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Article ; Online: Prenatal diagnosis of non-typical Chiari malformation type I associated with de novo Nuclear Factor I A gene mutation: a case report.

Tomai, Xuan-Hong / Nguyen, Huu-Trung / Nguyen Thi, Thanh-Truc / Nguyen, Tuan-Anh / Nguyen, Thuy-Vy

2024 Volume 18, Issue 1, Page(s) 90

Abstract: Background: Chiari malformation is one of the most common Central nervous system (CNS) abnormalities that can be detected in routine fetal scanning. Chiari malformation type I (CMI) is a congenital defect characterized by a displacement of the ... ...

Abstract	Background: Chiari malformation is one of the most common Central nervous system (CNS) abnormalities that can be detected in routine fetal scanning. Chiari malformation type I (CMI) is a congenital defect characterized by a displacement of the cerebellar tonsils through the foramen magnum. The etiology of CMI has not been well established and suggested having multifactorial contributions, especially genetic deletion. Clinical characteristics of this anomaly may express in different symptoms from neurological dysfunction and/or skeletal abnormalities in the later age, but it is rarely reported in pregnancy. Case presentation: We present a case in which the Chiari malformation type I was diagnosed with comorbidities of facial anomalies (flatting forehead and micrognathia) and muscular-skeletal dysmorphologies (clenched hands and clubfeet) at the 24 Conclusion: CMI may only represent with facial abnormalities and muscle-skeletal malformations at the early stage of pregnancy, which may also alert an adverse outcome. A novel heterozygous NFIA gene mutation identified after birth helps to confirm prenatal diagnosis of CMI and to provide an appropriate consultation.
MeSH term(s)	Male ; Pregnancy ; Female ; Infant, Newborn ; Humans ; Adult ; Arnold-Chiari Malformation/diagnosis ; Arnold-Chiari Malformation/genetics ; NFI Transcription Factors/genetics ; Prenatal Diagnosis ; Amniocentesis ; Mutation ; Magnetic Resonance Imaging
Chemical Substances	NFI Transcription Factors
Language	English
Publishing date	2024-02-13
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2269805-X
ISSN	1752-1947 ; 1752-1947
ISSN (online)	1752-1947
ISSN	1752-1947
DOI	10.1186/s13256-024-04361-1
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Article ; Online: Self-care knowledge in patients with intestinal stomas in a selected hospital in the south of Viet Nam: A descriptive cross-sectional study.

Ngo, Thi Dung / Hawks, Miranda / Nguyen, Thi Thanh Truc / Nguyen, Thi Ngoc Han / Nguyen, Hong Thiep / Mai, Nguyen Thanh Truc

Belitung nursing journal

2023 Volume 9, Issue 4, Page(s) 331–338

Abstract: Background: Intestinal stomas are surgical interventions that have an impact on both physical and psychological health, necessitating patient self-care. Insufficient knowledge regarding peristomal skin care, prevention, and treatment of potential ... ...

Abstract	Background: Intestinal stomas are surgical interventions that have an impact on both physical and psychological health, necessitating patient self-care. Insufficient knowledge regarding peristomal skin care, prevention, and treatment of potential problems can lead to an increase in stoma-related complications. Objective: This study aimed to assess patients' knowledge of self-care for intestinal stomas and examine the relationship between background information and self-care knowledge. Methods: A descriptive cross-sectional study was conducted from December 2021 to December 2022 at the Can Tho University of Medicine and Pharmacy Hospital in Vietnam, involving 74 participants with intestinal stomas. A questionnaire consisting of 24 closed-ended questions was used to evaluate participants' knowledge of self-care for intestinal stomas. Descriptive statistics, Chi-square, and Fisher's exact tests were employed for data analysis. Results: The findings revealed that 54.1% of participants had good knowledge of general self-care for intestinal stomas. The distribution of good knowledge among participants was as follows: basic knowledge (66.2%), self-care practice (56.8%), recognizing and managing complications (31.1%), and dietary knowledge (64.8%). Significant relationships were observed between participants' self-care knowledge and their education level ( Conclusion: The proportion of participants with good knowledge of self-care for intestinal stomas was relatively low, and it was associated with individuals' education level, marital status, nurses' education, and hospitalization. This study highlights the need for ongoing development of educational programs on self-care for intestinal stomas. These programs should be tailored to address the specific needs of each patient and aim to improve their self-care knowledge in a meaningful and sustainable manner. By investing in patient education, healthcare professionals, particularly nurses, can assist individuals with intestinal stomas in achieving better outcomes and preventing potential complications.
Language	English
Publishing date	2023-08-28
Publishing country	Indonesia
Document type	Journal Article
ISSN	2477-4073
ISSN (online)	2477-4073
DOI	10.33546/bnj.2711
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Article ; Online: Prevalence of common autosomal recessive mutation carriers in women in the Southern Vietnam following the application of expanded carrier screening.

To-Mai, Xuan-Hong / Nguyen, Huu-Trung / Nguyen-Thi, Thanh-Truc / Nguyen, Thuy-Vy / Nguyen-Thi, My-Nuong / Thai, Ke-Quan / Lai, Minh-Thi / Nguyen, Tuan-Anh

Scientific reports

2024 Volume 14, Issue 1, Page(s) 7461

Abstract: The common autosomal recessive (AR) mutation carrier is still unknown in Vietnam. This study aims to identify the most common AR gene mutation carriers in women of reproductive age to build a Vietnamese-specific carrier screening panel for AR and X- ... ...

Abstract	The common autosomal recessive (AR) mutation carrier is still unknown in Vietnam. This study aims to identify the most common AR gene mutation carriers in women of reproductive age to build a Vietnamese-specific carrier screening panel for AR and X-linked disorders in the preconception and prenatal healthcare program. A cross-sectional study was conducted at University Medical Center-Branch 2 in Ho Chi Minh City from December 1st, 2020, to June 30th, 2023. 338 women have consented to take a 5 mL blood test to identify 540 recessive genes. The carrier screening panel was designed based on the American College of Medical Genetics and Genomics (ACMG)-recommended genes and suggestions from 104 clinical experts in Vietnam. Obstetricians and genetic experts counseled all positive testing results to discuss the possibility of recessive diseases in their offspring. The most common recessive disorders were defined at a prevalence of 1 in 60 or greater, and those were added to a Vietnamese-specific carrier screening panel. 338 non-pregnant and pregnant women underwent the expanded carrier screening (ECS). The carrier frequency was 63.6%, in which 215 women carried at least one AR gene mutation. GJB2 hearing impairment was identified as the most common chronic condition (1 in 5). The second most common AR disorder was beta-thalassemia (1 in 16), followed by cystic fibrosis (1 in 23), G6PD deficiency (1 in 28), Wilson's disease (1 in 31), Usher's syndrome (1 in 31), and glycogen storage disease (1 in 56). Seven common recessive genes were added in ethnic-based carrier screening. Women in the South of Vietnam have been carried for many recessive conditions at high frequency, such as hearing impairment, genetic anemia, and cystic fibrosis. It is necessary to implement a preconception and prenatal screening program by using seven widely popular AR genes in a Vietnamese-specific carrier screening panel to reduce the burden related to AR and X-linked disorders.
MeSH term(s)	Humans ; Female ; Pregnancy ; Genetic Testing/methods ; Genetic Carrier Screening/methods ; Vietnam/epidemiology ; Cystic Fibrosis/genetics ; Prevalence ; Cross-Sectional Studies ; Mutation ; Hearing Loss/genetics
Language	English
Publishing date	2024-03-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-57513-0
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Article ; Online: Optimization Removal of COD and Nitrogen at Different Hydraulic Retention Times in Biocord-Integrated Fixed-Film Activated Sludge System

Nguyen Thi Tuyet Nhi / Phan Thi Thuy Van / Nguyen Thi Thao / Nguyen Thi Thanh Truc / Tran Le Truong Khanh Hung / Do Thi Ngoc Tay / Huynh Tan Nhut / Nguyen Trung Hiep

Environment and Natural Resources Journal, Vol 20, Iss 4, Pp 411-

2022 Volume 418

Abstract: Although conventional activated sludge has been demonstrated to be a feasible approach for extracting nitrogenous chemicals and organic pollutants from wastewater, it still has a number of drawbacks. In this research, a pilot-scale biocord-integrated ... ...

Abstract	Although conventional activated sludge has been demonstrated to be a feasible approach for extracting nitrogenous chemicals and organic pollutants from wastewater, it still has a number of drawbacks. In this research, a pilot-scale biocord-integrated fixed-film activated sludge (Biocord-IFAS) reactor fed with actual domestic wastewater was operated to examine the effect of varying hydraulic retention time (HRT) on the COD and nitrogen removal. The type of material employed in this study is fibrous polypropylene (biocord), which is a major difference. The contribution of the Biocord-IFAS to COD removal efficiency reached 94.2% at HRT of 8 h and gradually decreased to 82.9% when HRT was reduced to 4 h. During the investigation period, a slight decrease in nitrification was found at a shorter HRT. The NH4+-N removal efficiencies at HRTs of 10, 8, 6, and 4 h were 97.8%, 98.7%, 97.1%, and 96.3%, respectively. The average effluent nitrate concentration was 5.3 mg/L with HRTs from 10 to 6 h, but over 30 mg/L with an HRT of 4 h. The SEM analysis results show that microorganisms have formed on the biocord surface. The results of this research have demonstrated the potential application of IFAS reactors in bioremediation procedures employing biocord material with great processing efficiency.
Keywords	ammonium removal ; biocord-ifas ; cod removal ; domestic wastewater ; hydraulic retention time (hrt) ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350
Subject code	660
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Mahidol University
Document type	Article ; Online
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Article ; Online: Novel Removal of Diazinon Pesticide by Adsorption and Photocatalytic Degradation of Visible Light-Driven Fe-TiO2/Bent-Fe Photocatalyst

Nguyen Minh Phuong / Ngoc Chau Chu / Doan Van Thuan / Minh Ngoc Ha / Nguyen Thi Hanh / Huong Do Thi Viet / Nguyen Thi Minh Thu / Pham Van Quan / Nguyen Thi Thanh Truc

Journal of Chemistry, Vol

2019 Volume 2019

Abstract: In the study, Fe was used as a dopant to enhance photocatalytic activity of TiO2. Then, the Fe-doped TiO2 was deposited on bentonite, which was pillared by Fe. The synthesized materials were characterized by SEM, XRD, UV-Vis, BET, and point of zero ... ...

Abstract	In the study, Fe was used as a dopant to enhance photocatalytic activity of TiO2. Then, the Fe-doped TiO2 was deposited on bentonite, which was pillared by Fe. The synthesized materials were characterized by SEM, XRD, UV-Vis, BET, and point of zero charge (pHPZC). Then, the synthesized materials were used for diazinon removal under both dark and visible light conditions to investigate adsorption and photocatalytic degradation abilities of the synthesized materials. The maximum diazinon adsorption capacity of the synthesized Fe-TiO2/Bent-Fe was 27.03 mg/g. The obtained results indicated that the Fe-TiO2/Bent-Fe exhibited high photocatalytic degradation activity for removal of diazinon even under visible light. The diazinon removal experiments were also conducted using different photocatalyst dosages, under different pH and light sources to figure the optimal conditions for removal processes. The obtained results indicated that optimal photocatalyst dosage and pH were 0.5 g/L and 4.5, respectively. Finally, the natural light generated from solar could be suitable used for diazinon removal by the synthesized Fe-TiO2/Bent-Fe.
Keywords	Chemistry ; QD1-999
Subject code	660
Language	English
Publishing date	2019-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Evaluation of heavy metals in hazardous automobile shredder residue thermal residue and immobilization with novel nano-size calcium dispersed reagent

Lee, Chi-Hyeon / Nguyen Thi Thanh Truc / Byeong-Kyu Lee / Yoshiharu Mitoma / Srinivasa Reddy Mallampati

Journal of hazardous materials. 2015 Oct. 15, v. 296

2015

Abstract: This study was conducted to synthesize and apply a nano-size calcium dispersed reagent as an immobilization material for heavy metal-contaminated automobile shredder residues (ASR) dust/thermal residues in dry condition. Simple mixing with a nanometallic ...

Abstract	This study was conducted to synthesize and apply a nano-size calcium dispersed reagent as an immobilization material for heavy metal-contaminated automobile shredder residues (ASR) dust/thermal residues in dry condition. Simple mixing with a nanometallic Ca/CaO/PO4 dispersion mixture immobilized 95â100% of heavy metals in ASR dust/thermal residues (including bottom ash, cavity ash, boiler and bag filter ash). The quantity of heavy metals leached from thermal residues after treatment by nanometallic Ca/CaO/PO4 was lower than the Korean standard regulatory limit for hazardous waste landfills. The morphology and elemental composition of the nanometallic Ca/CaO-treated ASR residue were characterized by field emission scanning election microscopy combined with electron dispersive spectroscopy (FE-SEM/EDS). The results indicated that the amounts of heavy metals detectable on the ASR thermal residue surface decreased and the Ca/PO4 mass percent increased. X-ray diffraction (XRD) pattern analysis indicated that the main fraction of enclosed/bound materials on ASR residue included Ca/PO4â associated crystalline complexes, and that immobile Ca/PO4 salts remarkably inhibited the desorption of heavy metals from ASR residues. These results support the potential use of nanometallic Ca/CaO/PO4 as a simple, suitable and highly efficient material for the gentle immobilization of heavy metals in hazardous ASR thermal residue in dry condition.
Keywords	X-ray diffraction ; automobiles ; bottom ash ; calcium ; calcium oxide ; desorption ; elemental composition ; hazardous waste ; heavy metals ; landfills ; microscopy ; mixing ; phosphates ; spectroscopy
Language	English
Dates of publication	2015-1015
Size	p. 239-247.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2015.04.039
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Impact of refugee influx on the epidemiology of late-presenting HIV-infected pregnant women and mother-to-child transmission: comparing a southern and northern medical centre in Germany.

Singer, Katharina / Schulze-Sturm, Ulf / Alba-Alejandre, Irene / Hollwitz, Bettina / Nguyen, Thi Thanh Truc / Sollinger, Franz / Eberle, Josef / Hübner, Johannes / Kobbe, Robin / Genzel-Boroviczény, Orsolya / von Both, Ulrich

Infection

2019 Volume 47, Issue 5, Page(s) 847–852

Abstract: Purpose: Due to early antenatal screening and treatment, HIV mother-to-child transmission (MTCT) rarely occurs in Germany. The study aimed to investigate the impact on prevalence of HIV infection in the antenatal population and the incidence of late- ... ...

Abstract	Purpose: Due to early antenatal screening and treatment, HIV mother-to-child transmission (MTCT) rarely occurs in Germany. The study aimed to investigate the impact on prevalence of HIV infection in the antenatal population and the incidence of late-presenting HIV-infected mothers attributable to increased numbers of refugees. Methods: Retrospective analysis and comparison were performed for all deliveries in HIV-infected pregnant women presenting to medical care in Munich (southern Germany) and Hamburg (northern Germany) covering two time periods, A (2010-2012) and B (2013-2015). Results: In Munich, deliveries in HIV-infected pregnant women increased 1.6-fold from period A (n = 50) to B (n = 79) with late-presenting cases rising significantly from 2% (1/50) in period A to 13% (10/79) in B. In contrast, late-presenting cases in Hamburg decreased from 14% (14/100) in period A to 7% (7/107) in B, while the total number of HIV-infected women giving birth remained stable. From 2010 to 2015, one late-presenting pregnant woman transmitted HIV in Munich by presumed in utero mode of infection (case reviewed here), while no MTCT occurred in Hamburg. Conclusions: HIV infections diagnosed late in pregnancy and leading to delayed ART initiation are rising in Munich compared to Hamburg. Antenatal care of HIV-infected pregnant women in Munich appears to have been more affected by the recent refugee influx than Hamburg. Our study highlights the importance of screening all pregnant women for HIV early in pregnancy and providing timely health care access for pregnant refugees and asylum seekers to effectively prevent MTCT in Germany.
MeSH term(s)	Adult ; Anti-HIV Agents/therapeutic use ; Female ; Geography ; Germany/epidemiology ; HIV Infections/diagnosis ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; HIV-1 ; Health Services Accessibility ; Humans ; Infectious Disease Transmission, Vertical/statistics & numerical data ; Pregnancy ; Pregnancy Complications, Infectious/epidemiology ; Pregnancy Complications, Infectious/virology ; Prevalence ; Refugees ; Retrospective Studies ; Time-to-Treatment ; Young Adult
Chemical Substances	Anti-HIV Agents
Language	English
Publishing date	2019-06-12
Publishing country	Germany
Document type	Case Reports ; Comparative Study ; Journal Article
ZDB-ID	185104-4
ISSN	1439-0973 ; 0300-8126 ; 0173-2129
ISSN (online)	1439-0973
ISSN	0300-8126 ; 0173-2129
DOI	10.1007/s15010-019-01332-3
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Article ; Online: Reducing Hematologic Toxicity With Short Course Postexposure Prophylaxis With Zidovudine for HIV-1 Exposed Infants With Low Transmission Risk.

Nguyen, Thi Thanh Truc / Kobbe, Robin / Schulze-Sturm, Ulf / Blohm, Martin / Hollwitz, Bettina / Hertling, Sandra / Becker, Christina / Oommen, Prasad Thomas / Laws, Hans-Jürgen / Martignoni, Franca / Ole Jensen, Björn-Erik / Olah, Karen / Schmidtke, Susanne / Kreuels, Benno / Vasconcelos, Malte Kohns / Neubert, Jennifer

The Pediatric infectious disease journal

2019 Volume 38, Issue 7, Page(s) 727–730

Abstract: Using retrospectively collected data from 383 infants born to HIV-1-infected mothers receiving antiretroviral therapy, we compared transmission rates and hematologic toxicity between infants receiving 2-week (short course) versus longer duration ... ...

Abstract	Using retrospectively collected data from 383 infants born to HIV-1-infected mothers receiving antiretroviral therapy, we compared transmission rates and hematologic toxicity between infants receiving 2-week (short course) versus longer duration zidovudine postexposure prophylaxis. Short course resulted in lower hematologic toxicity without evidence of increased vertical transmission risk.
MeSH term(s)	Anti-HIV Agents/administration & dosage ; Anti-HIV Agents/adverse effects ; Drug-Related Side Effects and Adverse Reactions/epidemiology ; Drug-Related Side Effects and Adverse Reactions/prevention & control ; Female ; HIV Infections/prevention & control ; Hematologic Diseases/chemically induced ; Hematologic Diseases/epidemiology ; Humans ; Infant ; Infant, Newborn ; Infectious Disease Transmission, Vertical/prevention & control ; Male ; Pregnancy ; Retrospective Studies ; Zidovudine/administration & dosage ; Zidovudine/adverse effects
Chemical Substances	Anti-HIV Agents ; Zidovudine (4B9XT59T7S)
Language	English
Publishing date	2019-06-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	392481-6
ISSN	1532-0987 ; 0891-3668
ISSN (online)	1532-0987
ISSN	0891-3668
DOI	10.1097/INF.0000000000002357
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Article ; Online: Preclinical Immune Response and Safety Evaluation of the Protein Subunit Vaccine Nanocovax for COVID-19.

Tran, Thi Nhu Mai / May, Bruce Pearson / Ung, Trong Thuan / Nguyen, Mai Khoi / Nguyen, Thi Thuy Trang / Dinh, Van Long / Doan, Chinh Chung / Tran, The Vinh / Khong, Hiep / Nguyen, Thi Thanh Truc / Hua, Hoang Quoc Huy / Nguyen, Viet Anh / Ha, Tan Phat / Phan, Dang Luu / Nguyen, Truong An / Bui, Thi Ngoc / Tu, Tieu My / Nguyen, Thi Theo / Le, Thi Thuy Hang /

Dong, Thi Lan / Huynh, Trong Hieu / Ho, Phien Huong / Le, Nguyen Thanh Thao / Truong, Cong Thao / Pham, Hoang Phi / Luong, Cong Y / Y, Nie Lim / Cao, Minh Ngoc / Nguyen, Duy Khanh / Le, Thi Thanh / Vuong, Duc Cuong / Nguyen, Le Khanh Hang / Do, Minh Si

Frontiers in immunology

2021 Volume 12, Page(s) 766112

Abstract: The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global health concern. The development of vaccines with high immunogenicity and safety is crucial for controlling the ...

Abstract	The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global health concern. The development of vaccines with high immunogenicity and safety is crucial for controlling the global COVID-19 pandemic and preventing further illness and fatalities. Here, we report the development of a SARS-CoV-2 vaccine candidate, Nanocovax, based on recombinant protein production of the extracellular (soluble) portion of the spike (S) protein of SARS-CoV-2. The results showed that Nanocovax induced high levels of S protein-specific IgG and neutralizing antibodies in three animal models: BALB/c mouse, Syrian hamster, and a non-human primate (
MeSH term(s)	Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; COVID-19/prevention & control ; COVID-19 Vaccines/immunology ; COVID-19 Vaccines/toxicity ; Cricetinae ; Immunogenicity, Vaccine/immunology ; Macaca ; Mice ; Rats ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/immunology ; Vaccines, Synthetic/immunology ; Vaccines, Synthetic/toxicity
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral ; COVID-19 Vaccines ; Spike Glycoprotein, Coronavirus ; Vaccines, Synthetic ; spike protein, SARS-CoV-2
Language	English
Publishing date	2021-12-06
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2021.766112
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