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  1. Article ; Online: The Historian as Consultant: History of Medicine in the New Humanities in Chest Medicine Section.

    Neuss, Michael J

    Chest

    2021  Volume 159, Issue 4, Page(s) 1332–1333

    MeSH term(s) Consultants ; Health Personnel ; History of Medicine ; Humanities ; Humans ; Medicine ; Pulmonary Medicine
    Language English
    Publishing date 2021-04-06
    Publishing country United States
    Document type Editorial ; Historical Article ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2020.09.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Who Calls the Shots? A Legal and Historical Perspective on Vaccine Mandates.

    Fraser, Eric M / Neuss, Michael J

    Chest

    2022  Volume 162, Issue 3, Page(s) 659–663

    MeSH term(s) Humans ; Vaccination ; Vaccines
    Chemical Substances Vaccines
    Language English
    Publishing date 2022-09-02
    Publishing country United States
    Document type Editorial
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2022.04.142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Blood money: Harvey's De motu cordis (1628) as an exercise in accounting.

    Neuss, Michael J

    British journal for the history of science

    2018  , Page(s) 1–23

    Abstract: William Harvey's famous quantitative argument from De motu cordis (1628) about the circulation of blood explained how a small amount of blood could recirculate and nourish the entire body, upending the Galenic conception of the blood's motion. This paper ...

    Abstract William Harvey's famous quantitative argument from De motu cordis (1628) about the circulation of blood explained how a small amount of blood could recirculate and nourish the entire body, upending the Galenic conception of the blood's motion. This paper argues that the quantitative argument drew on the calculative and rhetorical skills of merchants, including Harvey's own brothers. Modern translations of De motu cordis obscure the language of accountancy that Harvey himself used. Like a merchant accounting for credits and debits, intake and output, goods and moneys, Harvey treated venous and arterial blood as essentially commensurate, quantifiable and fungible. For Harvey, the circulation (and recirculation) of blood was an arithmetical necessity. The development of Harvey's circulatory model followed shifts in the epistemic value of mercantile forms of knowledge, including accounting and arithmetic, also drawing on an Aristotelian language of reciprocity and balance that Harvey shared with mercantile advisers to the royal court. This paper places Harvey's calculations in a previously underappreciated context of economic crisis, whose debates focused largely on questions of circulation.
    Language English
    Publishing date 2018-04-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2017943-1
    ISSN 1474-001X ; 0007-0874
    ISSN (online) 1474-001X
    ISSN 0007-0874
    DOI 10.1017/S0007087418000250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Electronic health records and clinician burnout: A story of three eras.

    Johnson, Kevin B / Neuss, Michael J / Detmer, Don Eugene

    Journal of the American Medical Informatics Association : JAMIA

    2020  Volume 28, Issue 5, Page(s) 967–973

    Abstract: Objective: The study sought to provide physicians, informaticians, and institutional policymakers with an introductory tutorial about the history of medical documentation, sources of clinician burnout, and opportunities to improve electronic health ... ...

    Abstract Objective: The study sought to provide physicians, informaticians, and institutional policymakers with an introductory tutorial about the history of medical documentation, sources of clinician burnout, and opportunities to improve electronic health records (EHRs). We now have unprecedented opportunities in health care, with the promise of new cures, improved equity, greater sensitivity to social and behavioral determinants of health, and data-driven precision medicine all on the horizon. EHRs have succeeded in making many aspects of care safer and more reliable. Unfortunately, current limitations in EHR usability and problems with clinician burnout distract from these successes. A complex interplay of technology, policy, and healthcare delivery has contributed to our current frustrations with EHRs. Fortunately, there are opportunities to improve the EHR and health system. A stronger emphasis on improving the clinician's experience through close collaboration by informaticians, clinicians, and vendors can combine with specific policy changes to address the causes of burnout.
    Target audience: This tutorial is intended for clinicians, informaticians, policymakers, and regulators, who are essential participants in discussions focused on improving clinician burnout. Learners in biomedicine, regardless of clinical discipline, also may benefit from this primer and review.
    Scope: We include (1) an overview of medical documentation from a historical perspective; (2) a summary of the forces converging over the past 20 years to develop and disseminate the modern EHR; and (3) future opportunities to improve EHR structure, function, user base, and time required to collect and extract information.
    MeSH term(s) Burnout, Professional/history ; Documentation/history ; Electronic Health Records/history ; Electronic Health Records/organization & administration ; History, 18th Century ; History, 19th Century ; History, 20th Century ; History, 21st Century ; History, Ancient ; History, Medieval ; Medical Records ; Physicians/history
    Language English
    Publishing date 2020-10-29
    Publishing country England
    Document type Historical Article ; Journal Article
    ZDB-ID 1205156-1
    ISSN 1527-974X ; 1067-5027
    ISSN (online) 1527-974X
    ISSN 1067-5027
    DOI 10.1093/jamia/ocaa274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reversible, regional ST-segment elevation due to chylothorax.

    Brown, Sarah H / Neuss, Michael J / Heimlich, J Brett / Kronenberg, Marvin W

    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

    2021  Volume 27, Issue 1, Page(s) e12907

    Abstract: Chylothorax is an uncommon complication of thoracic surgery and, to our knowledge, has never been documented as a cause of dynamic ST-segment elevation (STE). A 63-year-old woman with history of right pneumonectomy presented with chest pain and regional ... ...

    Abstract Chylothorax is an uncommon complication of thoracic surgery and, to our knowledge, has never been documented as a cause of dynamic ST-segment elevation (STE). A 63-year-old woman with history of right pneumonectomy presented with chest pain and regional STE on 12-lead electrocardiogram (ECG). Normal troponin-I and a computed tomography (CT) scan showing a large right hemithoracic fluid collection indicated the unique cause of STE, which resolved after thoracentesis, was pericardial inflammation and cardiac compression from chylothorax. This case emphasizes nuances of ECG interpretation in the context of regional STE and explores the pathophysiology that links chylothorax with acute pericarditis.
    MeSH term(s) Arrhythmias, Cardiac ; Chest Pain ; Chylothorax/diagnostic imaging ; Chylothorax/etiology ; Electrocardiography ; Female ; Humans ; Middle Aged ; Retrospective Studies
    Language English
    Publishing date 2021-11-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1325530-7
    ISSN 1542-474X ; 1082-720X
    ISSN (online) 1542-474X
    ISSN 1082-720X
    DOI 10.1111/anec.12907
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Bleeding and thrombotic complications of pediatric liver transplant.

    Borst, Alexandra J / Sudan, Debra L / Wang, Laura A / Neuss, Michael J / Rothman, Jennifer A / Ortel, Thomas L

    Pediatric blood & cancer

    2018  Volume 65, Issue 5, Page(s) e26955

    Abstract: Background: Pediatric patients undergoing liver transplant are at significant risk for bleeding and thrombotic complications due to the complex nature of rebalanced hemostasis in patients with liver disease.: Methods/objectives: We reviewed records ... ...

    Abstract Background: Pediatric patients undergoing liver transplant are at significant risk for bleeding and thrombotic complications due to the complex nature of rebalanced hemostasis in patients with liver disease.
    Methods/objectives: We reviewed records of 92 pediatric liver and multivisceral transplant cases at Duke University Medical Center between January 2009 and December 2015. The goal was to define the nature and incidence of bleeding and thrombotic complications in this cohort and define potential risk factors.
    Results: There were 24 major bleeding events in 19 transplants (incidence 20.7%) and 30 thrombotic events in 23 transplants (incidence 25%). Five of the 10 retransplantations were for vascular thrombotic complications. Thirty-day mortality was 4.9%, and three of these four deaths were due to vascular thrombosis. No bleeding events led to retransplantation or mortality. Prophylactic aspirin was associated with decreased risk of thrombosis without increased bleeding. Prophylactic heparin did not increase bleeding risk. Laboratory assays predicted events poorly, apparently failing to capture the nuanced and dynamic interplay between pro- and anticoagulant factors in the posttransplant patient.
    Conclusions: Both bleeding and thrombosis are frequent in this population, but only thrombotic complications contributed to retransplantation and mortality. A standardized approach to coagulation testing and antithrombotic therapy may be useful in predicting and reducing adverse outcomes. Alternative approaches to monitoring hemostasis need to be prospectively investigated in this complex patient population.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Hemorrhage/etiology ; Humans ; Infant ; Infant, Newborn ; Liver Diseases/surgery ; Liver Transplantation/adverse effects ; Male ; Postoperative Complications ; Prognosis ; Risk Factors ; Thrombosis/etiology
    Language English
    Publishing date 2018-01-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.26955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Patients' Experiences With Staphylococcus aureus and Gram-negative Bacterial Bloodstream Infections: A Qualitative Descriptive Study and Concept Elicitation Phase To Inform Measurement of Patient-reported Quality of Life.

    King, Heather A / Doernberg, Sarah B / Miller, Julie / Grover, Kiran / Oakes, Megan / Ruffin, Felicia / Gonzales, Sarah / Rader, Abigail / Neuss, Michael J / Bosworth, Hayden B / Sund, Zoë / Drennan, Caitlin / Hill-Rorie, Jonathan M / Shah, Pratik / Winn, Laura / Fowler, Vance G / Holland, Thomas L

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 73, Issue 2, Page(s) 237–247

    Abstract: Background: Although Staphylococcus aureus and gram-negative bacterial bloodstream infections (SAB/GNB) cause substantial morbidity, little is known regarding patient perceptions' of their impact on quality of life (QOL). Guidance for assessing QOL and ... ...

    Abstract Background: Although Staphylococcus aureus and gram-negative bacterial bloodstream infections (SAB/GNB) cause substantial morbidity, little is known regarding patient perceptions' of their impact on quality of life (QOL). Guidance for assessing QOL and disease-specific measures are lacking. We conducted a descriptive qualitative study to gain an in-depth understanding of patients' experiences with SAB/GNB and concept elicitation phase to inform a patient-reported QOL outcome measure.
    Methods: We conducted prospective one-time, in-depth, semi-structured, individual, qualitative telephone interviews 6- 8 weeks following bloodstream infection with either SAB or GNB. Patients were enrolled in an institutional registry (tertiary academic medical center) for SAB or GNB. Interviews were audio-recorded, transcribed, and coded. Directed content analysis identified a priori and emergent themes. Theme matrix techniques were used to facilitate analysis and presentation.
    Results: Interviews were completed with 30 patients with SAB and 31 patients with GNB. Most patients were at or near the end of intravenous antibiotic treatment when interviewed. We identified 3 primary high-level concepts: impact on QOL domains, time as a critical index, and sources of variability across patients. Across both types of bloodstream infection, the QOL domains most impacted were physical and functional, which was particularly evident among patients with SAB.
    Conclusions: SAB/GNB impact QOL among survivors. In particular, SAB had major impacts on multiple QOL domains. A combination of existing, generic measures that are purposefully selected and disease-specific items, if necessary, could best capture these impacts. Engaging patients as stakeholders and obtaining their feedback is crucial to conducting patient-centered clinical trials and providing patient-centered care.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bacteremia/drug therapy ; Humans ; Patient Reported Outcome Measures ; Prospective Studies ; Quality of Life ; Sepsis/drug therapy ; Staphylococcal Infections/drug therapy ; Staphylococcus aureus
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2020-06-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa611
    Database MEDical Literature Analysis and Retrieval System OnLINE

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