially present as an emergency. In ... ...

    Title translation Position paper of the working group Urological Acute Medicine.
    Abstract Emergency patients with acute genitourinary system diseases are frequently encountered in both outpatient and clinical emergency structures. It is estimated that one-third of all inpatients in a urology clinic initially present as an emergency. In addition to general emergency medicine knowledge, specialized urologic expertise is a prerequisite for the care of these patients, which is needed early and specifically for optimal treatment outcomes. It must be taken into account that, on the one hand, the current structures of emergency care still lead to delays in patient care despite positive developments in recent years. On the other hand, most hospital emergency facilities need urologic expertise on site. In addition, politically intended changes in our health care system, which drive an increasing ambulantization of medicine and condition a further centralization of emergency clinics, become effective. The aim of the newly established working group "Urological Acute Medicine" is to ensure and further improve the quality of care for emergency patients with acute genitourinary system diseases and, in consensus with the German Society of Interdisciplinary Emergency and Acute Medicine, to define precise task distributions and interfaces of both specialities.
    MeSH term(s) Humans ; Urology ; Delivery of Health Care ; Emergency Medicine ; Urogenital Diseases ; Hospitals
    Language German
    Publishing date 2023-04-28
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7072
    ISSN (online) 2731-7072
    DOI 10.1007/s00120-023-02090-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ureteral Stones: Shockwave Lithotripsy or Ureteroscopy, Which is Best?

    Türk, Christian / Petřík, Aleš / Neisius, Andreas

    European urology

    2021  Volume 80, Issue 1, Page(s) 55–56

    MeSH term(s) Humans ; Lithotripsy/adverse effects ; Ureteral Calculi/therapy ; Ureteroscopy
    Language English
    Publishing date 2021-04-08
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2021.03.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: MR-Guided Transurethral Ultrasound Ablation of Prostate Cancer: Initial Experience of Monitoring Tumor Response by Dynamic Apparent Diffusion Coefficient Measurements at 3.0 T.

    Meyer, Lena / Bohlscheid, Andreas / Lemmer, Oscar / van de Plas, Jeroen / Leboutte, Francois / Hadaschik, Boris A / Neisius, Andreas / Willinek, Winfried A

    Urologia internationalis

    2023  Volume 107, Issue 7, Page(s) 684–692

    Abstract: Introduction: Diffusion-weighted imaging (DWI) as part of multiparametric magnetic resonance imaging (mpMRI) is an important sequence for the detection of prostate cancer (PCa). The objective of this retrospective analysis was to evaluate changes in ... ...

    Abstract Introduction: Diffusion-weighted imaging (DWI) as part of multiparametric magnetic resonance imaging (mpMRI) is an important sequence for the detection of prostate cancer (PCa). The objective of this retrospective analysis was to evaluate changes in apparent diffusion coefficient (ADC) measurements in biopsy-proven PCa undergoing TULSA-PRO (MR-guided transurethral ultrasound ablation of the prostate) at 3.0 T after 1, 3, and 6-12 months posttreatment.
    Methods: Nineteen patients underwent follow-up examinations after 1, 3, and 6-12 months including mpMRI at 3.0 T and urological-clinical examinations with quantitative analysis of ADCs.
    Results: In PCa, a significant increase of ADC values after 6-12 months was measured after TULSA-PRO treatment by 29.1% (pre-TULSA: 0.79 ± 0.16 × 10-3 mm2/s, 6-12 months: 1.02 ± 0.35 × 10-3 mm2/s), while the corresponding value in the reference tissue decreased by 48.5% (pre-TULSA: 1.20 ± 0.15 × 10-3 mm2/s, 6-12 months: 0.91 ± 0.29 × 10-3 mm2/s). The mean ADC values in the early follow-up groups at 1 and 3 months did not change significantly.
    Conclusion: DWI with ADC as part of mpMRI can serve as a biomarker to dynamically monitor the follow-up after TULSA after 6-12 months. For early posttreatment progression, it is not suitable due to too many confounding variables.
    MeSH term(s) Male ; Humans ; Retrospective Studies ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/surgery ; Diffusion Magnetic Resonance Imaging/methods ; Prostate/diagnostic imaging ; Prostate/surgery ; Prostate/pathology ; Biopsy
    Language English
    Publishing date 2023-04-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 204045-1
    ISSN 1423-0399 ; 0042-1138
    ISSN (online) 1423-0399
    ISSN 0042-1138
    DOI 10.1159/000529873
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Follow-up of urolithiasis patients after treatment: an algorithm from the EAU Urolithiasis Panel.

    Lombardo, Riccardo / Tzelves, Lazaros / Geraghty, Robert / Davis, Niall F / Neisius, Andreas / Petřík, Ales / Gambaro, Giovanni / Türk, Christian / Somani, Bhaskar / Thomas, Kay / Skolarikos, Andreas

    World journal of urology

    2024  Volume 42, Issue 1, Page(s) 202

    Abstract: Objective: To develop a follow-up algorithm for urinary stone patients after definitive treatment.: Materials and methods: The panel performed a systematic review on follow-up of urinary stone patients after treatment (PROSPERO: CRD42020205739). ... ...

    Abstract Objective: To develop a follow-up algorithm for urinary stone patients after definitive treatment.
    Materials and methods: The panel performed a systematic review on follow-up of urinary stone patients after treatment (PROSPERO: CRD42020205739). Given the lack of comparative studies we critically evaluated the literature and reached a consensus on the follow-up scheme.
    Results: A total of 76 studies were included in the analysis, including 17 RCTs. In the stone-free general population group, 71-100% of patients are stone-free at 12 months while 29-94% remain stone-free at 36 months. We propose counselling these patients on imaging versus discharge after the first year. The stone-free rate in high-risk patients not receiving targeted medical therapy is < 40% at 36 months, a fact that supports imaging, metabolic, and treatment monitoring follow-up once a year. Patients with residual fragments ≤ 4 mm have a spontaneous expulsion rate of 18-47% and a growth rate of 10-41% at 12 months, supporting annual imaging follow-up. Patients with residual fragments > 4 mm should be considered for surgical re-intervention based on the low spontaneous expulsion rate (13% at 1 year) and high risk of recurrence. Plain film KUB and/or kidney ultrasonography based on clinicians' preference and stone characteristics is the preferred imaging follow-up. Computed tomography should be considered if patient is symptomatic or intervention is planned.
    Conclusions: Based on evidence from the systematic review we propose, for the first time, a follow-up algorithm for patients after surgical stone treatment balancing the risks of stone recurrence against the burden of radiation from imaging studies.
    MeSH term(s) Humans ; Follow-Up Studies ; Urolithiasis/diagnosis ; Urolithiasis/surgery ; Urinary Calculi/therapy ; Tomography, X-Ray Computed/methods ; Algorithms ; Kidney Calculi/therapy
    Language English
    Publishing date 2024-03-28
    Publishing country Germany
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-024-04872-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Future perspectives of flexible ureteroscopy.

    Secker, Armin / Rassweiler, Jens / Neisius, Andreas

    Current opinion in urology

    2019  Volume 29, Issue 2, Page(s) 113–117

    Abstract: Purpose of review: In the recent past, there were numerous and promising technological developments in the field of endourology leading to tremendous changes in the management of urolithiasis. This review will try to weave ancient stone therapy with the ...

    Abstract Purpose of review: In the recent past, there were numerous and promising technological developments in the field of endourology leading to tremendous changes in the management of urolithiasis. This review will try to weave ancient stone therapy with the very modern advent of flexible ureteroscopy and recent developments in robotic systems.
    Recent findings: In the broad field of flexible ureteroscopy for stone surgery, new disposable scopes have been developed and established. The use of robotic instruments is also a new and interesting concept. Additionally, clinical research on the understanding of laser features leads to a specific and appropriate use of lasers for lithotripsy, both holmium, and nowadays also interestingly thulium.
    Summary: Disposable, digital flexible ureteroscopes for the treatment of both ureteric and kidney stones are taking an essential role in the medical field. Until recently, the clinically relevant laser systems for stone surgery during ureteroscopy are mainly based on Holmium laser YAG (Ho:YAG) devices, but a new thulium variant with promising features is giving interesting results. Additional research in laser features will guide to a better, more effective and safer treatment algorithm. Robotic technologies are promising but their definitive role still needs to be determined.
    MeSH term(s) Humans ; Kidney Calculi/diagnosis ; Kidney Calculi/therapy ; Lithotripsy ; Lithotripsy, Laser ; Treatment Outcome ; Ureteroscopes ; Ureteroscopy/instrumentation ; Ureteroscopy/methods ; Urolithiasis/diagnosis ; Urolithiasis/therapy
    Language English
    Publishing date 2019-02-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1091792-5
    ISSN 1473-6586 ; 0963-0643
    ISSN (online) 1473-6586
    ISSN 0963-0643
    DOI 10.1097/MOU.0000000000000575
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Conference proceedings: Ist eine Urodynamik in der Diagnostik vor Botoxtherapie bei iOAB nötig und sinnvoll?

    Nestler, Sebastian / Grüne, Britta / Neisius, Andreas

    2021  , Page(s) 15

    Event/congress 32. Kongress der Deutschen Kontinenz Gesellschaft; sine loco [digital]; Deutsche Kontinenz Gesellschaft e.V.; 2021
    Keywords Medizin, Gesundheit
    Publishing date 2021-11-04
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/21dkg15
    Database German Medical Science

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  10. Conference proceedings: Auf dem Weg zur rückstandsfreien Steinsanierung nach ureteroskopischer Laserlithotripsie – die Hydrogelmethode

    Amiel, Thomas / Straub, Michael / Neisius, Andreas / Netsch, Christopher / Secker, Armin / Fisang, Christian / Grunwald, Ingo

    2023  , Page(s) 23oegu41

    Event/congress 49. Tagung der Österreichischen Gesellschaft für Urologie und Andrologie und der Bayerischen Urologenvereinigung; Linz, Österreich; ; Bayerische Urologenvereinigung; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-05-02
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23oegu41
    Database German Medical Science

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