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  1. Article ; Online: The yield of tuberculosis contact investigation on relapsed TB patients and analysis of associated risk factors: Singapore's experience.

    Kyaw, Win M / Lim, Leo K-Y / Tay, Jun Y / Cutter, Jeffery L / Ng, Deborah H L

    Epidemiology and infection

    2024  Volume 152, Page(s) e26

    Abstract: The yield of contact investigation on relapsed tuberculosis (TB) cases can guide strategies and resource allocation in the TB control programme. We conducted a retrospective cohort study to review the yield of contact investigation in relapsed TB cases ... ...

    Abstract The yield of contact investigation on relapsed tuberculosis (TB) cases can guide strategies and resource allocation in the TB control programme. We conducted a retrospective cohort study to review the yield of contact investigation in relapsed TB cases and identify factors associated with TB infection (TBI) among close contacts of relapsed TB cases notified between 2018 and 2022 in Singapore. TB infection positivity was higher among contacts of relapsed cases which were culture-positive
    MeSH term(s) Humans ; Contact Tracing ; Retrospective Studies ; Singapore/epidemiology ; Tuberculosis/epidemiology ; Tuberculosis/diagnosis ; Mycobacterium tuberculosis ; Latent Tuberculosis/epidemiology
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268824000104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Un I Zs.271: Show issues Location:
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  2. Article ; Online: Implementation of national whole-genome sequencing of

    Lim, Ansel Yi Herh / Ang, Michelle L T / Cho, Sharol S L / Ng, Deborah H L / Cutter, Jeffery / Lin, Raymond T P

    Microbial genomics

    2023  Volume 9, Issue 11

    Abstract: The National Tuberculosis Programme (NTBP) monitors the occurrence and spread of tuberculosis (TB) and multidrug-resistant TB (MDR-TB) in Singapore. Since 2020, whole-genome sequencing (WGS) ... ...

    Abstract The National Tuberculosis Programme (NTBP) monitors the occurrence and spread of tuberculosis (TB) and multidrug-resistant TB (MDR-TB) in Singapore. Since 2020, whole-genome sequencing (WGS) of
    MeSH term(s) Animals ; Horses ; Mycobacterium tuberculosis ; Antitubercular Agents/pharmacology ; Microbial Sensitivity Tests ; Public Health ; Singapore/epidemiology ; Drug Resistance, Multiple, Bacterial/genetics ; Tuberculosis, Multidrug-Resistant/epidemiology ; Tuberculosis, Multidrug-Resistant/microbiology ; Tuberculosis/epidemiology
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2023-11-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835258-0
    ISSN 2057-5858 ; 2057-5858
    ISSN (online) 2057-5858
    ISSN 2057-5858
    DOI 10.1099/mgen.0.001139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Survival and complications with a surgical approach in advanced hypopharyngeal cancer.

    Galeano Machuca, Maria Paz / Ng, Deborah L / Terng, Shyuang-Der / Wu, Wen-Ching / Cheng, Chih-Tao

    Journal of surgical oncology

    2021  Volume 123, Issue 7, Page(s) 1540–1546

    Abstract: Background and objectives: The treatment paradigm for advanced hypopharyngeal cancer has shifted from surgical approaches to organ preservation. However, recent studies indicated that surgical approaches may be associated with better survival rates. ... ...

    Abstract Background and objectives: The treatment paradigm for advanced hypopharyngeal cancer has shifted from surgical approaches to organ preservation. However, recent studies indicated that surgical approaches may be associated with better survival rates. This study aimed to conduct a head-to-head comparison of survival outcomes and complications with surgical versus nonsurgical approaches using a nationwide database.
    Methods: Using a nationwide data set, we gathered 2196 propensity score-matched patients with stage III/IVa hypopharyngeal cancer. We compared survival rates and complications among patients with surgical and nonsurgical cancer treatment.
    Results: Patients with stage III and IVa hypopharyngeal cancer who underwent initial surgery had significantly better 5-year overall survival and disease-free survival rates compared to their nonsurgical counterparts. There were no significant differences in long-term complications with regard to swallowing.
    Conclusions: These results suggest that patients who underwent initial surgery for advanced hypopharyngeal cancers had better survival rates and equivalent long-term function.
    MeSH term(s) Adult ; Aged ; Disease-Free Survival ; Female ; Humans ; Hypopharyngeal Neoplasms/mortality ; Hypopharyngeal Neoplasms/pathology ; Hypopharyngeal Neoplasms/surgery ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neck Dissection/methods ; Neck Dissection/mortality ; Neck Dissection/statistics & numerical data ; Neoplasm Staging ; Postoperative Complications/epidemiology ; Propensity Score ; Registries ; Squamous Cell Carcinoma of Head and Neck/mortality ; Squamous Cell Carcinoma of Head and Neck/pathology ; Squamous Cell Carcinoma of Head and Neck/surgery ; Taiwan/epidemiology
    Language English
    Publishing date 2021-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.26440
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 706: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: The Impact of Nurses' Uniforms on Nurse-Patient Interactions: Patients' Perspectives.

    Tam, Wai Yi / Ng, Deborah Li Li / Kowitlawakul, Yanika

    The Journal of nursing administration

    2018  Volume 48, Issue 10, Page(s) 526–532

    Abstract: Objectives: The aim of this study was to explore patients' perceptions toward the nursing uniforms used in a hospital in Singapore and how different uniforms impact nurse-patient interactions.: Background: Nursing uniforms act as a form of nonverbal ... ...

    Abstract Objectives: The aim of this study was to explore patients' perceptions toward the nursing uniforms used in a hospital in Singapore and how different uniforms impact nurse-patient interactions.
    Background: Nursing uniforms act as a form of nonverbal communication. However, implications of the increasing variety of nursing uniforms on patients' perceptions of nurses and nurse-patient interactions are unexplored.
    Methods: An exploratory qualitative study design using semistructured interviews was adopted for the study. Twenty-one patients agreed to be interviewed. An audio recorder was used during data collection. The thematic analysis method was used for data analysis.
    Results: Four major themes were identified: identity, subjectivity, suitability, and inconsequential. Nurses' uniform was regarded as a representation of identity. Suitability of the uniform for nurses was a main concern for patients. However, nurses' uniforms were inconsequential to nurse-patient interactions.
    Conclusion: Patients' perceptions of nurses' uniforms were highly subjective and have no substantial impact on nurse-patient interactions.
    MeSH term(s) Attitude to Health ; Clothing ; Female ; Humans ; Inpatients/psychology ; Male ; Nurse-Patient Relations ; Patient Satisfaction/statistics & numerical data ; Qualitative Research ; Singapore ; Social Perception
    Language English
    Publishing date 2018-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193141-6
    ISSN 1539-0721 ; 1539-073X ; 0002-0443
    ISSN (online) 1539-0721 ; 1539-073X
    ISSN 0002-0443
    DOI 10.1097/NNA.0000000000000661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1008: Show issues Location:
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  5. Article: Into the shadow: a reflection on the stigma of human immunodeficiency virus (HIV) in Singapore.

    Ng, Deborah H L

    Annals of the Academy of Medicine, Singapore

    2012  Volume 41, Issue 12, Page(s) 625–627

    MeSH term(s) HIV Infections/economics ; HIV Infections/psychology ; HIV Infections/transmission ; Humans ; Refusal to Treat ; Singapore ; Social Stigma
    Language English
    Publishing date 2012-12-04
    Publishing country Singapore
    Document type Letter
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2420: Show issues Location:
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  6. Article: Paterson-Brown Kelly Syndrome (also commonly known as Plummer-Vinson Syndrome).

    Goh, Wilson Guo Wei / Ng, Deborah Chieh Yih / Ng, Jun Xuan / Lim, Kheng Tian

    Clinical case reports

    2020  Volume 8, Issue 11, Page(s) 2316–2317

    Abstract: The dysphagia in this condition is usually associated with iron deficiency anemia and esophageal webs. Iron supplementation and regular surveillance are required for monitoring of malignant transformation into esophageal squamous cell carcinoma. ...

    Abstract The dysphagia in this condition is usually associated with iron deficiency anemia and esophageal webs. Iron supplementation and regular surveillance are required for monitoring of malignant transformation into esophageal squamous cell carcinoma.
    Language English
    Publishing date 2020-07-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.3127
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  7. Article ; Online: Short-term Weight Trajectory of Severely Obese Individuals With and Without Pathogenic Satiety-Regulation Melanocortin 3/4 Receptor (MC3/4R) Mutations From a Multi-ethnic Asian Large Bariatric Surgery Program.

    Lim, Joel Guanyi / Moh, Angela / Pandian, Bhuvaneswari / Ubeynarayana, Chalani Udhyami / Lim, Nathaniel Guanning / Tan, Bo Chuan / Ng, Deborah / Subramaniam, Tavintharan / Cheng, Anton / Lim, Su Chi

    Journal of investigative medicine high impact case reports

    2023  Volume 11, Page(s) 23247096231168108

    Abstract: The melanocortin (3 or 4) receptor (MC3/4R) is involved in regulating satiety and body weight. Therefore, pathogenic mutation in MC3/4R is associated with severe obesity, for which bariatric surgery is one of the treatment options. However, there is ... ...

    Abstract The melanocortin (3 or 4) receptor (MC3/4R) is involved in regulating satiety and body weight. Therefore, pathogenic mutation in MC3/4R is associated with severe obesity, for which bariatric surgery is one of the treatment options. However, there is limited data on whether individuals with MC3/4R mutation will have differential weight response to surgery, especially among the Asian populations-the epi-center of the evolving global obesity epidemic. From our large prospective Obesity-Metabolism & Intervention Cohort Study (OMICS; N = 654, recruited between 2007 and 2022), 5 individuals with pathogenic MC3/4R mutations ("case") were identified using candidate-genes panel next-generation sequencing (Illumina iSeq). These subjects were carefully propensity score-matched (baseline body mass index [BMI], age, sex, ethnicity, proportion with diabetes, type of bariatric surgery) in a 1:4 ratio to other controls. We performed linear mixed model analysis (for repeated measurements) to compare their longitudinal weight trajectories (percentage total weight loss, %TWL) over 12 months. The 5 cases with MC3/4R mutations were 48 ± 11 years, BMI 40.8 ± 11.2 kg/m
    MeSH term(s) Male ; Humans ; Body-Weight Trajectory ; Receptor, Melanocortin, Type 3/genetics ; Cohort Studies ; Prospective Studies ; Obesity/genetics ; Obesity/surgery ; Bariatric Surgery ; Melanocortins ; Mutation
    Chemical Substances Receptor, Melanocortin, Type 3 ; Melanocortins
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Case Reports
    ZDB-ID 2710326-2
    ISSN 2324-7096 ; 2324-7096
    ISSN (online) 2324-7096
    ISSN 2324-7096
    DOI 10.1177/23247096231168108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: "Locked in a cage"-A case of dengue virus 4 encephalitis.

    Ng, Deborah H L / Sadarangani, Sapna P

    PLoS neglected tropical diseases

    2017  Volume 11, Issue 5, Page(s) e0005369

    MeSH term(s) Acyclovir/therapeutic use ; Antiviral Agents/therapeutic use ; Dengue/drug therapy ; Dengue/pathology ; Dengue/virology ; Encephalitis, Viral/drug therapy ; Encephalitis, Viral/pathology ; Encephalitis, Viral/virology ; Endemic Diseases ; Female ; Humans ; Middle Aged
    Chemical Substances Antiviral Agents ; Acyclovir (X4HES1O11F)
    Language English
    Publishing date 2017-05-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2727
    ISSN (online) 1935-2735
    ISSN 1935-2727
    DOI 10.1371/journal.pntd.0005369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Social media marketing all-in-one for dummies

    Zimmerman, Jan / Ng, Deborah

    (For dummies)

    2013  

    Abstract: Your business can't afford to be left behind, and if you need a guide through the social media maze, this book is just what you're looking for! Learn how to take full advantage of social media marketing while boosting your social media ... ...

    Author's details by Jan Zimmerman and Deborah Ng
    Series title For dummies
    Abstract Your business can't afford to be left behind, and if you need a guide through the social media maze, this book is just what you're looking for! Learn how to take full advantage of social media marketing while boosting your social media savvy
    Keywords Internet advertising ; Internet marketing ; Online social networks ; Social marketing ; Social media/Marketing
    Language English
    Size xxii, 770 p, ill, 24 cm
    Edition 2nd ed
    Publisher Wiley
    Publishing place Hoboken, NJ
    Document type Book
    Note Includes index
    ISBN 1118215524 ; 1118505409 ; 9781118215524 ; 9781118285091 ; 9781118282304 ; 9781118505403 ; 1118285093 ; 1118282302
    Database Former special subject collection: coastal and deep sea fishing

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  10. Article: SIR Flat CAP (Safety In Radiology - Flat-Packed Compact Airborne Precaution): A Low-Cost, Portable, Negative-Pressure Isolation Barrier Shield for Protecting Frontline Healthcare Workers.

    Ong, Shao J / Renfrew, Ian / Khoo, Deborah X / Choong, Denise A / Koh, Hui L / Ng, Deborah S / Teo, Lycia / Lee, Joseph K / Yuen, Linda / Chia, Koon Liang / Chen, Priscilla X / Teo, Yi Ming / Ang, Bertrand / Quek, Swee Tian

    Cureus

    2023  Volume 15, Issue 10, Page(s) e46345

    Abstract: Introduction Multiple barrier shields have been described since the start of the COVID-19 pandemic. Most of these are bulky and designed for use in the main anesthetic or radiology departments. We developed a portable, negative-pressure barrier shield ... ...

    Abstract Introduction Multiple barrier shields have been described since the start of the COVID-19 pandemic. Most of these are bulky and designed for use in the main anesthetic or radiology departments. We developed a portable, negative-pressure barrier shield designed specifically for portable ultrasound examinations. A novel supine cough generation model was developed together with a reverse qualitative fit test to simulate real-world aerosol droplet generation and dispersion for evaluating the effectiveness of the barrier shield. We report the technical specifications of this design, named "SIR Flat CAP" from Safety In Radiology - Flat-packed Compact Airborne Precaution, as well as its performance in reducing the spread of droplets and aerosols.  Methods The barrier shield was constructed using 1 mm acrylic panels, clear packing tape, foam double-sided tape, and surgical drapes. Negative pressure was provided via hospital wall suction. A supine cough generation model was developed to simulate cough droplet dispersal. A reverse qualitative fit test was used to assess for airborne transmission of microdroplets. Results The supine cough generation model was able to replicate similar results to previously reported supine human cough generation dispersion. The use of the barrier shield with negative-pressure suction prevented the escape of visible droplets, and no airborne microdroplets were detected by reverse qualitative fit testing from the containment area. Conclusions The barrier shield significantly reduces the escape of visible and airborne droplets from the containment area, providing an additional layer of protection to front-line sonographers.
    Language English
    Publishing date 2023-10-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.46345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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