LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 15

Search options

  1. Article ; Online: Development and performance of NLISA for C-reactive protein detection based on Prussian blue nanoparticle conjugates.

    Nikitina, Maria / Khramtsov, Pavel / Bochkova, Maria / Rayev, Mikhail

    Analytical and bioanalytical chemistry

    2024  Volume 416, Issue 13, Page(s) 3097–3106

    Abstract: Prussian blue nanoparticles (PBNPs), also called nanozymes, are very attractive as an alternative to horseradish peroxidase in immunoassay development due to their simple and low-cost synthesis, stability and high catalytic activity. Today, there is a ... ...

    Abstract Prussian blue nanoparticles (PBNPs), also called nanozymes, are very attractive as an alternative to horseradish peroxidase in immunoassay development due to their simple and low-cost synthesis, stability and high catalytic activity. Today, there is a method for highly effective PBNP synthesis based on the reduction of an FeCl
    MeSH term(s) C-Reactive Protein/analysis ; Ferrocyanides/chemistry ; Humans ; Limit of Detection ; Nanoparticles/chemistry ; Immunoassay/methods ; Colorimetry/methods ; Antibodies, Monoclonal/chemistry ; Enzyme-Linked Immunosorbent Assay/methods
    Chemical Substances C-Reactive Protein (9007-41-4) ; Ferrocyanides ; ferric ferrocyanide (TLE294X33A) ; Antibodies, Monoclonal
    Language English
    Publishing date 2024-04-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 201093-8
    ISSN 1618-2650 ; 0016-1152 ; 0372-7920
    ISSN (online) 1618-2650
    ISSN 0016-1152 ; 0372-7920
    DOI 10.1007/s00216-024-05268-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4' 69/97: Show issues
    Archiv 3: Show issues
    Z 9.4: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article: The Lifespan of

    Balakireva, Yevgenia / Nikitina, Maria / Makhnovskii, Pavel / Kukushkina, Inna / Kuzmin, Ilya / Kim, Alexander / Nefedova, Lidia

    Insects

    2024  Volume 15, Issue 1

    Abstract: 1) Background: ... ...

    Abstract (1) Background: The
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects15010068
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: β-Cyclodextrin Modified Hydrogels of Kappa-Carrageenan for Methotrexate Delivery.

    Nikitina, Maria / Kochkina, Nataliya / Arinina, Marianna / Kulichikhin, Valery / Terekhova, Irina

    Pharmaceutics

    2023  Volume 15, Issue 9

    Abstract: This work is aimed at developing a kappa-carrageenan (kCR) gel with increased methotrexate (MTX) content. β-Cyclodextrin (βCD), which is able to inclusion complex formation with MTX, has been used to increase the drug concentration in the hydrogel. The ... ...

    Abstract This work is aimed at developing a kappa-carrageenan (kCR) gel with increased methotrexate (MTX) content. β-Cyclodextrin (βCD), which is able to inclusion complex formation with MTX, has been used to increase the drug concentration in the hydrogel. The rheological behavior of the designed gels was investigated and the influence of MTX and βCD on the viscoelastic properties of kCR gel was studied in detail. The effect of βCD and its concentration on the MTX-releasing rate from the kCR gels was examined. The properties of kappa- and iota-carrageenans loaded with MTX were compared and the differences observed were explained in terms of different binding affinities of MTX to these polymers. The obtained gels provided desirable viscoelastic properties useful for topical application.
    Language English
    Publishing date 2023-08-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics15092244
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Modular greening technologies for buildings

    Korol Elena / Shushunova Natalia / Nikitina Maria / Shushunova Tatiana

    E3S Web of Conferences, Vol 263, p

    2021  Volume 04031

    Abstract: In this research we provide the analysis of the modern green wall technologies. The modular greening technology for the buildings is universal invention with respect to the purpose of the building and it is applicable for greening buildings intended for ... ...

    Abstract In this research we provide the analysis of the modern green wall technologies. The modular greening technology for the buildings is universal invention with respect to the purpose of the building and it is applicable for greening buildings intended for any spheres of «going into nature» aims. The complexity of installation work of this modular constructive greening system is quite low, which is one of the main advantages of the invention. Due to the fact that the system can be installed both vertically and horizontally, a single coating system of modules is formed. These modules can optimally fill the facades of the building due to the fact that their dimensions can vary. The constructive weight of the system is not large; for this, the technological process is optimized. This system is the most environmentally and technically efficient for the green buildings.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Research of noise-proof feature of addressable fire indication system with sequential addressing

    Balabanov Ivan / Shtonda Daria / Nikitina Maria

    E3S Web of Conferences, Vol 140, p

    2019  Volume 08013

    Abstract: Currently, one of the ways to quickly detect fires in buildings is an automatic fire alarm system. The alarm loop is the most “vulnerable” part of the security and fire alarm system. This article is devoted to the study of the stability of the address ... ...

    Abstract Currently, one of the ways to quickly detect fires in buildings is an automatic fire alarm system. The alarm loop is the most “vulnerable” part of the security and fire alarm system. This article is devoted to the study of the stability of the address fire alarm system with serial addressing under the influence of electromagnetic interference and other interfering factors. During the study, the system performance was evaluated when changing the parameters of the communication line and the stability of the transmission of the measured controlled parameter from the multicriteria detector having a heat and smoke sensor to the control panel of the DEMP DT №1. The influence of electrical impulse noise on the stability of the system was evaluated.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Directed cultivation of Chlorella sorokiniana for the increase in carotenoids’ synthesis

    Kuznetsova Tatiana / Ivanchenko Olga / Trukhina Elena / Nikitina Maria / Kiseleva Anastasia

    E3S Web of Conferences, Vol 161, p

    2020  Volume 01051

    Abstract: The metabolism of Chlorella sorokiniana is subjected to changes caused by various cultivation conditions. If dosed ultraviolet radiation is used, there is a possibility of a compensatory increase in the synthesis of carotenoids which prevent oxidative ... ...

    Abstract The metabolism of Chlorella sorokiniana is subjected to changes caused by various cultivation conditions. If dosed ultraviolet radiation is used, there is a possibility of a compensatory increase in the synthesis of carotenoids which prevent oxidative stress. Strain 211-8k was cultured under various lighting conditions: control sample was subjected to fluorescent light; sample 1 was subjected to dosed periodic ultraviolet irradiation for 15 minutes every day and fluorescent lighting; sample 2 was subjected to ultraviolet irradiation for 30 minutes in the stabilization phase. Periodic UV exposure negatively affects the population growth of C. sorokiniana which was possible to detect only on the ninth day and the biomass yield significantly decreased. A single UV exposure for 30 minutes lead to a slight decrease in the yield of air-dry biomass which with a further population growth may be compensated. Periodic exposure to UV radiation stimulates carotenoids synthesis, the yield in terms of dry biomass exceeded the control sample on average by 30%. A single ultraviolet irradiation for 30 minutes in the stabilization phase lead to a decrease in the biomass content of both chlorophyll and carotenoids. Microscopy of microalgae showed that ultraviolet radiation leads to the formation of cells with signs of apoptosis.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Macro- and microtranscriptomic evidence of the monocyte recruitment to regenerating liver after partial hepatectomy in mouse model.

    Elchaninov, Andrey / Nikitina, Maria / Vishnyakova, Polina / Lokhonina, Anastasia / Makarov, Andrey / Sukhikh, Gennady / Fatkhudinov, Timur

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2021  Volume 138, Page(s) 111516

    Abstract: Macrophages are important regulators of liver repair. Participation of migratory monocytes/macrophages in regeneration of hepatic tissues after resection remains disputable. In mouse the resection promotes migration of Ly6C+CD11b+ monocytes/macrophages ... ...

    Abstract Macrophages are important regulators of liver repair. Participation of migratory monocytes/macrophages in regeneration of hepatic tissues after resection remains disputable. In mouse the resection promotes migration of Ly6C+CD11b+ monocytes/macrophages to the remnant liver accompanied by a reduction in its CD206 + macrophage content. Macrophage proliferation within the liver reaches maximum on day 3 after the surgery. Corresponding macro- and microtranscriptomic profiles of macrophages in regeneration liver cannot be unambiguously defined as pro- or anti-inflammatory. Their typical features include elevated expression of leukocyte chemoattractant factors, and many of the differentially expressed sequences are related to the control of cell growth and metabolic processes in the liver. These findings revealed essential roles of immigration of monocytes/macrophages and macrophages proliferation in maintenance of macrophage populations in the mouse liver during its recovery from a massive resection.
    MeSH term(s) Animals ; Cells, Cultured ; Disease Models, Animal ; Hepatectomy/methods ; Ki-67 Antigen/biosynthesis ; Ki-67 Antigen/genetics ; Ki-67 Antigen/immunology ; Liver/immunology ; Liver/metabolism ; Liver/surgery ; Liver Regeneration/physiology ; Macrophages/immunology ; Macrophages/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; Monocytes/immunology ; Monocytes/metabolism ; Transcriptome/physiology
    Chemical Substances Ki-67 Antigen
    Language English
    Publishing date 2021-03-23
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2021.111516
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.198: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Assessment of soil and plant cover contamination by heavy metals of the Bolshoi Solovetsky Island.

    Popova Lyudmila / Andreeva Yulia / Nikitina Maria

    Principy Èkologii , Vol 2016, Iss 2, Pp 62-

    2016  Volume 69

    Abstract: Under the influence of anthropogenic load on the territory of the Solovetsky archipelago the study of the soil and plant cover for the presence of pollutants becomes crucial. As a part of the educational project "Integrated development of the territory ... ...

    Abstract Under the influence of anthropogenic load on the territory of the Solovetsky archipelago the study of the soil and plant cover for the presence of pollutants becomes crucial. As a part of the educational project "Integrated development of the territory with unique natural, historic and cultural heritage on the example of the Solovki " the content of heavy metals such as Pb, Zn, Cu, Ni, Co, Fe, Mn, Cr, V, Ti, Sr in the soil and vegetation in the village of Bolshoi Solovetsky was analyzed. In general, in the surface layer of the soil Pb, Zn, Fe and Ti are mainly accumulated, in the soil of some areas there is a high concentration of Mn and V. For the majority of samples the allowable contamination level was marked, but two test areas can be attributed to the extremely dangerous. In the vegetation the content of the majority of the metals in question exceeds significantly the permissible normal value that corresponds to the substantial pollution level
    Keywords тяжелые металлы ; почвенный и растительный покров ; остров Большой Соловецкий ; Ecology ; QH540-549.5
    Subject code 910
    Language Russian
    Publishing date 2016-06-01T00:00:00Z
    Publisher Petrozavodsk State University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Possible cause of lack of positive samples on homologous blood transfusion.

    Krotov, Grigory / Nikitina, Maria / Rodchenkov, Grigory

    Drug testing and analysis

    2014  Volume 6, Issue 11-12, Page(s) 1160–1162

    Abstract: Homologous blood transfusion is a prohibited method of blood manipulation that can be used to increase the number of erythrocytes circulating in the blood stream resulting in an increased oxygen transport capacity. In doping controls, homologous blood ... ...

    Abstract Homologous blood transfusion is a prohibited method of blood manipulation that can be used to increase the number of erythrocytes circulating in the blood stream resulting in an increased oxygen transport capacity. In doping controls, homologous blood transfusions are determined by means of a procedure based on the detection of red blood cell phenotypes by flow cytometry. In the past six years, no adverse analytical findings concerning homologous blood transfusions were reported. One explanation for that phenomenon, assuming that athletes have not completely given up this kind of manipulation, would be a more careful selection of potential donors. If such a donor has the same set of minor erythrocyte antigens as the recipient, the established methodology to detect homologous transfusion would fail. We have hypothesized that any athlete can be a potential donor for teammates with the same RhD factor and AB0 blood group. Having analyzed the phenotype of erythrocytes of 535 Russian athletes in various endurance sports, several pairs of athletes with the same phenotype were observed. Based on the frequency of occurrence of red blood cell antigens, the theoretical probability of finding a donor within a team with exactly the same phenotype was calculated, and the existing number of occurrences where two individuals share the same phenotype in the same sport was in fact five times higher than the theoretical probability.
    MeSH term(s) Athletes ; Blood Transfusion/methods ; Doping in Sports ; Erythrocytes/chemistry ; Flow Cytometry ; Humans ; Phenotype ; Russia
    Language English
    Publishing date 2014-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2462336-2
    ISSN 1942-7611 ; 1942-7603
    ISSN (online) 1942-7611
    ISSN 1942-7603
    DOI 10.1002/dta.1736
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6792: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Expression of Estrogen Receptor α by Decidual Macrophages in Preeclampsia.

    Vishnyakova, Polina / Poltavets, Anastasiya / Nikitina, Maria / Midiber, Konstantin / Mikhaleva, Liudmila / Muminova, Kamilla / Potapova, Alena / Khodzhaeva, Zulfiya / Pyregov, Alexey / Elchaninov, Andrey / Fatkhudinov, Timur / Sukhikh, Gennady

    Biomedicines

    2021  Volume 9, Issue 2

    Abstract: Preeclampsia is a gestation-associated hypertensive syndrome that threatens the life and health of the mother and the child. The condition is presumably caused by systemic failure with a strong involvement of innate immunity. In particular, it has been ... ...

    Abstract Preeclampsia is a gestation-associated hypertensive syndrome that threatens the life and health of the mother and the child. The condition is presumably caused by systemic failure with a strong involvement of innate immunity. In particular, it has been associated with flexible phenotypes of macrophages, which depend on the molecules circulating in the blood and tissue fluid, such as cytokines and hormones. This study aimed at a comparative evaluation of pro-inflammatory (TNFα) and anti-inflammatory (CD206, MMP9, HGF) markers, as well as the levels of estrogen receptor α, expressed by decidual macrophages in normal pregnancy and in patients with early- and late-onset preeclampsia. The tissue samples of decidua basalis were examined by immunohistochemistry and Western blotting. Isolation of decidual macrophages and their characterization were performed using cultural methods, flow cytometry and real-time PCR. Over 50% of the isolated decidual macrophages were positive for the pan-macrophage marker CD68. In the early-onset preeclampsia group, the levels of estrogen receptor α in decidua were significantly decreased. Furthermore, significantly decreased levels of HGF and CD206 were observed in both preeclampsia groups compared with the control group. The observed downregulation of estrogen receptor α, HGF and CD206 may contribute to the balance of pro- and anti-inflammatory macrophages and thereby to pathogenesis of preeclampsia.
    Language English
    Publishing date 2021-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines9020191
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top