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Article ; Online: Unmasking the triad of burnout, absenteeism, and poor sleep among healthcare workers during the third wave of COVID-19 pandemics. Results from the national AMADEUS study.

Fond, Guillaume / Smith, Lee / Tran, Bach / Lucas, Guillaume / Nguyen, Tham Thi / Yon, Dong Keon / Boyer, Laurent

2024 Volume 355, Page(s) 247–253

Abstract: Background: Burnout and absenteeism are prevalent among healthcare workers, reflecting prolonged work-related stress and dissatisfaction with their job. Identifying poor sleep as a contributing factor can assist in developing targeted interventions. ... ...

Abstract	Background: Burnout and absenteeism are prevalent among healthcare workers, reflecting prolonged work-related stress and dissatisfaction with their job. Identifying poor sleep as a contributing factor can assist in developing targeted interventions. This study explored the relationship between burnout, absenteeism, and sleep among healthcare workers. Methods: A nationwide online cross-sectional study was conducted among healthcare professionals in France during the third wave of COVID-19, from May 2021 to June 2021. Recruitment strategies included outreach through social and professional networks and email invitations. Burnout was assessed using the Maslach Burnout Inventory, absenteeism through self-reported days absent in the preceding 12 months, and sleep quality using the Pittsburgh Sleep Quality Index. The association between burnout, absenteeism, and poor sleep was analyzed using multivariate logistic regression, accounting for individual and professional variables. The study also explored various sleep dimension abnormalities. Results: Of 10,087 healthcare workers, 55.2 % reported burnout, 20.5 % absenteeism, and 64.8 % poor sleep. Burnout and absenteeism were more frequent in individuals with poor sleep compared to those with good sleep (74.2 % vs. 25.8 % and 75.6 % vs. 24.4 %, respectively). The multivariate analyses confirmed the associations between burnout, absenteeism, and poor sleep (Adjusted Odds Ratio [aOR] = 2.15, 95 % CI [1.97-2.35], p < 0.001; and aOR = 1.49, 95 % CI [1.32-1.67], p < 0.001, respectively). Interpretation: The study highlighted the intricate relationship between burnout, absenteeism, and poor sleep among healthcare professionals, informing workforce management and policy decisions to foster a supportive work environment and enhance their well-being.
MeSH term(s)	Humans ; Absenteeism ; Cross-Sectional Studies ; Pandemics ; COVID-19/epidemiology ; Health Personnel ; Burnout, Professional/epidemiology ; Burnout, Psychological ; Sleep Initiation and Maintenance Disorders/epidemiology ; Sleep ; Psychological Tests ; Self Report
Language	English
Publishing date	2024-03-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	135449-8
ISSN	1573-2517 ; 0165-0327
ISSN (online)	1573-2517
ISSN	0165-0327
DOI	10.1016/j.jad.2024.03.157
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Article: Characterizing the Development of Research Landscapes in Substance Use and HIV/AIDS During 1990 to 2021.

Nguyen, Tham Thi / Nguyen, Hien Thu / Do, Huyen Phuc / Ho, Cyrus Sh / Ho, Roger Cm

Substance abuse : research and treatment

2023 Volume 17, Page(s) 11782218231177515

Abstract: Mitigating the impacts of Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) and substance use requires comprehensive and systematic thinking in designing interventions and developing policies. This study describes the growth of ... ...

Abstract	Mitigating the impacts of Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) and substance use requires comprehensive and systematic thinking in designing interventions and developing policies. This study describes the growth of research publications from 1991 to 2021 in the Web of Science database and points out current research landscapes in the fields of HIV/AIDS and substance use. Latent Dirichlet Allocation was used for classifying 21 359 papers into corresponding topics. The most common topics were HIV transmission, HIV infection, quality of life and mental health of substance users, and the biomedical effect of substance use. Emerging research landscapes include vulnerabilities of people who inject drugs to HIV transmission and related health problems. This study found a lack of research on health services, interdisciplinary and inter-sectoral in combination with clinical evaluation and treatment services. Future investment and implementation of HIV/AIDS and substance use programs should focus on research of health services and clinical evaluation, especially context-specific interventions.
Language	English
Publishing date	2023-06-05
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1458030-5
ISSN	1547-0164 ; 1178-2218 ; 0889-7077
ISSN (online)	1547-0164
ISSN	1178-2218 ; 0889-7077
DOI	10.1177/11782218231177515
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Article: Isolation and characterization of

Nguyen, Tham Thi / Vu-Khac, Hung / Nguyen, Tan Duc

Veterinary world

2020 Volume 13, Issue 8, Page(s) 1679–1684

Abstract: Background and aim: Clostridium perfringens: Materials and methods: The prevalence of : Results: A total of 116 : Conclusion: Type A is the most prevalent ... ...

Abstract	Background and aim: Clostridium perfringens Materials and methods: The prevalence of Results: A total of 116 Conclusion: Type A is the most prevalent among
Language	English
Publishing date	2020-08-25
Publishing country	India
Document type	Journal Article
ZDB-ID	2456277-4
ISSN	2231-0916 ; 0972-8988
ISSN (online)	2231-0916
ISSN	0972-8988
DOI	10.14202/vetworld.2020.1679-1684
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Article: Association between physical activity and health in healthcare professionals : Results from the nationwide AMADEUS survey.

Fond, Guillaume / Smith, Lee / Boussat, Bastien / Lucas, Guillaume / Yon, Dong Keon / Tran, Bach / Nguyen, Tham Thi / Stubbs, Brendon / Boyer, Laurent

Revue d'epidemiologie et de sante publique

2023 Volume 71, Issue 6, Page(s) 102183

Abstract: Objective: The objective of this study was to assess the prevalence of healthcare professionals engaging in insufficient levels of physical activity (PA) and to identify sociodemographic, professional and health characteristics associated with ... ...

Abstract	Objective: The objective of this study was to assess the prevalence of healthcare professionals engaging in insufficient levels of physical activity (PA) and to identify sociodemographic, professional and health characteristics associated with insufficient PA levels. Methods: We conducted a nationwide online cross-sectional study targeting healthcare professionals in France from May 2021 to June 2021. Participant recruitment involved outreach through social networks, professional networks, and email invitations. PA levels were assessed using the International Physical Activity Questionnaire (IPAQ), with insufficient PA defined as weekly PA totaling less than 600 mets/week. Results: The study included a total of 10,325 participants, of whom 3939 (38.1%, 95% confidence interval 37.1-39.0%) exhibited insufficient levels of PA. In the multivariable analysis, we identified factors associated with insufficient PA: ages between 35-44 (aOR=1.58, 95%CI [1.21-2.06], p=.001) and 45-54 years (aOR=1.40, 95%CI [1.07-1.83], p =.015), gender (female aOR=1.47, 95%CI [1.12-1.44], p<.001), and professions including health executive (aOR=1.27, 95%CI [1.32-1.64], p<.001), nurse assistant (aOR=1.25, 95%CI [1.07-1.47], p=.006), and physician (aOR=1.18, 95%CI [1.03-1.34], p=.015). Additionally, burnout (aOR=1.32, 95%CI [1.21-1.44], p<.001), tobacco use (aOR=1.33, 95%CI [1.20-1.58], p<.001), being overweight (aOR=1.39, 95%CI [1.28-1.52], p<.001), major depression (aOR=1.44, 95%CI [1.20-1.47], p<.001), and sleep disorders (aOR=1.14, 95%CI [1.05-1.25], p=.002) were associated with insufficient PA. Work night shifts was associated with sufficient PA. Conclusion: Our study has revealed a substantial prevalence of healthcare professionals with insufficient PA levels. This prevalence, coupled with various associated health-damaging behaviors and mental health issues, underscores the importance of acknowledging the barriers they encounter in adopting a physically active lifestyle.
MeSH term(s)	Adult ; Female ; Humans ; Cross-Sectional Studies ; Delivery of Health Care ; Exercise ; Health Behavior ; Surveys and Questionnaires ; Health Personnel ; Mental Health
Language	English
Publishing date	2023-11-07
Publishing country	France
Document type	Journal Article
ZDB-ID	199128-0
ISSN	0398-7620
ISSN	0398-7620
DOI	10.1016/j.respe.2023.102183
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Article ; Online: Preparation and characterization of spiked gold nanobipyramids and its antibacterial effect on methicillin-resistant Staphylococcus aureus and methicillin-sensitive Staphylococcus aureus.

Huynh, Phat Trong / Le Tran, Khanh Thi / Nguyen, Tham Thi Hong / Lam, Vinh Quang / Phan, Ngan Thi Kim / Ngo, Thanh Vo Ke

Journal, genetic engineering & biotechnology

2023 Volume 21, Issue 1, Page(s) 121

Abstract: Background: This paper reports the preparation of a new family of spiked gold nanoparticles, spiked gold nanobipyramids (SNBPs). This protocol includes the process to synthesize gold nanobipyramids (NBPs) using combined seed-mediated and microwave- ... ...

Abstract	Background: This paper reports the preparation of a new family of spiked gold nanoparticles, spiked gold nanobipyramids (SNBPs). This protocol includes the process to synthesize gold nanobipyramids (NBPs) using combined seed-mediated and microwave-assisted method and procedure to form spikes on whole surface of gold nanobipyramid. We also evaluated the antibacterial activity against both methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) in various concentrations of SNBPs and NBPs by well diffusion assay, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) determination. The effect of SNBPs on exposed bacteria was observed by scanning electron microscopy. Results: The UV-Vis of purified NBPs exhibited two absorption bands located at 550 nm and 849 nm with yield of bipyramidal particles more than 90%. The average size of NBPs was 76.33 ± 10.11 nm in length and 26.57 ± 2.25 nm in diameter, respectively, while SNBPs were prolongated in length and achieved 182.37 ± 21.74 nm with multi-branches protruding whole surface areas. In antibacterial evaluations, SNBPs and NBPs showed antibacterial activity with MIC of 6.25 μl/ml and 12.5 μl/ml, respectively, for MSSA while 12.5 μl/ml and 25 μl/ml, respectively, for MRSA. Besides, MBC values of SNBPs and NBPs were found to be 12.5 μl/ml and 25 μl/ml, respectively, against MSSA while 25 μl/ml and 50 μl/ml, respectively, against MRSA. Furthermore, scanning electron microscopy observation showed the mechanism that SNBPs damaged the outer membrane, released cytoplasm, and altered the normal morphology of MRSA and MSSA, leading to bacterial death. Conclusions: This report suggests that these SNBPs are potential antibacterial agents that can be applied as antibacterial materials to inhibit the growth of human bacterial pathogen infections related to antibiotic-resistant bacteria.
Language	English
Publishing date	2023-11-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2637420-1
ISSN	2090-5920 ; 1687-157X ; 2090-5920
ISSN (online)	2090-5920
ISSN	1687-157X ; 2090-5920
DOI	10.1186/s43141-023-00589-4
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Article: Preferences for childbirth delivery and pain relief methods among pregnant women in Vietnam.

Nguyen, Tham Thi / Nguyen, Long Hoang / Nguyen, Ha Thu Thi / Dam, Vu Anh Trong / Vu, Thuc Minh Thi / Latkin, Carl A / Zhang, Melvyn W B / Ho, Roger C M / Ho, Cyrus S H

Frontiers in medicine

2024 Volume 11, Page(s) 1290232

Abstract: Background: Understanding childbirth delivery and pain relief method preferences is important as a part of the shared decision-making process between pregnant women and health professionals. This study aimed to examine the preferences for childbirth ... ...

Abstract	Background: Understanding childbirth delivery and pain relief method preferences is important as a part of the shared decision-making process between pregnant women and health professionals. This study aimed to examine the preferences for childbirth delivery modes and pain relief methods and factors related to these preferences among pregnant women in Vietnam. Methods: A cross-sectional survey on pregnant women was conducted in two obstetrics hospitals in Vietnam. Face-to-face interviews using a structured questionnaire were performed to collect information about sociodemographic characteristics, pregnancy characteristics, preferences for different childbirth delivery modes, and pain relief methods. Multivariate logistic regression was employed for determining associated factors with the preferences. Results: Of 576 pregnant women, 34% of participants preferred cesarean section. Most of the sample did not have any preferences for specific pharmacological pain relief methods (70.1%), while support from partner/relatives was the most preferable non-pharmacological method (61.3%), following by water birth (11.1%) and acupuncture (9.9%). Desire to have another baby, relatives' experience, selection date of birth, and instrumental social support were major drivers of the cesarean section selection. This preference was an important factor in the preference for pharmacological pain relief. Meanwhile, high levels of informational and emotional support were associated with non-pharmacological method preference. Conclusion: This study highlighted a high preference rate for cesarean section in urban pregnant women in Vietnam. Holistic approaches from family, health facility, and policy should be performed to diminish the cesarean rate preference and promote the use of non-pharmacological pain relief methods during birth.
Language	English
Publishing date	2024-01-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2024.1290232
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Article ; Online: Promising clinical and immunological efficacy of Bacillus clausii spore probiotics for supportive treatment of persistent diarrhea in children.

Dang, Ha Thuy / Tran, Dien Minh / Phung, Thuy Thi Bich / Bui, Anh Thi Phuong / Vu, Yen Hai / Luong, Minh Thi / Nguyen, Hang Minh / Trinh, Huong Thi / Nguyen, Tham Thi / Nguyen, Anh Hoa / Van Nguyen, Anh Thi

Scientific reports

2024 Volume 14, Issue 1, Page(s) 6422

Abstract: Persistent diarrhea is a severe gastroenteric disease with relatively high risk of pediatric mortality in developing countries. We conducted a randomized, double-blind, controlled clinical trial to evaluate the efficacy of liquid-form Bacillus clausii ... ...

Abstract	Persistent diarrhea is a severe gastroenteric disease with relatively high risk of pediatric mortality in developing countries. We conducted a randomized, double-blind, controlled clinical trial to evaluate the efficacy of liquid-form Bacillus clausii spore probiotics (LiveSpo CLAUSY; 2 billion CFU/5 mL ampoule) at high dosages of 4-6 ampoules a day in supporting treatment of children with persistent diarrhea. Our findings showed that B. clausii spores significantly improved treatment outcomes, resulting in a 2-day shorter recovery period (p < 0.05) and a 1.5-1.6 folds greater efficacy in reducing diarrhea symptoms, such as high frequency of bowel movement of ≥ 3 stools a day, presence of fecal mucus, and diapered infant stool scale types 4-5B. LiveSpo CLAUSY supportive treatment achieved 3 days (p < 0.0001) faster recovery from diarrhea disease, with 1.6-fold improved treatment efficacy. At day 5 of treatment, a significant decrease in blood levels of pro-inflammatory cytokines TNF-α, IL-17, and IL-23 by 3.24% (p = 0.0409), 29.76% (p = 0.0001), and 10.87% (p = 0.0036), respectively, was observed in the Clausy group. Simultaneously, there was a significant 37.97% decrease (p = 0.0326) in the excreted IgA in stool at day 5 in the Clausy group. Overall, the clinical study demonstrates the efficacy of B. clausii spores (LiveSpo CLAUSY) as an effective symptomatic treatment and immunomodulatory agent for persistent diarrhea in children.Trial registration: NCT05812820.
MeSH term(s)	Infant ; Humans ; Child ; Bacillus clausii ; Spores, Bacterial ; Diarrhea/therapy ; Cytokines ; Probiotics/therapeutic use
Chemical Substances	Cytokines
Language	English
Publishing date	2024-03-18
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-56627-9
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Article ; Online: Avoidance of healthcare service use and correlates among HIV-positive patients in Vietnam: a cross-sectional study.

Nguyen, Huong Lan Thi / Bui, Thu Minh / Dam, Vu Anh Trong / Nguyen, Tham Thi / Nguyen, Hien Thu / Zeng, Ga Mei / Bradley, Don / Nguyen, Quang N / Ngo, Toan Van / Latkin, Carl A / Ho, Roger Cm / Ho, Cyrus Sh

BMJ open

2023 Volume 13, Issue 12, Page(s) e074005

Abstract: Objective: The prevention of HIV/AIDS is not making sufficient progress. The slow reduction of HIV/AIDS infections needs to prioritise hesitancy towards service utilisation, including treatment duration, social support and social stigma. This study ... ...

Abstract	Objective: The prevention of HIV/AIDS is not making sufficient progress. The slow reduction of HIV/AIDS infections needs to prioritise hesitancy towards service utilisation, including treatment duration, social support and social stigma. This study investigates HIV-positive patients' avoidance of healthcare services and its correlates. Design: A cross-sectional study. Setting: The secondary data analysis used cross-sectional data from a randomised controlled intervention, examining the effectiveness of HIV-assisted smartphone applications in the treatment of HIV/AIDS patients in the Bach Mai and Ha Dong clinics in Hanoi. Methods: Simple random sampling was used to identify 495 eligible patients. Two-tailed χ Primary and secondary outcome measures: The main study outcome was the patients' healthcare avoidance and frequency of healthcare avoidance. The association of individual characteristics, social and behavioural determinants of HIV patients' usage of health services was also determined based on the collected data using structured questionnaires. Results: Nearly half of the participants avoid health service use (47.3%), while 30.7% rarely avoid health service use. Duration of antiretroviral therapy and initial CD4 cell count were negatively associated with avoidance of health services and frequency of health service avoidance. Similarly, those with the middle and highest income were more likely to avoid health services compared with those with the lowest income. People having health problems avoided health service use more frequently (OR 1.47, 95% CI 1.35 to 1.61). Conclusions: Our study's findings identify characteristics of significance in relation to health service avoidance and utilisation among HIV-positive patients. The results highlighted the need to improve satisfaction, adherence and utilisation of treatment. Moreover, identifying ways to address or incorporate those social determinants in new policy may also help the treatment of HIV/AIDS and strategically allocate funding in the changing financial and political climate of Vietnam. Trial registration number: Thai Clinical Trials Registry TCTR20220928003.
MeSH term(s)	Humans ; HIV Infections/prevention & control ; Acquired Immunodeficiency Syndrome/drug therapy ; Cross-Sectional Studies ; Vietnam ; Surveys and Questionnaires ; Health Services ; Treatment Refusal
Language	English
Publishing date	2023-12-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-074005
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Article: A longitudinal assessment of appetite loss and nutritional care among postoperative patients in Vietnam.

Nguyen, Tu Huu / Ta, Nguyet Thi / Dang, Anh Kim / Nguyen, Tham Thi / Dam, Vu Anh Trong / Latkin, Carl A / Ho, Cyrus S H / Ho, Roger C M

Frontiers in nutrition

2023 Volume 10, Page(s) 1008636

Abstract: Background: Post-operative appetite loss is an important complication affecting surgical outcomes. It has been estimated that nearly 60% of patients having gastrointestinal or major elective surgeries suffer from malnutrition. Appetite refers to the ... ...

Abstract	Background: Post-operative appetite loss is an important complication affecting surgical outcomes. It has been estimated that nearly 60% of patients having gastrointestinal or major elective surgeries suffer from malnutrition. Appetite refers to the physical desire for food appetite, and losing appetite after surgery may result in a decrease in body weight, impairment of intestinal absorption and eventually, malnutrition among postoperative patients. This study aims to assess appetite status and other relevant factors among abdominal postoperative patients in Vietnam. Methods: A cross-sectional study was conducted on 169 abdominal postoperative patients from June 1st to August 30th, 2016 at Hanoi Medical University Hospital, Hanoi, Vietnam. Appetite score was computed by using the Council on Nutrition Appetite Questionnaire (CNAQ). This study used GEE to account for the potential correlation of outcomes of the longitudinal assessment, assuming an independent correlation structure. Results: The primary and secondary outcome measures: highest average appetite score was recorded in the preoperative day and the score declined throughout seven-day duration. Patients who were female, under general anesthetics and being under open surgery tended to get lower appetite scores. The majority of patients had moderate to good appetite in both the preoperative day and seven days post-operation. Conclusion: Women should receive more care and help in regaining their appetite after surgery. Treatment for appetite loss through non-pharmaceutical measures should be prioritized. Interventions that increase the appetite of patients after abdominal surgery should be targeted on patients being under general anesthetic as well as open surgery and be undertaken with caution.
Language	English
Publishing date	2023-03-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2023.1008636
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Article: Scholarly literature in HIV-related lesbian, gay, bisexual, and transgender studies: A bibliometric analysis.

Nguyen, Tham Thi / Do, Anh Linh / Nguyen, Long Hoang / Vu, Giang Thu / Dam, Vu Anh Trong / Latkin, Carl A / Hall, Brian J / Ho, Cyrus S H / Zhang, Melvyn W B / Ho, Roger C M

Frontiers in psychology

2023 Volume 14, Page(s) 1028771

Abstract: Introduction: Lesbian, gay, bisexual, and transgendered (LGBT) people are marginalized and understudied. Analyzing research activity worldwide is vital to better understand their needs in confronting the HIV epidemic. This study aimed to evaluate the ... ...

Abstract	Introduction: Lesbian, gay, bisexual, and transgendered (LGBT) people are marginalized and understudied. Analyzing research activity worldwide is vital to better understand their needs in confronting the HIV epidemic. This study aimed to evaluate the global literature to identify the research collaboration, content, and tendency in HIV-related issues among the LGBT populations. Methods: Peer-reviewed original articles and reviews were achieved from the Web of Science Core Collection database. Country's collaborations and co-occurrence of most frequent terms were illustrated by VOSviewer software. The Latent Dirichlet Allocation (LDA) and the linear regression model were utilized to uncover the hidden topics and examine the research trend. Results: From 1990 to 2019, a total of 13,096 publications were found. Stigma, sexual risk behaviors and HIV testing were the major topics in the LGBT research during the study period. Among 15 topics, topics about HIV/Sexually transmitted infections (STIs) prevalence, Outcomes of HIV/AIDS care and treatment, and Opportunistic infections in HIV-positive LGBT people showed decreasing attention over years, while other topics had a slight to moderate increase. Discussion: Our study underlined the exponential growth of publications on the LGBT population in HIV research, and suggested the importance of performing regional collaborations in improving research capacity. Moreover, further research should focus on examining the manner to increase the coverage of HIV testing and treatment, as well as implement HIV-interventions with low cost and easy to scale-up.
Language	English
Publishing date	2023-02-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2023.1028771
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