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  1. Article ; Online: Selective image segmentation driven by region, edge and saliency functions.

    Soomro, Shafiullah / Niaz, Asim / Soomro, Toufique Ahmed / Kim, Jin / Manzoor, Adnan / Choi, Kwang Nam

    PloS one

    2023  Volume 18, Issue 12, Page(s) e0294789

    Abstract: Present active contour methods often struggle with the segmentation of regions displaying variations in texture, color, or intensity a phenomenon referred to as inhomogeneities. These limitation impairs their ability to precisely distinguish and outline ... ...

    Abstract Present active contour methods often struggle with the segmentation of regions displaying variations in texture, color, or intensity a phenomenon referred to as inhomogeneities. These limitation impairs their ability to precisely distinguish and outline diverse components within an image. Further some of these methods employ intricate mathematical formulations for energy minimization. Such complexity introduces computational sluggishness, making these methods unsuitable for tasks requiring real-time processing or rapid segmentation. Moreover, these methods are susceptible to being trapped in energy configurations corresponding to local minimum points. Consequently, the segmentation process fails to converge to the desired outcome. Additionally, the efficacy of these methods diminishes when confronted with regions exhibiting weak or subtle boundaries. To address these limitations comprehensively, our proposed approach introduces a fresh paradigm for image segmentation through the synchronization of region-based, edge-based, and saliency-based segmentation techniques. Initially, we adapt an intensity edge term based on the zero crossing feature detector (ZCD), which is used to highlight significant edges of an image. Secondly, a saliency function is formulated to detect salient regions from an image. We have also included a globally tuned region based SPF (signed pressure force) term to move contour away and capture homogeneous regions. ZCD, saliency and global SPF are jointly incorporated with some scaled value for the level set evolution to develop an effective image segmentation model. In addition, proposed method is capable to perform selective object segmentation, which enables us to choose any single or multiple objects inside an image. Saliency function and ZCD detector are considered feature enhancement tools, which are used to get important features of an image, so this method has a solid capacity to segment nature images (homogeneous or inhomogeneous) precisely. Finally, the adaption of the Gaussian kernel removes the need of any penalization term for level set reinitialization. Experimental results will exhibit the efficiency of the proposed method.
    MeSH term(s) Algorithms ; Image Processing, Computer-Assisted/methods
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0294789
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 Crisis: the Effect of Anxiety and Fear on Rehabilitation Services.

    Bashir, Shahid / Niaz, Asim / Yoo, Woo-Kyoung

    Brain & NeuroRehabilitation

    2020  Volume 13, Issue 3, Page(s) e22

    Language English
    Publishing date 2020-11-13
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2383-9910
    ISSN (online) 2383-9910
    DOI 10.12786/bn.2020.13.e22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Self-initialized active contours for microscopic cell image segmentation.

    Niaz, Asim / Iqbal, Ehtesham / Akram, Farhan / Kim, Jin / Choi, Kwang Nam

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 14947

    Abstract: Level set models are suitable for processing topological changes in different regions of images while performing segmentation. Active contour models require an empirical setting for initial parameters, which is tedious for the end-user. This study ... ...

    Abstract Level set models are suitable for processing topological changes in different regions of images while performing segmentation. Active contour models require an empirical setting for initial parameters, which is tedious for the end-user. This study proposes an incremental level set model with the automatic initialization of contours based on local and global fitting energies that enable it to capture image regions containing intensity corruption or other light artifacts. The region-based area and the region-based length terms use signed pressure force (SPF) to strengthen the balloon force. SPF helps to achieve a smooth version of the gradient descent flow in terms of energy minimization. The proposed model is tested on multiple synthetic and real images. Our model has four advantages: first, there is no need for the end user to initialize the parameters; instead, the model is self-initialized. Second, it is more accurate than other methods. Third, it shows lower computational complexity. Fourth, it does not depend on the starting position of the contour. Finally, we evaluated the performance of our model on microscopic cell images (Coelho et al., in: 2009 IEEE international symposium on biomedical imaging: from nano to macro, IEEE, 2009) to confirm that its performance is superior to that of other state-of-the-art models.
    MeSH term(s) Algorithms ; Artifacts ; Image Processing, Computer-Assisted/methods ; Magnetic Resonance Imaging/methods
    Language English
    Publishing date 2022-09-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-18708-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Saliency-Driven Active Contour Model for Image Segmentation

    Iqbal, Ehtesham / Niaz, Asim / Memon, Asif Aziz / Asim, Usman / Choi, Kwang Nam

    2022  

    Abstract: Active contour models have achieved prominent success in the area of image segmentation, allowing complex objects to be segmented from the background for further analysis. Existing models can be divided into region-based active contour models and edge- ... ...

    Abstract Active contour models have achieved prominent success in the area of image segmentation, allowing complex objects to be segmented from the background for further analysis. Existing models can be divided into region-based active contour models and edge-based active contour models. However, both models use direct image data to achieve segmentation and face many challenging problems in terms of the initial contour position, noise sensitivity, local minima and inefficiency owing to the in-homogeneity of image intensities. The saliency map of an image changes the image representation, making it more visual and meaningful. In this study, we propose a novel model that uses the advantages of a saliency map with local image information (LIF) and overcomes the drawbacks of previous models. The proposed model is driven by a saliency map of an image and the local image information to enhance the progress of the active contour models. In this model, the saliency map of an image is first computed to find the saliency driven local fitting energy. Then, the saliency-driven local fitting energy is combined with the LIF model, resulting in a final novel energy functional. This final energy functional is formulated through a level set formulation, and regulation terms are added to evolve the contour more precisely across the object boundaries. The quality of the proposed method was verified on different synthetic images, real images and publicly available datasets, including medical images. The image segmentation results, and quantitative comparisons confirmed the contour initialization independence, noise insensitivity, and superior segmentation accuracy of the proposed model in comparison to the other segmentation models.
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Subject code 006
    Publishing date 2022-05-23
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: SRIS: Saliency-Based Region Detection and Image Segmentation of COVID-19 Infected Cases.

    Joshi, Aditi / Khan, Mohammed Saquib / Soomro, Shafiullah / Niaz, Asim / Han, Beom Seok / Choi, Kwang Nam

    IEEE access : practical innovations, open solutions

    2020  Volume 8, Page(s) 190487–190503

    Abstract: Noise or artifacts in an image, such as shadow artifacts, deteriorate the performance of state-of-the-art models for the segmentation of an image. In this study, a novel saliency-based region detection and image segmentation (SRIS) model is proposed to ... ...

    Abstract Noise or artifacts in an image, such as shadow artifacts, deteriorate the performance of state-of-the-art models for the segmentation of an image. In this study, a novel saliency-based region detection and image segmentation (SRIS) model is proposed to overcome the problem of image segmentation in the existence of noise and intensity inhomogeneity. Herein, a novel adaptive level-set evolution protocol based on the internal and external functions is designed to eliminate the initialization sensitivity, thereby making the proposed SRIS model robust to contour initialization. In the level-set energy function, an adaptive weight function is formulated to adaptively alter the intensities of the internal and external energy functions based on image information. In addition, the sign of energy function is modulated depending on the internal and external regions to eliminate the effects of noise in an image. Finally, the performance of the proposed SRIS model is illustrated on complex real and synthetic images and compared with that of the previously reported state-of-the-art models. Moreover, statistical analysis has been performed on coronavirus disease (COVID-19) computed tomography images and THUS10000 real image datasets to confirm the superior performance of the SRIS model from the viewpoint of both segmentation accuracy and time efficiency. Results suggest that SRIS is a promising approach for early screening of COVID-19.
    Language English
    Publishing date 2020-10-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2687964-5
    ISSN 2169-3536
    ISSN 2169-3536
    DOI 10.1109/ACCESS.2020.3032288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Segmentation of Intensity-Corrupted Medical Images Using Adaptive Weight-Based Hybrid Active Contours.

    Memon, Asif Aziz / Soomro, Shafiullah / Shahid, Muhammad Tanseef / Munir, Asad / Niaz, Asim / Choi, Kwang Nam

    Computational and mathematical methods in medicine

    2020  Volume 2020, Page(s) 6317415

    Abstract: Segmentation accuracy is an important criterion for evaluating the performance of segmentation techniques used to extract objects of interest from images, such as the active contour model. However, segmentation accuracy can be affected by image artifacts ...

    Abstract Segmentation accuracy is an important criterion for evaluating the performance of segmentation techniques used to extract objects of interest from images, such as the active contour model. However, segmentation accuracy can be affected by image artifacts such as intensity inhomogeneity, which makes it difficult to extract objects with inhomogeneous intensities. To address this issue, this paper proposes a hybrid region-based active contour model for the segmentation of inhomogeneous images. The proposed hybrid energy functional combines local and global intensity functions; an incorporated weight function is parameterized based on local image contrast. The inclusion of this weight function smoothens the contours at different intensity level boundaries, thereby yielding improved segmentation. The weight function suppresses false contour evolution and also regularizes object boundaries. Compared with other state-of-the-art methods, the proposed approach achieves superior results over synthetic and real images. Based on a quantitative analysis over the mini-MIAS and PH
    MeSH term(s) Computational Biology ; Computer Simulation ; Databases, Factual/statistics & numerical data ; Deep Learning ; Dermoscopy/statistics & numerical data ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Image Interpretation, Computer-Assisted/statistics & numerical data ; Mammography/statistics & numerical data ; Models, Statistical ; Pattern Recognition, Automated/methods ; Pattern Recognition, Automated/statistics & numerical data
    Language English
    Publishing date 2020-11-04
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2252430-7
    ISSN 1748-6718 ; 1748-670X ; 1027-3662
    ISSN (online) 1748-6718
    ISSN 1748-670X ; 1027-3662
    DOI 10.1155/2020/6317415
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Rehabilitation of a patient with spinal cord decompression sickness: First case report from Saudi Arabia.

    Ullah, Sami / Qureshi, Ahmad Zaheer / Kedowah, Kholoud / AlHargan, Afnan / Niaz, Asim

    Clinical case reports

    2019  Volume 7, Issue 11, Page(s) 2231–2234

    Abstract: This case brings attention to development of rehabilitation protocols for patients with decompression sickness (DCS). A lack of data regarding DCS renders the need of conducting multicenter studies to document the epidemiology and outcomes of spinal cord ...

    Abstract This case brings attention to development of rehabilitation protocols for patients with decompression sickness (DCS). A lack of data regarding DCS renders the need of conducting multicenter studies to document the epidemiology and outcomes of spinal cord DCS in Saudi Arabia.
    Language English
    Publishing date 2019-10-11
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.2453
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of transcranial magnetic stimulation on neurobiological changes in Alzheimer's disease (Review).

    Bashir, Shahid / Uzair, Mohammad / Abualait, Turki / Arshad, Muhammad / Khallaf, Roaa A / Niaz, Asim / Thani, Ziyad / Yoo, Woo-Kyoung / Túnez, Isaac / Demirtas-Tatlidede, Asli / Meo, Sultan Ayoub

    Molecular medicine reports

    2022  Volume 25, Issue 4

    Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and brain neuronal loss. A pioneering field of research in AD is brain stimulation via electromagnetic fields (EMFs), which may produce clinical benefits. ... ...

    Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and brain neuronal loss. A pioneering field of research in AD is brain stimulation via electromagnetic fields (EMFs), which may produce clinical benefits. Noninvasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS), have been developed to treat neurological and psychiatric disorders. The purpose of the present review is to identify neurobiological changes, including inflammatory, neurodegenerative, apoptotic, neuroprotective and genetic changes, which are associated with repetitive TMS (rTMS) treatment in patients with AD. Furthermore, it aims to evaluate the effect of TMS treatment in patients with AD and to identify the associated mechanisms. The present review highlights the changes in inflammatory and apoptotic mechanisms, mitochondrial enzymatic activities, and modulation of gene expression (microRNA expression profiles) associated with rTMS or sham procedures. At the molecular level, it has been suggested that EMFs generated by TMS may affect the cell redox status and amyloidogenic processes. TMS may also modulate gene expression by acting on both transcriptional and post‑transcriptional regulatory mechanisms. TMS may increase brain cortical excitability, induce specific potentiation phenomena, and promote synaptic plasticity and recovery of impaired functions; thus, it may re‑establish cognitive performance in patients with AD.
    MeSH term(s) Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Alzheimer Disease/therapy ; Animals ; Antioxidants ; Cognitive Dysfunction/therapy ; Executive Function ; Humans ; Memory ; Neuronal Plasticity ; Neuroprotective Agents/therapeutic use ; Neurotransmitter Agents/metabolism ; Transcranial Magnetic Stimulation/adverse effects ; Transcranial Magnetic Stimulation/methods
    Chemical Substances Antioxidants ; Neuroprotective Agents ; Neurotransmitter Agents
    Language English
    Publishing date 2022-02-04
    Publishing country Greece
    Document type Journal Article ; Review
    ZDB-ID 2469505-1
    ISSN 1791-3004 ; 1791-2997
    ISSN (online) 1791-3004
    ISSN 1791-2997
    DOI 10.3892/mmr.2022.12625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Functional outcomes in geriatric patients with spinal cord injuries at a tertiary care rehabilitation hospital in Saudi Arabia.

    Ullah, Sami / Qamar, Irfan / Qureshi, Ahmad Zaheer / Abu-Shaheen, Amani / Niaz, Asim

    Spinal cord series and cases

    2018  Volume 4, Page(s) 78

    Abstract: Study design: Retrospective study.: Objective: To identify demographic features, clinical characteristics, and complications associated with spinal cord injuries/disorders (SCI/D) among elderly individuals at a rehabilitation hospital and to measure ... ...

    Abstract Study design: Retrospective study.
    Objective: To identify demographic features, clinical characteristics, and complications associated with spinal cord injuries/disorders (SCI/D) among elderly individuals at a rehabilitation hospital and to measure the functional outcomes of rehabilitation.
    Setting: Rehabilitation hospital in King Fahad Medical City (KFMC), Riyadh, Saudi Arabia.
    Methods: The study was conducted in elderly individuals (aged ≥65 years) with SCI/D, admitted to an inpatient rehabilitation program between October 2014 and 2015. Demographic and clinical data were recorded along with functional independence measure (FIM) score at admission (FIMa) and discharge (FIMd). Data were descriptively analyzed. Association of non-metric and metric variables with complications was measured using
    Results: Twenty-four individuals with SCI/D (95.8% were male and retired) with mean (standard deviation, SD) age of 72.3 (6.3) years were included. The most common co-morbidities were hypertension (75.0%), and diabetes mellitus (58.3%). Degenerative cervical myelopathy (33.3%) was the most common cause of SCD. Of all, nine (37.5%) individuals had clinical complications (urinary tract infection(UTI); 8/9, surgical wound infection; 1/9). Mean (SD) hospitalization period during inpatient rehabilitation was 66.0 (13.9) days. Mean (SD) FIMa scores improved from 71.7 (17.3) to 85.3 (16.8) at discharge. Co-morbidities associated with complications were peripheral vascular disease, ischemic heart disease, and stroke.
    Conclusion: In Saudi Arabia, non-traumatic spinal etiologies are the most frequent cause of spinal cord dysfunction in the elderly. Male gender, hypertension, and diabetes mellitus were high-risk factors among the geriatric age group with SCI/D. Elderly individuals with SCI/D without complications can have a shorter hospitalization period and higher functional gains during rehabilitation.
    Language English
    Publishing date 2018-08-24
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2058-6124
    ISSN 2058-6124
    DOI 10.1038/s41394-018-0104-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comorbidities in Patients with COVID-19 and Their Impact on the Severity of the Disease

    Bashir, Shahid / Moneeba, Sadaf / Alghamdi, Alaa / Alghamdi, Fouad / Niaz, Asim / Anan, Hadeel / Kaleem, Imdad

    Journal of Health and Allied Sciences NU ; ISSN 2582-4287 2582-4953

    2020  

    Abstract: Abstract Infection with COVID-19 is associated with significant morbidity, especially in patients with chronic medical conditions. At least one-fifth of cases require supportive care in intensive care units, which have limited availability in most ... ...

    Abstract Abstract Infection with COVID-19 is associated with significant morbidity, especially in patients with chronic medical conditions. At least one-fifth of cases require supportive care in intensive care units, which have limited availability in most developing countries. A literature search was conducted on PubMed, Medline, Scopus, Embase, and Google Scholar to find articles published by May 7, 2020 on the role of comorbidities in patients with COVID-19 and the impact of comorbidities on the disease. This review highlighted that patients with comorbidities are more likely to experience severe disease than those with no other conditions; that is, comorbidities correlated with greater disease severity in patients with COVID-19. Proper screening of COVID-19 patients should include careful inquiries into their medical history; this will help healthcare providers identify patients who are more likely to develop serious disease or experience adverse outcomes. Better protection should also be given to patients with COVID-19 and comorbidities upon confirmation of the diagnosis. This literature review showed that the comorbidities most often associated with more severe cases of COVID-19 are hypertension, cardiovascular disease, and diabetes. Individuals with these comorbidities should adopt restrictive measures to prevent exposure to COVID-19, given their higher risk of severe disease.
    Keywords covid19
    Language English
    Publisher Georg Thieme Verlag KG
    Publishing country de
    Document type Article ; Online
    DOI 10.1055/s-0040-1718848
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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