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  1. Article ; Online: Femoral Neck Fracture with Avascular Necrosis.

    Ballas, Elissa R / Nguyen, Vincent T / Wolin, Ely A

    Journal of nuclear medicine technology

    2022  Volume 51, Issue 1, Page(s) 78–79

    Abstract: Hip fractures are common in the aging population, with complications such as avascular necrosis. We describe a case of an 85-y-old woman with early avascular necrosis as a complication from femoral neck fracture discovered on routine bone densitometry ... ...

    Abstract Hip fractures are common in the aging population, with complications such as avascular necrosis. We describe a case of an 85-y-old woman with early avascular necrosis as a complication from femoral neck fracture discovered on routine bone densitometry screening.
    MeSH term(s) Female ; Humans ; Aged ; Femur Head Necrosis/diagnosis ; Femur Head Necrosis/epidemiology ; Femur Head Necrosis/etiology ; Risk Factors ; Femoral Neck Fractures/complications
    Language English
    Publishing date 2022-08-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 189163-7
    ISSN 1535-5675 ; 0091-4916
    ISSN (online) 1535-5675
    ISSN 0091-4916
    DOI 10.2967/jnmt.122.264354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: "Diffusion of innovations": a feasibility study on the pericapsular nerve group block in the emergency department for hip fractures.

    Ramachandran, Anirudh / Montenegro, Michelle / Singh, Maninder / Dixon, Trevor / Kayani, Waqas / Liang, Timothy / Yu, Nick / Reddy, Srinivas / Liveris, Anna / Manyapu, Mallika / McEwan, Alyssia A / Nguyen, Vincent T / Sonenthal, Nechama V / Corbo, Jill / Friedman, Benjamin W / Sperling, Jeremy / Jones, Michael P / Halperin, Michael

    Clinical and experimental emergency medicine

    2022  Volume 9, Issue 3, Page(s) 198–206

    Abstract: Objective: Hip fractures are associated with significant morbidity and mortality. Ultrasound-guided peripheral nerve blocks are a safe method to manage pain and decrease opioid usage. The pericapsular nerve group (PENG) block is a novel, potentially ... ...

    Abstract Objective: Hip fractures are associated with significant morbidity and mortality. Ultrasound-guided peripheral nerve blocks are a safe method to manage pain and decrease opioid usage. The pericapsular nerve group (PENG) block is a novel, potentially superior block because of its motor-sparing effects. Through training, simulation, and supervision, we aim to determine whether it is feasible to perform the PENG block in the emergency department.
    Methods: Phase 1 consisted of emergency physicians attending a workshop to demonstrate ultrasound proficiency, anatomical understanding, and procedural competency using a low-fidelity model. Phase 2 consisted of a prospective, observational, feasibility study of 10 patients with hip fractures. Pain scores, side effects, and opioid usage data were collected.
    Results: The median pain score at time 0 (time of block) was 9 (interquartile range [IQR], 6.5-9). The median pain score at 30 minutes was 4 (IQR, 2.0-6.8) and 3.5 (IQR, 1.0-4.8) at 4 hours. All 10 patients required narcotics prior to the initiation of the PENG block with a median dosage of 6.25 morphine milligram equivalents (MME; IQR, 4.25-7.38 MME). After the PENG block, only 30% of the patients required further narcotics with a median dosage of 0 MME (IQR, 0-0.6 MME) until operative fixation.
    Conclusion: In this feasibility study, PENG blocks were safely administered by trained emergency physicians under supervision. We demonstrated data suggesting a trend of pain relief and decreased opiate requirements, and further investigation is necessary to measure efficacy.
    Language English
    Publishing date 2022-09-20
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2383-4625
    ISSN 2383-4625
    DOI 10.15441/ceem.22.177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Phase transitions of n-hexadecane in nanoencapsulated binary solutions of n-hexadecane and 1-octanol.

    Tubbs, Kyle W / Nguyen, Vincent T / Adalsteinsson, Thorsteinn

    The journal of physical chemistry. B

    2012  Volume 116, Issue 13, Page(s) 3954–3960

    Abstract: Binary solutions of n-hexadecane and 1-octanol were encapsulated within poly(tert-butyl methacrylate) nanocapsules and the phase transition behavior of the n-hexadecane studied. A sigmoidal correlation was found between the binary composition of the ... ...

    Abstract Binary solutions of n-hexadecane and 1-octanol were encapsulated within poly(tert-butyl methacrylate) nanocapsules and the phase transition behavior of the n-hexadecane studied. A sigmoidal correlation was found between the binary composition of the encapsulated oil and the oil formulation prior to encapsulation. At low 1-octanol fractions in the synthesis, almost no alcohol was encapsulated, but at high 1-octanol fractions, the capsules were enriched in alcohol. The freezing point of the encapsulated n-hexadecane was considerably lower than in the bulk phase. This freezing point was further reduced as the radius of the particle was reduced, which is expected from the Gibbs-Thompson equation. The extracted value at infinite radii was, however, 14 °C below the bulk freezing point. The colligative effect of 1-octanol on the freezing point of n-hexadecane, i.e., dT(f)/dx(m), where x(m) is the mass fraction of 1-octanol, was nearly identical to that measured in the bulk system. The specific enthalpy of freezing for the encapsulated system was considerably different from the bulk system. In the bulk system, the freezing enthalpy for n-hexadecane was nearly constant up to 60% mass of 1-octanol. The freezing enthalpy for the encapsulated n-hexadecane showed greater variation with % mass 1-octanol, and had a considerably lower absolute value than the bulk system.
    MeSH term(s) 1-Octanol/chemistry ; Alkanes/chemistry ; Methacrylates/chemistry ; Nanoparticles/chemistry ; Nanotechnology ; Particle Size ; Phase Transition ; Solutions ; Surface Properties
    Chemical Substances Alkanes ; Methacrylates ; Solutions ; n-hexadecane (F8Z00SHP6Q) ; 1-Octanol (NV1779205D)
    Language English
    Publishing date 2012-04-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/jp211459j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Phase Transitions of n-Hexadecane in Nanoencapsulated Binary Solutions of n-Hexadecane and 1-Octanol

    Tubbs, Kyle W / Nguyen Vincent T / Adalsteinsson Thorsteinn

    Journal of physical chemistry. 2012 Apr. 05, v. 116, no. 13

    2012  

    Abstract: Binary solutions of n-hexadecane and 1-octanol were encapsulated within poly(tert-butyl methacrylate) nanocapsules and the phase transition behavior of the n-hexadecane studied. A sigmoidal correlation was found between the binary composition of the ... ...

    Abstract Binary solutions of n-hexadecane and 1-octanol were encapsulated within poly(tert-butyl methacrylate) nanocapsules and the phase transition behavior of the n-hexadecane studied. A sigmoidal correlation was found between the binary composition of the encapsulated oil and the oil formulation prior to encapsulation. At low 1-octanol fractions in the synthesis, almost no alcohol was encapsulated, but at high 1-octanol fractions, the capsules were enriched in alcohol. The freezing point of the encapsulated n-hexadecane was considerably lower than in the bulk phase. This freezing point was further reduced as the radius of the particle was reduced, which is expected from the Gibbs–Thompson equation. The extracted value at infinite radii was, however, 14 °C below the bulk freezing point. The colligative effect of 1-octanol on the freezing point of n-hexadecane, i.e., dTf/dxₘ, where xₘ is the mass fraction of 1-octanol, was nearly identical to that measured in the bulk system. The specific enthalpy of freezing for the encapsulated system was considerably different from the bulk system. In the bulk system, the freezing enthalpy for n-hexadecane was nearly constant up to 60% mass of 1-octanol. The freezing enthalpy for the encapsulated n-hexadecane showed greater variation with % mass 1-octanol, and had a considerably lower absolute value than the bulk system.
    Keywords alcohols ; encapsulation ; enthalpy ; equations ; freezing ; freezing point ; hexadecane ; nanocapsules ; oils
    Language English
    Dates of publication 2012-0405
    Size p. 3954-3960.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1520-5207
    DOI 10.1021%2Fjp211459j
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience.

    Evans, Cory J / Olson, John M / Mondal, Bama Charan / Kandimalla, Pratyush / Abbasi, Ariano / Abdusamad, Mai M / Acosta, Osvaldo / Ainsworth, Julia A / Akram, Haris M / Albert, Ralph B / Alegria-Leal, Elitzander / Alexander, Kai Y / Ayala, Angelica C / Balashova, Nataliya S / Barber, Rebecca M / Bassi, Harmanjit / Bennion, Sean P / Beyder, Miriam / Bhatt, Kush V /
    Bhoot, Chinmay / Bradshaw, Aaron W / Brannigan, Tierney G / Cao, Boyu / Cashell, Yancey Y / Chai, Timothy / Chan, Alex W / Chan, Carissa / Chang, Inho / Chang, Jonathan / Chang, Michael T / Chang, Patrick W / Chang, Stephen / Chari, Neel / Chassiakos, Alexander J / Chen, Iris E / Chen, Vivian K / Chen, Zheying / Cheng, Marsha R / Chiang, Mimi / Chiu, Vivian / Choi, Sharon / Chung, Jun Ho / Contreras, Liset / Corona, Edgar / Cruz, Courtney J / Cruz, Renae L / Dang, Jefferson M / Dasari, Suhas P / De La Fuente, Justin R O / Del Rio, Oscar M A / Dennis, Emily R / Dertsakyan, Petros S / Dey, Ipsita / Distler, Rachel S / Dong, Zhiqiao / Dorman, Leah C / Douglass, Mark A / Ehresman, Allysen B / Fu, Ivy H / Fua, Andrea / Full, Sean M / Ghaffari-Rafi, Arash / Ghani, Asmar Abdul / Giap, Bosco / Gill, Sonia / Gill, Zafar S / Gills, Nicholas J / Godavarthi, Sindhuja / Golnazarian, Talin / Goyal, Raghav / Gray, Ricardo / Grunfeld, Alexander M / Gu, Kelly M / Gutierrez, Natalia C / Ha, An N / Hamid, Iman / Hanson, Ashley / Hao, Celesti / He, Chongbin / He, Mengshi / Hedtke, Joshua P / Hernandez, Ysrael K / Hlaing, Hnin / Hobby, Faith A / Hoi, Karen / Hope, Ashley C / Hosseinian, Sahra M / Hsu, Alice / Hsueh, Jennifer / Hu, Eileen / Hu, Spencer S / Huang, Stephanie / Huang, Wilson / Huynh, Melanie / Javier, Carmen / Jeon, Na Eun / Ji, Sunjong / Johal, Jasmin / John, Amala / Johnson, Lauren / Kadakia, Saurin / Kakade, Namrata / Kamel, Sarah / Kaur, Ravinder / Khatra, Jagteshwar S / Kho, Jeffrey A / Kim, Caleb / Kim, Emily Jin-Kyung / Kim, Hee Jong / Kim, Hyun Wook / Kim, Jin Hee / Kim, Seong Ah / Kim, Woo Kyeom / Kit, Brian / La, Cindy / Lai, Jonathan / Lam, Vivian / Le, Nguyen Khoi / Lee, Chi Ju / Lee, Dana / Lee, Dong Yeon / Lee, James / Lee, Jason / Lee, Jessica / Lee, Ju-Yeon / Lee, Sharon / Lee, Terrence C / Lee, Victoria / Li, Amber J / Li, Jialing / Libro, Alexandra M / Lien, Irvin C / Lim, Mia / Lin, Jeffrey M / Liu, Connie Y / Liu, Steven C / Louie, Irene / Lu, Shijia W / Luo, William Y / Luu, Tiffany / Madrigal, Josef T / Mai, Yishan / Miya, Darron I / Mohammadi, Mina / Mohanta, Sayonika / Mokwena, Tebogo / Montoya, Tonatiuh / Mould, Dallas L / Murata, Mark R / Muthaiya, Janani / Naicker, Seethim / Neebe, Mallory R / Ngo, Amy / Ngo, Duy Q / Ngo, Jamie A / Nguyen, Anh T / Nguyen, Huy C X / Nguyen, Rina H / Nguyen, Thao T T / Nguyen, Vincent T / Nishida, Kevin / Oh, Seo-Kyung / Omi, Kristen M / Onglatco, Mary C / Almazan, Guadalupe Ortega / Paguntalan, Jahzeel / Panchal, Maharshi / Pang, Stephanie / Parikh, Harin B / Patel, Purvi D / Patel, Trisha H / Petersen, Julia E / Pham, Steven / Phan-Everson, Tien M / Pokhriyal, Megha / Popovich, Davis W / Quaal, Adam T / Querubin, Karl / Resendiz, Anabel / Riabkova, Nadezhda / Rong, Fred / Salarkia, Sarah / Sama, Nateli / Sang, Elaine / Sanville, David A / Schoen, Emily R / Shen, Zhouyang / Siangchin, Ken / Sibal, Gabrielle / Sin, Garuem / Sjarif, Jasmine / Smith, Christopher J / Soeboer, Annisa N / Sosa, Cristian / Spitters, Derek / Stender, Bryan / Su, Chloe C / Summapund, Jenny / Sun, Beatrice J / Sutanto, Christine / Tan, Jaime S / Tan, Nguon L / Tangmatitam, Parich / Trac, Cindy K / Tran, Conny / Tran, Daniel / Tran, Duy / Tran, Vina / Truong, Patrick A / Tsai, Brandon L / Tsai, Pei-Hua / Tsui, C Kimberly / Uriu, Jackson K / Venkatesh, Sanan / Vo, Maique / Vo, Nhat-Thi / Vo, Phuong / Voros, Timothy C / Wan, Yuan / Wang, Eric / Wang, Jeffrey / Wang, Michael K / Wang, Yuxuan / Wei, Siman / Wilson, Matthew N / Wong, Daniel / Wu, Elliott / Xing, Hanning / Xu, Jason P / Yaftaly, Sahar / Yan, Kimberly / Yang, Evan / Yang, Rebecca / Yao, Tony / Yeo, Patricia / Yip, Vivian / Yogi, Puja / Young, Gloria Chin / Yung, Maggie M / Zai, Alexander / Zhang, Christine / Zhang, Xiao X / Zhao, Zijun / Zhou, Raymond / Zhou, Ziqi / Abutouk, Mona / Aguirre, Brian / Ao, Chon / Baranoff, Alexis / Beniwal, Angad / Cai, Zijie / Chan, Ryan / Chien, Kenneth Chang / Chaudhary, Umar / Chin, Patrick / Chowdhury, Praptee / Dalie, Jamlah / Du, Eric Y / Estrada, Alec / Feng, Erwin / Ghaly, Monica / Graf, Rose / Hernandez, Eduardo / Herrera, Kevin / Ho, Vivien W / Honeychurch, Kaitlyn / Hou, Yurianna / Huang, Jo M / Ishii, Momoko / James, Nicholas / Jang, Gah-Eun / Jin, Daphne / Juarez, Jesse / Kesaf, Ayse Elif / Khalsa, Sat Kartar / Kim, Hannah / Kovsky, Jenna / Kuang, Chak Lon / Kumar, Shraddha / Lam, Gloria / Lee, Ceejay / Lee, Grace / Li, Li / Lin, Joshua / Liu, Josephine / Ly, Janice / Ma, Austin / Markovic, Hannah / Medina, Cristian / Mungcal, Jonelle / Naranbaatar, Bilguudei / Patel, Kayla / Petersen, Lauren / Phan, Amanda / Phung, Malcolm / Priasti, Nadiyah / Ruano, Nancy / Salim, Tanveer / Schnell, Kristen / Shah, Paras / Shen, Jinhua / Stutzman, Nathan / Sukhina, Alisa / Tian, Rayna / Vega-Loza, Andrea / Wang, Joyce / Wang, Jun / Watanabe, Rina / Wei, Brandon / Xie, Lillian / Ye, Jessica / Zhao, Jeffrey / Zimmerman, Jill / Bracken, Colton / Capili, Jason / Char, Andrew / Chen, Michel / Huang, Pingdi / Ji, Sena / Kim, Emily / Kim, Kenneth / Ko, Julie / Laput, Sean Louise G / Law, Sam / Lee, Sang Kuk / Lee, Olivia / Lim, David / Lin, Eric / Marik, Kyle / Mytych, Josh / O'Laughlin, Andie / Pak, Jensen / Park, Claire / Ryu, Ruth / Shinde, Ashwin / Sosa, Manny / Waite, Nick / Williams, Mane / Wong, Richard / Woo, Jocelyn / Woo, Jonathan / Yepuri, Vishaal / Yim, Dorothy / Huynh, Dan / Wijiewarnasurya, Dinali / Shapiro, Casey / Levis-Fitzgerald, Marc / Jaworski, Leslie / Lopatto, David / Clark, Ira E / Johnson, Tracy / Banerjee, Utpal

    G3 (Bethesda, Md.)

    2021  Volume 11, Issue 1

    Abstract: Undergraduate students participating in the UCLA Undergraduate Research Consortium for Functional Genomics (URCFG) have conducted a two-phased screen using RNA interference (RNAi) in combination with fluorescent reporter proteins to identify genes ... ...

    Abstract Undergraduate students participating in the UCLA Undergraduate Research Consortium for Functional Genomics (URCFG) have conducted a two-phased screen using RNA interference (RNAi) in combination with fluorescent reporter proteins to identify genes important for hematopoiesis in Drosophila. This screen disrupted the function of approximately 3500 genes and identified 137 candidate genes for which loss of function leads to observable changes in the hematopoietic development. Targeting RNAi to maturing, progenitor, and regulatory cell types identified key subsets that either limit or promote blood cell maturation. Bioinformatic analysis reveals gene enrichment in several previously uncharacterized areas, including RNA processing and export and vesicular trafficking. Lastly, the participation of students in this course-based undergraduate research experience (CURE) correlated with increased learning gains across several areas, as well as increased STEM retention, indicating that authentic, student-driven research in the form of a CURE represents an impactful and enriching pedagogical approach.
    MeSH term(s) Animals ; Blood Cells ; Drosophila/genetics ; Genomics/education ; Humans ; Students ; Universities
    Language English
    Publishing date 2021-02-12
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2629978-1
    ISSN 2160-1836 ; 2160-1836
    ISSN (online) 2160-1836
    ISSN 2160-1836
    DOI 10.1093/g3journal/jkaa028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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