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  1. Article: Placental Site Trophoblastic Tumour Mimicking Placenta Previa.

    Bukar, Mohammed / Kawuwa, Mohammed Bello / Nggada, H A / Pindiga, H U / Malgwi, Adamu

    The Nigerian postgraduate medical journal

    2024  Volume 31, Issue 1, Page(s) 81–83

    Abstract: Abstract: We present a 42-year-old Nigerian woman who had three previous caesarean sections and is being managed conservatively for placenta previa. She underwent a caesarean hysterectomy on account of uncontrollable bleeding, and histopathology ... ...

    Abstract Abstract: We present a 42-year-old Nigerian woman who had three previous caesarean sections and is being managed conservatively for placenta previa. She underwent a caesarean hysterectomy on account of uncontrollable bleeding, and histopathology revealed a placental site trophoblastic tumour.
    MeSH term(s) Pregnancy ; Female ; Humans ; Adult ; Placenta ; Placenta Previa/surgery ; Trophoblastic Tumor, Placental Site ; Nigeria ; Uterine Neoplasms ; Hysterectomy
    Language English
    Publishing date 2024-02-07
    Publishing country Nigeria
    Document type Case Reports ; Journal Article
    ZDB-ID 2171096-X
    ISSN 1117-1936
    ISSN 1117-1936
    DOI 10.4103/npmj.npmj_236_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Helicobacter pylori indyspeptic Nigerians.

    Olokoba, A B / Apari, E / Salawu, F K / Nggada, H A

    West African journal of medicine

    2013  Volume 32, Issue 4, Page(s) 277–280

    Abstract: Background: Dyspepsia is a common gastrointestinal disorder, and is the most common indication for upper gastrointestinal endoscopy. Helicobacter pylori is a significant aetiological factor in acid peptic diseases and gastric cancer. Detection of this ... ...

    Abstract Background: Dyspepsia is a common gastrointestinal disorder, and is the most common indication for upper gastrointestinal endoscopy. Helicobacter pylori is a significant aetiological factor in acid peptic diseases and gastric cancer. Detection of this organism during upper gastrointestinal endoscopy has become standard clinical practice. Data is scanty from North-Eastern Nigeria on the subject.
    Objectives: To determine the prevalence of Helicobacter pylori among dyspeptic patients, and alsoto find out the association of H. pylori and degree of activity in chronic gastritis.
    Methods: This is a hospital-based cross sectional study which was carried out at the Endoscopy unit of Federal Medical Centre, Yola and Histopathology unit, University of Maiduguri Teaching Hospital, Maiduguri from November, 2006 to May, 2010. Patients with dyspepsia who underwent upper gastrointestinal endoscopy as part of their work-up, also had endoscopic biopsies taken from the antral portions of their stomach. The biopsy specimens were fixed in 10% formalin and transported from Yola to Maiduguri by courier for processing.
    Results: Three hundred and forty-nine patients comprising 152(43.6%) males and 197(56.4%) females with dyspepsia had upper gastrointestinal endoscopy. Their age ranged between 14 and 103 years with a median of 44.1 years. A prevalence rate of 56.7% for Helicobacter pylori was found.Helicobacter pylori associated with severe activity accounted for 80.3%; moderate activity- 57.5%; mild activity - 20% and normal gastric mucosa- 9.1%.
    Conclusion: There is a high prevalence of Helicobacter pylori among patients with dyspepsia, and a strong association between H. pylori and chronic gastritis with severe activity.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chronic Disease ; Cross-Sectional Studies ; Dyspepsia/microbiology ; Female ; Gastritis/microbiology ; Helicobacter Infections/epidemiology ; Helicobacter pylori ; Humans ; Male ; Middle Aged ; Nigeria ; Prevalence ; Young Adult
    Language French
    Publishing date 2013-10
    Publishing country Nigeria
    Document type Journal Article
    ZDB-ID 1132088-6
    ISSN 0189-160X
    ISSN 0189-160X
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  3. Article: Cutaneous metastasis from hepatocellular carcinoma: a rare presentation and review of the literature.

    Nggada, H A / Ajayi, N A

    African journal of medicine and medical sciences

    2006  Volume 35, Issue 2, Page(s) 181–182

    Abstract: A 53-year-old male Nigerian with a rare cutaneous metastasis and a late manifestation of hepatocellular carcinoma is presented. The skin nodules were umbilicated, painless. firm and spread on the chest, abdomen and back. Ultrasonography showed a huge ... ...

    Abstract A 53-year-old male Nigerian with a rare cutaneous metastasis and a late manifestation of hepatocellular carcinoma is presented. The skin nodules were umbilicated, painless. firm and spread on the chest, abdomen and back. Ultrasonography showed a huge mass in the right lobe of the liver. Fine needle aspiration cytology of the liver revealed hepatocellular carcinoma and the skin nodule, metastatic carcinoma of hepatic origin. The immunological marker HBsAg was positive while Anti-HCV Ab and alpha-feto-protein were negative. Patient died and consent for post-mortem examination was refused.
    MeSH term(s) Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/pathology ; Humans ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/pathology ; Male ; Middle Aged ; Skin Neoplasms/pathology ; Skin Neoplasms/secondary ; Ultrasonography
    Language English
    Publishing date 2006-06
    Publishing country Nigeria
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 429127-x
    ISSN 0309-3913 ; 1116-4077
    ISSN 0309-3913 ; 1116-4077
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  4. Article: Nasopharyngeal cancer in North--Eastern Nigeria: clinical trends.

    Garandawa, H I / Ahmad, B M / Nggada, H A

    Nigerian journal of clinical practice

    2009  Volume 12, Issue 4, Page(s) 379–382

    Abstract: Background: Nasopharyngeal cancer is the malignancy of the posterior aspect of the nose called Nasopharynx. It is one of the most difficult diseases to diagnose at an early stage.: Aim: To determine prevalence, clinical trends and histopathological ... ...

    Abstract Background: Nasopharyngeal cancer is the malignancy of the posterior aspect of the nose called Nasopharynx. It is one of the most difficult diseases to diagnose at an early stage.
    Aim: To determine prevalence, clinical trends and histopathological types of Nasopharyngeal cancer in Maiduguri, North Eastern Nigeria.
    Patients and method: Fifteen year retrospective evaluation of patient's case notes and cancer registry records of 40 patients with histologically confirmed nasopharyngeal cancer between 1991-2005.
    Results: Nasopharyngeal cancers constituted 35.1% of all malignancies of ear, nose, throat during the study period. The M:F was 2.1-1, the mean age was 39(+/- 16.5) years and a peak age group and its occurrence of 40-49 years. The commonest symptom at presentation were cervical lymphadenopathy (72.5%), rhinorrhoea (55%), epistaxis(45%). The commonest histological type was squamous cell carcinoma(92.5%). Patients who received chemotherapy in addition to radiotherapy and higher symptom free period.
    Conclusion: Cancer is a difficult disease to diagnose at an stage. A meticulous ear, nose and throat examination and thorough evaluation of nasal symptoms with associated cervical lymphadenopathy may lead to an early diagnosis of nasopharyngeal cancer's.
    MeSH term(s) Adolescent ; Adult ; Age Distribution ; Aged ; Carcinoma, Squamous Cell/epidemiology ; Carcinoma, Squamous Cell/pathology ; Child ; Female ; Humans ; Lymphoma, Non-Hodgkin/epidemiology ; Lymphoma, Non-Hodgkin/pathology ; Male ; Middle Aged ; Nasopharyngeal Neoplasms/epidemiology ; Nasopharyngeal Neoplasms/pathology ; Nigeria/epidemiology ; Prevalence ; Registries ; Retrospective Studies ; Rhabdomyosarcoma/epidemiology ; Rhabdomyosarcoma/pathology ; Risk Factors ; Young Adult
    Language English
    Publishing date 2009-12
    Publishing country India
    Document type Journal Article
    ZDB-ID 1458330-6
    ISSN 1119-3077
    ISSN 1119-3077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A histopathological analysis of thyroid diseases in Ile-ife, Nigeria. a review of 274 cases.

    Nggada, H A / Ojo, O S / Adelusola, K O

    The Nigerian postgraduate medical journal

    2008  Volume 15, Issue 1, Page(s) 47–51

    Abstract: Objective: To describe the spectrum of histopathological features of thyroid diseases; analyse the occurrence of each of the types and to compare the findings with those from previous studies done in Nigeria and elsewhere.: Materials and methods: A ... ...

    Abstract Objective: To describe the spectrum of histopathological features of thyroid diseases; analyse the occurrence of each of the types and to compare the findings with those from previous studies done in Nigeria and elsewhere.
    Materials and methods: A retrospective study of thyroid lesions seen at the OAUTHC Histopathology Department during a 10-year period between 1988 and 1997.
    Results: The 274 surgical thyroid specimens received during the study period came from 235 (85.8%) females and 39 (14.2%) males giving a female: male ratio of 6:1. Colloid goiter accounted for about 75% of cases with an average age of occurrence of 40.7 years. Only 1.8% showed features of toxic goiter and thyroiditis each. The adenomas constituted about 6% while carcinomas constituted about 11% of cases respectively. Adenomas occurred almost a decade earlier than carcinomas. Follicular carcinoma was the commonest thyroid cancer seen in this study.
    Conclusion: This study shows that the commonest thyroid disease in Ile-Ife is colloid goiter, which is a preventable disease. Thus, public health measures such as iodination of salt and health education are called for to reduce the occurrence of this disease.
    MeSH term(s) Adolescent ; Adult ; Child ; Female ; Humans ; Male ; Middle Aged ; Nigeria/epidemiology ; Retrospective Studies ; Thyroid Diseases/epidemiology ; Thyroid Diseases/pathology ; Thyroid Diseases/therapy
    Language English
    Publishing date 2008-03
    Publishing country Nigeria
    Document type Journal Article ; Review
    ZDB-ID 2171096-X
    ISSN 1117-1936
    ISSN 1117-1936
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  6. Article: Schistosomiasis of the appendix in Maiduguri.

    Gali, B M / Nggada, H A / Eni, E U

    Tropical doctor

    2006  Volume 36, Issue 3, Page(s) 162–163

    Abstract: We retrospectively studied 27 histologically diagnosed cases of schistosomiasis of the appendix at the University of Maiduguri Teaching Hospital between January 1994 and December 2003. Of 1183 cases of appendices histologically examined, schistosomiasis ... ...

    Abstract We retrospectively studied 27 histologically diagnosed cases of schistosomiasis of the appendix at the University of Maiduguri Teaching Hospital between January 1994 and December 2003. Of 1183 cases of appendices histologically examined, schistosomiasis was seen in 27 (2.3%).
    MeSH term(s) Adolescent ; Adult ; Animals ; Appendectomy ; Appendicitis/parasitology ; Appendix/parasitology ; Female ; Humans ; Male ; Middle Aged ; Schistosoma haematobium ; Schistosoma mansoni ; Schistosomiasis haematobia/complications ; Schistosomiasis haematobia/parasitology ; Schistosomiasis mansoni/complications ; Schistosomiasis mansoni/parasitology
    Language English
    Publishing date 2006-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1258/004947506777978073
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  7. Article: Prostate cancer in Maiduguri.

    Yawe, K T / Tahir, M B / Nggada, H A

    West African journal of medicine

    2006  Volume 25, Issue 4, Page(s) 298–300

    Abstract: Background: Prostate cancer is the sixth most important cancer in the world, and its incidence in blacks has been on the increase. It is a very important cause of morbidity and mortality. In North-eastern Nigeria, reports on prostate cancer have been ... ...

    Abstract Background: Prostate cancer is the sixth most important cancer in the world, and its incidence in blacks has been on the increase. It is a very important cause of morbidity and mortality. In North-eastern Nigeria, reports on prostate cancer have been scarce. The aim of this paper is to highlight the clinico-pathological features and management of prostate cancer in north-eastern Nigeria.
    Study design: The clinical records and histopathological slides of all prostate cancer patients seen at the UMTH from January 1987 to December 2004 were retrospectively reviewed. The total number of cancers diagnosed during this period was also obtained from the cancer registry.
    Results: Prostate cancer was seen in 165 patients and accounted for 6.15% of cancers diagnosed in this hospital. Majority of patients (56%) were aged 65 years and below and most presenting symptoms were similar to those of benign prostatic hypertrophy (BPH). The diagnosis was made in most cases on the basis of DRE, USS, PSA, and confirmed by trucut prostatic biopsy. Since most cases were advanced, the most frequent palliative treatment was subcapsular orchidectomy, which was psychologically satisfying to patients. Follow-up was very poor, only 26% at 3 years.
    Conclusion: Since most patients present late we conclude that prostate cancer should be suspected in men of 50 years and above who present with symptoms of prostatism and should be investigated promptly. Furthermore, aggressive screening of men in this age group would facilitate early diagnosis.
    MeSH term(s) Aged ; Aged, 80 and over ; Humans ; Male ; Middle Aged ; Nigeria/epidemiology ; Orchiectomy ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/surgery ; Retrospective Studies
    Language English
    Publishing date 2006-10
    Publishing country Nigeria
    Document type Journal Article
    ZDB-ID 1132088-6
    ISSN 0189-160X
    ISSN 0189-160X
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  8. Article: Histopathological findings in nephrectomy specimens--A review of 42 cases.

    Nggada, H A / Eni, U E / Nwankwo, E A

    The Nigerian postgraduate medical journal

    2006  Volume 13, Issue 3, Page(s) 244–246

    Abstract: Objective: This study aims at determining the histopathological findings in nephrectomy specimens in the University of Maiduguri Teaching Hospital.: Methods: A retrospective study of all cases of nephrectomies in UMTH between January 1993 and ... ...

    Abstract Objective: This study aims at determining the histopathological findings in nephrectomy specimens in the University of Maiduguri Teaching Hospital.
    Methods: A retrospective study of all cases of nephrectomies in UMTH between January 1993 and December 2003.
    Results: There were 42 cases of unilateral nephrectomies, 26 (61.9%) males and 16 (38.1.9%) females giving a ratio of 1.6:1. Of these, 23 (54.8%) were benign and 19(45.2%) malignant. Chromic interstitial/pyelonephritis was the commonest indication for nephrectomy and this accounted for 28.6% of all cases. Nephroblastoma, the second commonest, accounted for 23.8% of all cases and is the major malignant indication for nephrectomies. Renal cell carcinoma and hydronephrosis accounted for 7(16.7%) cases each; polycystic kidney, transitional cell carcinoma and non-Hodgkin's lymphoma.
    Conclusion: There is need to emphasise the importance of early diagnosis and proper treatment of urinary tract infections, since chronic interstitial/pyelonephritis is the commonest indication for nephrectomy in our environment. This will go long way in reducing the rate nephrectomies on our patients.
    MeSH term(s) Adolescent ; Adult ; Carcinoma, Renal Cell/pathology ; Child ; Female ; Humans ; Hydronephrosis/pathology ; Kidney Neoplasms/pathology ; Male ; Middle Aged ; Nephrectomy ; Polycystic Kidney Diseases/pathology ; Pyelonephritis/pathology ; Retrospective Studies ; Wilms Tumor/pathology
    Language English
    Publishing date 2006-09
    Publishing country Nigeria
    Document type Journal Article
    ZDB-ID 2171096-X
    ISSN 1117-1936
    ISSN 1117-1936
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  9. Article: Post-thyroidectomy metastatic thyroid cancer.

    Nggada, H A / Gali, B M / Khalil, M I A

    Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria

    2005  Volume 14, Issue 1, Page(s) 92–94

    Abstract: Background: The objective of this paper is to highlight the importance of tissue biopsy for histopathological diagnosis.: Method: A report of a 46-year-old farmer with post-thyroidectomy metastatic thyroid cancer.: Result: A post-thyroidectomy ... ...

    Abstract Background: The objective of this paper is to highlight the importance of tissue biopsy for histopathological diagnosis.
    Method: A report of a 46-year-old farmer with post-thyroidectomy metastatic thyroid cancer.
    Result: A post-thyroidectomy patient presenting with extensive skull and lumbar spine metastasis, paraparesis, huge occipital swelling and good healed scar without tumour residue. The thyroidectomy specimen was not subjected to histopathological diagnosis. Fine needle aspiration cytology of the occipital swelling revealed metastatic follicular carcinoma. Patient was placed on thyroxine 0.5mg daily with great improvement of lower limb muscle power.
    Conclusion: These bony metastases could have been reduced if proper investigation was done. There is need for continuous medical education for all clinical medical personnel.
    MeSH term(s) Adult ; Biopsy, Needle ; Bone Neoplasms/diagnosis ; Bone Neoplasms/secondary ; Bone Neoplasms/therapy ; Developing Countries ; Diagnosis, Differential ; Goiter, Nodular/pathology ; Goiter, Nodular/surgery ; Humans ; Immunohistochemistry ; Male ; Neoplasm Staging ; Nigeria ; Postoperative Complications ; Prognosis ; Risk Assessment ; Thyroid Neoplasms/pathology ; Thyroid Neoplasms/surgery ; Thyroidectomy/methods
    Language English
    Publishing date 2005-04-14
    Publishing country Nigeria
    Document type Case Reports ; Journal Article
    ISSN 1115-2613
    ISSN 1115-2613
    DOI 10.4314/njm.v14i1.37143
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  10. Article: The status of patients with negative appendicectomies in Maiduguri.

    Eni, U E / Nggada, H A / Gali, B M

    African journal of medicine and medical sciences

    2005  Volume 34, Issue 4, Page(s) 341–343

    Abstract: This study was conducted to verify the status of patients with negative appendicectomies in our practice and thus assess possible ways of reducing it. Of a total of 554 appendicectomies done in UMTH from January 1997 to December 2001, 27 (4.9 %) of these ...

    Abstract This study was conducted to verify the status of patients with negative appendicectomies in our practice and thus assess possible ways of reducing it. Of a total of 554 appendicectomies done in UMTH from January 1997 to December 2001, 27 (4.9 %) of these appendices were reported at histology as normal. 21 (77.8 %) were females and 6 (22.2 %) were males giving a female to male ratio of 3.5 to 1. The age range of the female patients was between 18 and 47 years with a mean 28.8 (SD) of (8.2) years. The age range of the male patients was between 11 and 47 years with a mean 31.5 (SD) of (12.6) years. The diagnostic alternatives depict the common scenario: Gynaecological conditions, urinary problems, peptic ulcer disease and non specific abdominal pain which are some of the major known differential diagnosis of acute appendicitis. Therefore careful clinical assessment of the patient should be depended upon for the diagnosis of appendicitis especially in our environment where sophisticated aids to diagnosis remains scarce.
    MeSH term(s) Adolescent ; Adult ; Appendectomy/utilization ; Appendicitis/diagnosis ; Appendicitis/surgery ; Child ; Diagnosis, Differential ; Diagnostic Errors ; Female ; Health Status ; Humans ; Male ; Medical Audit ; Middle Aged ; Nigeria
    Language English
    Publishing date 2005-12
    Publishing country Nigeria
    Document type Journal Article
    ZDB-ID 429127-x
    ISSN 0309-3913 ; 1116-4077
    ISSN 0309-3913 ; 1116-4077
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