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  1. Article ; Online: Sleep Disorders in Patients with Severe COVID-19 Treated in the Intensive Care Unit: A Real-Life Descriptive Study in Vietnam.

    Duong-Quy, Sy / Tang-Thi-Thao, Tram / Huynh-Truong-Anh, Duc / Hoang-Thi-Xuan, Huong / Nguyen-Van, Toi / Nguyen-Tuan, Anh / Tran-Thi-Cam, Tu / Bui-Diem, Khue / Vu-Tran-Thien, Quan / Tran-Duc, Si / Nguyen-Ngoc-Phuong, Thu / Nguyen-Nhu, Vinh / Nguyen-Duy, Thai

    Discovery medicine

    2024  Volume 36, Issue 183, Page(s) 690–698

    Abstract: Background: Coronavirus disease 2019 (COVID-19) patients with sleep disorders may be at greater risk for respiratory exacerbation or death compared to those without. After being infected with COVID-19, patients have many symptoms related to sleep ... ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) patients with sleep disorders may be at greater risk for respiratory exacerbation or death compared to those without. After being infected with COVID-19, patients have many symptoms related to sleep disorders, especially those with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. This study aimed to evaluate sleep disturbances in patients with severe SARS-CoV-2 infection who were treated in the Intensive Care Unit (ICU).
    Methods: This cross-sectional study used the questionnaire provided by the Vietnam Sleep Disorder Study (ViSDiS) research, elaborated by the Vietnam Society of Sleep Medicine (VSSM). Seventy-seven COVID-19 patients were included.
    Results: There was a significant difference in sleep status before and after SARS-CoV-2 infection among participants. Up to 83% of them reported experiencing insomnia after illness, 60% reported having frequent nightmares, and more than half of participants reported nocturia (
    Conclusion: Sleep problems are highly prevalence among hospitalized patients with severe COVID-19 in the ICU. Healthcare providers should pay attention to sleep problems and their associated symptoms to initiate appropriate treatment to improve severe COVID-19 patients' health status and minimize the risk of death.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/complications ; COVID-19/therapy ; Male ; Female ; Intensive Care Units/statistics & numerical data ; Middle Aged ; Vietnam/epidemiology ; Cross-Sectional Studies ; Sleep Wake Disorders/epidemiology ; SARS-CoV-2 ; Aged ; Adult ; Surveys and Questionnaires ; Sleep Quality ; Severity of Illness Index
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2415544-5
    ISSN 1944-7930 ; 1944-7930
    ISSN (online) 1944-7930
    ISSN 1944-7930
    DOI 10.24976/Discov.Med.202436183.65
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Bradycardia unresponded to atropin testing was successfully treated with therapeutic plasma exchange in a patient with severe COVID-19 complicated by Guillain-Barré syndrome: A case report.

    Duong-Quy, Sy / Huynh-Truong-Anh, Duc / Tran-Xuan, Quynh / Nguyen-Quang, Tien / Nguyen-Thi-Kim, Thanh / Nguyen-Chi, Thanh / Tran-Ngoc-Anh, Thuy / Nguyen-Van-Hoai, Nam / Do-Thi-Thu, Mai / Tang-Thi-Thao, Tram / Bui-Diem, Khue / Hoang-Anh, Tien / Nguyen-Ngoc-Phuong, Thu / Nguyen-Nhu, Vinh

    Frontiers in cardiovascular medicine

    2023  Volume 9, Page(s) 1035896

    Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been an alarming situation worldwide for the past 2 years. The symptoms of coronavirus disease 2019 (COVID-19) are not only confined to the respiratory system but also affect a ...

    Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been an alarming situation worldwide for the past 2 years. The symptoms of coronavirus disease 2019 (COVID-19) are not only confined to the respiratory system but also affect a multitude of organ systems. Bradycardia associated with Guillain-Barré syndrome (GBS) is a rare autonomic and peripheral neurological complication of COVID-19. In this case report, we present the case of a 26-year-old man diagnosed with bradycardia associated with GBS after contracting COVID-19. Initially, this patient had the classical symptoms of COVID-19 and was hospitalized in the intensive care unit (ICU) for acute respiratory distress syndrome (ARDS). Then, he developed weakness in the lower extremities, diminished tendon reflexes, a loss of sensation without sphincter muscle disorders, and bradycardia. His bradycardia did not respond to atropine. The patient was treated concurrently with a high-flow nasal cannula, systemic corticosteroids, anticoagulation, and therapeutic plasma exchange (TPE) for COVID-19-induced ARDS, bradycardia, and GBS. His ARDS and bradycardia improved after the first cycle of TPE and medical treatment. After three cycles of TPE, the patient progressively recovered his muscle strength in the lower limbs and regained peripheral sensation. He was discharged from the hospital in stable condition after 4 weeks of hospitalization and was followed up after 6 months for cardiorespiratory and neurological complications. This case report elucidates the potential difficulties and challenges that physicians may encounter in diagnosing and treating COVID-19-induced bradycardia and GBS during the pandemic outbreak. However, the patient outcomes with the treatment combining the conventional treatment with therapeutic plasma exchange seem to be optimistic.
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.1035896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Personalized Medicine and Obstructive Sleep Apnea.

    Duong-Quy, Sy / Nguyen-Huu, Hoang / Hoang-Chau-Bao, Dinh / Tran-Duc, Si / Nguyen-Thi-Hong, Lien / Nguyen-Duy, Thai / Tang-Thi-Thao, Tram / Phan, Chandat / Bui-Diem, Khue / Vu-Tran-Thien, Quan / Nguyen-Ngoc-Phuong, Thu / Nguyen-Nhu, Vinh / Le-Thi-Minh, Huong / Craig, Timothy

    Journal of personalized medicine

    2022  Volume 12, Issue 12

    Abstract: Obstructive sleep apnea (OSA) is a common disease that is often under-diagnosed and under-treated in all ages. This is due to differences in morphology, diversity in clinical phenotypes, and differences in diagnosis and treatment of OSA in children and ... ...

    Abstract Obstructive sleep apnea (OSA) is a common disease that is often under-diagnosed and under-treated in all ages. This is due to differences in morphology, diversity in clinical phenotypes, and differences in diagnosis and treatment of OSA in children and adults, even among individuals of the same age. Therefore, a personalized medicine approach to diagnosis and treatment of OSA is necessary for physicians in clinical practice. In children and adults without serious underlying medical conditions, polysomnography at sleep labs may be an inappropriate and inconvenient testing modality compared to home sleep apnea testing. In addition, the apnea-hypopnea index should not be considered as a single parameter for making treatment decisions. Thus, the treatment of OSA should be personalized and based on individual tolerance to sleep-quality-related parameters measured by the microarousal index, harmful effects of OSA on the cardiovascular system related to severe hypoxia, and patients' comorbidities. The current treatment options for OSA include lifestyle modification, continuous positive airway pressure (CPAP) therapy, oral appliance, surgery, and other alternative treatments. CPAP therapy has been recommended as a cornerstone treatment for moderate-to-severe OSA in adults. However, not all patients can afford or tolerate CPAP therapy. This narrative review seeks to describe the current concepts and relevant approaches towards personalized management of patients with OSA, according to pathophysiology, cluster analysis of clinical characteristics, adequate combined therapy, and the consideration of patients' expectations.
    Language English
    Publishing date 2022-12-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm12122034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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