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  1. Article ; Online: It Is Time to Overcome the "One-Size-Fits-All" Approach in Chronic Coronary Syndrome?

    Niccoli, Giampaolo / Gurgoglione, Filippo Luca

    The American journal of cardiology

    2024  

    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Editorial
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2024.03.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Myocardial infarction with nonobstructive coronary arteries in the era of COVID-19.

    Niccoli, Giampaolo / Gurgoglione, Filippo L

    Polish archives of internal medicine

    2023  Volume 133, Issue 5

    MeSH term(s) Humans ; COVID-19 ; MINOCA ; Myocardial Infarction
    Language English
    Publishing date 2023-05-23
    Publishing country Poland
    Document type Journal Article ; Comment
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.16505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Low-dose fibrinolysis during primary percutaneous intervention for preventing no-reflow: stepping back to move forward?

    Pelliccia, Francesco / Niccoli, Giampaolo

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2022  Volume 18, Issue 6, Page(s) 452–455

    MeSH term(s) Coronary Angiography ; Fibrinolysis ; Humans ; No-Reflow Phenomenon/prevention & control ; Percutaneous Coronary Intervention ; ST Elevation Myocardial Infarction/surgery
    Language English
    Publishing date 2022-08-05
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-D-22-00250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effects of Static Meditation Practice on Blood Lipid Levels: A Systematic Review and Meta-Analysis.

    Antonelli, Michele / Donelli, Davide / Gurgoglione, Filippo Luca / Lazzeroni, Davide / Halasz, Geza / Niccoli, Giampaolo

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 6

    Abstract: This review aims to delineate the potential impact of static meditation practice on cholesterol and triglyceride levels. PubMed, EMBASE, Web of Science, Cochrane Library, and Google Scholar were systematically screened up until December 2023 to identify ... ...

    Abstract This review aims to delineate the potential impact of static meditation practice on cholesterol and triglyceride levels. PubMed, EMBASE, Web of Science, Cochrane Library, and Google Scholar were systematically screened up until December 2023 to identify pertinent studies. After searching the scientific literature, 16 clinical studies (11 trials and 5 observational experiments) met the criteria for inclusion, involving a total of 1147 participants. In general, Ayurvedic-based meditation techniques were predominantly associated with lower total cholesterol levels, mindfulness-based techniques demonstrated benefits in both total cholesterol and triglyceride levels, and Eastern meditation techniques with spiritual origins were primarily linked to improved serum concentrations of HDL cholesterol. Study participants mostly engaged in meditation on a daily basis, often practicing it once or even twice a day, spanning a duration ranging from a few weeks to several months. The meta-analysis shows an association between meditation practice in healthy or sub-healthy adults and reduced cholesterol levels, with an average decrease of approximately -14 mg/dL (MD = -13.91 [-23.35; -4.47] mg/dL;
    Language English
    Publishing date 2024-03-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12060655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Another step towards "personalized prevention" of sudden cardiac death.

    Gurgoglione, Filippo Luca / Niccoli, Giampaolo

    International journal of cardiology

    2020  Volume 328, Page(s) 197–198

    MeSH term(s) Blood Pressure ; C-Reactive Protein ; Death, Sudden, Cardiac/epidemiology ; Death, Sudden, Cardiac/prevention & control ; Defibrillators, Implantable ; Humans ; Prospective Studies
    Chemical Substances C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2020-12-10
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2020.11.072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Myocardial infarction with non-obstructive coronary arteries: what is the prognosis?

    Niccoli, Giampaolo / Camici, Paolo G

    European heart journal supplements : journal of the European Society of Cardiology

    2020  Volume 22, Issue Suppl E, Page(s) E40–E45

    Abstract: Myocardial infarction in the absence of obstructive coronary stenosis (MINOCA) is a syndrome with several causes, characterized by clinical evidence of myocardial infarction and coronary angiographically normal or almost normal (stenosis ≤50%). MINOCAs ... ...

    Abstract Myocardial infarction in the absence of obstructive coronary stenosis (MINOCA) is a syndrome with several causes, characterized by clinical evidence of myocardial infarction and coronary angiographically normal or almost normal (stenosis ≤50%). MINOCAs represent about 10% of acute coronary syndromes. The causes of MINOCA are manifold and can be classified on the basis of the mechanism in epicardial (unstable plaque not manifested by angiography, epicardial spasm and coronary dissection) or microvascular. The latter in turn can be divided into intrinsic (microvascular spasm, Takotsubo syndrome and coronary embolization) and extrinsic (myocarditis). In the former, the dysfunctional microcirculation causes myocardial necrosis due to reduction of the lumen due to vasoconstriction and / or obstruction, while in the latter, the compression of the lumen occurs ab extrinsic due to myocardial edema. Note that the prognosis of MINOCA is extremely variable and depends on the underlying cause with high risk clinical subsets. A correct diagnostic procedure includes first level tests (clinical / anamnestic examination, ECG, myocardial necrosis enzyme dosage, trans-thoracic echocardiogram, coronary angiography, ventriculogram) and second level tests (intracoronary imaging, coronary vasomotor test, cardiac nuclear magnetic resonance and trans-esophageal or contrast ultrasound). Through this process, it is possible to identify the cause of MINOCA, fundamental for targeting therapy on the disease mechanism, thus constituting a typical example of precision medicine.
    Language English
    Publishing date 2020-03-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1463769-8
    ISSN 1554-2815 ; 1520-765X
    ISSN (online) 1554-2815
    ISSN 1520-765X
    DOI 10.1093/eurheartj/suaa057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Exposome in ischaemic heart disease: beyond traditional risk factors.

    Montone, Rocco A / Camilli, Massimiliano / Calvieri, Camilla / Magnani, Giulia / Bonanni, Alice / Bhatt, Deepak L / Rajagopalan, Sanjay / Crea, Filippo / Niccoli, Giampaolo

    European heart journal

    2024  Volume 45, Issue 6, Page(s) 419–438

    Abstract: Ischaemic heart disease represents the leading cause of morbidity and mortality, typically induced by the detrimental effects of risk factors on the cardiovascular system. Although preventive interventions tackling conventional risk factors have helped ... ...

    Abstract Ischaemic heart disease represents the leading cause of morbidity and mortality, typically induced by the detrimental effects of risk factors on the cardiovascular system. Although preventive interventions tackling conventional risk factors have helped to reduce the incidence of ischaemic heart disease, it remains a major cause of death worldwide. Thus, attention is now shifting to non-traditional risk factors in the built, natural, and social environments that collectively contribute substantially to the disease burden and perpetuate residual risk. Of importance, these complex factors interact non-linearly and in unpredictable ways to often enhance the detrimental effects attributable to a single or collection of these factors. For this reason, a new paradigm called the 'exposome' has recently been introduced by epidemiologists in order to define the totality of exposure to these new risk factors. The purpose of this review is to outline how these emerging risk factors may interact and contribute to the occurrence of ischaemic heart disease, with a particular attention on the impact of long-term exposure to different environmental pollutants, socioeconomic and psychological factors, along with infectious diseases such as influenza and COVID-19. Moreover, potential mitigation strategies for both individuals and communities will be discussed.
    MeSH term(s) Humans ; Exposome ; Risk Factors ; Myocardial Ischemia/epidemiology ; Myocardial Ischemia/etiology ; Coronary Artery Disease ; Morbidity ; Environmental Exposure/adverse effects
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehae001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Intracoronary Imaging of Coronary Atherosclerotic Plaque: From Assessment of Pathophysiological Mechanisms to Therapeutic Implication.

    Gurgoglione, Filippo Luca / Denegri, Andrea / Russo, Michele / Calvieri, Camilla / Benatti, Giorgio / Niccoli, Giampaolo

    International journal of molecular sciences

    2023  Volume 24, Issue 6

    Abstract: Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality worldwide. Several cardiovascular risk factors are implicated in atherosclerotic plaque promotion and progression and are responsible for the clinical manifestations ... ...

    Abstract Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality worldwide. Several cardiovascular risk factors are implicated in atherosclerotic plaque promotion and progression and are responsible for the clinical manifestations of coronary artery disease (CAD), ranging from chronic to acute coronary syndromes and sudden coronary death. The advent of intravascular imaging (IVI), including intravascular ultrasound, optical coherence tomography and near-infrared diffuse reflectance spectroscopy has significantly improved the comprehension of CAD pathophysiology and has strengthened the prognostic relevance of coronary plaque morphology assessment. Indeed, several atherosclerotic plaque phenotype and mechanisms of plaque destabilization have been recognized with different natural history and prognosis. Finally, IVI demonstrated benefits of secondary prevention therapies, such as lipid-lowering and anti-inflammatory agents. The purpose of this review is to shed light on the principles and properties of available IVI modalities along with their prognostic significance.
    MeSH term(s) Humans ; Plaque, Atherosclerotic/diagnostic imaging ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/therapy ; Spectroscopy, Near-Infrared/methods ; Tomography, Optical Coherence/methods ; Acute Coronary Syndrome ; Coronary Vessels/diagnostic imaging ; Ultrasonography, Interventional/methods
    Language English
    Publishing date 2023-03-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24065155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Timing and modality of complete revascularization in patients presenting with ST-segment elevation myocardial infarction and multivessel coronary artery disease.

    Benatti, Giorgio / Gragnano, Felice / Vignali, Luigi / Calabrò, Paolo / Gurgoglione, Filippo Luca / Niccoli, Giampaolo

    International journal of cardiology

    2023  Volume 380, Page(s) 6–11

    Abstract: Approximately half of the patients presenting with ST-segment elevation myocardial infarction have also significant atherosclerotic disease affecting coronary segments other than the infarct-related artery. Optimal management of residual lesions in this ... ...

    Abstract Approximately half of the patients presenting with ST-segment elevation myocardial infarction have also significant atherosclerotic disease affecting coronary segments other than the infarct-related artery. Optimal management of residual lesions in this clinical setting has been a topic of intense research in the last decade. On the one hand, a large body of evidence has consistently shown the benefit of complete revascularization for the reduction of adverse cardiovascular outcomes. On the other hand, some crucial aspects such as the optimal timing or the best strategy of the complete treatment approach remain a matter of controversy. In this review, we aim to provide a thorough critical appraisal of the available literature regarding this topic, by discussing areas of relative certainty, gaps in the knowledge, approach to specific clinical subsets and future research directions.
    MeSH term(s) Humans ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/surgery ; Myocardial Revascularization ; Percutaneous Coronary Intervention/adverse effects ; ST Elevation Myocardial Infarction/diagnosis ; ST Elevation Myocardial Infarction/surgery ; ST Elevation Myocardial Infarction/etiology ; Vascular Surgical Procedures ; Treatment Outcome
    Language English
    Publishing date 2023-03-11
    Publishing country Netherlands
    Document type Journal Article ; Review ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2023.03.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Ginsenoside Re: Are we Close to a Safer Antiplatelet Therapy?

    Betti, Matteo / Bernardi, Marco / Niccoli, Giampaolo / Biondi-Zoccai, Giuseppe / Spadafora, Luigi

    Journal of cardiovascular pharmacology

    2023  Volume 82, Issue 1, Page(s) 37–39

    MeSH term(s) Platelet Aggregation Inhibitors/adverse effects ; Ginsenosides/adverse effects
    Chemical Substances ginsenoside Re (46F3R0BL3I) ; Platelet Aggregation Inhibitors ; Ginsenosides
    Language English
    Publishing date 2023-07-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391970-5
    ISSN 1533-4023 ; 0160-2446
    ISSN (online) 1533-4023
    ISSN 0160-2446
    DOI 10.1097/FJC.0000000000001431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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