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  1. Book ; Thesis: Exzitatorische und inhibitorische Reizeffekte der transkraniellen magnetischen Kortexstimulation bei zerebraler Ischämie

    Niehaus, Ludwig Bernhard

    2003  

    Author's details von Ludwig Bernhard Niehaus
    Language German
    Size 111 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Humboldt-Univ., Habil.-Schr., 2003
    HBZ-ID HT013909809
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Thesis: Thema: Der Einfluß intrakranieller Läsionen auf visuell evozierte Perfusionsänderungen

    Niehaus, Ludwig Bernhard

    eine funktionelle transkranielle dopplersonographische Untersuchung der Arteria cerebri posterior

    1994  

    Author's details von Ludwig Niehaus
    Language German
    Size 105 Bl. : Ill., graph. Darsat.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Humboldt-Univ., Diss., 1994
    Note 2 Mikrofiches
    HBZ-ID HT006587433
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Online ; Thesis: Eine strukturelle Quantifizierung des Locus coeruleus und der Substantia nigra pars compacta im idiopathischen Parkinsonsyndrom mittels neuromelaninsensitiver Magnetresonanztomographie

    Pape, Johanna [Verfasser] / Niehaus, Ludwig Bernhard [Gutachter] / Onur, Özgür Abdullah [Gutachter]

    2022  

    Author's details Johanna Pape ; Gutachter: Ludwig Bernhard Niehaus, Özgür Abdullah Onur
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Otto-von-Guericke-Universität
    Publishing place Magdeburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  4. Book ; Online ; Thesis: Strukturelle und funktionelle Gehirnveränderungen bei Myasthenia gravis

    Klaus, Benita Hildegard Brigitte Verfasser] / [Niehaus, Ludwig Bernhard [Gutachter] / Ziemann, Ulf [Gutachter]

    2022  

    Author's details Benita Hildegard Brigitte Klaus ; Gutachter: Ludwig Bernhard Niehaus, Ulf Ziemann
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Otto-von-Guericke-Universität
    Publishing place Magdeburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  5. Book ; Online ; Thesis: Evaluation des Rupturrisikos von multiplen intrakraniellen Aneurysmen

    Swiatek, Vanessa [Verfasser] / Niehaus, Ludwig Bernhard [Gutachter] / Wrede, Karsten Henning [Gutachter]

    Erarbeitung eines praktikablen Regressionsmodells anhand semiautomatischer, morphologischer Analysen und Blutflusssimulationen individueller 3D-Gefäßrekonstruktionen

    2022  

    Author's details Vanessa Swiatek ; Gutachter: Ludwig Bernhard Niehaus, Karsten Henning Wrede
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek Otto-von-Guericke-Universität
    Publishing place Magdeburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  6. Article: Thrombocytopenia and Intracranial Venous Sinus Thrombosis after "COVID-19 Vaccine AstraZeneca" Exposure.

    Wolf, Marc E / Luz, Beate / Niehaus, Ludwig / Bhogal, Pervinder / Bäzner, Hansjörg / Henkes, Hans

    Journal of clinical medicine

    2021  Volume 10, Issue 8

    Abstract: Background: As of 8 April 2021, a total of 2.9 million people have died with or from the coronavirus infection causing COVID-19 (Corona Virus Disease 2019). On 29 January 2021, the European Medicines Agency (EMA) approved a COVID-19 vaccine developed by ...

    Abstract Background: As of 8 April 2021, a total of 2.9 million people have died with or from the coronavirus infection causing COVID-19 (Corona Virus Disease 2019). On 29 January 2021, the European Medicines Agency (EMA) approved a COVID-19 vaccine developed by Oxford University and AstraZeneca (AZD1222, ChAdOx1 nCoV-19, COVID-19 vaccine AstraZeneca, Vaxzevria, Covishield). While the vaccine prevents severe course of and death from COVID-19, the observation of pulmonary, abdominal, and intracranial venous thromboembolic events has raised concerns.
    Objective: To describe the clinical manifestations and the concerning management of patients with cranial venous sinus thrombosis following first exposure to the "COVID-19 vaccine AstraZeneca".
    Methods: Patient files, laboratory findings, and diagnostic imaging results, and endovascular interventions of three concerning patients were evaluated in retrospect.
    Results: Three women with intracranial venous sinus thrombosis after their first vaccination with "COVID-19 vaccine AstraZeneca" were encountered. Patient #1 was 22 years old and developed headaches four days after the vaccination. On day 7, she experienced a generalized epileptic seizure. Patient #2 was 46 years old. She presented with severe headaches, hemianopia to the right, and mild aphasia 13 days after the vaccination. MRI showed a left occipital intracerebral hemorrhage. Patient #3 was 36 years old and presented 17 days after the vaccination with acute somnolence and right-hand hemiparesis. The three patients were diagnosed with extensive venous sinus thrombosis. They were managed by heparinization and endovascular recanalization of their venous sinuses. They shared similar findings: elevated levels of D-dimers, platelet factor 4 antiplatelet antibodies, corona spike protein antibodies, combined with thrombocytopenia. Under treatment with low-molecular-weight heparin, platelet counts normalized within several days.
    Conclusion: Early observations insinuate that the exposure to the "COVID-19 vaccine AstraZeneca" might trigger the expression of antiplatelet antibodies, resulting in a condition with thrombocytopenia and venous thrombotic events (e.g., intracranial venous sinus thrombosis). These patients' treatment should address the thrombo-embolic manifestations, the coagulation disorder, and the underlying immunological phenomena.
    Language English
    Publishing date 2021-04-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10081599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online ; Thesis: Exzitatorische und inhibitorische Reizeffekte der transkraniellen magnetischen Kortexstimulation bei zerebraler Ischämie

    Niehaus, Ludwig

    2003  

    Author's details von Ludwig Bernhard Niehaus
    Language German
    Size Online-Ressource
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Humboldt-Univ., Habil--Berlin, 2003
    Database Former special subject collection: coastal and deep sea fishing

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  8. Article: Combined Anticoagulation and Antiaggregation in Acute Cervical Artery Dissection.

    von Gottberg, Philipp / Hellstern, Victoria / Wendl, Christina / Wolf, Marc E / Niehaus, Ludwig / Bäzner, Hansjörg / Henkes, Hans

    Journal of clinical medicine

    2021  Volume 10, Issue 19

    Abstract: Cervical artery dissection (CAD) is a frequent cause of stroke in young adults. Previous studies investigating the efficiency of anticoagulation (AC) versus antiplatelet therapy (AT) found an insignificant difference. We therefore retrospectively ... ...

    Abstract Cervical artery dissection (CAD) is a frequent cause of stroke in young adults. Previous studies investigating the efficiency of anticoagulation (AC) versus antiplatelet therapy (AT) found an insignificant difference. We therefore retrospectively evaluated a combination of AC plus AT in patients with acute CAD regarding safety and efficacy. Twenty-eight patients with CAD and minor neurological symptoms/no major infarction received either single (
    Language English
    Publishing date 2021-10-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10194580
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Diagnosis of Parkinson's disease--transcranial sonography in relation to MRI.

    Niehaus, Ludwig / Boelmans, Kai

    International review of neurobiology

    2010  Volume 90, Page(s) 63–79

    Abstract: Displaying the echo pattern (echogenicity) of brain tissue transcranial sonography (TCS) may provide new and complementary information to other neuroimaging methods. In contrast to conventional magnetic resonance imaging (MRI), TCS is able to detect ... ...

    Abstract Displaying the echo pattern (echogenicity) of brain tissue transcranial sonography (TCS) may provide new and complementary information to other neuroimaging methods. In contrast to conventional magnetic resonance imaging (MRI), TCS is able to detect highly characteristic changes in signal brightness of the substantia nigra (SN) in patients with idiopathic Parkinson's disease. In this review, TCS findings are related to conventional and advanced high-field brain MRI findings. On the basis of the MRI findings, especially with T2-relaxometry, the possible role of trace metals in the genesis of altered echogenicity on TCS of brain parenchyma, especially of the SN, are discussed.
    MeSH term(s) Brain Mapping/methods ; Brain Mapping/standards ; Diffusion Magnetic Resonance Imaging/methods ; Diffusion Magnetic Resonance Imaging/standards ; Humans ; Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging/standards ; Parkinson Disease/diagnosis ; Parkinson Disease/diagnostic imaging ; Parkinson Disease/pathology ; Predictive Value of Tests ; Ultrasonography, Doppler, Transcranial/methods ; Ultrasonography, Doppler, Transcranial/standards
    Language English
    Publishing date 2010
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Review
    ZDB-ID 209876-3
    ISSN 2162-5514 ; 0074-7742
    ISSN (online) 2162-5514
    ISSN 0074-7742
    DOI 10.1016/S0074-7742(10)90005-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Seasonal patterns and associations in the incidence of acute ischemic stroke requiring mechanical thrombectomy.

    Bücke, Philipp / Henkes, Hans / Arnold, Guy / Herting, Birgit / Jüttler, Eric / Klötzsch, Christof / Lindner, Alfred / Mauz, Uwe / Niehaus, Ludwig / Reinhard, Matthias / Waibel, Stefan / Horvath, Thomas / Bäzner, Hansjörg / Aguilar Pérez, Marta

    European journal of neurology

    2021  Volume 28, Issue 7, Page(s) 2229–2237

    Abstract: Background: In order to identify risk periods with an increased demand in technical and human resources, we tried to determine patterns and associations in the incidence of acute ischemic stroke due to embolic large vessel occlusions (eLVO) requiring ... ...

    Abstract Background: In order to identify risk periods with an increased demand in technical and human resources, we tried to determine patterns and associations in the incidence of acute ischemic stroke due to embolic large vessel occlusions (eLVO) requiring mechanical thrombectomy (MT).
    Methods: We conducted a time series analysis over a 9-year period (2010-2018) based on observational data in order to detect seasonal patterns in the incidence of MT due to eLVO (n = 2628 patients). In a series of sequential negative binominal regression models, we aimed to detect further associations (e.g., temperature, atmospheric pressure, air pollution).
    Results: There was a 6-month seasonal pattern in the incidence of MT due to eLVO (p = 0.024) peaking in March and September. Colder overall temperature was associated with an increase in MT due to eLVO (average marginal effect [AME], [95% CI]: -0.15 [-0.30-0.0001]; p = 0.05; per °C). A current increase in the average monthly temperature was associated with a higher incidence of MT due to eLVO (0.34 [0.11-0.56]; p = 0.003). Atmospheric pressure was positively correlated with MT due to eLVO (0.38 [0.13-0.64]; p = 0.003; per hectopascal [hPa]). We could detect no causal correlation between air pollutants and MT due to eLVO.
    Conclusions: Our data suggest a 6-month seasonal pattern in the incidence of MT due to eLVO peaking in spring and early autumn. This might be attributed to two different factors: (1) a current temperature rise (comparing the average monthly temperature in consecutive months) and (2) colder overall temperature. These results could help to identify risk periods requiring an adaptation in local infrastructure.
    MeSH term(s) Brain Ischemia/epidemiology ; Humans ; Incidence ; Ischemic Stroke ; Mechanical Thrombolysis ; Seasons ; Stroke/epidemiology ; Thrombectomy ; Treatment Outcome
    Language English
    Publishing date 2021-05-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.14832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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