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  1. Article ; Online: Right-sided subcutaneous implantable cardioverter-defibrillator placement in a patient with "acquired mesocardia".

    Prousi, George S / Nichols, Judy / Jacob, Sony

    Heart rhythm O2

    2022  Volume 3, Issue 5, Page(s) 587–588

    Language English
    Publishing date 2022-10-21
    Publishing country United States
    Document type Editorial
    ISSN 2666-5018
    ISSN (online) 2666-5018
    DOI 10.1016/j.hroo.2022.08.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: "Third Time's a Charm": Three Times Per Day Dosing of Dofetilide May Be Beneficial in Refractory Atrial Arrhythmias.

    Jacob, Sony / Nichols, Judy / Tanner, Heather / Prousi, George / Smith, Stuart

    The American journal of cardiology

    2022  Volume 176, Page(s) 143–144

    MeSH term(s) Arrhythmias, Cardiac/drug therapy ; Humans ; Phenethylamines ; Sulfonamides/therapeutic use
    Chemical Substances Phenethylamines ; Sulfonamides ; dofetilide (R4Z9X1N2ND)
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Letter
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2022.04.042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs.73: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Grassroots advocacy network. Growing agents of change.

    Nichols, Judy M

    Michigan health & hospitals

    2002  Volume 38, Issue 6, Page(s) 32–33

    MeSH term(s) Community Participation ; Community-Institutional Relations ; Health Care Coalitions ; Hospitals, Community/organization & administration ; Humans ; Michigan ; Patient Advocacy
    Language English
    Publishing date 2002-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: New districts--old results?

    Nichols, Judy M

    Michigan health & hospitals

    2002  Volume 38, Issue 6, Page(s) 16–18

    Abstract: On Nov. 5, Michigan voters will elect legislators in each of Michigan's 15 new congressional districts to serve in Washington, DC, as well as state senators and representatives from newly drawn districts. But will the new districts change the makeup of ... ...

    Abstract On Nov. 5, Michigan voters will elect legislators in each of Michigan's 15 new congressional districts to serve in Washington, DC, as well as state senators and representatives from newly drawn districts. But will the new districts change the makeup of the congressional delegation and the Republican's decade-long hold on majorities in the state House and Senate?
    MeSH term(s) Censuses ; Michigan ; Politics ; United States
    Language English
    Publishing date 2002-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Investigating Serious Adverse Drug Reactions in Patients Receiving Erythropoiesis-Stimulating Agents: A Root Cause Analysis Using the "ANTICIPATE" Framework.

    Jacob, Sony / Nichols, Judy / Macdougall, Iain C / Qureshi, Zaina / Chen, Brian / Yang, Y Tony / Norris, LeAnn B / Bennett, Charles L

    American journal of therapeutics

    2018  Volume 25, Issue 6, Page(s) e670–e674

    Abstract: Background: Unexpected serious adverse drug reactions (sADRs) affecting patients with chronic kidney disease (CKD) who received erythropoiesis-stimulating agents were identified by study co-authors. These included pure red cell aplasia (PRCA) after ... ...

    Abstract Background: Unexpected serious adverse drug reactions (sADRs) affecting patients with chronic kidney disease (CKD) who received erythropoiesis-stimulating agents were identified by study co-authors. These included pure red cell aplasia (PRCA) after administration of the Eprex formulation of epoetin or the epoetin biosimilar HX575 and fatal anaphylaxis associated with peginesatide, an erythropoietin receptor agonist. We developed and applied a structured framework to describe these sADRs, including root cause analyses and eradication efforts.
    Methods: A 10-step framework termed "ANTICIPATE," focusing on signal identification, incidence, causality, and eradication guided our evaluations.
    Results: Initial cases were identified by a hematologist (Eprex), clinical study monitors (HX575), and 4 nurses (peginesatide). The number of persons with individual ADRs was 13 PRCA cases for epoetin, 2 antibody-mediated PRCA cases for HX575, and 5 fatal anaphylaxis cases for peginesatide. Initial incidence estimates per 1000 treated persons were 0.27 for Eprex-associated PRCA, 11 for HX575-associated PRCA, and 0.38 for peginesatide fatalities. Likely causes were subcutaneous administration of epoetin formulated with polysorbate 80 (Eprex), tungsten leaching from pins included in product syringes (HX575), and inclusion of a phenol stabilizer (peginesatide). Eradication strategies included restricting Eprex administration to the intravenous route, excluding tungsten from HX575 syringes, and for peginesatide, proposed eradication was to return to single-dose vials without preservatives.
    Conclusion: Although the number of cases of each sADR was small, eradication was successful for 2 sADRs, and a proposed eradication was developed for a third sADR. The structured framework used to describe the above 3 sADRs in patients with CKD can also be used in other clinical settings.
    MeSH term(s) Anaphylaxis/chemically induced ; Anaphylaxis/epidemiology ; Drug Hypersensitivity/epidemiology ; Drug Hypersensitivity/etiology ; Epoetin Alfa/adverse effects ; Excipients/adverse effects ; Hematinics/adverse effects ; Humans ; Incidence ; Injections, Intravenous/adverse effects ; Injections, Subcutaneous/adverse effects ; Peptides/adverse effects ; Preservatives, Pharmaceutical/adverse effects ; Red-Cell Aplasia, Pure/chemically induced ; Red-Cell Aplasia, Pure/epidemiology ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/complications ; Root Cause Analysis/statistics & numerical data ; Syringes/adverse effects ; Tungsten/adverse effects
    Chemical Substances Excipients ; Hematinics ; Peptides ; Preservatives, Pharmaceutical ; Epoetin Alfa (64FS3BFH5W) ; peginesatide (JX56W9N61Q) ; Tungsten (V9306CXO6G)
    Language English
    Publishing date 2018-08-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1280786-2
    ISSN 1536-3686 ; 1075-2765
    ISSN (online) 1536-3686
    ISSN 1075-2765
    DOI 10.1097/MJT.0000000000000768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4351: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Hydrophobic treatment enabling analysis of wettable surfaces using a liquid microjunction surface sampling probe/electrospray ionization-mass spectrometry system.

    Walworth, Matthew J / Stankovich, Joseph J / Van Berkel, Gary J / Schulz, Michael / Minarik, Susanne / Nichols, Judy / Reich, Eike

    Analytical chemistry

    2011  Volume 83, Issue 2, Page(s) 591–597

    Abstract: An aerosol application procedure involving one or more commercially available silicone-based products was developed to create hydrophobic surfaces that enable analysis of otherwise wettable, absorbent surfaces using a liquid microjunction surface ... ...

    Abstract An aerosol application procedure involving one or more commercially available silicone-based products was developed to create hydrophobic surfaces that enable analysis of otherwise wettable, absorbent surfaces using a liquid microjunction surface sampling probe/electrospray ionization mass spectrometry system. The treatment process resulted in a hydrophobic surface that enabled formation of the requisite probe-to-surface liquid microjunction for sampling and allowed efficient extraction of the analytes from the surface, but did not contribute significant chemical background in the mass spectra. The utility of this treatment process was demonstrated with the treatment of wettable high-performance thin layer chromatography plates, post-plate development, and their subsequent analysis with the sampling probe. The surface treatment process for different surface types was described and explained and the effectiveness of the treatment and subsequent analysis was illustrated using alkaloids from goldenseal (Hydrastis canadensis) root separated on a normal phase silica gel 60 F(254S) plate and peptides from protein tryptic digests separated on a ProteoChrom HPTLC Silica gel 60 F(254S) plate and a ProteoChrom HPTLC Cellulose sheet. This simple surface treatment process significantly expands the analytical surfaces that can be analyzed with the liquid microjunction surface sampling probe, and therefore, also expands the analytical utility of this liquid extraction based surface sampling approach.
    MeSH term(s) Aerosols/chemistry ; Alkaloids/analysis ; Chromatography, Thin Layer/methods ; Hydrastis/chemistry ; Hydrophobic and Hydrophilic Interactions ; Peptides/analysis ; Peptides/isolation & purification ; Plant Roots/chemistry ; Silica Gel/chemistry ; Spectrometry, Mass, Electrospray Ionization/instrumentation ; Spectrometry, Mass, Electrospray Ionization/methods ; Surface Properties ; Wettability
    Chemical Substances Aerosols ; Alkaloids ; Peptides ; Silica Gel (60650-90-0)
    Language English
    Publishing date 2011-01-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/ac102634e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4033: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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