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  1. Article: Photo-Excited Metasurface for Tunable Terahertz Reflective Circular Polarization Conversion and Anomalous Beam Deflection at Two Frequencies Independently.

    Xu, Zhixiang / Ni, Cheng / Cheng, Yongzhi / Dong, Linhui / Wu, Ling

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 12

    Abstract: In this paper, a photo-excited metasurface (MS) based on hybrid patterned photoconductive silicon (Si) structures was proposed in the terahertz (THz) region, which can realize the tunable reflective circular polarization (CP) conversion and beam ... ...

    Abstract In this paper, a photo-excited metasurface (MS) based on hybrid patterned photoconductive silicon (Si) structures was proposed in the terahertz (THz) region, which can realize the tunable reflective circular polarization (CP) conversion and beam deflection effect at two frequencies independently. The unit cell of the proposed MS consists of a metal circular-ring (CR), Si ellipse-shaped-patch (ESP) and circular-double-split-ring (CDSR) structure, a middle dielectric substrate, and a bottom metal ground plane. By altering the external infrared-beam pumping power, it is possible to modify the electric conductivity of both the Si ESP and CDSR components. By varying the conductivity of the Si array in this manner, the proposed MS can achieve a reflective CP conversion efficiency that ranges from 0% to 96.6% at a lower frequency of 0.65 THz, and from 0% to 89.3% at a higher frequency of 1.37 THz. Furthermore, the corresponding modulation depth of this MS is as high as 96.6% and 89.3% at two distinct and independent frequencies, respectively. Moreover, at the lower and higher frequencies, the 2π phase shift can also be achieved by respectively rotating the oriented angle (α
    Language English
    Publishing date 2023-06-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13121846
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tracking spatio-temporal dynamics of harmful algal blooms using long-term MODIS observations of Chaohu Lake in China from 2000 to 2021

    Zhou, Ting / Li, Yan / Jiang, Bo / Alatalo, Juha M. / Li, Chen / Ni, Cheng

    Ecological Indicators. 2023 Feb., v. 146 p.109842-

    2023  

    Abstract: Harmful algal blooms (HABs) have long been a critical threat to environmental safety and health, especially in inland lakes with rapidly growing socioeconomic development. Although satellite remote sensing provides an efficient manner to observe floating ...

    Abstract Harmful algal blooms (HABs) have long been a critical threat to environmental safety and health, especially in inland lakes with rapidly growing socioeconomic development. Although satellite remote sensing provides an efficient manner to observe floating algae blooms, tracing and capturing the distribution of HABs in water bodies remains challenging for their high dynamics in both spatial and temporal dimensions. This study analyzed the spatio-temporal dynamics of HABs in Chaohu Lake, China, from 2000 to 2021. Daily MODIS remote sensing observations, including 7926 images, were utilized. The Floating Algae Index (FAI) was applied to each image to detect the area and severity of HABs. Results show that the HABs in Chaohu Lake have generally been increasing in the past two decades, with two intermittent decreases in 2016-2017 and 2020-2021, and the duration of HABs tended to be longer over the years. HABs were most severe and frequent in the lake's northwestern area. Temperature and precipitation are two main meteorological factors positively correlated with HABs. The fast-growing socio-economy reflected by population and GDP increase lake eutrophication and HABs. However, environment management policies since 2020 have had a significant and rapid influence in decreasing the lake's nutrients, which greatly reduced HABs severity in 2020 and 2021. This study's results further indicate that high-frequency remote sensing observations, although with occasional data missing due to cloud cover, can still perform well in describing HABs, as long as the analysis method is appropriately adopted. This finding provides potential significance for utilizing remote sensing products, especially for highly dynamic object observation where high-quality images are lacking.
    Keywords cloud cover ; eutrophication ; lakes ; poisonous algae ; satellites ; socioeconomic development ; temperature ; China ; Harmful algal blooms (HABs) distribution ; Spatio-temporal dynamics ; Meteorological factor ; Human activities ; Floating algae index ; Chaohu Lake
    Language English
    Dates of publication 2023-02
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 2036774-0
    ISSN 1872-7034 ; 1470-160X
    ISSN (online) 1872-7034
    ISSN 1470-160X
    DOI 10.1016/j.ecolind.2022.109842
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  3. Article: The changing natural history of COPD: summary from the American Thoracic Society Meeting 2016.

    Liang, Ni-Cheng

    Journal of thoracic disease

    2016  Volume 8, Issue Suppl 7, Page(s) S553–5

    Language English
    Publishing date 2016-09-07
    Publishing country China
    Document type Editorial
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2016.07.29
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  4. Article ; Online: [Determination of organic acids and anions in exhaled breath by condensation collection-ion chromatography].

    Gan, Lu / Zhou, Yang-Ye / Fang, Qin-Qin / Xu, Jian-Jun / Chen, Su-Qing / Zhu, Yan / Ni, Cheng-Zhu

    Se pu = Chinese journal of chromatography

    2024  Volume 42, Issue 3, Page(s) 275–281

    Abstract: A non-invasive condensation collection-ion chromatography method was established for the determination of organic acids and anions including lactic acid, formic acid, acetic acid, pyruvic acid, chloride, nitrate, nitrite, and sulfate in the exhaled ... ...

    Abstract A non-invasive condensation collection-ion chromatography method was established for the determination of organic acids and anions including lactic acid, formic acid, acetic acid, pyruvic acid, chloride, nitrate, nitrite, and sulfate in the exhaled breath of humans. The breath exhaled was condensed and collected using a home-made exhaled breath condensation equipment. This equipment included a disposable mouthpiece as a blow-off port, one-way valve and flow meter, cold trap, disposable condensate collection tube placed in the cold trap, and gas outlet. A standard sampling procedure was used. Before collection, the collection temperature and sampling volume were set on the instrument control panel, and sampling was started when the cold-trap temperature dropped to the set value, while maintaining the balance. Subjects were required to gargle with pure water before sampling. During the sampling process, the subjects were required to inhale deeply until the lungs were full of gas and then exhale evenly through the air outlet. When the set volume was collected, the instrument made a prompt sound; then, the collection was immediately ended, the expiration time was recorded, and the average collection flow was calculated according to the expiration time and sampling volume. After collection, the disposable condensation collection tube was immediately taken out, sealed, and stored in the refrigerator at -20 ℃ away from light, and immediately used for further testing. The organic acids and anions in exhaled breath condensation (EBC) were filtered through a 0.22 μm membrane filter before injection and detected by ion chromatography with conductivity detection. Factors such as collection temperature and collection flow rate during condensation collection were optimized. The optimal cooling temperature was set at -15 ℃, and the optimal exhaled breath flow rate was set at 15 L/min. The mobile phase consisted of a mixture of sodium carbonate (1.5 mmol/L) and sodium bicarbonate (3 mmol/L). The flow rate was 0.8 mL/min, and the injection volume was 100 μL. An IC-SA3 column (250 mm×4.0 mm) was used, and the temperature was set at 45 ℃. An ICDS-40A electrodialysis suppressor was used, and the current was set at 150 mA. The linear ranges of the eight organic acids and anions were 0.1-10.0 mg/L; their correlation coefficients (
    MeSH term(s) Humans ; Chlorides ; Pyruvic Acid ; Anions ; Lactic Acid/analysis ; Chromatography ; Acetates/analysis
    Chemical Substances Chlorides ; Pyruvic Acid (8558G7RUTR) ; Anions ; Lactic Acid (33X04XA5AT) ; Acetates
    Language Chinese
    Publishing date 2024-03-18
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 1872-2059
    ISSN (online) 1872-2059
    DOI 10.3724/SP.J.1123.2023.07016
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  5. Article: Transcriptomic analysis and experiments revealed that remimazolam promotes proliferation and G1/S transition in HCT8 cells.

    Wang, Runjia / Li, Shuai / Hu, Han / Hou, Qi / Chu, Huaqing / Hou, Yu / Ni, Cheng / Ran, Yuliang / Zheng, Hui

    Frontiers in oncology

    2024  Volume 14, Page(s) 1345656

    Abstract: Background: Remimazolam is a new ultrashort-acting benzodiazepine for sedation and anesthesia. The effects of remimazolam and the mechanism by which it functions in cancer cells have not been determined. This research aimed to explore the mechanism of ... ...

    Abstract Background: Remimazolam is a new ultrashort-acting benzodiazepine for sedation and anesthesia. The effects of remimazolam and the mechanism by which it functions in cancer cells have not been determined. This research aimed to explore the mechanism of remimazolam action in colon cancer treatment, using bioinformatics analysis and
    Methods: Cell cycle progression, colony formation, self-renewal capacity, and apoptosis detection were performed in HCT8 cells treated with or without remimazolam. Transcriptome sequencing, Gene Ontology, Kyoto Encyclopedia of Genes and Genome, Protein-Protein Interaction, Gene Set Enrichment Analysis, Western blotting, and qPCR were performed to investigate the mechanism of action of remimazolam in HCT8 colon cancer cells.
    Results: Remimazolam promoted proliferation and cell-cycle progression of HCT8 cells. After remimazolam treatment, a total of 1,096 differentially expressed genes (DEGs) were identified: 673 genes were downregulated, and 423 genes were upregulated. The DEGs were enriched mainly in "DNA replication", "cell cycle", and "G1/S transition" related pathways. There were 15 DEGs verified by qPCR, and representative biomarkers were detected by Western Bloting. The remimazolam-mediated promotion of cell proliferation and cell cycle was reversed by G1T28, a CDK4/6 inhibitor.
    Conclusion: Remimazolam promoted cell-cycle progression and proliferation in HCT8 colon cancer cells, indicating that the long-term use of remimazolam has potential adverse effects in the anesthesia of patients with colon cancer.
    Language English
    Publishing date 2024-04-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1345656
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  6. Article: Revision and validation of the “Constitution in Chinese Medicine Questionnaire (Elderly Edition)” based on the Delphi process

    Song, Huirong / Bai, Minghua / Wang, Ji / Xia, Jing / Wang, Qi / Ni, Cheng

    Beijing University of Chinese Medicine Journal of traditional Chinese medical sciences. 2022 June 06,

    2022  

    Abstract: This study aimed to revise the Constitution in Chinese Medicine Questionnaire (Elderly Edition) (CCMQ-EE), as well as evaluate its reliability and validity. The objective was to provide a more accurate Chinese medicine constitution identification tool ... ...

    Abstract This study aimed to revise the Constitution in Chinese Medicine Questionnaire (Elderly Edition) (CCMQ-EE), as well as evaluate its reliability and validity. The objective was to provide a more accurate Chinese medicine constitution identification tool for geriatric health management and help further research on the relationship between geriatric diseases and constitution type, etc. The Delphi method and a cross-sectional survey of the elderly population were used. From April to October 2021, experts in different fields were invited to participate in the questionnaire, and items were revised through the experts’ ratings and feedback. From December 2021 to February 2022, the revised CCMQ-EE was validated in the elderly population. The coefficients of variation of rationality and importance scores decreased to less than 0.25 in the third round of Delphi. The Kendall coordination coefficients of rationality and importance in the third round were 0.15 and 0.17 (P = .031 and P = .007, respectively). The revised CCMQ-EE was established with 34 items. The factor loadings of subscales were between 0.39 and 0.92, and the fitting effects of other subscales were acceptable, except for the inherited special constitution. The Cronbach alpha and test–retest reliability coefficients of each subscale ranged from 0.65 to 0.83, and 0.66 to 0.96, respectively. The composite reliability and average variance extraction were between 0.66 and 0.84, and between 0.32 and 0.57, respectively. The reliability and validity of the revised CCMQ-EE were acceptable or satisfactory. The revised CCMQ-EE was developed through a three-round Delphi process and internal team discussion. After the verification in the elderly in Beijing area, its measurement performance was good. The updated questionnaire can probably replace the initial version to better promote health management and help healthy aging by identifying the constitution type of the elderly.
    Keywords Delphi method ; Oriental traditional medicine ; cross-sectional studies ; elderly ; variance ; China
    Language English
    Dates of publication 2022-0606
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ZDB-ID 2834228-8
    ISSN 2095-7548 ; 2589-0395
    ISSN 2095-7548 ; 2589-0395
    DOI 10.1016/j.jtcms.2022.06.006
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  7. Article: Amantadine Alleviates Postoperative Cognitive Dysfunction Possibly by Preserving Neurotrophic Factor Expression and Dendritic Arborization in the Hippocampus of Old Rodents.

    Zhong, Jing / Li, Jun / Ni, Cheng / Zuo, Zhiyi

    Frontiers in aging neuroscience

    2020  Volume 12, Page(s) 605330

    Abstract: Objectives: Amantadine has been shown to attenuate postoperative learning and memory dysfunction in young adult rats. However, postoperative cognitive dysfunction often occurs in elderly patients. We aimed to determine whether amantadine attenuated ... ...

    Abstract Objectives: Amantadine has been shown to attenuate postoperative learning and memory dysfunction in young adult rats. However, postoperative cognitive dysfunction often occurs in elderly patients. We aimed to determine whether amantadine attenuated postoperative learning and memory dysfunction and whether these effects were associated with improved dendritic arborization in old rodents.
    Methods: Eighteen-month old male C57BL/6J mice or Fischer 344 rats were subjected to right carotid artery exposure (surgery) under isoflurane anesthesia. This age represents an early old stage in rodents. Carotid artery exposure was used to simulate commonly performed carotid endarterectomy in elderly patients. Amantadine was injected intraperitoneally at 25 μg/g once a day for 3 days with the first dose at 15 min before surgery. The animals were tested by Barnes maze and fear conditioning starting one week after the surgery. Hippocampus was harvested for Western blotting and Golgi staining.
    Results: Surgery and anesthesia impaired the learning and memory in old mice and rats. Surgery reduced the expression of brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF), dendritic arborization and spine density in the hippocampus of old rats. These effects were attenuated by amantadine. The effects of amantadine were blocked by intracerebroventricular injection of anti-BDNF antibody or anti-GDNF antibody.
    Conclusion: Surgery and anesthesia impaired learning, memory and dendritic arborization in old rodents that are age relevant to postoperative cognitive dysfunction. These effects may be attenuated by amantadine via preserving the expression of neurotrophic factors.
    Language English
    Publishing date 2020-11-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2020.605330
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  8. Article ; Online: Mindfulness for those with COPD, Asthma, Lung Cancer and Lung Transplantation.

    Liang, Ni-Cheng / Von Visger, Tania / Devereaux, Asha

    American journal of respiratory and critical care medicine

    2020  

    Language English
    Publishing date 2020-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.2020C10
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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  9. Article ; Online: Mindfulness for Those with COPD, Asthma, Lung Cancer, and Lung Transplantation.

    Liang, Ni-Cheng / Visger, Tania Von / Devereaux, Asha

    American journal of respiratory and critical care medicine

    2020  Volume 202, Issue 4, Page(s) P11–P12

    MeSH term(s) Asthma/psychology ; Humans ; Lung Neoplasms/psychology ; Lung Transplantation/psychology ; Mindfulness ; Pulmonary Disease, Chronic Obstructive/psychology
    Language English
    Publishing date 2020-09-02
    Publishing country United States
    Document type Journal Article ; Patient Education Handout
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.2024P11
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  10. Article: Curcumin Ameliorates Cardiac Fibrosis by Regulating Macrophage-Fibroblast Crosstalk

    Zhao, Jing / Chen, Yongjian / Chen, Qiming / Hong, Tingting / Zhong, Zhiwei / He, Junhua / Ni, Cheng

    Frontiers in pharmacology

    2022  Volume 12, Page(s) 784041

    Abstract: Ethnopharmacological relevance: ...

    Abstract Ethnopharmacological relevance:
    Language English
    Publishing date 2022-01-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.784041
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