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  1. Book ; Thesis: Der Einfluss von Tumorerkrankung und Hochrisikotherapie auf das Körpergrößenwachstum von Neuroblastompatienten

    Berkenhoff, Mischa Alexander / Simon, Thorsten / Neuschmelting, Volker

    2022  

    Author's details vorgelegt von Mischa Alexander Berkenhoff ; 1. Gutachter: Professor Dr. med. T. Simon, 2. Gutachter: Privatdozent Dr. med. V. Neuschmelting ; aus dem Zentrum für Kinder- und Jugendmedizin der Universität zu Köln, Klinik und Poliklinik für Kinder- und Jugendmedizin
    Subject code 610
    Language German
    Size 91 Seiten, Diagramme
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität zu Köln, 2021
    HBZ-ID HT021303488
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 D 185 order for loan Magazin

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  2. Book ; Thesis: Future directions of imaging-guidance in neurooncological surgery

    Neuschmelting, Volker

    = Neue Entwicklungen in der Bildgebungsgestützten Neuroonkologischen Chirurgie

    2018  

    Title variant Neue Entwicklungen in der Bildgebungsgestützten Neuroonkologischen Chirurgie
    Institution Universitätsklinikum Köln / Klinik für Allgemeine Neurochirurgie
    Author's details vorgelegt von Dr. med. Volker Neuschmelting ; aus dem Zentrum für Neurochirurgie der Universität zu Köln, Klinik für Allgemeine Neurochirurgie
    Subject code 610
    Language English
    Size 1 Band verschiedene Seitenzählungen, Illustrationen, Diagramme
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Habilitationsschrift, Universität zu Köln, 2019
    Note Zusammenfassung in deutscher und englischer Sprache
    HBZ-ID HT020022460
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2019 E 337 order for loan Magazin

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  3. Book ; Thesis: Die diagnostische Facettengelenksinfiltration vor monosegmentaler lumbaler Fusionsoperation zur Prädiktion des Operationserfolgs im kurz- bis mittelfristigen Verlauf

    Karches, Leila / Siewe, Jan Norbert / Neuschmelting, Volker

    eine monozentrische, prospektive Beobachtungsstudie

    2021  

    Institution Universitätsklinikum Köln / Klinik und Poliklinik für Orthopädie und Unfallchirurgie
    Author's details vorgelegt von Leila Karches ; 1. Gutachter: Privatdozent Dr. med. J. Siewe, 2. Gutachter: Privatdozent Dr. med. V. Neuschmelting ; aus der Klinik und Poliklinik für Orthopädie und Unfallchirurgie der Universität zu Köln
    Subject code 610
    Language German
    Size 117 Seiten, Illustrationen, Diagramme
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität zu Köln, 2021
    HBZ-ID HT021602719
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 D 546 order for loan Magazin

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  4. Book ; Online ; Thesis: Die diagnostische Facettengelenksinfiltration vor monosegmentaler lumbaler Fusionsoperation zur Prädiktion des Operationserfolgs im kurz- bis mittelfristigen Verlauf

    Karches, Leila / Siewe, Jan Norbert / Neuschmelting, Volker

    eine monozentrische, prospektive Beobachtungsstudie

    2021  

    Institution Universitätsklinikum Köln / Klinik und Poliklinik für Orthopädie und Unfallchirurgie
    Author's details vorgelegt von Leila Karches ; 1. Gutachter: Privatdozent Dr. med. J. Siewe, 2. Gutachter: Privatdozent Dr. med. V. Neuschmelting ; aus der Klinik und Poliklinik für Orthopädie und Unfallchirurgie der Universität zu Köln
    Subject code 610
    Language German
    Size 1 Online-Ressource (117 Seiten), Illustrationen
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität zu Köln, 2021
    Note Open Access
    HBZ-ID HT021268808
    DOI 10.4126/FRL01-006431919
    Database Repository for Life Sciences

    Full text online

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  5. Article ; Online: Personalisierte Hirntumorchirurgie mittels intraoperativer stimulierter Raman-Histologie.

    Meißner, Anna-Katharina / Goldbrunner, Roland / Neuschmelting, Volker

    Chirurgie (Heidelberg, Germany)

    2024  Volume 95, Issue 4, Page(s) 274–279

    Abstract: Background: In brain tumor surgery a personalized surgical approach is crucial to achieve a maximum safe tumor resection. The extent of resection decisively depends on the histological diagnosis. Stimulated Raman histology (SRH), a fiber laser-based ... ...

    Title translation Intraoperative stimulated Raman histology for personalized brain tumor surgery.
    Abstract Background: In brain tumor surgery a personalized surgical approach is crucial to achieve a maximum safe tumor resection. The extent of resection decisively depends on the histological diagnosis. Stimulated Raman histology (SRH), a fiber laser-based optical imaging method, offers the possibility for evaluation of an intraoperative diagnosis in a few minutes.
    Objective: To provide an overview on the applications of SRH in neurosurgery and transference of the technique to other surgical disciplines.
    Methods: Description of the technique and review of the current literature on SRH.
    Results: The SRH technique was successfully used in multiple neuro-oncological tumor entities. Initial pilot projects showed the potential for analysis of extracranial tumors.
    Conclusion: The use of SRH provides a near real-time diagnosis with high diagnostic accuracy and provides further developmental potential to improve personalized tumor surgery.
    MeSH term(s) Humans ; Neurosurgical Procedures/methods ; Optical Imaging ; Neurosurgery ; Histological Techniques ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/surgery
    Language German
    Publishing date 2024-02-09
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-698X
    ISSN (online) 2731-698X
    DOI 10.1007/s00104-024-02038-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Does Early Mobilization Following Resection of Spinal Intra-Dural Pathology Increase the Risk of Cerebrospinal Fluid Leaks?-A Dual-Center Comparative Effectiveness Research.

    Schwake, Michael / Krahwinkel, Sophia / Gallus, Marco / Schipmann, Stephanie / Maragno, Emanuele / Neuschmelting, Volker / Perrech, Moritz / Müther, Michael / Lenschow, Moritz

    Medicina (Kaunas, Lithuania)

    2024  Volume 60, Issue 1

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Humans ; Comparative Effectiveness Research ; Early Ambulation ; Plastic Surgery Procedures ; Spinal Neoplasms ; Cerebrospinal Fluid Leak/etiology
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina60010171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Book ; Online ; Thesis: Die diagnostische Facettengelenksinfiltration vor monosegmentaler lumbaler Fusionsoperation zur Prädiktion des Operationserfolgs im kurz- bis mittelfristigen Verlauf

    Karches, Leila [Verfasser] / Siewe, Jan Norbert [Gutachter] / Neuschmelting, Volker [Gutachter]

    Eine monozentrische, prospektive Beobachtungsstudie

    2021  

    Author's details Leila Karches ; Gutachter: Jan Norbert Siewe, Volker Neuschmelting
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Deutsche Zentralbibliothek für Medizin
    Publishing place Köln
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Book ; Online ; Thesis: Zeigen die Scores SINS nach Fisher et al., Tomita et al, Tokuhashi et al untereinander korrelierende Bewertungsfaktoren und Therapieempfehlungen bei Patienten mit spinalen Metastasen und/oder spinalen Instabilitäten - Eine retrospektive Analyse und ein systematisches Review.

    d'Aiello, Philipp-Simon Verfasser] / [Neuschmelting, Volker [Gutachter] / Zarghooni, Kourosh [Gutachter]

    2022  

    Author's details Philipp-Simon d'Aiello ; Gutachter: Volker Neuschmelting, Kourosh Zarghooni
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language German
    Publisher Universitäts- und Stadtbibliothek Köln
    Publishing place Köln
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  9. Article ; Online: Preoperative Performance Status Threshold for Favorable Surgical Outcome in Metastatic Spine Disease.

    Lenschow, Moritz / Lenz, Maximilian / Telentschak, Sergej / von Spreckelsen, Niklas / Sircar, Krishnan / Oikonomidis, Stavros / Kernich, Nikolaus / Walter, Sebastian G / Knöll, Peter / Perrech, Moritz / Goldbrunner, Roland / Eysel, Peer / Neuschmelting, Volker

    Neurosurgery

    2024  

    Abstract: Background and objectives: Surgical treatment is an integral component of multimodality management of metastatic spine disease but must be balanced against the risk of surgery-related morbidity and mortality, making tailored surgical counseling a ... ...

    Abstract Background and objectives: Surgical treatment is an integral component of multimodality management of metastatic spine disease but must be balanced against the risk of surgery-related morbidity and mortality, making tailored surgical counseling a clinical challenge. The aim of this study was to investigate the potential predictive value of the preoperative performance status for surgical outcome in patients with spinal metastases.
    Methods: Performance status was determined using the Karnofsky Performance Scale (KPS), and surgical outcome was classified as "favorable" or "unfavorable" based on postoperative changes in neurological function and perioperative complications. The correlation between preoperative performance status and surgical outcome was assessed to determine a KPS-related performance threshold.
    Results: A total of 463 patients were included. The mean age was 63 years (range: 22-87), and the mean preoperative KPS was 70 (range: 30-100). Analysis of clinical outcome in relation to the preoperative performance status revealed a KPS threshold between 40% and 50% with a relative risk of an unfavorable outcome of 65.7% in KPS ≤40% compared with the relative chance for a favorable outcome of 77.1% in KPS ≥50%. Accordingly, we found significantly higher rates of preserved or restored ambulatory function in KPS ≥50% (85.7%) than in KPS ≤40% (48.6%; P < .001) as opposed to a significantly higher risk of perioperative mortality in KPS ≤40% (11.4%) than in KPS ≥50% (2.1%, P = .012).
    Conclusion: Our results underline the predictive value of the KPS in metastatic spine patients for counseling and decision-making. The study suggests an overall clinical benefit of surgical treatment of spinal metastases in patients with a preoperative KPS score ≥50%, while a high risk of unfavorable outcome outweighing the potential clinical benefit from surgery is encountered in patients with a KPS score ≤40%.
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1227/neu.0000000000002941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1424: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 539: Show issues

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  10. Article: Cerebrospinal fluid leaks following intradural spinal surgery-Risk factors and clinical management.

    Lenschow, Moritz / Perrech, Moritz / Telentschak, Sergej / von Spreckelsen, Niklas / Pieczewski, Julia / Goldbrunner, Roland / Neuschmelting, Volker

    Frontiers in surgery

    2022  Volume 9, Page(s) 959533

    Abstract: Background: Cerebrospinal fluid leakage (CSFL) following spinal durotomy can lead to severe sequelae. However, while several studies have investigated accidental spinal durotomies, the risk factors and influence of clinical management in planned ... ...

    Abstract Background: Cerebrospinal fluid leakage (CSFL) following spinal durotomy can lead to severe sequelae. However, while several studies have investigated accidental spinal durotomies, the risk factors and influence of clinical management in planned durotomies remain unclear.
    Methods: We performed a retrospective analysis of all patients who underwent planned intradural spinal surgery at our institution between 2010 and 2020. Depending on the occurrence of a CSFL, patients were dichotomized and compared with respect to patient and case-related variables as well as dural closure technique, epidural drainage placement, and timing of mobilization.
    Results: A total of 351 patients were included. CSFL occurred in 4.8% of all cases. Surgical indication, tumor histology, location within the spine, previous intradural surgery, and medical comorbidities were not associated with an increased risk of CSFL development (all
    Conclusion: CSFL following planned durotomy pose a relevant and quantifiable complication risk of surgery that should be factored in during preoperative patient counseling. Our data could not demonstrate superiority of any particular dural closure technique but support the safety of both early mobilization within 24 h postoperatively and epidural drainage with reduced or no force of suction.
    Language English
    Publishing date 2022-09-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2022.959533
    Database MEDical Literature Analysis and Retrieval System OnLINE

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