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  1. Article ; Online: Impact of a structured reporting template on the quality of HRCT radiology reports for interstitial lung disease.

    Ngo, Han G / Nair, Girish B / Al-Katib, Sayf

    Clinical imaging

    2023  Volume 97, Page(s) 78–83

    Abstract: Purpose: This QI study compared the completeness of HRCT radiology reports before and after the implementation of a disease-specific structured reporting template for suspected cases of interstitial lung disease (ILD).: Materials and methods: A pre- ... ...

    Abstract Purpose: This QI study compared the completeness of HRCT radiology reports before and after the implementation of a disease-specific structured reporting template for suspected cases of interstitial lung disease (ILD).
    Materials and methods: A pre-post study of radiology reports for HRCT of the thorax at a multicenter health system was performed. Data was collected in 6-month period intervals before (June 2019-November 2019) and after (January 2021-June 2021) the implementation of a disease-specific template. The use of the template was voluntary. The primary outcome measure was the completeness of HRCT reports graded based on the documentation of ten descriptors. The secondary outcome measure assessed which descriptor(s) improved after the intervention.
    Results: 521 HRCT reports before and 557 HRCT reports after the intervention were reviewed. Of the 557 reports, 118 reports (21%) were created using the structured reporting template. The mean completeness score of the pre-intervention group was 9.20 (SD = 1.08) and the post-intervention group was 9.36 (SD = 1.03) with a difference of -0.155, 95% CI [-0.2822, -0.0285, p < 0.0001]. Within the post-intervention group, the mean completeness score of the unstructured reports was 9.25 (SD = 1.07) and the template reports was 9.93 (SD = 0.25) with a difference of -0.677, 95% CI [-0.7871, -0.5671, p < 0.0001]. After the intervention, the use of two descriptors improved significantly: presence of honeycombing from 78.3% to 85.1% (p < 0.0039) and technique from 90% to 96.6% (p < 0.0001).
    Discussion: Shifting to disease-specific structured reporting for HRCT exams of suspected ILD is beneficial, as it improves the completeness of radiology reports. Further research on how to improve the voluntary uptake of a disease-specific template is needed to help increase the acceptance of structured reporting among radiologists.
    MeSH term(s) Research Report/standards ; Research Report/trends ; Radiology/methods ; Radiology/standards ; Radiology/trends ; Lung Diseases, Interstitial/diagnostic imaging ; Radiography, Thoracic/methods ; Radiography, Thoracic/standards ; Humans
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2023.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Persistent Orthostatic Hypotension in a Patient With Acromegaly: Resolution With Transsphenoidal Hypophysectomy.

    Kneen, Kassy E / Ngo, Han G / Ghimire, Bipin / Banka, Ajaz A

    Cureus

    2022  Volume 14, Issue 4, Page(s) e24436

    Abstract: Acromegaly is a rare condition characterized by excessive secretion of growth hormone from a pituitary tumor. It can affect multiple systems and can be fatal with cardiac dysfunction being the most common cause of death in these patients. Autonomic ... ...

    Abstract Acromegaly is a rare condition characterized by excessive secretion of growth hormone from a pituitary tumor. It can affect multiple systems and can be fatal with cardiac dysfunction being the most common cause of death in these patients. Autonomic dysfunction is a less studied subject in patients with acromegaly, and the exact pathophysiology is still unclear. Here we present a case of a patient with persistent orthostatic hypotension, who was found to have acromegaly and pituitary adenoma upon further evaluation. Her orthostatic symptoms failed to improve with conservative measures and medical management, but unexpectedly resolved after transsphenoidal hypophysectomy was performed.
    Language English
    Publishing date 2022-04-24
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.24436
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Six logical steps that connect the introduction of the Nernst equation to its clinical application.

    Ngo, Han G / Dandu, Chaitu / Gibney, Brianna L / Kuang, Serena Y

    Advances in physiology education

    2022  Volume 46, Issue 4, Page(s) 540–543

    Abstract: The Nernst equation is key to understanding the electrophysiology of the cell membrane and the pathophysiology of ... ...

    Abstract The Nernst equation is key to understanding the electrophysiology of the cell membrane and the pathophysiology of K
    MeSH term(s) Humans ; Hyperkalemia/diagnosis ; Hypokalemia ; Learning ; Students, Medical
    Language English
    Publishing date 2022-07-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1024917-5
    ISSN 1522-1229 ; 1043-4046
    ISSN (online) 1522-1229
    ISSN 1043-4046
    DOI 10.1152/advan.00096.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Cellular Self-Digestion and Persistence in Bacteria.

    Mohiuddin, Sayed Golam / Ghosh, Sreyashi / Ngo, Han G / Sensenbach, Shayne / Karki, Prashant / Dewangan, Narendra K / Angardi, Vahideh / Orman, Mehmet A

    Microorganisms

    2021  Volume 9, Issue 11

    Abstract: Cellular self-digestion is an evolutionarily conserved process occurring in prokaryotic cells that enables survival under stressful conditions by recycling essential energy molecules. Self-digestion, which is triggered by extracellular stress conditions, ...

    Abstract Cellular self-digestion is an evolutionarily conserved process occurring in prokaryotic cells that enables survival under stressful conditions by recycling essential energy molecules. Self-digestion, which is triggered by extracellular stress conditions, such as nutrient depletion and overpopulation, induces degradation of intracellular components. This self-inflicted damage renders the bacterium less fit to produce building blocks and resume growth upon exposure to fresh nutrients. However, self-digestion may also provide temporary protection from antibiotics until the self-digestion-mediated damage is repaired. In fact, many persistence mechanisms identified to date may be directly or indirectly related to self-digestion, as these processes are also mediated by many degradative enzymes, including proteases and ribonucleases (RNases). In this review article, we will discuss the potential roles of self-digestion in bacterial persistence.
    Language English
    Publishing date 2021-10-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9112269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Cellular Self-Digestion and Persistence in Bacteria

    Mohiuddin, Sayed Golam / Ghosh, Sreyashi / Ngo, Han G. / Sensenbach, Shayne / Karki, Prashant / Dewangan, Narendra K. / Angardi, Vahideh / Orman, Mehmet A.

    Microorganisms. 2021 Oct. 31, v. 9, no. 11

    2021  

    Abstract: Cellular self-digestion is an evolutionarily conserved process occurring in prokaryotic cells that enables survival under stressful conditions by recycling essential energy molecules. Self-digestion, which is triggered by extracellular stress conditions, ...

    Abstract Cellular self-digestion is an evolutionarily conserved process occurring in prokaryotic cells that enables survival under stressful conditions by recycling essential energy molecules. Self-digestion, which is triggered by extracellular stress conditions, such as nutrient depletion and overpopulation, induces degradation of intracellular components. This self-inflicted damage renders the bacterium less fit to produce building blocks and resume growth upon exposure to fresh nutrients. However, self-digestion may also provide temporary protection from antibiotics until the self-digestion-mediated damage is repaired. In fact, many persistence mechanisms identified to date may be directly or indirectly related to self-digestion, as these processes are also mediated by many degradative enzymes, including proteases and ribonucleases (RNases). In this review article, we will discuss the potential roles of self-digestion in bacterial persistence.
    Keywords bacteria ; energy ; population growth ; proteinases ; ribonucleases
    Language English
    Dates of publication 2021-1031
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9112269
    Database NAL-Catalogue (AGRICOLA)

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