Article ; Online: Genetic polymorphism of 27 Y-STR loci in Kazakh populations from Eastern Kazakhstan.
2023 Volume 50, Issue 1, Page(s) 48–51
Abstract: Background: The establishment of a national haplotype database is important for forensic and genetic applications and requires studying genetic polymorphisms at Y-STR sites. However, the genetic structure of the Eastern Kazakhstan population is poorly ... ...
Abstract | Background: The establishment of a national haplotype database is important for forensic and genetic applications and requires studying genetic polymorphisms at Y-STR sites. However, the genetic structure of the Eastern Kazakhstan population is poorly characterised. Aim: To investigate the genetic polymorphisms of 27 Y-STR loci in the Kazakh population from Eastern Kazakhstan and analyse the population genetic relationships of the Eastern Kazakhs with other populations. Subjects and methods: The Yfiler Plus kit was utilised to genotype 246 healthy, unrelated males from Eastern Kazakhstan. Based on the raw data, haplotype and allele frequencies along with forensic parameters were calculated, and an MDS plot was constructed. Results: A total of 207 haplotypes were detected, of which 186 were unique. The haplotype diversity and discrimination capacity were 0.997 and 0.841, respectively. Population comparisons showed that Eastern Kazakhs have close genetic relationships with Kazakhs from Xinjiang, China. At the same time, a difference was found between the studied population and the previous one in the same part of Kazakhstan. Conclusions: The obtained haplotypes will help to expand the Kazakhstan Y-chromosome reference database and will be useful for future genetic research and forensic applications. |
---|---|
MeSH term(s) | Male ; Humans ; Kazakhstan ; Microsatellite Repeats/genetics ; Chromosomes, Human, Y/genetics ; Polymorphism, Genetic ; Gene Frequency ; Genetics, Population ; Haplotypes ; China |
Language | English |
Publishing date | 2023-01-18 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 186656-4 |
ISSN | 1464-5033 ; 0301-4460 |
ISSN (online) | 1464-5033 |
ISSN | 0301-4460 |
DOI | 10.1080/03014460.2023.2170465 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
Zs.A 1019: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.