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  1. Article ; Online: Circulating tumour cells and circulating cell-free DNA in patients with lung cancer

    Vladimir Anikin / Thomas Carter / Marcia Hall / Andreas Polychronis / Periklis Katopodis / Uday Kishore / Nizar Asadi / Emmanouil Karteris

    BMJ Open Respiratory Research, Vol 8, Iss

    a comparison between thoracotomy and video-assisted thoracoscopic surgery

    2021  Volume 1

    Keywords Medicine ; R ; Diseases of the respiratory system ; RC705-779
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Sternal resection and reconstruction for local recurrence of breast cancer using the sternal allograft transplantation technique.

    Dell'amore, Andrea / Nizar, Asadi / Dolci, Giampiero / Cassanelli, Nicola / Caroli, Guido / Luciano, Giulia / Greco, Domenico / Bini, Alessandro / Stella, Franco

    Heart, lung & circulation

    2013  Volume 22, Issue 3, Page(s) 234–238

    Abstract: Sternal involvement in patients with breast cancer is relatively rare and its treatment is still controversial. Surgery is usually indicated in cases of single metastases in a multimodality protocol. Partial or complete sternectomy associated or not with ...

    Abstract Sternal involvement in patients with breast cancer is relatively rare and its treatment is still controversial. Surgery is usually indicated in cases of single metastases in a multimodality protocol. Partial or complete sternectomy associated or not with the resection of surrounding tissues is the technique of choice to obtain safety margins and radical treatment of the disease. The most challenging part of the operation is the reconstruction of the anterior chest wall in order to avoid secondary complications and respiratory failure. In the last few years, different techniques and materials have been used to reconstruct the sternum. We report our experience in two patients with recurrent breast cancer using the sternal allograft technique to replace the sternum after partial sternectomy. The use of a sternal-allograft provides excellent functional and cosmetic results without complications during the follow-up period. The implantation technique is simple and reproducible.
    MeSH term(s) Bone Neoplasms/secondary ; Bone Neoplasms/surgery ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Carcinoma, Ductal, Breast/secondary ; Carcinoma, Ductal, Breast/surgery ; Female ; Humans ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local/surgery ; Reconstructive Surgical Procedures ; Sternum/pathology ; Sternum/surgery ; Sternum/transplantation ; Transplantation, Homologous
    Language English
    Publishing date 2013-03
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2012.07.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Can topical application of tranexamic acid reduce blood loss in thoracic surgery? A prospective randomised double blind investigation.

    Dell'Amore, Andrea / Caroli, Guido / Nizar, Asadi / Cassanelli, Nicola / Luciano, Giulia / Greco, Domenico / Dolci, Giampiero / Bini, Alessandro / Stella, Franco

    Heart, lung & circulation

    2012  Volume 21, Issue 11, Page(s) 706–710

    Abstract: Objective: The systemic or topical use of antifibrinolytic agents is effective in reducing postoperative bleeding and blood product transfusion in cardiac surgery. We sought to study the effect of the topical application of tranexamic acid into the ... ...

    Abstract Objective: The systemic or topical use of antifibrinolytic agents is effective in reducing postoperative bleeding and blood product transfusion in cardiac surgery. We sought to study the effect of the topical application of tranexamic acid into the pleural space to reduce postoperative bleeding after lung surgery.
    Methods: This was a prospective randomised double blind placebo controlled investigation. From May-2010 to February-2012, 89-patients, scheduled for pulmonary resection, were randomly allocated to one of the two study groups. Group-A received 5 g of tranexamic-acid in 100 ml of saline solution. Group-B received 100 ml of saline solution as placebo.
    Results: The blood loss in the first 12-h was significantly less in group-A. The same trend was observed in the first 24-h but without reaching a true statistical significance. The mean volume of blood transfusion was statistically lower in group-A. The analysis between post-operative haemoglobin concentration, haematocrit, platelet-count, international-normalised-ratio, fibrinogen and partial-thromboplastin-time of both groups was not statistically significant.
    Conclusion: In our experience, the topical use of tranexamic-acid after lung surgery reduces postoperative bleeding and blood transfusion volume. The topical administration of tranexamic-acid is safe without increasing the risk of post-operative complications related to pharmacological side-effects.
    MeSH term(s) Administration, Topical ; Aged ; Antifibrinolytic Agents/administration & dosage ; Antifibrinolytic Agents/adverse effects ; Blood Loss, Surgical/prevention & control ; Blood Transfusion ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Postoperative Hemorrhage/blood ; Postoperative Hemorrhage/prevention & control ; Prospective Studies ; Thoracic Surgery ; Tranexamic Acid/administration & dosage ; Tranexamic Acid/adverse effects
    Chemical Substances Antifibrinolytic Agents ; Tranexamic Acid (6T84R30KC1)
    Language English
    Publishing date 2012-11
    Publishing country Australia
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2012.06.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Desmoid tumour of the thoracic outlet in a 70 year-old man successfully removed through cervico-thoracic Dartevelle approach.

    Stella, Franco / Dell'amore, Andrea / Nizar, Asadi / Cassanelli, Nicola / Caroli, Guido / Luciano, Giulia / Greco, Domenico / Dolci, Giampiero / Pirini, Giulia / Bini, Alessandro

    Heart, lung & circulation

    2013  Volume 22, Issue 3, Page(s) 224–228

    Abstract: Desmoid tumours have a strong tendency for local invasion and recurrence. A 70 year-old male presented with cervical and left shoulder pain associated with a supraclavicular mass. The computed-tomography showed an expansive lesion measuring 10 cm × 6 cm × ...

    Abstract Desmoid tumours have a strong tendency for local invasion and recurrence. A 70 year-old male presented with cervical and left shoulder pain associated with a supraclavicular mass. The computed-tomography showed an expansive lesion measuring 10 cm × 6 cm × 5.5 cm in the left supraclavicular space. At magnetic resonance imaging the subclavian vessels and the brachial plexus were dislocated anteriorly but not infiltrated. An incisional biopsy suggested a desmoid tumour. An anterior cervicothoracic approach was used to remove the tumour. The chest wall was reconstructed with titanium bars and a polytetrafluoroethylene-patch. The clavicle was fixed using a titanium clip. The post-operative course was uneventful. The patient was treated with adjuvant radiation therapy. After six months the patient is in good clinical condition free from disease recurrence. In conclusion, desmoid tumour of the thoracic outlet is a challenging situation. Wide radical resection should be attempted whenever possible. The Dartevelle approach gives an optimal surgical field with direct control of vessels and nerve roots facilitating tumour dissection and radical resection en-bloc with the chest wall. The chest wall reconstruction with titanium bars and clips is a simple and effective method to guarantee good respiratory function and to stabilise the shoulder girdle.
    MeSH term(s) Aged ; Fibromatosis, Aggressive/diagnostic imaging ; Fibromatosis, Aggressive/pathology ; Fibromatosis, Aggressive/surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Thoracic Wall/pathology ; Thoracic Wall/surgery ; Tomography, X-Ray Computed
    Language English
    Publishing date 2013-03
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 2020980-0
    ISSN 1444-2892 ; 1443-9506
    ISSN (online) 1444-2892
    ISSN 1443-9506
    DOI 10.1016/j.hlc.2012.06.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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