LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 50

Search options

  1. Article: Deep-Learning-Guided Student Intelligent Classroom Management System.

    Niu, Xiaobing

    publication RETRACTED

    Applied bionics and biomechanics

    2022  Volume 2022, Page(s) 1961631

    Abstract: Aiming at the limitations of old-fashioned instructing knowledge and the insufficiency of existing dynamically managed classrooms, a deep-learning-guided Unity3D-based intelligent classroom management system and the corresponding instrument support were ... ...

    Abstract Aiming at the limitations of old-fashioned instructing knowledge and the insufficiency of existing dynamically managed classrooms, a deep-learning-guided Unity3D-based intelligent classroom management system and the corresponding instrument support were proposed. We first build a virtual scene and import Unity3D motors, in order to improve practical fake action proofs through C# script and prefix system. Subsequently, we attempt to solve the permission arrangement proposition in multiperson entity scenes, and accordingly, we complete the cognitive assistance module using authorization strategy. Our system can provide different students with tailored permissions, foresee text, video, and some flexible functions. Our system can be divided into multiple Spring Cloud frameworks. We further leverage the Redis to optimize the system architecture. The system can be conveniently applied in chemistry instructing with clear virtual auditions under the government direct supervision. It can effectively address authority issues in real scenarios while enhancing the learning efficiency and increasing accessibility. A set of intelligent classroom behavior system based on deep learning that supported by cunning learning methods are proposed accordingly. It can complete the classroom perception ministry. It can optimally conduct status monitoring as well as classroom assignment and discussion services through deep learning vision techniques such as face perception and facial expression analysis. Extensive experimental results have shown the competitive performance of our method.
    Language English
    Publishing date 2022-08-26
    Publishing country Egypt
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2179924-6
    ISSN 1754-2103 ; 1176-2322
    ISSN (online) 1754-2103
    ISSN 1176-2322
    DOI 10.1155/2022/1961631
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Solitary Fibrous Tumor of the Prostate Shown on FAPI PET/CT.

    Yang, Tianshuo / Zhu, Ronghua / Guo, Zhongying / Niu, Xiaobing / Tao, Weijing

    Clinical nuclear medicine

    2023  Volume 48, Issue 6, Page(s) 530–531

    Abstract: Abstract: Solitary fibrous tumors are fibroblast tumors that occur mainly in the peritoneum, extremities, and pleura. Here, we report the MRI, FDG PET/CT, and FAPI PET/CT findings of a rare prostate solitary fibrous tumor. A 57-year-old man was ... ...

    Abstract Abstract: Solitary fibrous tumors are fibroblast tumors that occur mainly in the peritoneum, extremities, and pleura. Here, we report the MRI, FDG PET/CT, and FAPI PET/CT findings of a rare prostate solitary fibrous tumor. A 57-year-old man was pathologically diagnosed with a solitary fibrous tumor. To detect any systemic metastases or other primary lesions, the patient underwent FDG PET/CT and FAPI PET/CT examination sequentially. Mild FDG uptake was observed in the primary prostatic lesion, but there was a significant uptake of FAPI in the prostate. This case highlighted that FAPI PET/CT may outperform FDG PET/CT in identifying solitary fibrous tumors.
    MeSH term(s) Male ; Humans ; Middle Aged ; Positron Emission Tomography Computed Tomography ; Prostate ; Fluorodeoxyglucose F18 ; Solitary Fibrous Tumors/diagnostic imaging ; Hemangiopericytoma ; Gallium Radioisotopes
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Gallium Radioisotopes
    Language English
    Publishing date 2023-03-26
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000004635
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Distributed model-free formation control of networked fully-actuated autonomous surface vehicles.

    Niu, Xiaobing / Gao, Shengnan / Xu, Zhibin / Feng, Shiliang

    Frontiers in neurorobotics

    2022  Volume 16, Page(s) 1028656

    Abstract: This paper presents a distributed constant bearing guidance and model-free disturbance rejection control method for formation tracking of autonomous surface vehicles subject to fully unknown kinetic model. First, a distributed constant bearing guidance ... ...

    Abstract This paper presents a distributed constant bearing guidance and model-free disturbance rejection control method for formation tracking of autonomous surface vehicles subject to fully unknown kinetic model. First, a distributed constant bearing guidance law is designed at the kinematic level to achieve a consensus task. Then, by using an adaptive extended state observer (AESO) to estimate the total uncertainties and unknown input coefficients, a simplified model-free kinetic controller is designed based on a dynamic surface control (DSC) design. It is proven that the closed-loop system is input-to-state stable The stability of the closed-loop system is established. A salient feature of the proposed method is that a cooperative behavior can be achieved without knowing any priori information. An application to formation control of autonomous surface vehicles is given to show the efficacy of the proposed integrated distributed constant bearing guidance and model-free disturbance rejection control.
    Language English
    Publishing date 2022-09-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2453002-5
    ISSN 1662-5218
    ISSN 1662-5218
    DOI 10.3389/fnbot.2022.1028656
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Molecular classification of patients with NMIBC predicts the efficacy of intravesical chemotherapy with pirarubicin, pharmorubicin and gemcitabine-immunohistochemistry-based classification.

    Wang, Tianwei / Niu, Xiaobing / Zhong, Bing

    Japanese journal of clinical oncology

    2022  Volume 52, Issue 6, Page(s) 642–649

    Abstract: Objective: To investigate the relationships between non-muscle invasive bladder cancer molecular subtypes and predict the efficacy of intravesical chemotherapy with pirarubicin, pharmorubicin and gemcitabine.: Methods: A total of 160 patients with T1 ...

    Abstract Objective: To investigate the relationships between non-muscle invasive bladder cancer molecular subtypes and predict the efficacy of intravesical chemotherapy with pirarubicin, pharmorubicin and gemcitabine.
    Methods: A total of 160 patients with T1 stage non-muscle invasive bladder cancer were enrolled in this study. Fifty-three patients underwent anthracycline (Pirarubicin and Pharmorubicin) therapy and 107 patients accepted gemcitabine therapy. Uroplakin II and CK20 were categorized as immunohistochemistry (IHC) markers for luminal subtype, whereas CK5/6 and CD44 were categorized as immunohistochemistry markers for basal subtype. The cluster results with immunohistochemical score indicated that non-muscle invasive bladder cancer can be subgrouped into three major classes.
    Results: Class 2 showed the luminal-like characteristics, whereas class 3 showed the basal-like characteristics. Class 1 showed no high expression of luminal or basal-associated immunohistochemistry markers. The molecular subtype is an independent risk factor for recurrence-free survival (P = 0.030) and progression-free survival (P = 0.006) in patients with T1 stage non-muscle invasive bladder cancer. In class 1 and class 2 (luminal-like) subtypes, gemcitabine and anthracycline show no difference in recurrence-free survival and progression-free survival. Gemcitabine was associated with reduced recurrence compared with anthracycline (P = 0.039) in class 3 (basal-like) subtypes and show no difference in decreasing progression.
    Conclusions: The molecular classification based on immunohistochemical results is an independent risk factor for the prognosis of non-muscle invasive bladder cancer with T1 stage. Different therapeutic methods should be selected according to different molecular subtypes.
    MeSH term(s) Administration, Intravesical ; Anthracyclines/therapeutic use ; Antibiotics, Antineoplastic/therapeutic use ; Deoxycytidine/analogs & derivatives ; Doxorubicin/analogs & derivatives ; Epirubicin/therapeutic use ; Humans ; Immunohistochemistry ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local/drug therapy ; Urinary Bladder Neoplasms/drug therapy
    Chemical Substances Anthracyclines ; Antibiotics, Antineoplastic ; Deoxycytidine (0W860991D6) ; Epirubicin (3Z8479ZZ5X) ; Doxorubicin (80168379AG) ; gemcitabine (B76N6SBZ8R) ; pirarubicin (D58G680W0G)
    Language English
    Publishing date 2022-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 190978-2
    ISSN 1465-3621 ; 0368-2811
    ISSN (online) 1465-3621
    ISSN 0368-2811
    DOI 10.1093/jjco/hyac042
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Development and first-in-human study of PSMA-targeted PET tracers with improved pharmacokinetic properties.

    Hou, Haodong / Pan, Yuan / Wang, Yanzhi / Ma, Yuze / Niu, Xiaobing / Sun, Suan / Hou, Guihua / Tao, Weijing / Gao, Feng

    European journal of nuclear medicine and molecular imaging

    2024  

    Abstract: Purpose: A series of new : Methods: We introduced quinoline group, phenylalanine and decanoic acid into different tracers to enhance their lipophilicity, strategically limiting their metabolic pathway through the urinary system. Their binding ... ...

    Abstract Purpose: A series of new
    Methods: We introduced quinoline group, phenylalanine and decanoic acid into different tracers to enhance their lipophilicity, strategically limiting their metabolic pathway through the urinary system. Their binding affinity onto LNCaP cells was determined through in vitro saturation assays and competition binding assays. In vivo metabolic study, PET imaging and biodistribution experiment were performed in LNCaP tumor-bearing B-NSG male mice. The most promising tracer was selected for first-in-human study.
    Results: Four radiotracers were synthesized with radiochemical purity (RCP) > 95% and molar activity in a range of 20.0-25.5 GBq/μmol. The binding affinities (K
    Conclusion: Introduction of quinoline group, phenylalanine and decanoic acid into different tracers can modulate the binding affinity and pharmacokinetics of PSMA in vivo. [
    Trial registration: The clinical evaluation of this study was registered On October 30, 2021 at https://www.chictr.org.cn/ (No: ChiCTR2100052545).
    Language English
    Publishing date 2024-04-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 8236-3
    ISSN 1619-7089 ; 0340-6997 ; 1619-7070
    ISSN (online) 1619-7089
    ISSN 0340-6997 ; 1619-7070
    DOI 10.1007/s00259-024-06726-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: [Corrigendum] MicroRNA‑335 is downregulated in bladder cancer and inhibits cell growth, migration and invasion via targeting ROCK1.

    Wu, Deyao / Niu, Xiaobing / Pan, Huixing / Zhou, Yunfeng / Qu, Ping / Zhou, Jian

    Molecular medicine reports

    2022  Volume 26, Issue 3

    Abstract: Subsequently to the publication of this paper, an interested reader drew to the authors' attention that, in Fig. 3 on p. 4382, the 'Invasion' assay data for the negative control (NC) experiments for the T24 and EJ cell lines appeared to contain an ... ...

    Abstract Subsequently to the publication of this paper, an interested reader drew to the authors' attention that, in Fig. 3 on p. 4382, the 'Invasion' assay data for the negative control (NC) experiments for the T24 and EJ cell lines appeared to contain an overlap of data, such that they may have been derived from the same original source even though the data were purportedly intended to show the results from differently peformed experiments. The authors have re‑examined their original data, and realize that this figure was inadvertently assembled incorrectly. The revised version of Fig. 3, showing alternative data from one of the repeated experiments, is shown below. Note that this error did not significantly affect either the results or the conclusions reported in this paper, and all the authors agree to this corrigendum. Furthermore, the authors thank the Editor of
    Language English
    Publishing date 2022-07-27
    Publishing country Greece
    Document type Published Erratum
    ZDB-ID 2469505-1
    ISSN 1791-3004 ; 1791-2997
    ISSN (online) 1791-3004
    ISSN 1791-2997
    DOI 10.3892/mmr.2022.12799
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Retracted Article: Long noncoding RNA PCA3 regulates glycolysis, viability and apoptosis by mediating the miR-1/CDK4 axis in prostate cancer.

    Gu, Shuo / Niu, Xiaobing / Mao, Fei / Xu, Zongyuan

    publication RETRACTED

    RSC advances

    2018  Volume 8, Issue 66, Page(s) 37564–37572

    Abstract: Prostate cancer is one of the common tumor malignancies in men worldwide. Although long noncoding RNAs (lncRNAs) have been demonstrated to play essential roles in the progression of prostate cancer, the roles and potential mechanism of lncRNA prostate ... ...

    Abstract Prostate cancer is one of the common tumor malignancies in men worldwide. Although long noncoding RNAs (lncRNAs) have been demonstrated to play essential roles in the progression of prostate cancer, the roles and potential mechanism of lncRNA prostate cancer antigen 3 (PCA3) remain poorly understood. In the present study, we investigated the role of PCA3 in aerobic glycolysis, viability and apoptosis in prostate cancer cells and probed the interaction between PCA3 and microRNA-1 (miR-1)/cyclin-dependent kinase 4 (CDK4). Here we found that PCA3 and CDK4 were up-regulated while miR-1 was down-regulated in prostate cancer tissues and cells. Moreover, knockdown of PCA3 inhibited aerobic glycolysis and viability and induced apoptosis in prostate cancer cells. Intriguingly, PCA3 was bound to miR-1 and inhibition of miR-1 reversed the regulatory effect of PCA3 knockdown on aerobic glycolysis, viability and apoptosis in prostate cancer cells. Besides, CDK4 was indicated as a target of miR-1 and it was regulated by PCA3 through functioning as a competing endogenous RNA (ceRNA) of miR-1 in prostate cancer cells. The results indicated that PCA3 might drive aerobic glycolysis, viability and apoptosis by regulating the miR-1/CDK4 axis in prostate cancer cells, providing a promising avenue for treatment of prostate cancer.
    Language English
    Publishing date 2018-11-08
    Publishing country England
    Document type Journal Article ; Retracted Publication
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/c8ra08083f
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: [Corrigendum] MicroRNA‑379‑5p plays a tumor‑suppressive role in human bladder cancer growth and metastasis by directly targeting MDM2.

    Wu, Deyao / Niu, Xiaobing / Tao, Jun / Li, Pengchao / Lu, Qiang / Xu, Aiming / Chen, Wei / Wang, Zengjun

    Oncology reports

    2022  Volume 48, Issue 5

    Abstract: Following the publication of the above article, an interested reader drew to the authors' attention that the cell and invasion migration assay data featured in Figs. 2C and 5D contained two pairs of overlapping panels, such that the data appeared to have ...

    Abstract Following the publication of the above article, an interested reader drew to the authors' attention that the cell and invasion migration assay data featured in Figs. 2C and 5D contained two pairs of overlapping panels, such that the data appeared to have been derived from the same original sources, even though the data panels were intending to show the results from differently performed experiments. Moreover, there was also an instance of duplicated data panels comparing between the si‑NC/cell invasion and si‑NC/cell migration assay panels in Fig. 4C. After having examined their original data, the authors have realized that inadvertent errors were made during the process of compiling these figures. Corrected versions of Figs. 2, 4 and 5, incorporating all the data from one of the repeated experiments, are shown opposite and on the next page. The authors all agree to the publication of this corrigendum, and are grateful to the Editor of
    Language English
    Publishing date 2022-09-21
    Publishing country Greece
    Document type Published Erratum
    ZDB-ID 1222484-4
    ISSN 1791-2431 ; 1021-335X
    ISSN (online) 1791-2431
    ISSN 1021-335X
    DOI 10.3892/or.2022.8413
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Prediction of natural fracture in shale oil reservoir based on R/S analysis and conventional logs

    Xu, Haoran / Ju, Wei / Niu, Xiaobing / Feng, Shengbin / You, Yuan / Yang, Hui / Liu, Sijia / Luan, Wenbo

    Frontiers of earth science. 2021 Sept., v. 15, no. 3

    2021  

    Abstract: Investigation into natural fractures is extremely important for the exploration and development of low-permeability reservoirs. Previous studies have proven that abundant oil resources are present in the Upper Triassic Yanchang Formation Chang 7 oil- ... ...

    Abstract Investigation into natural fractures is extremely important for the exploration and development of low-permeability reservoirs. Previous studies have proven that abundant oil resources are present in the Upper Triassic Yanchang Formation Chang 7 oil-bearing layer of the Ordos Basin, which are accumulated in typical low-permeability shale reservoirs. Natural fractures are important storage spaces and flow pathways for shale oil. In this study, characteristics of natural fractures in the Chang 7 oil-bearing layer are first analyzed. The results indicate that most fractures are shear fractures in the Heshui region, which are characterized by high-angle, unfilled, and ENE-WSW-trending strike. Subsequently, natural fracture distributions in the Yanchang Formation Chang 7 oil-bearing layer of the study area are predicted based on the R/S analysis approach. Logs of AC, CAL, ILD, LL8, and DEN are selected and used for fracture prediction in this study, and the R(n)/S(n) curves of each log are calculated. The quadratic derivatives are calculated to identify the concave points in the R(n)/S(n) curve, indicating the location where natural fracture develops. Considering the difference in sensitivity of each log to natural fracture, gray prediction analysis is used to construct a new parameter, fracture prediction indicator K, to quantitatively predict fracture development. In addition, fracture development among different wells is compared. The results show that parameter K responds well to fracture development. Some minor errors may probably be caused by the heterogeneity of the reservoir, limitation of core range and fracture size, dip angle, filling minerals, etc.
    Keywords Triassic period ; basins ; oil fields ; oils ; prediction ; shale
    Language English
    Dates of publication 2021-09
    Size p. 705-718.
    Publishing place Higher Education Press
    Document type Article
    Note Review
    ZDB-ID 2606749-3
    ISSN 2095-0209 ; 2095-0195
    ISSN (online) 2095-0209
    ISSN 2095-0195
    DOI 10.1007/s11707-020-0843-z
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  10. Article ; Online: SLC14A1 (UT-B) gene rearrangement in urothelial carcinoma of the bladder: a case report.

    Guo, Zhongying / Niu, Xiaobing / Fu, Guangbo / Yang, Baoxue / Chen, Guangping / Sun, Su'an

    Diagnostic pathology

    2020  Volume 15, Issue 1, Page(s) 94

    Abstract: Background: Bladder cancer (BC) is a common and deadly disease. Over the past decade, a number of genetic alterations have been reported in BC. Bladder urothelium expresses abundant urea transporter UT-B encoded by Slc14a1 gene at 18q12.3 locus, which ... ...

    Abstract Background: Bladder cancer (BC) is a common and deadly disease. Over the past decade, a number of genetic alterations have been reported in BC. Bladder urothelium expresses abundant urea transporter UT-B encoded by Slc14a1 gene at 18q12.3 locus, which plays an important role in preventing high concentrated urea-caused cell injury. Early genome-wide association studies (GWAS) showed that UT-B gene mutations are genetically linked to the urothelial bladder carcinoma (UBC). In this study, we examined whether Slc14a1 gene has been changed in UBC, which has never been reported.
    Case presentation: A 59-year-old male was admitted to a hospital with the complaint of gross hematuria for 6 days. Ultrasonography revealed a size of 2.8 × 1.7 cm mass lesion located on the rear wall and dome of the bladder. In cystoscopic examination, papillary tumoral lesions 3.0-cm in total diameter were seen on the left wall of the bladder and 2 cm to the left ureteric orifice. Transurethral resection of bladder tumor (TURBT) was performed. Histology showed high-grade non-muscle invasive UBC. Immunostaining was negative for Syn, CK7, CK20, Villin, and positive for HER2, BRCA1, GATA3. Using a fluorescence in situ hybridization (FISH), Slc14a1 gene rearrangement was identified by a pair of break-apart DNA probes.
    Conclusions: We for the first time report a patient diagnosed with urothelial carcinoma accompanied with split Slc14a1 gene abnormality, a crucial gene in bladder.
    MeSH term(s) Carcinoma in Situ/pathology ; Carcinoma, Transitional Cell/genetics ; Carcinoma, Transitional Cell/pathology ; Gene Rearrangement/genetics ; Humans ; Male ; Membrane Transport Proteins/genetics ; Middle Aged ; Urinary Bladder/pathology ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/pathology ; Urologic Neoplasms/genetics ; Urologic Neoplasms/pathology ; Urothelium/pathology ; Urea Transporters
    Chemical Substances Membrane Transport Proteins
    Language English
    Publishing date 2020-07-23
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2210518-9
    ISSN 1746-1596 ; 1746-1596
    ISSN (online) 1746-1596
    ISSN 1746-1596
    DOI 10.1186/s13000-020-01009-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top