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  1. Book: Die Extremitätenischämie

    Nikol, Sigrid

    (UNI-MED science)

    2012  

    Author's details [Sigrid Nikol ...]
    Series title UNI-MED science
    Keywords Periphere arterielle Verschlusskrankheit
    Subject Arterielle Verschlusskrankheit ; Periphere arterielle Durchblutungsstörung ; PAVK
    Language German
    Size 173 S. : zahlr. Ill., graph. Darst.
    Edition 1. Aufl.
    Publisher UNI-MED-Verl
    Publishing place Bremen u.a.
    Publishing country Germany
    Document type Book
    Note Literaturangaben
    HBZ-ID HT017236318
    ISBN 978-3-8374-1164-5 ; 3-8374-1164-8
    Database Catalogue ZB MED Medicine, Health

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    2012 A 2115 order for loan Magazin

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  2. Article: Update Aortenerkrankungen

    Nikol, Sigrid / Nikol, Laetitia

    Aktuelle Kardiologie

    2022  Volume 11, Issue 02, Page(s) 166–176

    Abstract: Die vorliegende Arbeit berichtet über die neuesten wissenschaftlichen Erkenntnisse im Zusammenhang mit Aortenaneurysmen und -dissektionen. Schwerpunkt hierbei sind die Pathophysiologie und Genetik, der Einfluss von Fluorochinolonen auf ... ...

    Abstract Die vorliegende Arbeit berichtet über die neuesten wissenschaftlichen Erkenntnisse im Zusammenhang mit Aortenaneurysmen und -dissektionen. Schwerpunkt hierbei sind die Pathophysiologie und Genetik, der Einfluss von Fluorochinolonen auf Aortenaneurysmen und -dissektionen sowie Marker der Aortitis. Ferner werden die wichtigsten aktuellen Leitlinienempfehlungen aus den Jahren 2017 bis 2020 zusammengefasst – der Fokus liegt hierbei auf dem Screening, der Diagnostik, den Grenzwerten für die Therapieindikationen, der Art und den technischen Details der Behandlung sowie Nachsorge von Aneurysmen der Aorta ascendens, des Aortenbogens, der Aorta descendens und abdominalis, Penetrating aortic Ulcers, bei genetisch bedingten Bindegewebserkrankungen mit Aortenbeteiligungen, Aortitis und mykotischen Aneurysmen.
    Keywords Aneurysma ; Dissektion ; Aortitis ; endovaskuläre Therapie ; rupturiertes Aortenaneurysma ; aneurysm ; dissection ; ruptured aortic aneurysm ; aortitis ; endovascular therapy
    Language German
    Publishing date 2022-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2654127-0
    ISSN 2193-5211 ; 2193-5203
    ISSN (online) 2193-5211
    ISSN 2193-5203
    DOI 10.1055/a-1746-8079
    Database Thieme publisher's database

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  3. Article ; Online: Clinical experience with dual pathway inhibition therapy: case series and mini review.

    Geisler, Tobias / Branch, Kelley / Nikol, Sigrid

    European heart journal. Case reports

    2022  Volume 6, Issue 7, Page(s) ytac201

    Abstract: Background: Dual pathway inhibition (DPI) with rivaroxaban 2.5 mg twice daily plus aspirin has demonstrated reductions in major adverse cardiovascular and limb events in eligible patients with chronic coronary artery disease (CAD), peripheral artery ... ...

    Abstract Background: Dual pathway inhibition (DPI) with rivaroxaban 2.5 mg twice daily plus aspirin has demonstrated reductions in major adverse cardiovascular and limb events in eligible patients with chronic coronary artery disease (CAD), peripheral artery disease, or both. Patients with polyvascular disease, heart failure, renal impairment, or diabetes can benefit particularly from this therapy. We present our clinical experience to elucidate practical issues regarding the selection of patients eligible for DPI and the timing of initiation.
    Case summary: The first patient was at high risk of recurrent cardiovascular events due to his history of multi-vessel CAD, myocardial infarction, heart failure, and diabetes. Following a period of post-myocardial infarction dual antiplatelet therapy, he was transitioned to DPI therapy. The second patient was at high risk of cardiovascular events due to his history of polyvascular disease, diffuse CAD, and diabetes. He was hospitalized for unstable angina, which was medically managed because no target lesion was identified. DPI was initiated a day after admission. The third patient was at high risk of cardiovascular events due to an extensive history of polyvascular disease, revascularization, and renal impairment. Although the patient was asymptomatic at routine follow-up, DPI was initiated to reduce the risk of further cardiovascular events.
    Discussion: In eligible patients who are at high risk of cardiovascular events, DPI therapy with low-dose rivaroxaban should be considered. Treatment can be started at various times, including at the end of dual antiplatelet therapy, at routine follow-up, or after new events or diagnoses.
    Language English
    Publishing date 2022-05-19
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytac201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Thesis: Die Geschichte des Medizinalwesens und die traditionelle Heilkunde der karibischen Insel Dominica

    Nikol, Sigrid

    (Studien zur Geschichte des Krankenhauswesens ; 26)

    1987  

    Series title Studien zur Geschichte des Krankenhauswesens ; 26
    Collection
    Keywords Health Services / history / Netherlands Antilles ; Dominica ; Gesundheitswesen ; Geschichte ; Volksmedizin ; Medizin
    Subject Landesgeschichte ; Regionalgeschichte ; Ortsgeschichte ; Zeitgeschichte ; Humanmedizin ; Heilkunst ; Medicine ; Volksheilkunde ; Volkstümliche Medizin ; Gesundheitsdienst ; Gesundheitssystem ; Gesundheitswirtschaft ; Medizinalwesen ; Medizinalsystem
    Language German
    Size 571 S. : Ill., graph. Darst., Kt.
    Publisher Murken-Altrogge
    Publishing place Herzogenrath
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Aachen, Techn. Hochschule, Diss., 1987
    HBZ-ID HT003515051
    ISBN 3-921801-35-4 ; 978-3-921801-35-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1990 B 922 order for loan Magazin

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  5. Book ; Thesis: Die Geschichte des Medizinalwesens und die traditionelle Heilkunde der karibischen Insel Dominica

    Nikol, Sigrid

    1987  

    Author's details Sigrid Nikol
    Keywords Dominica ; Medizinische Versorgung ; Geschichte 1700-1982 ; Heilpflanzen ; Phytotherapie
    Subject Pflanzenmedizin ; Arzneipflanzen ; Drogenpflanzen ; Heilkräuter ; Kräuter ; Medizinalpflanzen ; Heilpflanze ; Gesundheitsversorgung ; Gesundheitliche Versorgung ; Patientenversorgung
    Language German
    Size 571 S. : Ill.
    Publisher Murken-Altrogge
    Publishing place Herzogenrath
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Aachen, Techn. Hochsch., Diss., 1987
    HBZ-ID HT003223307
    ISBN 3-921801-35-4 ; 978-3-921801-35-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
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  6. Book: Die Extremitätenischämie

    Nikol, Sigrid

    (UNI-MED science)

    2012  

    Author's details [Sigrid Nikol, Herausgeberin]
    Series title UNI-MED science
    MeSH term(s) Peripheral Arterial Disease
    Language German
    Size 173 p. :, ill., ports.
    Publisher UNI-MED
    Publishing place Bremen
    Document type Book
    ISBN 9783837411645 ; 3837411648
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Article ; Online: Stammzelltherapie in der Gefäßmedizin.

    Nikol, Sigrid

    Zentralblatt fur Chirurgie

    2011  Volume 136, Issue 5, Page(s) 399–403

    Title translation Stem cell therapy in vascular medicine.
    MeSH term(s) Adipose Tissue/cytology ; Arterial Occlusive Diseases/physiopathology ; Arterial Occlusive Diseases/therapy ; Bone Marrow Transplantation ; Endothelium, Vascular/physiopathology ; Granulocyte Colony-Stimulating Factor/blood ; Granulocyte-Macrophage Colony-Stimulating Factor/blood ; Hematopoietic Stem Cell Transplantation ; Humans ; Intermittent Claudication/physiopathology ; Intermittent Claudication/therapy ; Ischemia/physiopathology ; Ischemia/therapy ; Leg/blood supply ; Macrophage Colony-Stimulating Factor/blood ; Mesenchymal Stem Cell Transplantation ; Monocytes/transplantation ; Neovascularization, Physiologic/physiology ; Stem Cell Transplantation
    Chemical Substances Granulocyte Colony-Stimulating Factor (143011-72-7) ; Macrophage Colony-Stimulating Factor (81627-83-0) ; Granulocyte-Macrophage Colony-Stimulating Factor (83869-56-1)
    Language German
    Publishing date 2011-04-30
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 200935-3
    ISSN 1438-9592 ; 0044-409X
    ISSN (online) 1438-9592
    ISSN 0044-409X
    DOI 10.1055/s-0031-1293139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Durchblutungsstörungen. Kranke Gefäße - gefährdetes Herz

    Mathias, Klaus / Nikol, Sigrid

    Herz heute

    2019  Volume 39, Issue 2, Page(s) 10

    Language German
    Document type Article
    ZDB-ID 1474834-4
    ISSN 1437-5176
    Database Current Contents Medicine

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    Zs.A 6982: Show issues Location:
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  9. Article: 5 Conservative treatment for PAD - Risk factor management.

    Frank, Ulrich / Nikol, Sigrid / Belch, Jill

    VASA. Zeitschrift fur Gefasskrankheiten

    2019  Volume 48, Issue Suppl 102, Page(s) 1–12

    MeSH term(s) Conservative Treatment ; Humans ; Peripheral Arterial Disease/therapy ; Risk Factors
    Language English
    Publishing date 2019-10-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 120977-2
    ISSN 1664-2872 ; 0301-1526
    ISSN (online) 1664-2872
    ISSN 0301-1526
    DOI 10.1024/0301-1526/a000835
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Gene therapy of cardiovascular disease.

    Nikol, Sigrid

    Current opinion in molecular therapeutics

    2008  Volume 10, Issue 5, Page(s) 479–492

    Abstract: Coronary and peripheral artery diseases are highly prevalent and characterized by an unmet requirement for medical treatment in the more advanced stages. These shortcomings comprise the requirement for vessel regeneration using therapeutic angiogenesis ... ...

    Abstract Coronary and peripheral artery diseases are highly prevalent and characterized by an unmet requirement for medical treatment in the more advanced stages. These shortcomings comprise the requirement for vessel regeneration using therapeutic angiogenesis as well as the prevention of post-angioplasty restenosis using local gene therapy. Both therapeutic angiogenesis and gene therapy to prevent post-angioplasty restenosis have undergone extensive research in the past 17 years and have led to a number of phase II clinical trials and a phase III approval trial. The development of therapeutic strategies based on gene therapy over the last 7 years is reviewed, including data from animal studies as well as phase II clinical trials.
    MeSH term(s) Cardiovascular Diseases/genetics ; Cardiovascular Diseases/therapy ; Clinical Trials, Phase II as Topic ; Clinical Trials, Phase III as Topic ; Genetic Therapy/methods ; Graft Occlusion, Vascular/genetics ; Graft Occlusion, Vascular/prevention & control ; Humans ; Neovascularization, Physiologic/genetics
    Language English
    Publishing date 2008-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2022273-7
    ISSN 1464-8431
    ISSN 1464-8431
    Database MEDical Literature Analysis and Retrieval System OnLINE

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