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  1. Artikel ; Online: Overabundance of sika deer and immunocontraception.

    Noguchi, Junko

    The Journal of reproduction and development

    2017  Band 63, Heft 1, Seite(n) 13–16

    Abstract: The impact of deer overabundance is a worldwide problem. Along with habitat expansion and population increase, damage by sika deer to the forest ecosystem and agriculture has become a serious issue in Japan. Deer also transmit a number of diseases and ... ...

    Abstract The impact of deer overabundance is a worldwide problem. Along with habitat expansion and population increase, damage by sika deer to the forest ecosystem and agriculture has become a serious issue in Japan. Deer also transmit a number of diseases and parasites to humans and livestock. The overabundance of deer is a result of their strong fecundity, and therefore the present situation should, in theory, be tackled by experts in reproductive biology.
    Mesh-Begriff(e) Animals ; Contraception, Immunologic/methods ; Deer/physiology ; Female ; Forests ; Freund's Adjuvant ; Japan ; Male ; Species Specificity ; Spermatogenesis ; Testis/physiology
    Chemische Substanzen Freund's Adjuvant (9007-81-2)
    Sprache Englisch
    Erscheinungsdatum 2017-02-16
    Erscheinungsland Japan
    Dokumenttyp Journal Article
    ISSN 1348-4400
    ISSN (online) 1348-4400
    DOI 10.1262/jrd.2016-132
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: A Community-engaged Curriculum at Alpert Medical School: Centering Patient Communities in Medical Education.

    Noguchi, Julia / Knopov, Anita / Bencie, Nicole / Mather, Thais Salazar / Chofay, Dana Ricci / Warrier, Sarita / Rougas, Steven

    Rhode Island medical journal (2013)

    2023  Band 106, Heft 9, Seite(n) 14–19

    Abstract: Background: Incorporating opportunities for community engagement into undergraduate medical education (UME) can help learners to identify and address social determinants of health (SDoH). Multiple challenges exist in operationalizing these experiences.!# ...

    Abstract Background: Incorporating opportunities for community engagement into undergraduate medical education (UME) can help learners to identify and address social determinants of health (SDoH). Multiple challenges exist in operationalizing these experiences.
    Methods: Using the Assessing Community Engagement (ACE) model, course directors at the Warren Alpert Medical School of Brown University (AMS) mapped community engagement initiatives to the four-year curriculum.
    Findings: Service-learning, community engagement projects, and clinical rotations at health centers and free clinics aim to equip learners at AMS with the necessary skills to address SDoH. Careful consideration should be given to the time and resources required to facilitate relationships with community-based agencies, learner reflection, program evaluation, and community-level outcomes.
    Conclusions: Community engagement activities should be aligned with learning objectives during the pre-clerkship and clerkship stages of the existing UME curricula. Embarking on a curriculum redesign can create opportunities to expand partnerships with local agencies and deepen student engagement.
    Mesh-Begriff(e) Humans ; Schools, Medical ; Curriculum ; Education, Medical ; Education, Medical, Undergraduate ; Ambulatory Care Facilities
    Sprache Englisch
    Erscheinungsdatum 2023-10-02
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 419430-5
    ISSN 2327-2228 ; 0363-7913
    ISSN (online) 2327-2228
    ISSN 0363-7913
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: 39 Efficacy of roscovitine and dibutyryl cAMP to block premature meiosis in porcine oocytes vitrified at the germinal vesicle stage and their effect on subsequent embryo development.

    Hiep, N / Somfai, T / Hirao, Y / Dang-Nguyen, T / Men, N / Linh, N / Nguyen, B / Noguchi, J / Kaneko, H / Kikuchi, K

    Reproduction, fertility, and development

    2022  Band 34, Heft 2, Seite(n) 254

    Sprache Englisch
    Erscheinungsdatum 2022-03-01
    Erscheinungsland Australia
    Dokumenttyp Journal Article
    ZDB-ID 1019913-5
    ISSN 1448-5990 ; 1031-3613
    ISSN (online) 1448-5990
    ISSN 1031-3613
    DOI 10.1071/RDv34n2Ab39
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Altered projection-specific synaptic remodeling and its modification by oxytocin in an idiopathic autism marmoset model.

    Noguchi, Jun / Watanabe, Satoshi / Oga, Tomofumi / Isoda, Risa / Nakagaki, Keiko / Sakai, Kazuhisa / Sumida, Kayo / Hoshino, Kohei / Saito, Koichi / Miyawaki, Izuru / Sugano, Eriko / Tomita, Hiroshi / Mizukami, Hiroaki / Watakabe, Akiya / Yamamori, Tetsuo / Ichinohe, Noritaka

    Communications biology

    2024  Band 7, Heft 1, Seite(n) 642

    Abstract: Alterations in the experience-dependent and autonomous elaboration of neural circuits are assumed to underlie autism spectrum disorder (ASD), though it is unclear what synaptic traits are responsible. Here, utilizing a valproic acid-induced ASD marmoset ... ...

    Abstract Alterations in the experience-dependent and autonomous elaboration of neural circuits are assumed to underlie autism spectrum disorder (ASD), though it is unclear what synaptic traits are responsible. Here, utilizing a valproic acid-induced ASD marmoset model, which shares common molecular features with idiopathic ASD, we investigate changes in the structural dynamics of tuft dendrites of upper-layer pyramidal neurons and adjacent axons in the dorsomedial prefrontal cortex through two-photon microscopy. In model marmosets, dendritic spine turnover is upregulated, and spines are generated in clusters and survived more often than in control marmosets. Presynaptic boutons in local axons, but not in commissural long-range axons, demonstrate hyperdynamic turnover in model marmosets, suggesting alterations in projection-specific plasticity. Intriguingly, nasal oxytocin administration attenuates clustered spine emergence in model marmosets. Enhanced clustered spine generation, possibly unique to certain presynaptic partners, may be associated with ASD and be a potential therapeutic target.
    Mesh-Begriff(e) Animals ; Oxytocin/metabolism ; Callithrix ; Disease Models, Animal ; Neuronal Plasticity ; Male ; Synapses/metabolism ; Dendritic Spines/metabolism ; Dendritic Spines/pathology ; Dendritic Spines/drug effects ; Autism Spectrum Disorder/metabolism ; Autistic Disorder/metabolism ; Autistic Disorder/pathology ; Prefrontal Cortex/metabolism ; Prefrontal Cortex/pathology ; Prefrontal Cortex/drug effects ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Valproic Acid/pharmacology ; Presynaptic Terminals/metabolism ; Female ; Axons/metabolism
    Chemische Substanzen Oxytocin (50-56-6) ; Valproic Acid (614OI1Z5WI)
    Sprache Englisch
    Erscheinungsdatum 2024-05-27
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-024-06345-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: My Life, My Story: Integrating a Life Story Narrative Component Into Medical Student Curricula.

    Lam, Jeffrey A / Feingold-Link, Mara / Noguchi, Julia / Quinn, Anne / Chofay, Dana / Cahill, Kate / Rougas, Steven

    MedEdPORTAL : the journal of teaching and learning resources

    2022  Band 18, Seite(n) 11211

    Abstract: Introduction: Medical students experience burnout, depersonalization, and decreases in empathy throughout medical training. My Life, My Story (MLMS) is a narrative medicine project that aims to combat these adverse outcomes by teaching students to ... ...

    Abstract Introduction: Medical students experience burnout, depersonalization, and decreases in empathy throughout medical training. My Life, My Story (MLMS) is a narrative medicine project that aims to combat these adverse outcomes by teaching students to interview patients about their life story, with the goal of improving patient-centered care competencies, such as empathy.
    Methods: The MLMS project was started in the Veterans Affairs (VA) system and has since spread to dozens of VA sites. We adapted and integrated this project into the Warren Alpert Medical School of Brown University curriculum. As part of the required curriculum, first- and third-year medical students participated in a life story interview with a community-based volunteer or a patient in the inpatient hospital setting, transcribed the story, and reviewed the written story with the patient. We assessed student perceptions of the project, changes in empathy, and changes in burnout symptoms.
    Results: A total of 240 students participated in this project. Students spent an average of 70.7 minutes interviewing patients. A majority of the students believed MLMS was a good use of time (77%), fostered connection with patients (79%), and was effective in recognizing patients' thoughts and feelings (69%).
    Discussion: To our knowledge, this is one of the first life story interview interventions to be implemented into a required medical school curriculum and outside the VA setting. MLMS may assist students in improving clinical empathy skills and create a structure for medical trainees to better understand their patients.
    Mesh-Begriff(e) Curriculum ; Empathy ; Humans ; Patient-Centered Care ; Schools, Medical ; Students, Medical
    Sprache Englisch
    Erscheinungsdatum 2022-01-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2374-8265
    ISSN (online) 2374-8265
    DOI 10.15766/mep_2374-8265.11211
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Donor-origin anaplastic lymphoma kinase driver-positive inflammatory myofibroblastic tumor after umbilical cord blood transplantation in pediatric acute lymphoblastic leukemia.

    Horiguchi, Ayumi / Arakawa, Yuki / Noguchi, Jun / Mori, Makiko / Oshima, Koichi / Iwama, Itaru / Kawashima, Hiroshi / Tanami, Yutaka / Nakazawa, Atsuko / Koh, Katsuyoshi

    Pediatric blood & cancer

    2022  Band 69, Heft 11, Seite(n) e29708

    Mesh-Begriff(e) Anaplastic Lymphoma Kinase ; Child ; Cord Blood Stem Cell Transplantation/adverse effects ; Hematopoietic Stem Cell Transplantation ; Humans ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy ; Tissue Donors
    Chemische Substanzen Anaplastic Lymphoma Kinase (EC 2.7.10.1)
    Sprache Englisch
    Erscheinungsdatum 2022-04-20
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.29708
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Developmental ability of oocytes retrieved from Meishan neonatal ovarian tissue grafted into nude mice.

    Kaneko, Hiroyuki / Kikuchi, Kazuhiro / Men, Nguyen Thi / Noguchi, Junko

    Animal science journal = Nihon chikusan Gakkaiho

    2019  Band 90, Heft 3, Seite(n) 344–352

    Abstract: Ovarian xenografting makes it possible to obtain oocytes with fertilization ability from immature pigs of Western breeds. In this study, we applied these methods to the Meishan, an indigenous Chinese pig breed, and investigated the developmental ... ...

    Abstract Ovarian xenografting makes it possible to obtain oocytes with fertilization ability from immature pigs of Western breeds. In this study, we applied these methods to the Meishan, an indigenous Chinese pig breed, and investigated the developmental competence of oocytes grown in their neonatal tissue after grafting into nude mice. First, mice harboring neonatal ovarian tissue were infused with follicle stimulating hormone (FSH) (62.5 U/ml) for 13 days starting at 10, 30, and 60 days after vaginal opening (D10-, D30-, and D60-FSH groups, respectively). Development of antral follicles and their oocytes was most enhanced in the D60-FSH group. For the next step, we examined the in vitro maturation ability of the oocytes recovered from host mice after infusion with FSH at a dose of 62.5 U/ml or 125 U/ml (FSH-62.5 or -125 group) for 13 days starting at 60 days after vaginal opening. Many more oocytes with maturation ability were obtained from the FSH-125 group. The FSH-125 mature oocytes were fertilized in vitro, as shown by formation of male and female pronuclei, but did not reach the blastocyst stage. These results indicate that Meishan neonatal ovaries are able to produce oocytes with fertilization ability after being grafted into nude mice.
    Mesh-Begriff(e) Animals ; Animals, Newborn ; Female ; Fertilization ; Fertilization in Vitro ; Follicle Stimulating Hormone/administration & dosage ; Heterografts ; In Vitro Oocyte Maturation Techniques ; Male ; Mice, Nude ; Oocytes/growth & development ; Oocytes/physiology ; Oocytes/transplantation ; Ovary/cytology ; Swine ; Time Factors
    Chemische Substanzen Follicle Stimulating Hormone (9002-68-0)
    Sprache Englisch
    Erscheinungsdatum 2019-01-17
    Erscheinungsland Australia
    Dokumenttyp Journal Article
    ZDB-ID 2095161-9
    ISSN 1740-0929 ; 1344-3941
    ISSN (online) 1740-0929
    ISSN 1344-3941
    DOI 10.1111/asj.13160
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Buch ; Online: Nevanlinna theory in several complex variables and diophantine approximation

    Noguchi, Junjiro / Winkelmann, Jörg

    (Grundlehren der mathematischen Wissenschaften, A Series of Comprehensive Studies in Mathematics ; 350)

    2014  

    Abstract: The aim of this book is to provide a comprehensive account of higher dimensional Nevanlinna theory and its relations with Diophantine approximation theory for graduate students and interested researchers. This book with nine chapters systematically ... ...

    Verfasserangabe Junjiro Noguchi; Jörg Winkelmann
    Serientitel Grundlehren der mathematischen Wissenschaften, A Series of Comprehensive Studies in Mathematics ; 350
    Abstract The aim of this book is to provide a comprehensive account of higher dimensional Nevanlinna theory and its relations with Diophantine approximation theory for graduate students and interested researchers. This book with nine chapters systematically describes Nevanlinna theory of meromorphic maps between algebraic varieties or complex spaces, building up from the classical theory of meromorphic functions on the complex plane with full proofs in Chap. 1 to the current state of research. Chapter 2 presents the First Main Theorem for coherent ideal sheaves in a very general form. With the preparation of plurisubharmonic functions, how the theory to be generalized in a higher dimension is described. In Chap. 3 the Second Main Theorem for differentiably non-degenerate meromorphic maps by Griffiths and others is proved as a prototype of higher dimensional Nevanlinna theory. Establishing such a Second Main Theorem for entire curves in general complex algebraic varieties is a wide-open problem. In Chap. 4, the Cartan-Nochka Second Main Theorem in the linear projective case and the Logarithmic Bloch-Ochiai Theorem in the case of general algebraic varieties are proved. Then the theory of entire curves in semi-abelian varieties, including the Second Main Theorem of Noguchi-Winkelmann-Yamanoi, is dealt with in full details in Chap. 6. For that purpose Chap. 5 is devoted to the notion of semi-abelian varieties. The result leads to a number of applications. With these results, the Kobayashi hyperbolicity problems are discussed in Chap. 7. In the last two chapters Diophantine approximation theory is dealt with from the viewpoint of higher dimensional Nevanlinna theory, and the Lang-Vojta conjecture is confirmed in some cases. In Chap. 8 the theory over function fields is discussed. Finally, in Chap. 9, the theorems of Roth, Schmidt, Faltings, and Vojta over number fields are presented and formulated in view of Nevanlinna theory with results motivated by those in Chaps. 4, 6, and 7
    Schlagwörter Differential equations, partial ; Functions of complex variables ; Geometry, algebraic ; Mathematics ; Number theory ; Technik / Wissen Mathematik
    Sprache Englisch
    Umfang Online-Ressource (XIV, 416 p. 6 illus)
    Verlag Springer
    Erscheinungsort Tokyo u.a.
    Dokumenttyp Buch ; Online
    Anmerkung Description based upon print version of record
    ISBN 9784431545705 ; 9784431545712 ; 4431545700 ; 4431545719
    DOI 10.1007/978-4-431-54571-2
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  9. Buch: Nevanlinna theory in several complex variables and diophantine approximation

    Noguchi, Junjiro / Winkelmann, Jörg

    (Grundlehren der mathematischen Wissenschaften ; 350)

    2014  

    Verfasserangabe Junjiro Noguchi; Jörg Winkelmann
    Serientitel Grundlehren der mathematischen Wissenschaften ; 350
    Sprache Englisch
    Umfang XIV, 416 S., 235 mm x 155 mm
    Verlag Springer
    Erscheinungsort Tokyo u.a.
    Dokumenttyp Buch
    Anmerkung Literaturverz. S. 393 - 410
    ISBN 9784431545705 ; 9784431545712 ; 4431545700 ; 4431545719
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  10. Buch: Nevanlinna theory in several complex variables and diophantine approximation

    Noguchi, Junjiro / Winkelmann, Jörg

    (Grundlehren der mathematischen Wissenschaften ; 350)

    2014  

    Verfasserangabe Junjiro Noguchi; Jörg Winkelmann
    Serientitel Grundlehren der mathematischen Wissenschaften ; 350
    Sprache Englisch
    Umfang XIV, 416 S., 235 mm x 155 mm
    Verlag Springer
    Erscheinungsort Tokyo u.a.
    Dokumenttyp Buch
    Anmerkung Literaturverz. S. 393 - 410
    ISBN 9784431545705 ; 9784431545712 ; 4431545700 ; 4431545719
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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