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  1. AU="Nicholas Tadros"
  2. AU="Ntelkis, Nikolaos"
  3. AU=Pitrou Isabelle
  4. AU="Ouwehand, Willem"
  5. AU=Glover Natasha M.
  6. AU=Guo Zhinian
  7. AU="Alison M. Lee"
  8. AU="Walcher, Felix"
  9. AU=Marupudi Neena I.
  10. AU="Earp, Karly M"
  11. AU="Zeng, Hui Hui"
  12. AU="Marco Pallecchi"
  13. AU=Marcus Adam I
  14. AU="Martin, Phillip"
  15. AU=Ouyang Yi-Bing
  16. AU="Tam, Patrick Chung Kay"
  17. AU="Patrick R. H. Steinmetz"
  18. AU="Odierna, Francesco"
  19. AU="Monteiro, Valter" AU="Monteiro, Valter"
  20. AU=Konkel Alex
  21. AU="Alnakib, Yasir"
  22. AU=Tallerico Rossana
  23. AU=Scherer Kai
  24. AU="Cao, Guiyun"
  25. AU="Zarrouki, Youssef"
  26. AU="Abayomi, Akin"
  27. AU=Kpatcha Tchazou
  28. AU=Glaeser Robert M
  29. AU="Mioara Cristea"
  30. AU="Turiegano, Enrique"
  31. AU="Russcher, H"
  32. AU="Lim, Kean-Jin"
  33. AU="Spurek, Monika"
  34. AU="Giulia A. Zamboni"

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  1. Artikel ; Online: Role of Cytocentrifugation Combined with Nuclear Fast Picroindigocarmine Staining in Detecting Cryptozoospermia in Men Diagnosed with Azoospermia

    Rakesh Kumar Sharma / Sajal Gupta / Ashok Agarwal / Renata Finelli / Shinnosuke Kuroda / Ramadan Saleh / Florence Boitrelle / Parviz Kavoussi / Murat Gül / Nicholas Tadros / Edmund Ko / Ala’a Farkouh / Ralf Henkel / Mohamed Arafa / Amarnath Rambhatla / Rupin Shah

    The World Journal of Men's Health, Vol 40, Iss 4, Pp 627-

    2022  Band 635

    Abstract: Purpose: Azoospermia is defined as the absence of spermatozoa in the pellet of a centrifuged semen sample. In fact, when a basic semen analysis fails to detect sperm in the ejaculate, there is still the possibility of detecting rare sperm after ... ...

    Abstract Purpose: Azoospermia is defined as the absence of spermatozoa in the pellet of a centrifuged semen sample. In fact, when a basic semen analysis fails to detect sperm in the ejaculate, there is still the possibility of detecting rare sperm after centrifugation of the sample and examination of the pellet. In this study, we assessed the role of Cytospin centrifugation in combination with the nuclear fast picroindigocarmine (NF-PIC) staining in identifying sperm in azoospermic samples. Materials and Methods: Semen samples of 251 men diagnosed as having azoospermia after standard examination were further analyzed by Cytospin centrifugation in combination with NF-PIC staining. Results: Sperm were detected in 60 men (23.9%), thus changing their diagnosis to cryptozoospermia. Conclusions: By identifying sperm in the semen of men who were thought to have total azoospermia, the Cytospin NF-PIC test can alter the diagnosis and further treatment of these men.
    Schlagwörter azoospermia ; centrifugation ; male infertility ; semen ; staining and labeling ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2022-10-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
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  2. Artikel ; Online: Utility of Antioxidants in the Treatment of Male Infertility

    Ashok Agarwal / Kristian Leisegang / Ahmad Majzoub / Ralf Henkel / Renata Finelli / Manesh Kumar Panner Selvam / Nicholas Tadros / Neel Parekh / Edmund Y. Ko / Chak-Lam Cho / Mohamed Arafa / Marco G. Alves / Pedro Fontes Oliveira / Juan G. Alvarez / Rupin Shah

    The World Journal of Men's Health, Vol 39, Iss 2, Pp 233-

    Clinical Guidelines Based on a Systematic Review and Analysis of Evidence

    2021  Band 290

    Abstract: It is widely accepted that oxidative stress plays an important role in the pathophysiology of male infertility and that antioxidants could have a significant role in the treatment of male infertility. The main objectives of this study are: 1) to ... ...

    Abstract It is widely accepted that oxidative stress plays an important role in the pathophysiology of male infertility and that antioxidants could have a significant role in the treatment of male infertility. The main objectives of this study are: 1) to systematically review the current evidence for the utility of antioxidants in the treatment of male infertility; and 2) propose evidence-based clinical guidelines for the use of antioxidants in the treatment of male infertility. A systematic review of the available clinical evidence was performed, with articles published on Scopus being manually screened. Data extracted included the type of antioxidant used, the clinical conditions under investigation, the evaluation of semen parameters and reproductive outcomes. The adherence to the Cambridge Quality Checklist, Cochrane Risk of Bias for randomized controlled trials (RCTs), CONSORT guidelines and JADAD score were analyzed for each included study. Further, we provided a Strength Weakness Opportunity Threat (SWOT) analysis to analyze the current and future value of antioxidants in male infertility. Of the 1,978 articles identified, 97 articles were included in the study. Of these, 52 (53.6%) were uncontrolled (open label), 12 (12.4%) unblinded RCTs, and 33 (34.0%) blinded RCTs, whereas 44 (45.4%) articles tested individual antioxidants, 31 (32.0%) a combination of several products in variable dosages, and 22 (22.6%) registered antioxidant products. Based on the published evidence, we 1) critically examined the necessity of additional double-blind, randomized, placebo-controlled trials, and 2) proposed updated evidence-based clinical guidelines for antioxidant therapy in male infertility. The current systematic review on antioxidants and male infertility clearly shows that antioxidant supplementation improves semen parameters. In addition, it provides the indications for antioxidant treatment in specific clinical conditions, including varicocele, unexplained and idiopathic male infertility, as well as in cases of altered ...
    Schlagwörter antioxidants ; oxidative stress ; practice guideline ; semen analysis ; sperm maturation ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2021-04-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Sperm DNA Fragmentation

    Ashok Agarwal / Ahmad Majzoub / Saradha Baskaran / Manesh Kumar Panner Selvam / Chak Lam Cho / Ralf Henkel / Renata Finelli / Kristian Leisegang / Pallav Sengupta / Catalina Barbarosie / Neel Parekh / Marco G. Alves / Edmund Ko / Mohamed Arafa / Nicholas Tadros / Ranjith Ramasamy / Parviz Kavoussi / Rafael Ambar / Manish Kuchakulla /
    Kathy Amy Robert / Concetta Iovine / Damayanthi Durairajanayagam / Sunil Jindal / Rupin Shah

    The World Journal of Men's Health, Vol 38, Iss 4, Pp 412-

    A New Guideline for Clinicians

    2020  Band 471

    Abstract: Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic ... ...

    Abstract Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic content. Testicular (defective maturation and abortive apoptosis) and post-testicular (oxidative stress) mechanisms are implicated in the etiology of sperm DNA fragmentation (SDF), which affects both natural and assisted reproduction. Several clinical and environmental factors are known to negatively impact sperm DNA integrity. An increasing number of reports emphasizes the direct relationship between sperm DNA damage and male infertility. Currently, several assays are available to assess sperm DNA damage, however, routine assessment of SDF in clinical practice is not recommended by professional organizations. This article provides an overview of SDF types, origin and comparative analysis of various SDF assays while primarily focusing on the clinical indications of SDF testing. Importantly, we report four clinical cases where SDF testing had played a significant role in improving fertility outcome. In light of these clinical case reports and recent scientific evidence, this review provides expert recommendations on SDF testing and examines the advantages and drawbacks of the clinical utility of SDF testing using Strength-Weaknesses-Opportunities-Threats (SWOT) analysis.
    Schlagwörter assisted reproductive techniques outcome ; clinical guidelines ; infertility ; male ; oxidative stress ; sperm dna fragmentation ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2020-10-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Sperm Vitality and Necrozoospermia

    Ashok Agarwal / Rakesh K. Sharma / Sajal Gupta / Florence Boitrelle / Renata Finelli / Neel Parekh / Damayanthi Durairajanayagam / Ramadan Saleh / Mohamed Arafa / Chak Lam Cho / Ala’a Farkouh / Amarnath Rambhatla / Ralf Henkel / Paraskevi Vogiatzi / Nicholas Tadros / Parviz Kavoussi / Edmund Ko / Kristian Leisegang / Hussein Kandil /
    Ayad Palani / Gianmaria Salvio / Taymour Mostafa / Osvaldo Rajmil / Saleem Ali Banihani / Samantha Schon / Tan V. Le / Ponco Birowo / Gökhan Çeker / Juan Alvarez / Juan Manuel Corral Molina / Christopher C.K. Ho / Aldo E. Calogero / Kareim Khalafalla / Mesut Berkan Duran / Shinnosuke Kuroda / Giovanni M. Colpi / Armand Zini / Christina Anagnostopoulou / Edoardo Pescatori / Eric Chung / Ettore Caroppo / Fotios Dimitriadis / Germar-Michael Pinggera / Gian Maria Busetto / Giancarlo Balercia / Haitham Elbardisi / Hisanori Taniguchi / Hyun Jun Park / Israel Maldonado Rosas / Jean de la Rosette

    The World Journal of Men's Health, Vol 40, Iss 2, Pp 228-

    Diagnosis, Management, and Results of a Global Survey of Clinical Practice

    2022  Band 242

    Abstract: Sperm vitality testing is a basic semen examination that has been described in the World Health Organization (WHO) Laboratory Manual for the Examination and Processing of Human Semen from its primary edition, 40 years ago. Several methods can be used to ... ...

    Abstract Sperm vitality testing is a basic semen examination that has been described in the World Health Organization (WHO) Laboratory Manual for the Examination and Processing of Human Semen from its primary edition, 40 years ago. Several methods can be used to test sperm vitality, such as the eosin-nigrosin (E-N) stain or the hypoosmotic swelling (HOS) test. In the 6th (2021) edition of the WHO Laboratory Manual, sperm vitality assessment is mainly recommended if the total motility is less than 40%. Hence, a motile spermatozoon is considered alive, however, in certain conditions an immotile spermatozoon can also be alive. Therefore, the differentiation between asthenozoospermia (pathological decrease in sperm motility) and necrozoospermia (pathological decrease in sperm vitality) is important in directing further investigation and management of infertile patients. The causes leading to necrozoospermia are diverse and can either be local or general, testicular or extra-testicular. The andrological management of necrozoospermia depends on its etiology. However, there is no standardized treatment available presently and practice varies among clinicians. In this study, we report the results of a global survey to understand current practices regarding the physician order of sperm vitality tests as well as the management practices for necrozoospermia. Laboratory and clinical scenarios are presented to guide the reader in the management of necrozoospermia with the overall objective of establishing a benchmark ranging from the diagnosis of necrozoospermia by sperm vitality testing to its clinical management.
    Schlagwörter asthenozoospermia ; eosine yellowish-(ys) ; infertility ; nigrosin ; spermatozoa ; vitality ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2022-04-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Antisperm Antibody Testing

    Sajal Gupta / Rakesh Sharma / Ashok Agarwal / Florence Boitrelle / Renata Finelli / Ala’a Farkouh / Ramadan Saleh / Taha Abo-Almagd Abdel-Meguid / Murat Gül / Birute Zilaitiene / Edmund Ko / Amarnath Rambhatla / Armand Zini / Kristian Leisegang / Shinnosuke Kuroda / Ralf Henkel / Rossella Cannarella / Ayad Palani / Chak-Lam Cho /
    Christopher C.K. Ho / Daniel Suslik Zylbersztejn / Edoardo Pescatori / Eric Chung / Fotios Dimitriadis / Germar-Michael Pinggera / Gian Maria Busetto / Giancarlo Balercia / Gianmaria Salvio / Giovanni M. Colpi / Gökhan Çeker / Hisanori Taniguchi / Hussein Kandil / Hyun Jun Park / Israel Maldonado Rosas / Jean de la Rosette / Joao Paulo Greco Cardoso / Jonathan Ramsay / Juan Alvarez / Juan Manuel Corral Molina / Kareim Khalafalla / Kasonde Bowa / Kelton Tremellen / Evangelini Evgeni / Lucia Rocco / Marcelo Gabriel Rodriguez Peña / Marjan Sabbaghian / Marlon Martinez / Mohamed Arafa / Mohamed S. Al-Marhoon / Nicholas Tadros

    The World Journal of Men's Health, Vol 40, Iss 3, Pp 380-

    A Comprehensive Review of Its Role in the Management of Immunological Male Infertility and Results of a Global Survey of Clinical Practices

    2022  Band 398

    Abstract: Antisperm antibodies (ASA), as a cause of male infertility, have been detected in infertile males as early as 1954. Multiple causes of ASA production have been identified, and they are due to an abnormal exposure of mature germ cells to the im-mune ... ...

    Abstract Antisperm antibodies (ASA), as a cause of male infertility, have been detected in infertile males as early as 1954. Multiple causes of ASA production have been identified, and they are due to an abnormal exposure of mature germ cells to the im-mune system. ASA testing (with mixed anti-globulin reaction, and immunobead binding test) was described in the WHO manual 5th edition and is most recently listed among the extended semen tests in the WHO manual 6th edition. The relation-ship between ASA and infertility is somewhat complex. The presence of sperm agglutination, while insufficient to diagnose immunological infertility, may indicate the presence of ASA. However, ASA can also be present in the absence of any sperm agglutination. The andrological management of ASA depends on the etiology and individual practices of clinicians. In this ar-ticle, we provide a comprehensive review of the causes of ASA production, its role in immunological male infertility, clinical indications of ASA testing, and the available therapeutic options. We also provide the details of laboratory procedures for as-sessment of ASA together with important measures for quality control. Additionally, laboratory and clinical scenarios are pre-sented to guide the reader in the management of ASA and immunological male infertility. Furthermore, we report the results of a recent worldwide survey, conducted to gather information about clinical practices in the management of immunological male infertility.
    Schlagwörter antibodies ; infertility ; male ; spermatozoa ; sperm agglutination ; survey ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2022-07-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: A Comprehensive Guide to Sperm Recovery in Infertile Men with Retrograde Ejaculation

    Sajal Gupta / Rakesh Sharma / Ashok Agarwal / Neel Parekh / Renata Finelli / Rupin Shah / Hussein Kandil / Ramadan Saleh / Mohamed Arafa / Edmund Ko / Mara Simopoulou / Armand Zini / Osvaldo Rajmil / Parviz Kavoussi / Keerti Singh / Rafael F. Ambar / Haitham Elbardisi / Pallav Sengupta / Marlon Martinez /
    Florence Boitrelle / Marco G. Alves / Kareim Khalafalla / Shubhadeep Roychoudhury / Gian Maria Busetto / Jaime Gosalvez / Nicholas Tadros / Ayad Palani / Marcelo Gabriel Rodriguez / Christina Anagnostopoulou / Sava Micic / Lucia Rocco / Taymour Mostafa / Juan G. Alvarez / Sunil Jindal / Hassan Sallam / Israel Maldonado Rosas / Sheena E. M. Lewis / Sami AlSaid / Mesut Altan / Hyun Jun Park / Jonathan Ramsay / Sijo Parekattil / Marjan Sabbaghian / Kelton Tremellen / Paraskevi Vogiatzi / Mohammad Ali Sadighi Gilani / Donald P. Evenson / Giovanni M. Colpi

    The World Journal of Men's Health, Vol 40, Iss 2, Pp 208-

    2022  Band 216

    Abstract: Retrograde ejaculation (RE) is a condition defined as the backward flow of the semen during ejaculation, and when present can result in male infertility. RE may be partial or complete, resulting in either low seminal volume or complete absence of the ... ...

    Abstract Retrograde ejaculation (RE) is a condition defined as the backward flow of the semen during ejaculation, and when present can result in male infertility. RE may be partial or complete, resulting in either low seminal volume or complete absence of the ejaculate (dry ejaculate). RE can result from anatomic, neurological or pharmacological conditions. The treatment approaches outlined are determined by the cause. Alkalinizing urinary pH with oral medications or by adding sperm wash media into the bladder prior to ejaculation may preserve the viability of the sperm. This article provides a step-by-step guide to diagnose RE and the optimal techniques to retrieve sperm.
    Schlagwörter ejaculation ; male infertility ; sperm count ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Sprache Englisch
    Erscheinungsdatum 2022-04-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Relevance of Leukocytospermia and Semen Culture and Its True Place in Diagnosing and Treating Male Infertility

    Rakesh Sharma / Sajal Gupta / Ashok Agarwal / Ralf Henkel / Renata Finelli / Neel Parekh / Ramadan Saleh / Mohamed Arafa / Edmund Ko / Armand Zini / Nicholas Tadros / Rupin Shah / Rafael F. Ambar / Haitham Elbardisi / Pallav Sengupta / Marlon Martinez / Florence Boitrelle / Mara Simopoulou / Paraskevi Vogiatzi /
    Jaime Gosalvez / Parviz Kavoussi / Hussein Kandil / Ayad Palani / Marcelo Rodriguez Peña / Osvaldo Rajmil / Gian Maria Busetto / Christina Anagnostopoulou / Sava Micic / Marco G. Alves / Lucia Rocco / Taymour Mostafa / Juan G. Alvarez / Sunil Jindal / Hassan N. Sallam / Israel Maldonado Rosas / Sheena E.M. Lewis / Sami AlSaid / Mesut Altan / Hyun Jun Park / Jonathan Ramsay / Sijo Parekattil / Marjan Sabbaghian / Kelton Tremellen / Kareim Khalafalla / Damayanthi Durairajanayagam / Giovanni M. Colpi

    The World Journal of Men's Health, Vol 40, Iss 2, Pp 191-

    2022  Band 207

    Abstract: The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive leukocytes at a concentration >1×106/mL of semen. Granular leukocytes when activated are capable of generating high levels of reactive ... ...

    Abstract The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive leukocytes at a concentration >1×106/mL of semen. Granular leukocytes when activated are capable of generating high levels of reactive oxygen species in semen resulting in oxidative stress. Oxidative stress has been correlated with poor sperm quality, increased level of sperm DNA fragmentation and low fertility potential. The presence of leukocytes and pathogens in the semen may be a sign of infection and/or localized inflammatory response in the male genital tract and the accessory glands. Common uro-pathogens including Chlamydia trachomatis, Ureaplasma urealyticum, Neisseria gonorrhoeae, Mycoplasma hominis, and Escherichia coli can cause epididymitis, epididymo-orchitis, or prostatitis. The relationship between leukocytospermia and infection is unclear. Therefore, we describe the pathogens responsible for male genital tract infections and their association with leukocytospermia. The review also examines the diagnostic tests available to identify seminal leukocytes. The role of leukocytospermia in male infertility and its management is also discussed.
    Schlagwörter culture ; endtz ; infections ; inflammation ; leukocytes ; spermatozoa ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2022-04-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Post-Vasectomy Semen Analysis

    Ashok Agarwal / Sajal Gupta / Rakesh K. Sharma / Renata Finell / Shinnosuke Kuroda / Sarah C. Vij / Florence Boitrelle / Parviz Kavoussi / Amarnath Rambhata / Ramadan Saleh / Eric Chung / Taymour Mostafa / Armand Zini / Edmund Ko / Neel Parekh / Marlon Martinez / Mohamed Arafa / Nicholas Tadros / Jean de la Rosette /
    Tan V. Le / Osvaldo Rajmil / Hussein Kandil / Gideon Blecher / Giovanni Liguori / Ettore Caroppo / Christopher C.K. Ho / Andrew Altman / Petar Bajic / David Goldfarb / Bradley Gill / Daniel Suslik Zylbersztejn / Juan Manuel Corral Molina / Marcello M. Gava / Joao Paulo Greco Cardoso / Raghavender Kosgi / Gökhan Çeker / Birute Zilaitiene / Edoardo Pescatori / Edson Borges Jr / Gede Wirya Kusuma Duarsa / Germar-Michael Pinggera / Gian Maria Busetto / Giancarlo Balercia / Giorgio Franco / Gökhan Çalik / Hassan N. Sallam / Hyun Jun Park / Jonathan Ramsay / Juan Alvarez / Kareim Khalafalla

    The World Journal of Men's Health, Vol 40, Iss 3, Pp 425-

    Optimizing Laboratory Procedures and Test Interpretation through a Clinical Audit and Global Survey of Practices

    2022  Band 441

    Abstract: Purpose:Purpose: The success of vasectomy is determined by the outcome of a post-vasectomy semen analysis (PVSA). This article describes a step-by-step procedure to perform PVSA accurately, report data from patients who underwent post vasectomy se-men ... ...

    Abstract Purpose:Purpose: The success of vasectomy is determined by the outcome of a post-vasectomy semen analysis (PVSA). This article describes a step-by-step procedure to perform PVSA accurately, report data from patients who underwent post vasectomy se-men analysis between 2015 and 2021 experience, along with results from an international online survey on clinical practice. Materials and Methods:Materials and Methods: We present a detailed step-by-step protocol for performing and interpretating PVSA testing, along with recommendations for proficiency testing, competency assessment for performing PVSA, and clinical and laboratory sce-narios. Moreover, we conducted an analysis of 1,114 PVSA performed at the Cleveland Clinic’s Andrology Laboratory and an online survey to understand clinician responses to the PVSA results in various countries. Results:Results: Results from our clinical experience showed that 92.1% of patients passed PVSA, with 7.9% being further tested. A total of 78 experts from 19 countries participated in the survey, and the majority reported to use time from vasectomy rather than the number of ejaculations as criterion to request PVSA. A high percentage of responders reported permitting unpro-tected intercourse only if PVSA samples show azoospermia while, in the presence of few non-motile sperm, the majority of responders suggested using alternative contraception, followed by another PVSA. In the presence of motile sperm, the major-ity of participants asked for further PVSA testing. Repeat vasectomy was mainly recommended if motile sperm were observed after multiple PVSA’s. A large percentage reported to recommend a second PVSA due to the possibility of legal actions. Conclusions:Conclusions: Our results highlighted varying clinical practices around the globe, with controversy over the significance of non-motile sperm in the PVSA sample. Our data suggest that less stringent AUA guidelines would help improve test compli-ance. A large longitudinal multi-center study would clarify various doubts related ...
    Schlagwörter male contraception ; semen ; sperm ; survey ; vasectomy ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 310
    Sprache Englisch
    Erscheinungsdatum 2022-07-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility

    Ashok Agarwal / Renata Finelli / Manesh Kumar Panner Selvam / Kristian Leisegang / Ahmad Majzoub / Nicholas Tadros / Edmund Ko / Neel Parekh / Ralf Henkel / Damayanthi Durairajanayagam / Giovanni M. Colpi / Chak-Lam Cho / Hassan N. Sallam / Hyun Jun Park / Ramadan Saleh / Sava Micic / Rafael F. Ambar / Armand Zini / Kelton Tremellen /
    Juan G. Alvarez / Ayad Palani / Mohamed Arafa / Marcello M. Gava / Sunil Jindal / Edouard Amar / Zsolt Kopa / Mohammad-Reza Moein / Gian Maria Busetto / Pallav Sengupta / Parviz Kavoussi / Israel Maldonado / Jamal Fikri / Edson Borges Jr. / Marlon Martinez / Djordje Bojovic / Osvaldo Rajmil / Kaan Aydos / Sijo Parekattil / Joel L. Marmar / Omar Sefrioui / Andreas Jungwirth / Marcelo Gabriel Rodriguez Peña / Emerson B. Cordts / Haitham Elbardisi / Taymour Mostafa / Marjan Sabbaghian / Mohammad Ali Sadighi Gilani / Yoshiharu Morimoto / Marco G. Alves / Aleksandra Spasic

    The World Journal of Men's Health, Vol 39, Iss 3, Pp 470-

    2021  Band 488

    Abstract: Purpose: The use of antioxidants is common practice in the management of infertile patients. However, there are no estab-lished guidelines by professional societies on antioxidant use for male infertility. Materials and Materials and Methods:Methods: ... ...

    Abstract Purpose: The use of antioxidants is common practice in the management of infertile patients. However, there are no estab-lished guidelines by professional societies on antioxidant use for male infertility. Materials and Materials and Methods:Methods: Using an online survey, this study aimed to evaluate the practice pattern of reproductive specialists to determine the clinical utility of oxidative stress (OS) testing and antioxidant prescriptions to treat male infertility. Results:Results: Responses from 1,327 participants representing 6 continents, showed the largest participant representation being from Asia (46.8%). The majority of participants were attending physicians (59.6%), with 61.3% having more than 10 years of experience in the field of male infertility. Approximately two-thirds of clinicians (65.7%) participated in this survey did not order any diagnostic tests for OS. Sperm DNA fragmentation was the most common infertility test beyond a semen analysis that was prescribed to study oxidative stress-related dysfunctions (53.4%). OS was mainly tested in the presence of lifestyle risk factors (24.6%) or sperm abnormalities (16.3%). Interestingly, antioxidants were prescribed by 85.6% of clinicians, for a duration of 3 (43.7%) or 3?? months (38.6%). A large variety of antioxidants and dietary supplements were prescribed, and scientific evidence were mostly considered to be modest to support their clinical use. Results were not influenced by the physician?셲 age, geographic origin, experience or training in male infertility. Conclusions:Conclusions: This study is the largest online survey performed to date on this topic and demonstrates 1) a worldwide under-standing of the importance of this therapeutic option, and 2) a widely prevalent use of antioxidants to treat male infertility. Finally, the necessity of evidence-based clinical practice guidelines from professional societies is highlighted.
    Schlagwörter antioxidants ; male infertility ; oxidative stress ; reproduction ; physicians ; survey ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 310
    Sprache Englisch
    Erscheinungsdatum 2021-07-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data

    Rossella Cannarella / Rupin Shah / Taha Abo-Almagd Abdel-Meguid Hamoda / Florence Boitrelle / Ramadan Saleh / Murat Gul / Amarnath Rambhatla / Parviz Kavoussi / Tuncay Toprak / Ahmed M. Harraz / Edmund Ko / Gökhan Çeker / Damayanthi Durairajanayagam / Noora Alkahidi / Shinnosuke Kuroda / Andrea Crafa / Ralf Henkel / Gianmaria Salvio / Berk Hazir /
    Mahsa Darbandi / Marion Bendayan / Sara Darbandi / Marco Falcone / Raghavender Kosgi / Raneen Sawaid Kaiyal / Keshab Karna / Nguyen Ho Vinh Phuoc / Ponco Birowo / Giovanni M. Colpi / Jean de la Rosette / Germar-Michael Pinggera / Quang Nguyen / Armand Zini / Wael Zohdy / Rajender Singh / Pallavi Saini / Sidney Glina / Haocheng Lin / Taymour Mostafa / Cesar Rojas-Cruz / Mohamed Arafa / Aldo E. Calogero / Fotios Dimitriadis / Priyank Kothari / Vilvapathy Senguttuvan Karthikeyan / Keisuke Okada / Koji Chiba / Ates Kadıoglu / Baris Altay / Tahsin Turunc / Birute Zilaitiene / Fatih Gokalp / Aram Adamyan / Darren Katz / Eric Chung / Tiago Cesar Mierzwa / Daniel Suslik Zylbersztejn / Gustavo Marquesine Paul / Nikolaos Sofikitis / Ioannis Sokolakis / Vineet Malhotra / Sakti Ronggowardhana Brodjonegoro / Ricky Adriansjah / Akira Tsujimura / Toshiyasu Amano / Giancarlo Balercia / Imad Ziouziou / Isaac Ardianson Deswanto / Marlon Martinez / Hyun Jun Park / Mustafa Emre Bakırcıoglu / Erman Ceyhan / Kaan Aydos / Jonathan Ramsay / Suks Minhas / Manaf Al Hashimi / Ramy Abou Ghayda / Nicholas Tadros / Puneet Sindhwani / Christopher C.K. Ho / Rinaldo Indra Rachman / Marcelo Rodriguez Pena / Ahmad Motawi / Arun Karthik Ponnusamy / Satish Dipankar / Azwar Amir / Saleh Binsaleh / Ege Can Serefoglu / Ravi Banthia / Kareim Khalafalla / Ari Basukarno / Nguyen Hoai Bac / Karun Singla / Rafael F. Ambar / Konstantinos Makarounis / Shivam Priyadarshi / Gede Wirya Kusuma Duarsa / Widi Atmoko / Sunil Jindal / Eko Arianto / Hamed Akhavizadegan / Haitham El Bardisi / Ohad Shoshany / Gian Maria Busetto / Mohamad Moussa / Mounir Jamali / Mohamed S. Al-Marhoon / Mikhail Ruzaev / Hasan M. A. Farsi / Shingai Mutambirwa / Dong Sup Lee / Deniz Kulaksiz / Yu-Sheng Cheng / Abderrazak Bouzouita / Selcuk Sarikaya / Hussein Kandil / Georgios Tsampoukas / Ala’a Farkouh / Kasonde Bowa / Missy Savira / Nasser Mogharabian / Tan V. Le / Maruto Harjanggi / Dang Tuan Anh / Tran Quang Tien Long / Mohammad Ayodhia Soebadi / Lukman Hakim / Marko Tanic / Umut Cagin Ari / Firuza R. Parikh / Gokhan Calik / Vinod KV / Gyem Dorji / Andri Rezano / Osvaldo Rajmil / Dung Mai Ba Tien / Yiming Yuan / Juan Francisco Lizarraga-Salas / Balantine Eze / Kay Seong Ngoo / Joe Lee / Umut Arslan / Ashok Agarwal

    The World Journal of Men's Health, Vol 42, Iss 1, Pp 92-

    2024  Band 132

    Abstract: Purpose: The purpose of this meta-analysis is to study the impact of varicocele repair in the largest cohort of infertile males with clinical varicocele by including all available studies, with no language restrictions, comparing intra-person ... ...

    Abstract Purpose: The purpose of this meta-analysis is to study the impact of varicocele repair in the largest cohort of infertile males with clinical varicocele by including all available studies, with no language restrictions, comparing intra-person conventional semen parameters before and after the repair of varicoceles. Materials and Methods: The meta-analysis was performed according to PRISMA-P and MOOSE guidelines. A systematic search was performed in Scopus, PubMed, Cochrane, and Embase databases. Eligible studies were selected according to the PICOS model (Population: infertile male patients with clinical varicocele; Intervention: varicocele repair; Comparison: intraperson before-after varicocele repair; Outcome: conventional semen parameters; Study type: randomized controlled trials [RCTs], observational and case-control studies). Results: Out of 1,632 screened abstracts, 351 articles (23 RCTs, 292 observational, and 36 case-control studies) were included in the quantitative analysis. The before-and-after analysis showed significant improvements in all semen parameters after varicocele repair (except sperm vitality); semen volume: standardized mean difference (SMD) 0.203, 95% CI: 0.129–0.278; p<0.001; I2=83.62%, Egger’s p=0.3329; sperm concentration: SMD 1.590, 95% CI: 1.474–1.706; p<0.001; I2=97.86%, Egger’s p<0.0001; total sperm count: SMD 1.824, 95% CI: 1.526–2.121; p<0.001; I2=97.88%, Egger’s p=0.0063; total motile sperm count: SMD 1.643, 95% CI: 1.318–1.968; p<0.001; I2=98.65%, Egger’s p=0.0003; progressive sperm motility: SMD 1.845, 95% CI: 1.537%–2.153%; p<0.001; I2=98.97%, Egger’s p<0.0001; total sperm motility: SMD 1.613, 95% CI: 1.467%–1.759%; p<0.001; I2=97.98%, Egger’s p<0.001; sperm morphology: SMD 1.066, 95% CI: 0.992%–1.211%; p<0.001; I2=97.87%, Egger’s p=0.1864. Conclusions: The current meta-analysis is the largest to date using paired analysis on varicocele patients. In the current metaanalysis, almost all conventional semen parameters improved significantly ...
    Schlagwörter controlled before-after studies ; infertility ; male ; meta-analysis ; varicocele ; Medicine ; R ; Diseases of the genitourinary system. Urology ; RC870-923
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2024-01-01T00:00:00Z
    Verlag Korean Society for Sexual Medicine and Andrology
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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