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Article ; Online: Transition of dominant canine parvovirus genotype from 2b to 2c in Vietnamese dogs.

Nguyen Van, Dung / Le, Thanh Dinh Ha / Maeda, Ken

2022 Volume 58, Issue 2

Abstract: Canine parvovirus (CPV) is one of the most important pathogens causing enteritis in dogs. Although there have been a few reports of CPV in Vietnam, recent information on CPV infection in domestic dogs in Vietnam is limited. Faecal samples collected from ... ...

Abstract	Canine parvovirus (CPV) is one of the most important pathogens causing enteritis in dogs. Although there have been a few reports of CPV in Vietnam, recent information on CPV infection in domestic dogs in Vietnam is limited. Faecal samples collected from 30 diarrheic and 50 healthy dogs were examined by PCR for detection of CPV DNA. The prevalence of CPV in diarrheic dogs (43.3%, 13/30) was significantly higher than in healthy dogs (4.0%, 2/50), indicating that CPV was a major cause of diarrhoea in domestic dogs. Genotyping of 15 CPV strains showed that both CPV‑2a and CPV‑2c were circulating and that CPV‑2c was a dominant CPV variant in Vietnam. Virus isolation was performed from faecal samples using A72/cSLAM cells, and nine CPV strains were successfully isolated. The dominant genotype spreading among Vietnamese dogs has changed from CPV‑2b to CPV‑2c.
MeSH term(s)	Animals ; Dogs ; Humans ; Dog Diseases/epidemiology ; Enteritis/veterinary ; Genotype ; Parvoviridae Infections/epidemiology ; Parvoviridae Infections/veterinary ; Parvovirus, Canine/genetics ; Phylogeny ; Vietnam/epidemiology
Language	English
Publishing date	2022-12-30
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2536397-9
ISSN	1828-1427 ; 0505-401X
ISSN (online)	1828-1427
ISSN	0505-401X
DOI	10.12834/VetIt.2237.13437.2
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Article ; Online: Molecular characterisation of the current high prevalence of the new CPV-2c variants in the Southern Vietnamese dogs signifies a widespread in the worldwide dog population.

Bui, Thi To Nga / Hoang, Minh / Nguyen, Van Dung / Nam Nguyen, Minh / Than, Van Thai

Veterinary medicine and science

2023 Volume 9, Issue 4, Page(s) 1553–1563

Abstract: Background: Canine parvovirus type 2 (CPV-2) is known as the primary etiological agent cause of acute gastroenteritis, myocarditis and death of canids worldwide. In Vietnam, although CPV-2 infection and its outbreaks are the most important risk factors ... ...

Abstract	Background: Canine parvovirus type 2 (CPV-2) is known as the primary etiological agent cause of acute gastroenteritis, myocarditis and death of canids worldwide. In Vietnam, although CPV-2 infection and its outbreaks are the most important risk factors of the canine's health concern, lack of available information about the molecular epidemiology of the CPV-2. Objectives: In this study, the complete coding sequences of 10 CPV-2 strains collected from dogs vaccinated with CPV-2 vaccination were analysed to better understand the genomic characteristics of the current circulating CPV-2 in Vietnam. Methods: Ten CPV-specific PCR-positive rectal swab samples were collected from dogs with acute symptoms of haemorrhagic diarrhoea and vomiting in Vietnam in 2019. The complete coding sequences of these CPV strains were analysed to determine their phylogeny and genetic relationship with other available CPV strains globally. Results: Analysis of the VP2 gene sequences demonstrated that the studied strains belonged to the new CPV-2c variants with the unique mutations at amino acids 5 Conclusions: This study provides deep insights into the molecular characteristics, genetic diversity, and evolution of circulating CPV-2 strains in Vietnam. We recommend more studies to estimate the effectiveness of the CPV vaccine and the need to continue developing other effective vaccination essential to better control the widespread of these new CPV-2 variants.
MeSH term(s)	Animals ; Dogs ; Capsid Proteins/chemistry ; Capsid Proteins/genetics ; Dog Diseases/epidemiology ; Dog Diseases/genetics ; Dog Diseases/prevention & control ; Parvoviridae Infections/epidemiology ; Parvoviridae Infections/genetics ; Parvoviridae Infections/prevention & control ; Parvoviridae Infections/veterinary ; Parvovirus, Canine/genetics ; Phylogeny ; Prevalence ; Vietnam/epidemiology ; Viral Vaccines/therapeutic use
Chemical Substances	Capsid Proteins ; Viral Vaccines
Language	English
Publishing date	2023-05-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.1163
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Book ; Online: A quantum annealing-sequential quadratic programming assisted finite element simulation for non-linear and history-dependent mechanical problems

Nguyen, Van-Dung / Wu, Ling / Remacle, Françoise / Noels, Ludovic

2023

Abstract: We propose a framework to solve non-linear and history-dependent mechanical problems based on a hybrid classical computer -- quantum annealer approach. Quantum Computers are anticipated to solve particular operations exponentially faster. The available ... ...

Abstract	We propose a framework to solve non-linear and history-dependent mechanical problems based on a hybrid classical computer -- quantum annealer approach. Quantum Computers are anticipated to solve particular operations exponentially faster. The available possible operations are however not as versatile as with a classical computer. However, quantum annealers (QAs) are well suited to evaluate the minimum state of a Hamiltonian quadratic potential. Therefore, we reformulate the elasto-plastic finite element problem as a double-minimisation process framed at the structural scale using the variational updates formulation. In order to comply with the expected quadratic nature of the Hamiltonian, the resulting non-linear minimisation problems are iteratively solved with the suggested Quantum Annealing-assisted Sequential Quadratic Programming (QA-SQP): a sequence of minimising quadratic problems is performed by approximating the objective function by a quadratic Taylor's series. Each quadratic minimisation problem of continuous variables is then transformed into a binary quadratic problem. This binary quadratic minimisation problem can be solved on quantum annealing hardware such as the D-Wave system. The applicability of the proposed framework is demonstrated with one- and two-dimensional elasto-plastic numerical benchmarks. The current work provides a pathway of performing general non-linear finite element simulations assisted by quantum computing. Comment: This is an updated version following reviewing process. The code and raw/processed data required to reproduce these findings is available on http://dx.doi.org/10.5281/zenodo.10451584 under the Creative Commons Attribution 4.0 International (CC BY 4.0) licence
Keywords	Computer Science - Computational Engineering ; Finance ; and Science
Subject code	531
Publishing date	2023-10-10
Publishing country	us
Document type	Book ; Online
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Article ; Online: Efficient Solution for Large-Scale IoT Applications with Proactive Edge-Cloud Publish/Subscribe Brokers Clustering.

Pham, Van-Nam / Lee, Ga-Won / Nguyen, VanDung / Huh, Eui-Nam

Sensors (Basel, Switzerland)

2021 Volume 21, Issue 24

Abstract: Large-scale IoT applications with dozens of thousands of geo-distributed IoT devices creating enormous volumes of data pose a big challenge for designing communication systems that provide data delivery with low latency and high scalability. In this ... ...

Abstract	Large-scale IoT applications with dozens of thousands of geo-distributed IoT devices creating enormous volumes of data pose a big challenge for designing communication systems that provide data delivery with low latency and high scalability. In this paper, we investigate a hierarchical Edge-Cloud publish/subscribe brokers model using an efficient two-tier routing scheme to alleviate these issues when transmitting event notifications in wide-scale IoT systems. In this model, IoT devices take advantage of proximate edge brokers strategically deployed in edge networks for data delivery services in order to reduce latency. To deliver data more efficiently, we propose a proactive mechanism that applies collaborative filtering techniques to efficiently cluster edge brokers with geographic proximity that publish and/or subscribe to similar topics. This allows brokers in the same cluster to exchange data directly with each other to further reduce data delivery latency. In addition, we devise a coordinative scheme to help brokers discover and bridge similar topic channels in the whole system, informing other brokers for data delivery in an efficient manner. Extensive simulation results prove that our model can adeptly support event notifications in terms of low latency, small amounts of relay traffic, and high scalability for large-scale, delay-sensitive IoT applications. Specifically, in comparison with other similar Edge-Cloud approaches, our proposal achieves the best in terms of relay traffic among brokers, about 7.77% on average. In addition, our model's average delivery latency is approximately 66% of PubSubCoord-alike's one.
Language	English
Publishing date	2021-12-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s21248232
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Article ; Online: Radiological risk assessment of outdoor

Hoang, Van-Hiep / Tai Tue, Nguyen / Nguyen, Thai-Son / Dang Quy, Tran / Nguyen, Thanh-Duong / Nguyen, Van-Dung

Journal of radiological protection : official journal of the Society for Radiological Protection

2023 Volume 43, Issue 2

Abstract: ... The ... ...

Abstract	The outdoor
MeSH term(s)	Radon/analysis ; Uranium/analysis ; Vietnam ; Mining ; Risk Assessment ; Radiation Monitoring
Chemical Substances	Radon (Q74S4N8N1G) ; Uranium (4OC371KSTK)
Language	English
Publishing date	2023-06-08
Publishing country	England
Document type	Journal Article
ZDB-ID	639411-5
ISSN	1361-6498 ; 0952-4746
ISSN (online)	1361-6498
ISSN	0952-4746
DOI	10.1088/1361-6498/acda43
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Article ; Online: Adaptive response of

Huynh, Thuc Quyen / Tran, Nguyen Bao Vy / Pham, Thi Thuy Vy / Le, Vo Bao Tran / Truong, Thien Phu / Huynh, Van An / Tong, Thi Hang / Trinh, Thi Truc Ly / Nguyen, Van Dung / Pham, Le Nhat Minh / Nguyen, Thi Hiep / Lin, Qifeng / Lim, Teck Kwang / Lin, Qingsong / Nguyen, Thi Thu Hoai

Microbiology (Reading, England)

2024 Volume 170, Issue 3

Abstract: Understanding the evolution of antibiotic resistance is important for combating drug-resistant bacteria. In this work, we investigated the adaptive response ... ...

Abstract	Understanding the evolution of antibiotic resistance is important for combating drug-resistant bacteria. In this work, we investigated the adaptive response of
MeSH term(s)	Humans ; Ciprofloxacin/pharmacology ; Pseudomonas aeruginosa/genetics ; Chromatography, Liquid ; Proteomics ; Pyocyanine ; Tandem Mass Spectrometry ; Pseudomonas Infections ; Anti-Bacterial Agents/pharmacology
Chemical Substances	Ciprofloxacin (5E8K9I0O4U) ; Pyocyanine (9OQM399341) ; Anti-Bacterial Agents
Language	English
Publishing date	2024-04-03
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1180712-x
ISSN	1465-2080 ; 1350-0872
ISSN (online)	1465-2080
ISSN	1350-0872
DOI	10.1099/mic.0.001443
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Article ; Online: Sap from various palms as a renewable energy source for bioethanol production

Nguyen Van Dung / Harifara Rabemanolontsoa / Shiro Saka

Chemical Industry and Chemical Engineering Quarterly, Vol 22, Iss 4, Pp 355-

2016 Volume 373

Abstract: Sap is a watery fluid that transports plant photosynthetic products towards various tissues to support growth. Tapping palms for their sap is reported to have originated from India approximately 4,000 years ago. Palm sap is rich in sugars with some ... ...

Abstract	Sap is a watery fluid that transports plant photosynthetic products towards various tissues to support growth. Tapping palms for their sap is reported to have originated from India approximately 4,000 years ago. Palm sap is rich in sugars with some inorganics and nutrients, which are attractive components for bioethanol production. Based on advances and current knowledge on the availability, collection, yield, and exploitation of various palm saps, this article evaluates their potential and sustainability as feedstocks for bioethanol production.
Keywords	palm sap ; tapping ; sugar ; fermentation ; bioethanol ; sustainable ; Chemistry ; QD1-999 ; Science ; Q ; Chemical engineering ; TP155-156 ; Chemical industries ; HD9650-9663
Language	English
Publishing date	2016-01-01T00:00:00Z
Publisher	Association of the Chemical Engineers of Serbia
Document type	Article ; Online
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Article: African swine fever virus vaccine candidate ASFV‐G‐ΔI177L efficiently protects European and native pig breeds against circulating Vietnamese field strain

Tran, Xuan Hanh / Le, Thi Thu Phuong / Nguyen, Quang Huy / Do, Thanh Thuy / Nguyen, Van Dung / Gay, Cyril G. / Borca, Manuel V. / Gladue, Douglas P.

Transboundary and emerging diseases. 2022 July, v. 69, no. 4

2022

Abstract: The recent spread of African swine fever (ASF) in the People's Republic of China and neighbouring countries in Asia has had significant economic consequences with an estimated direct cost of $55–$130 billion. This pandemic, originally detected in ... ...

Abstract	The recent spread of African swine fever (ASF) in the People's Republic of China and neighbouring countries in Asia has had significant economic consequences with an estimated direct cost of $55–$130 billion. This pandemic, originally detected in Republic of Georgia in 2007, has devastated the swine industry in large geographical areas of Southeast Asia with 14 countries reporting ASF outbreaks since the first documented case was confirmed in the city of Shenyang, Liaoning Province, China, on 3 August 2018. In the absence of any available vaccines, the control of ASF relies on the detection and culling of infected animals. The United States Department of Agriculture recently developed a recombinant experimental vaccine candidate, ASFV‐G‐ΔI177L, by deleting the I177L gene from the genome of the highly virulent pandemic ASFV strain Georgia, which efficaciouly protects pigs from the parental virus. Here, the initial studies were extended demonstrating that ASFV‐G‐ΔI177L is able to protect pigs against the virulent ASFV isolate currently circulating and producing disease in Vietnam with similar efficacy as reported against the Georgia strain. Comparative studies performed using a large number of pigs of European and Vietnamese origin demonstrated that a minimum protective dose of 10² HAD₅₀ of ASFV‐G‐ΔI177L equally protects animals of both breeds. In concurrence with those results, the onset of immunity in these animal breed showed appearance of protection in approximately one‐third of the animals by the second week post vaccination, with full protection achieved by the fourth week post vaccination. Therefore, results presented here demonstrated that ASFV‐G‐ΔI177L is able to induce protection against virulent Vietnameese ASFV field strains and is effective in protecting local breeds of pigs as efficiently as previously shown for European cross‐bred pigs. To our knowledge, this is the first report showing the efficacy of a Georgia 2007 based vaccine candidate in Asian breed of pigs or challenged with an Asian ASFV strain.
Keywords	African swine fever ; African swine fever virus ; crossbreds ; genes ; immunity ; pandemic ; pork industry ; swine ; vaccination ; vaccines ; virulence ; viruses ; China ; Georgia ; Republic of Georgia ; Vietnam
Language	English
Dates of publication	2022-07
Size	p. e497-e504.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	2414822-2
ISSN	1865-1682 ; 1865-1674
ISSN (online)	1865-1682
ISSN	1865-1674
DOI	10.1111/tbed.14329
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Flexible computation offloading in a fuzzy-based mobile edge orchestrator for IoT applications.

Nguyen, VanDung / Khanh, Tran Trong / Nguyen, Tri D T / Hong, Choong Seon / Huh, Eui-Nam

Journal of cloud computing (Heidelberg, Germany)

2020 Volume 9, Issue 1, Page(s) 66

Abstract: In the Internet of Things (IoT) era, the capacity-limited Internet and uncontrollable service delays for various new applications, such as video streaming analysis and augmented reality, are challenges. Cloud computing systems, also known as a solution ... ...

Abstract	In the Internet of Things (IoT) era, the capacity-limited Internet and uncontrollable service delays for various new applications, such as video streaming analysis and augmented reality, are challenges. Cloud computing systems, also known as a solution that offloads energy-consuming computation of IoT applications to a cloud server, cannot meet the delay-sensitive and context-aware service requirements. To address this issue, an edge computing system provides timely and context-aware services by bringing the computations and storage closer to the user. The dynamic flow of requests that can be efficiently processed is a significant challenge for edge and cloud computing systems. To improve the performance of IoT systems, the mobile edge orchestrator (MEO), which is an application placement controller, was designed by integrating end mobile devices with edge and cloud computing systems. In this paper, we propose a flexible computation offloading method in a fuzzy-based MEO for IoT applications in order to improve the efficiency in computational resource management. Considering the network, computation resources, and task requirements, a fuzzy-based MEO allows edge workload orchestration actions to decide whether to offload a mobile user to local edge, neighboring edge, or cloud servers. Additionally, increasing packet sizes will affect the failed-task ratio when the number of mobile devices increases. To reduce failed tasks because of transmission collisions and to improve service times for time-critical tasks, we define a new input crisp value, and a new output decision for a fuzzy-based MEO. Using the EdgeCloudSim simulator, we evaluate our proposal with four benchmark algorithms in augmented reality, healthcare, compute-intensive, and infotainment applications. Simulation results show that our proposal provides better results in terms of WLAN delay, service times, the number of failed tasks, and VM utilization.
Language	English
Publishing date	2020-11-25
Document type	Journal Article
ZDB-ID	2682472-3
ISSN	2192-113X ; 2192-113X
ISSN (online)	2192-113X
ISSN	2192-113X
DOI	10.1186/s13677-020-00211-9
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Article: Proteomic analysis of ceftazidime and meropenem-exposed Pseudomonas aeruginosa ATCC 9027.

Ngo, Hong Loan / Huynh, Thuc Quyen / Tran, Nguyen Bao Vy / Nguyen, Ngoc Hoa Binh / Tong, Thi Hang / Trinh, Thi Truc Ly / Nguyen, Van Dung / Das, Prem Prakash / Lim, Teck Kwang / Lin, Qingsong / Nguyen, Thi Thu Hoai

Proteome science

2023 Volume 21, Issue 1, Page(s) 15

Abstract: Background: Pseudomonas aeruginosa is well known for its intrinsic ability to resist a wide range of antibiotics, thus complicates treatment. Thus, understanding the response of the pathogen to antibiotics is important for developing new therapies. In ... ...

Abstract	Background: Pseudomonas aeruginosa is well known for its intrinsic ability to resist a wide range of antibiotics, thus complicates treatment. Thus, understanding the response of the pathogen to antibiotics is important for developing new therapies. In this study, proteomic response of P. aeruginosa to the commonly used anti-pseudomonas antibiotics, ceftazidime (Caz) and meropenem (Mem) was investigated. Methods: P. aeruginosa ATCC 9027, an antibiotic-susceptible strain, was exposed to sub-MIC values of antibiotics either Caz or Mem for 14 days to obtain E1 strains and then cultured in antibiotic-free environments for 10 days to obtain E2 strains. Proteomes of the initial and E1, E2 strains were identified and comparatively analyzed using isobaric tags for relative and absolute quantitation (iTRAQ) in cooperation with nano LC-MS/MS. Noted up and down-regulated proteins were confirmed with quantitative reverse transcriptase PCR (qRT-PCR). Results: Overall, 1039 and 1041 proteins were identified in Caz and Mem-exposed strains, respectively. Upon antibiotic exposure, there were 7-10% up-regulated (Caz: 71, Mem: 85) and down-regulated (Caz: 106, Mem: 69) proteins (1.5-fold change cut-off). For both Caz and Mem, the DEPs were primarily the ones involved in metabolic process, membrane, virulence, protein synthesis, and antibiotic resistance in which proteins involved in antibiotics resistance tended to be up-regulated while proteins involved in protein synthesis and metabolic process were down-regulated. Noted proteins included beta-lactamase AmpC which was up-regulated and OprD which was down-regulated in both the antibiotic-exposed strains. Besides, biofilm formation related proteins TssC1 and Hcp1 in Caz- exposed strains and the membrane/ periplasmic proteins Azu and PagL in Mem-exposed strains were found significantly down-regulated. qRT-PCR results confirmed the expression change of AmpC, Hcp1 and OprD proteins. Conclusion: Exposure of Pseudomonas aeruginosa to sub-MIC values of Caz and Mem resulted in around 10% change in its proteome. Not only proteins with confirmed roles in antibiotic resistance mechanisms changed their expression but also virulence- associated proteins. Both Caz and Mem response involved up-regulation of AmpC and down-regulation of OprD. While TssC1 and Hcp1 were responsible for Caz response, Azu and PagL were more likely involved in Mem response.
Language	English
Publishing date	2023-09-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2141087-2
ISSN	1477-5956
ISSN	1477-5956
DOI	10.1186/s12953-023-00217-6
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