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  1. Book ; Online ; E-Book: Neurointensive Care Unit

    Nelson, Sarah E. / Nyquist, Paul A.

    Clinical Practice and Organization

    (Current Clinical Neurology,)

    2020  

    Abstract: This book offers valuable guidance to neurointensivists, other neurocritical care staff, and those desiring to develop a neurocritical care unit via a thorough discussion of neurological emergencies and neurocritical care unit organization. This ... ...

    Author's details edited by Sarah E. Nelson, Paul A. Nyquist
    Series title Current Clinical Neurology,
    Abstract This book offers valuable guidance to neurointensivists, other neurocritical care staff, and those desiring to develop a neurocritical care unit via a thorough discussion of neurological emergencies and neurocritical care unit organization. This comprehensive volume begins with a review of acute neurological emergencies as managed clinically in the neurocritical care unit. Topics include acute cerebrovascular, neurological, and neurosurgical disorders. The unique aspect of this book is its description of the organization of the neurocritical care unit. We focus on how other services in the hospital interact with and assist neurocritical care operations, telemedicine/telestroke, and neurocritical care personnel and their roles. A review of expected outcomes of neurocritical care conditions is also included. Neurointensivists, neurocritical care unit staff leadership, hospital administrators, and those interested in developing a neurocritical care unit will find Neurointensive Care Unit: Clinical Practice and Organization to be an invaluable guide.
    Keywords Neurology  ; Critical care medicine ; Practice of medicine ; Neurology ; Intensive / Critical Care Medicine ; Practice and Hospital Management
    Subject code 616.80428
    Language English
    Size 1 online resource (XV, 396 p. 75 illus., 39 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Humana
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Note Includes index.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-36548-4 ; 3-030-36547-6 ; 978-3-030-36548-6 ; 978-3-030-36547-9
    DOI 10.1007/978-3-030-36548-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Reversible Cerebral Vasoconstriction Syndrome and Female Sex: A Narrative Review.

    Nelson, Sarah E

    Stroke

    2024  Volume 55, Issue 4, Page(s) 1113–1117

    Abstract: Reversible cerebral vasoconstriction syndrome (RCVS) refers to segmental, multifocal constriction of intracranial arteries along with acute headache and resolves within weeks. It occurs more commonly in women, and 1 well-known manifestation of RCVS is ... ...

    Abstract Reversible cerebral vasoconstriction syndrome (RCVS) refers to segmental, multifocal constriction of intracranial arteries along with acute headache and resolves within weeks. It occurs more commonly in women, and 1 well-known manifestation of RCVS is postpartum angiopathy. Furthermore, the female sex is included in scoring systems designed to assist with diagnosing RCVS. Nonetheless, the literature is mixed regarding the true role of female and pregnancy-related factors in the pathophysiology of RCVS, and it is similarly unclear whether management of this disorder differs by sex. Given the association of RCVS with female sex and the importance of highlighting, recognizing, and managing stroke etiologies in women, herein, the author reviews what is currently known and unknown about the topic of RCVS in women.
    MeSH term(s) Pregnancy ; Humans ; Female ; Vasoconstriction/physiology ; Vasospasm, Intracranial/etiology ; Stroke/diagnosis ; Headache/etiology ; Headache Disorders, Primary/etiology ; Headache Disorders, Primary/complications
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.123.046312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lecanemab for Alzheimer Disease: Is It Worth It?

    Nelson, Sarah E / Lopez, Oscar L

    Neurology

    2024  Volume 102, Issue 7, Page(s) e209265

    MeSH term(s) Humans ; Alzheimer Disease ; Antibodies, Monoclonal, Humanized
    Chemical Substances lecanemab (12PYH0FTU9) ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Editorial
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000209265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Special issue: Mercury and nitrogen biogeochemistry in paired watershed studies in Acadia National Park, Maine, USA

    Nelson, Sarah J.

    (Environmental monitoring and assessment ; 126,1/3)

    2007  

    Title variant Mercury and nitrogen biogeochemistry in paired watershed studies in Acadia National Park, Maine, USA
    Author's details guest ed.: Sarah J. Nelson
    Series title Environmental monitoring and assessment ; 126,1/3
    Collection
    Language English
    Size 143 S. : Ill., graph. Darst., Kt.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT015022533
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  5. Article ; Online: Topical Review: Getting into the head of youth with chronic pain: how theory of mind deficits may relate to the development and maintenance of pediatric pain.

    Nestor, Bridget A / Kossowsky, Joe / Nelson, Sarah M

    Journal of pediatric psychology

    2024  Volume 49, Issue 3, Page(s) 224–230

    Abstract: Objective: Theory of mind (ToM) is the ability to understand the thoughts, feelings, and mental states of others and is critical for effective social and psychological functioning. ToM deficits have been associated with various psychological disorders ... ...

    Abstract Objective: Theory of mind (ToM) is the ability to understand the thoughts, feelings, and mental states of others and is critical for effective social and psychological functioning. ToM deficits have been associated with various psychological disorders and identified in adult pain populations. For youth with chronic pain, ToM deficits may underlie the biological, psychological, and social factors that contribute to their experience of pain, but this remains poorly understood.
    Methods: This topical review explored the extant literature in the areas of ToM and chronic pain, particularly for pediatric populations, with respect to biological, psychological, and social elements of the biopsychosocial model of pain.
    Results: ToM deficits may be present alongside previously identified biological, psychological, and social correlates of pediatric pain, as a vulnerability, mechanism, and/or consequence. Biologically, ToM deficits may relate to cortisol abnormalities and neurobiological substrates of pain processing. Psychologically, ToM deficits may stem from pain-focused cognitions, thus impacting relationships and fueling impairment. Socially, chronic pain may preclude normative development of ToM abilities through social withdrawal, thereby exacerbating the experience of pain.
    Conclusion: Taken together, ToM deficits may be associated with increased risk for the development and/or maintenance of pediatric chronic pain, and pediatric chronic pain may similarly confer risk for ToM deficits. Future research should investigate the nature of ToM abilities in youth with chronic pain to test these hypotheses and ultimately inform ToM-focused and pain-based interventions, as this ability has been demonstrated to be modifiable.
    MeSH term(s) Adult ; Humans ; Adolescent ; Child ; Theory of Mind ; Chronic Pain ; Emotions ; Cognition ; Cognition Disorders/psychology ; Neuropsychological Tests
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 625329-5
    ISSN 1465-735X ; 0146-8693
    ISSN (online) 1465-735X
    ISSN 0146-8693
    DOI 10.1093/jpepsy/jsae009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: COVID-19 and ethics in the ICU.

    Nelson, Sarah E

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 519

    MeSH term(s) COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Ethics, Medical ; Humans ; Intensive Care Units/ethics ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; United States/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-08-25
    Publishing country England
    Document type Editorial
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03250-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Commentary on Associations of Radiographic Small Vessel Disease with Acute Intracerebral Hemorrhage Volume, Hematoma Expansion, and Intraventricular Hemorrhage.

    Nelson, Sarah E

    Neurocritical care

    2019  Volume 32, Issue 2, Page(s) 361–362

    MeSH term(s) Cerebral Hemorrhage ; Cerebral Small Vessel Diseases ; Hematoma ; Humans
    Language English
    Publishing date 2019-11-22
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2381896-7
    ISSN 1556-0961 ; 1541-6933
    ISSN (online) 1556-0961
    ISSN 1541-6933
    DOI 10.1007/s12028-019-00884-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Valsalva Maneuver to Identify Dermal Bleeders after Paramedian Flap Elevation Under Local Anesthesia.

    Brown, Alistair Campbell / Nelson, Toby / Nelson, Sarah C

    Journal of cutaneous and aesthetic surgery

    2023  Volume 16, Issue 3, Page(s) 237–238

    Abstract: The paramedian forehead flap (PFF) provides a reliable reconstruction option for complex nasal tip defects. The robust blood supply from a well perfused pedicle allows for reconstruction of large defects of the nasal tip for which simpler methods/ ... ...

    Abstract The paramedian forehead flap (PFF) provides a reliable reconstruction option for complex nasal tip defects. The robust blood supply from a well perfused pedicle allows for reconstruction of large defects of the nasal tip for which simpler methods/techniques would provide inadequate coverage or result in inferior cosmesis. A well-designed PFF containing the supratrochlear artery inherently predisposes to small vessel bleeding from the pedicles cut edge. Due to the well perfused nature of the pedicle, there is an increased risk of post-operative bleeding. We describe a technique for better identifying bleeding points from the pedicle to optimise intra-operative haemostasis by performing the Valsalva maneuver using a syringe intraoperatively.
    Language English
    Publishing date 2023-12-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 2461107-4
    ISSN 0974-5157 ; 0974-2077
    ISSN (online) 0974-5157
    ISSN 0974-2077
    DOI 10.4103/JCAS.JCAS_98_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: 2D optical confinement in an etchless stratified trench waveguide.

    Reddy, Jay W / Nelson, Sarah / Chamanzar, Maysamreza

    Optics express

    2023  Volume 31, Issue 4, Page(s) 5140–5154

    Abstract: We demonstrate novel trapezoidal and rectangular stratified trench optical waveguide designs that feature low-loss two-dimensional confinement of guided optical modes that can be realized in continuous polymer thin film layers formed in a trench mold. ... ...

    Abstract We demonstrate novel trapezoidal and rectangular stratified trench optical waveguide designs that feature low-loss two-dimensional confinement of guided optical modes that can be realized in continuous polymer thin film layers formed in a trench mold. The design is based on geometrical bends in a thin film core to enable two-dimensional confinement of light in the transverse plane, without any variation in the core thickness. Incidentally, the waveguide design would completely obviate the need for etching the waveguide core, avoiding the scattering loss due to the etched sidewall roughness. This new design exhibits an intrinsic leakage loss due to coupling of light out of the trench, which can be minimized by choosing an appropriate waveguide geometry. Finite-difference eigenmode simulation demonstrates a low intrinsic leakage loss of less than 0.15 dB/cm. We discuss the principle of operation of these stratified trench waveguides and present the design and numerical simulations of a specific realization of this waveguide geometry. The design considerations and tradeoffs in propagation loss and confinement compared with traditional ridge waveguides are discussed.
    Language English
    Publishing date 2023-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.466004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cloud-based biomedical data storage and analysis for genomic research: Landscape analysis of data governance in emerging NIH-supported platforms.

    Dahlquist, Jacklyn M / Nelson, Sarah C / Fullerton, Stephanie M

    HGG advances

    2023  Volume 4, Issue 3, Page(s) 100196

    Abstract: The storage, sharing, and analysis of genomic data poses technical and logistical challenges that have precipitated the development of cloud-based computing platforms designed to facilitate collaboration and maximize the scientific utility of data. To ... ...

    Abstract The storage, sharing, and analysis of genomic data poses technical and logistical challenges that have precipitated the development of cloud-based computing platforms designed to facilitate collaboration and maximize the scientific utility of data. To understand cloud platforms' policies and procedures and the implications for different stakeholder groups, in summer 2021, we reviewed publicly available documents (N = 94) sourced from platform websites, scientific literature, and lay media for five NIH-funded cloud platforms (the All of Us Research Hub, NHGRI AnVIL, NHLBI BioData Catalyst, NCI Genomic Data Commons, and the Kids First Data Resource Center) and a pre-existing data sharing mechanism, dbGaP. Platform policies were compared across seven categories of data governance: data submission, data ingestion, user authentication and authorization, data security, data access, auditing, and sanctions. Our analysis finds similarities across the platforms, including reliance on a formal data ingestion process, multiple tiers of data access with varying user authentication and/or authorization requirements, platform and user data security measures, and auditing for inappropriate data use. Platforms differ in how data tiers are organized, as well as the specifics of user authentication and authorization across access tiers. Our analysis maps elements of data governance across emerging NIH-funded cloud platforms and as such provides a key resource for stakeholders seeking to understand and utilize data access and analysis options across platforms and to surface aspects of governance that may require harmonization to achieve the desired interoperability.
    MeSH term(s) Humans ; Cloud Computing ; Population Health ; Genomics/methods ; Genome ; Information Storage and Retrieval
    Language English
    Publishing date 2023-04-12
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2666-2477
    ISSN (online) 2666-2477
    DOI 10.1016/j.xhgg.2023.100196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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