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  1. Article ; Online: The COVID-19 Pandemic Seen from a Syndemic Perspective

    Nicola Luigi Bragazzi

    Infectious Disease Reports, Vol 13, Iss 78, Pp 865-

    The LGBTQIA2SP+ Community

    2021  Volume 871

    Abstract: An adverse condition or a disease can (either directly or indirectly) interact in a synergistic fashion with other adverse conditions or diseases/maladies, and co-cluster together with them: this fundamental observation is at the basis of the term “ ... ...

    Abstract An adverse condition or a disease can (either directly or indirectly) interact in a synergistic fashion with other adverse conditions or diseases/maladies, and co-cluster together with them: this fundamental observation is at the basis of the term “syndemic” (a portmanteau for “synergistic epidemic”) [.]
    Keywords n/a ; Other systems of medicine ; RZ201-999
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Digital Technologies-Enabled Smart Manufacturing and Industry 4.0 in the Post-COVID-19 Era

    Nicola Luigi Bragazzi

    International Journal of Environmental Research and Public Health, Vol 17, Iss 4785, p

    Lessons Learnt from a Pandemic

    2020  Volume 4785

    Abstract: The “Severe Acute Respiratory Syndrome Coronavirus Type 2” (SARS-CoV-2) has been identified as the infectious agent responsible for the generally mild but sometimes life-threatening communicable disease known as “Coronavirus Disease 2019” (COVID-19) [.] ...

    Abstract The “Severe Acute Respiratory Syndrome Coronavirus Type 2” (SARS-CoV-2) has been identified as the infectious agent responsible for the generally mild but sometimes life-threatening communicable disease known as “Coronavirus Disease 2019” (COVID-19) [.]
    Keywords n/a ; Medicine ; R ; covid19
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Back to the “new normal”

    Nicola Luigi BRAGAZZI

    Journal of Health and Social Sciences, Vol 5, Iss 4, Pp 437-

    Researching and publishing in the time of the COVID-19 pandemic

    2020  Volume 440

    Keywords covid-19 ; pandemic ; scholarly research ; Medicine (General) ; R5-920 ; Social sciences (General) ; H1-99
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher Edizioni FS
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Immunological Response to Exercise in Athletes with Disabilities

    Maha Sellami / Luca Puce / Nicola Luigi Bragazzi

    Healthcare, Vol 11, Iss 1692, p

    A Narrative Review of the Literature

    2023  Volume 1692

    Abstract: For a person with a disability, participating in sports activities and/or competitions can be a challenge for the immune system. The relationship between exercise and immunity response in disabled athletes is, indeed, extremely complex for several ... ...

    Abstract For a person with a disability, participating in sports activities and/or competitions can be a challenge for the immune system. The relationship between exercise and immunity response in disabled athletes is, indeed, extremely complex for several reasons, including (1) the chronic low-grade inflammatory and immunodepression—“secondary immune deficiency”—state imposed by the disability/impairment; (2) the impact of the disability on an array of variables, spanning from physical fitness to well-being, quality of life, sleep, and nutritional aspects, among others, which are known to mediate/modulate the effects of exercise on human health; (3) the variability of the parameters related to the exercise/physical activity (modality, frequency, intensity, duration, training versus competition, etc.); and (4) the intra- and inter-individual variability of the immunological response to exercise. In able-bodied athletes, previously published data described several exercise-induced changes affecting various immunological subsets and subpopulations, ranging from neutrophils to lymphocytes, and monocytes. Broadly, moderate intensity workout is accompanied by optimal immunity and resistance to infections such as upper respiratory tract infections (URTI) in athletes. Periods of intense training with insufficient recovery can cause a temporary state of immunosuppression, which should end with a few days of rest/recovery from exercise. Disabled athletes are relatively overlooked and understudied with respect to their able-bodied counterparts. Findings from the few studies available on paralympic and disabled athletes are here summarized and analyzed utilizing a narrative approach to review and determine the major features of the immunological and inflammatory responses to exercise in this specific population. Moreover, a few studies have reported behavioral, dietary, and training strategies that can be adopted to limit exercise-induced immunosuppression and reduce the risk of infection in people with disabilities. However, given ...
    Keywords immune system ; disabled athletes ; infection ; lymphocytes ; cytokines ; narrative review ; Medicine ; R
    Subject code 796
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Declaration of conflict of interest for reviewers in time of COVID-19 should be mandatory

    Francesco Chirico / Nicola Luigi Bragazzi

    Perspectives in Clinical Research, Vol 12, Iss 1, Pp 60-

    2021  Volume 61

    Keywords Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Effects of the COVID-19 pandemic on sexual functioning and activity

    Mojgan Masoudi / Raziyeh Maasoumi / Nicola Luigi Bragazzi

    BMC Public Health, Vol 22, Iss 1, Pp 1-

    a systematic review and meta-analysis

    2022  Volume 18

    Abstract: Abstract Background Since December 2019, when it was first reported in Wuhan, province of Hubei, China, the new virus SARS-CoV-2 has spread rapidly around the world and has become a global pandemic. During the COVID-19 pandemic, due to the public health ... ...

    Abstract Abstract Background Since December 2019, when it was first reported in Wuhan, province of Hubei, China, the new virus SARS-CoV-2 has spread rapidly around the world and has become a global pandemic. During the COVID-19 pandemic, due to the public health measures implemented, people’s sexual activity has also been affected. Restrictions on people’s activities, reduced sports activities, economic issues, increased psychological stress, and reduced entertainment have, indeed, dramatically impacted sexual activity and functioning. The purpose of this study was tosystematically identify, collect and summarize the existing body of evidence from published studies on the effects of COVID-19 pandemic on sexual activity and functioning. Methods Several scholarly databases, namely MEDLINE (via PubMed interface), Web of Science (WOS), Embase, CINAHL, the Cochrane Library, Scopus, and PsycINFO databases, were mined from December 2019 to the end of January 2021. We utilized a random-effect meta-analytical model to analyze all the data. More in detail, the Standardized Mean Difference (SMD) was used in order to estimate and evaluate the effects of the COVID-19 pandemic on sexual activity and functioning. Results Twenty-one studies were included in the present study. In total, 2454 women and 3765 men were evaluated. In the present meta-analysis, sexual functioning and activity were assessed by means of two standardized and reliable tools, namely the “Female Sexual Function Index” (FSFI) and the “International Index of Erectile Function-5 items” (IIEF-5). A total of 5 studies reported the FSFI score before and after the COVID-19 pandemic in female participants. Based on the random-effect model, the SMD was computed to be − 4.26 [95% confidence interval or CI: − 7.26, − 1.25], being statistically significant. A total of 3 studies reported the IIEF-5 score before and after the COVID-19 pandemic in male participants. Based on the random-effect model, the SMD was computed to be − 0.66 [CI 95%: − 0.99, − 0.33], being statistically ...
    Keywords COVID-19 pandemic ; Viral outbreak ; Sexual functioning and activity ; Systematic review and meta-analysis ; Public aspects of medicine ; RA1-1270
    Subject code 150
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Assessing Inequities in COVID-19 Vaccine Roll-Out Strategy Programs

    Mehrdad Kazemi / Nicola Luigi Bragazzi / Jude Dzevela Kong

    Vaccines, Vol 10, Iss 194, p

    A Cross-Country Study Using a Machine Learning Approach

    2022  Volume 194

    Abstract: After the start of the COVID-19 pandemic and its spread across the world, countries have adopted containment measures to stop its transmission, limit fatalities, and relieve hospitals from straining and overwhelming conditions imposed by the virus. Many ... ...

    Abstract After the start of the COVID-19 pandemic and its spread across the world, countries have adopted containment measures to stop its transmission, limit fatalities, and relieve hospitals from straining and overwhelming conditions imposed by the virus. Many countries implemented social distancing and lockdown strategies that negatively impacted their economies and the psychological wellbeing of their citizens, even though they contributed to saving lives. Recently approved and available, COVID-19 vaccines can provide a really viable and sustainable option for controlling the pandemic. However, their uptake represents a global challenge due to vaccine hesitancy and logistic–organizational hurdles that have made its distribution stagnant in several developed countries despite several appeals by the media, policy- and decision-makers, and community leaders. Vaccine distribution is also a concern in developing countries, where there is a scarcity of doses. The objective of the present study was to set up a metric to assess vaccination uptake and identify national socio-economic factors influencing this indicator. We conducted a cross-country study. We first estimated the vaccination uptake rate across countries by fitting a logistic model to reported daily case numbers. Using the uptake rate, we estimated the vaccine roll-out index. Next, we used Random Forest, an “off-the-shelf” machine learning algorithm, to study the association between vaccination uptake rate and socio-economic factors. We found that the mean vaccine roll-out index is 0.016 (standard deviation 0.016), with a range between 0.0001 (Haiti) and 0.0829 (Mongolia). The top four factors associated with the vaccine roll-out index are the median per capita income, human development index, percentage of individuals who have used the internet in the last three months, and health expenditure per capita. The still-ongoing COVID-19 pandemic has shed light on the disparity in vaccine adoption across low- and high-income countries, which represents a global public ...
    Keywords COVID-19 ; pandemic ; vaccine roll-out ; cross-country analysis ; machine learning ; Random forest ; Medicine ; R
    Subject code 300
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: How to Integrate Sex and Gender Medicine into Medical and Allied Health Profession Undergraduate, Graduate, and Post-Graduate Education

    Rola Khamisy-Farah / Nicola Luigi Bragazzi

    Journal of Personalized Medicine, Vol 12, Iss 4, p

    Insights from a Rapid Systematic Literature Review and a Thematic Meta-Synthesis

    2022  Volume 612

    Abstract: Sex and gender are concepts that are often misunderstood and misused, being utilized in a biased, preconceived, interchangeable way. Sex and gender medicine is generally overlooked, despite the profound impact of sex and gender on health outcomes. The ... ...

    Abstract Sex and gender are concepts that are often misunderstood and misused, being utilized in a biased, preconceived, interchangeable way. Sex and gender medicine is generally overlooked, despite the profound impact of sex and gender on health outcomes. The aims of the present rapid systematic literature review were (i) to assess the extent to which sex- and gender-sensitive topics are covered in medical courses; (ii) to assess the need for and willingness toward integrating/incorporating sex and gender medicine into health-related education; (iii) to identify barriers and facilitators of the process of implementation of sex and gender medicine in medical teaching, mentoring, and training; and (iv) to evaluate the effectiveness of interventional projects targeting curriculum building and improvement for future gender-sensitive physicians. Seven themes were identified by means of a thematic analysis, namely, (i) how much sex- and gender-based medicine is covered by medical courses and integrated into current medical curricula, (ii) the knowledge of sex and gender medicine among medical and allied health profession students, (iii) the need for and willingness toward acquiring sex- and gender-sensitive skills, (iv) how to integrate sex- and gender-based medicine into medical curricula in terms of barriers and facilitators, (v) existing platforms and tools to share knowledge related to sex and gender medicine, (vi) sex- and gender-based medicine aspects in the post-medical education, and (vii) the impact of sex- and gender-sensitive topics integrated into medical curricula. Based on the identified gaps in knowledge, further high-quality, randomized trials with larger samples are urgently warranted to fill these gaps in the field of implementation of gender medicine in educating and training future gender-sensitive physicians.
    Keywords sex- and gender-based medicine ; medical education ; medical training ; curriculum building and improvement ; Medicine ; R
    Subject code 390
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Nutrigenomics and Breast Cancer

    Maha Sellami / Nicola Luigi Bragazzi

    Nutrients, Vol 12, Iss 2, p

    State-of-Art, Future Perspectives and Insights for Prevention

    2020  Volume 512

    Abstract: Proper nutrition plays a major role in preventing diseases and, therefore, nutritional interventions constitute crucial strategies in the field of Public Health. Nutrigenomics and nutriproteomics are arising from the integration of nutritional, genomics ... ...

    Abstract Proper nutrition plays a major role in preventing diseases and, therefore, nutritional interventions constitute crucial strategies in the field of Public Health. Nutrigenomics and nutriproteomics are arising from the integration of nutritional, genomics and proteomics specialties in the era of postgenomics medicine. In particular, nutrigenomics and nutriproteomics focus on the interaction between nutrients and the human genome and proteome, respectively, providing insights into the role of diet in carcinogenesis. Further omics disciplines, like metabonomics, interactomics and microbiomics, are expected to provide a better understanding of nutrition and its underlying factors. These fields represent an unprecedented opportunity for the development of personalized diets in women at risk of developing breast cancer.
    Keywords breast cancer ; preventive medicine ; nutrigenomics ; nutriproteomics ; Nutrition. Foods and food supply ; TX341-641
    Subject code 610
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Dataset of non-pharmaceutical interventions and community support measures across Canadian universities and colleges during COVID-19 in 2020

    Haleema Ahmed / Taylor Cargill / Nicola Luigi Bragazzi / Jude Dzevela Kong

    Frontiers in Public Health, Vol

    2022  Volume 10

    Keywords COVID-19 ; pandemic ; policy ; post-secondary ; university ; dataset ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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