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  1. Article ; Online: Administrative data ICD-10 diagnostic codes identifies most lab-confirmed SARS-CoV-2 admissions but misses many discharged from the Emergency Department.

    Moura, Cristiano S / Morrison, Laurie J / Hohl, Corinne M / Grant, Lars / Pilote, Louise / Neville, Autumn / Hau, Jeffrey P / Bernatsky, Sasha

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6008

    Abstract: We estimated the operating characteristics of ICD-10 code U07.1, introduced by the World Health Organization in 2020, to identify lab-confirmed SARS-CoV-2. CCEDRRN is a national research registry of adults (March 2020-August 2021) with suspected/ ... ...

    Abstract We estimated the operating characteristics of ICD-10 code U07.1, introduced by the World Health Organization in 2020, to identify lab-confirmed SARS-CoV-2. CCEDRRN is a national research registry of adults (March 2020-August 2021) with suspected/confirmed SARS-CoV-2 identified in Canadian emergency departments (EDs) using chart review (symptoms, clinical information, and lab test results including SARS-CoV-2 polymerase chain reaction, PCR results). CCEDRRN data were linked to administrative hospitalization discharge and ED ICD-10 diagnostic codes (accessed centrally via the Canadian Institute for Health Information). We identified ICD-10 diagnostic codes in CCEDRRN participants. We defined lab-confirmed SARS-CoV-2 based on at least one positive PCR in the 0-14 days before the ED presentation and/or during hospitalization (in those admitted from ED). We performed separate analyses for CCEDRRN participants discharged from ED and those hospitalized from the ED. Additional analyses were stratified by province, sex, age, and (for hospitalized patients) timing of the first PCR test. The sensitivity of ICD-10 code U07.1 for a positive SARS-CoV-2 test was 93.6% (95% CI 93.0-94.1%) in those hospitalized from ED and 83.0% (95% CI 82.1-83.9%) in those discharged from the ED. Sensitivity was similar across provinces and demographics, but in each stratified analysis, values were higher in those hospitalized versus those discharged from ED. The ICD-10 diagnostic code for U07.1 within administrative data identified most lab-confirmed SARS-CoV-2 within persons hospitalized from ED, although a significant number of cases discharged from ED were missed. This should be considered when using administrative data for research and public health planning.
    MeSH term(s) Adult ; Humans ; SARS-CoV-2 ; Patient Discharge ; COVID-19 ; International Classification of Diseases ; Canada ; Emergency Service, Hospital ; Hospitalization ; COVID-19 Testing
    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-49501-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Validity of hospital diagnostic codes to identify SARS-CoV-2 infections in reference to polymerase chain reaction results: a descriptive study.

    Moura, Cristiano S / Neville, Autumn / Liao, Fangming / Wen, Bijun / Razak, Fahad / Roberts, Surain / Verma, Amol A / Bernatsky, Sasha

    CMAJ open

    2023  Volume 11, Issue 5, Page(s) E982–E987

    Abstract: Background: In 2020, : Methods: GEMINI assembles hospitalization data (including administrative ICD-10 discharge diagnostic codes, laboratory results and demographic data) from hospitals in Ontario, Canada. We studied adults (age ≥ 18 yr) admitted ... ...

    Abstract Background: In 2020,
    Methods: GEMINI assembles hospitalization data (including administrative ICD-10 discharge diagnostic codes, laboratory results and demographic data) from hospitals in Ontario, Canada. We studied adults (age ≥ 18 yr) admitted during 2020 and tested at least once for SARS-CoV-2 via polymerase chain reaction (PCR) during (or within 48 h before) hospitalization. With PCR results as the reference standard, we calculated sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for ICD-10 code U07.1 hospital discharge diagnostic codes. Analyses were stratified by demographic data, calendar period and timing of the first test (within or after 48 h of hospital admission).
    Results: In 11 852 hospitalizations with at least 1 SARS-CoV-2 PCR test, 444 (3.7%) were positive. The sensitivity of code U07.1 to identify SARS-CoV-2 infection was 97.8%, specificity was 99.5%, PPV was 88.2% and NPV was 99.9%. Operating characteristics were similar in most stratified analyses, but the specificity and PPV were lower if the first SARS-CoV-2 test was done more than 48 hours after admission.
    Interpretation: The sensitivity, specificity, PPV and NPV of code U07.1 were high. This supports using code U07.1 to identify SARS-CoV-2 infection in hospitalization data.
    Language English
    Publishing date 2023-10-24
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2701622-5
    ISSN 2291-0026 ; 2291-0026
    ISSN (online) 2291-0026
    ISSN 2291-0026
    DOI 10.9778/cmajo.20230033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Response to Middleton KR et als. Yoga and SLE.

    Lee, Jennifer / Pineau, Christian A / Da Costa, Deborah / Clarke, Ann E / Fortin, Paul R / Neville, Carolyn / Neville, Autumn / Bernatsky, Sasha

    Complementary therapies in medicine

    2019  Volume 43, Page(s) 311

    MeSH term(s) Humans ; Lupus Erythematosus, Systemic ; Meditation ; Students ; Yoga
    Language English
    Publishing date 2019-02-28
    Publishing country Scotland
    Document type Letter ; Comment
    ZDB-ID 1155895-7
    ISSN 1873-6963 ; 0965-2299
    ISSN (online) 1873-6963
    ISSN 0965-2299
    DOI 10.1016/j.ctim.2019.02.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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