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  1. Article: Harmonic memory signals in the human cerebral cortex induced by semantic relatedness of words.

    Noguchi, Yasuki

    NPJ science of learning

    2024  Volume 9, Issue 1, Page(s) 6

    Abstract: When we memorize multiple words simultaneously, semantic relatedness among those words assists memory. For example, the information about "apple", "banana," and "orange" will be connected via a common concept of "fruits" and become easy to retain and ... ...

    Abstract When we memorize multiple words simultaneously, semantic relatedness among those words assists memory. For example, the information about "apple", "banana," and "orange" will be connected via a common concept of "fruits" and become easy to retain and recall. Neural mechanisms underlying this semantic integration in verbal working memory remain unclear. Here I used electroencephalography (EEG) and investigated neural signals when healthy human participants memorized five nouns semantically related (Sem trial) or not (NonSem trial). The regularity of oscillatory signals (8-30 Hz) during the retention period was found to be lower in NonSem than Sem trials, indicating that memorizing words unrelated to each other induced a non-harmonic (irregular) waveform in the temporal cortex. These results suggest that (i) semantic features of a word are retained as a set of neural oscillations at specific frequencies and (ii) memorizing words sharing a common semantic feature produces harmonic brain responses through a resonance or integration (sharing) of the oscillatory signals.
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article
    ISSN 2056-7936
    ISSN 2056-7936
    DOI 10.1038/s41539-024-00221-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Audio-Visual Fission Illusion and Individual Alpha Frequency: Perspective on Buergers and Noppeney (2022).

    Noguchi, Yasuki

    Journal of cognitive neuroscience

    2023  Volume 36, Issue 4, Page(s) 700–705

    Abstract: Integrating visual and auditory information is an important ability in various cognitive processes, although its neural mechanisms remain unclear. Several studies indicated a close relationship between one's temporal binding window (TBW) for audio-visual ...

    Abstract Integrating visual and auditory information is an important ability in various cognitive processes, although its neural mechanisms remain unclear. Several studies indicated a close relationship between one's temporal binding window (TBW) for audio-visual interaction and their alpha rhythm in the brain (individual alpha frequency or IAF). A recent study by Buergers and Noppeney [Buergers, S., & Noppeney, U. The role of alpha oscillations in temporal binding within and across the senses. Nature Human Behaviour, 6, 732-742, 2022], however, challenged this view using a new approach to analyze behavioral data. Conforming to the same procedures by Buergers and Noppeney, here, I analyzed the data of my previous study and examined a relationship between TBW and IAF. In contrast to Buergers and Noppeney, a significant correlation was found between occipital IAF and a new behavioral measure of TBW. Some possibilities that caused these opposing results, such as a variability of "alpha band" across studies and a large inter-individual difference in magnitude of the fission illusion, are discussed.
    MeSH term(s) Humans ; Illusions ; Visual Perception ; Brain ; Alpha Rhythm ; Photic Stimulation/methods
    Language English
    Publishing date 2023-03-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1007410-7
    ISSN 1530-8898 ; 0898-929X ; 1096-8857
    ISSN (online) 1530-8898
    ISSN 0898-929X ; 1096-8857
    DOI 10.1162/jocn_a_01987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2623: Show issues Location:
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  3. Article ; Online: Comment on: "A Disproportionality Analysis of Drug-Drug Interactions of Tizanidine and CYP1A2 Inhibitors from the FDA Adverse Event Reporting System (FAERS)".

    Noguchi, Yoshihiro

    Drug safety

    2022  Volume 45, Issue 12, Page(s) 1551–1552

    MeSH term(s) United States ; Humans ; Cytochrome P-450 CYP1A2 Inhibitors ; United States Food and Drug Administration ; Adverse Drug Reaction Reporting Systems ; Drug Interactions ; Cytochrome P-450 CYP1A2
    Chemical Substances Cytochrome P-450 CYP1A2 Inhibitors ; tizanidine (6AI06C00GW) ; CYP1A2 protein, human (EC 1.14.14.1) ; Cytochrome P-450 CYP1A2 (EC 1.14.14.1)
    Language English
    Publishing date 2022-10-12
    Publishing country New Zealand
    Document type Letter ; Comment
    ZDB-ID 1018059-x
    ISSN 1179-1942 ; 0114-5916
    ISSN (online) 1179-1942
    ISSN 0114-5916
    DOI 10.1007/s40264-022-01240-w
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    Zs.A 2127: Show issues Location:
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  4. Article ; Online: Comment on: "Drug-Drug Interaction of the Sodium Glucose Co-transporter 2 Inhibitors with Statins and Myopathy: A Disproportionality Analysis Using Adverse Events Reporting Data".

    Noguchi, Yoshihiro

    Drug safety

    2022  Volume 45, Issue 7, Page(s) 809–811

    MeSH term(s) Adverse Drug Reaction Reporting Systems ; Drug Interactions ; Glucose ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Muscular Diseases/chemically induced ; Sodium ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects ; Symporters
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Sodium-Glucose Transporter 2 Inhibitors ; Symporters ; Sodium (9NEZ333N27) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-06-17
    Publishing country New Zealand
    Document type Letter ; Comment
    ZDB-ID 1018059-x
    ISSN 1179-1942 ; 0114-5916
    ISSN (online) 1179-1942
    ISSN 0114-5916
    DOI 10.1007/s40264-022-01191-2
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    Zs.A 2127: Show issues Location:
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  5. Article ; Online: Individual differences in beta frequency correlate with the audio-visual fusion illusion.

    Noguchi, Yasuki

    Psychophysiology

    2022  Volume 59, Issue 8, Page(s) e14041

    Abstract: Presenting one flash with two beeps induces a perception of two flashes (audio-visual [AV] fission illusion), while presenting two flashes with one beep induces a perception of one flash (fusion illusion). Although previous studies showed a relationship ... ...

    Abstract Presenting one flash with two beeps induces a perception of two flashes (audio-visual [AV] fission illusion), while presenting two flashes with one beep induces a perception of one flash (fusion illusion). Although previous studies showed a relationship between the frequency of the alpha rhythm (alpha cycle) and one's susceptibility to the fission illusion, the relationship between neural oscillations and the fusion illusion is unknown. Using electroencephalography, here I investigated the frequency of oscillatory signals in the pre-stimulus period and found a significant correlation between the beta rhythm and the fusion illusion; specifically, participants with a lower beta frequency showed a larger fusion illusion. These data indicate two separate time windows of AV integration in the human brain, one defined by the alpha cycle (fission) and another defined by the beta cycle (fusion).
    MeSH term(s) Acoustic Stimulation ; Auditory Perception ; Humans ; Illusions ; Individuality ; Photic Stimulation ; Visual Perception
    Language English
    Publishing date 2022-03-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209486-1
    ISSN 1540-5958 ; 0048-5772
    ISSN (online) 1540-5958
    ISSN 0048-5772
    DOI 10.1111/psyp.14041
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    Zs.A 502: Show issues Location:
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  6. Article ; Online: Detection Algorithms for Simple Two-Group Comparisons Using Spontaneous Reporting Systems.

    Noguchi, Yoshihiro / Yoshimura, Tomoaki

    Drug safety

    2024  

    Abstract: Medical science has often used adult males as the standard to establish pathological conditions, their transitions, diagnostic methods, and treatment methods. However, it has recently become clear that sex differences exist in how risk factors contribute ...

    Abstract Medical science has often used adult males as the standard to establish pathological conditions, their transitions, diagnostic methods, and treatment methods. However, it has recently become clear that sex differences exist in how risk factors contribute to the same disease, and these differences also exist in the efficacy of the same drug. Furthermore, the elderly and children have lower metabolic functions than adult males, and the results of clinical trials on adult males cannot be directly applied to these patients. Spontaneous reporting systems have become an important source of information for safety assessment, thereby reflecting drugs' actual use in specific populations and clinical settings. However, spontaneous reporting systems only register drug-related adverse events (AEs); thus, they cannot accurately capture the total number of patients using these drugs. Therefore, although various algorithms have been developed to exploit disproportionality and search for AE signals, there is no systematic literature on how to detect AE signals specific to the elderly and children or sex-specific signals. This review describes signal detection using data mining, considering traditional methods and the latest knowledge, and their limitations.
    Language English
    Publishing date 2024-02-22
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 1018059-x
    ISSN 1179-1942 ; 0114-5916
    ISSN (online) 1179-1942
    ISSN 0114-5916
    DOI 10.1007/s40264-024-01404-w
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    Zs.A 2127: Show issues Location:
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  7. Article ; Online: Exciton maps for thermally activated delayed fluorescence active/inactive carbazole benzonitrile derivatives.

    Noguchi, Yoshifumi

    The Journal of chemical physics

    2021  Volume 155, Issue 20, Page(s) 204302

    Abstract: The all-electron first-principles GW+Bethe-Salpeter method was applied to six carbazole benzonitrile (CzBN) derivatives, which were recently reported to be both thermally activated delayed fluorescence (TADF) active and inactive despite their singlet- ... ...

    Abstract The all-electron first-principles GW+Bethe-Salpeter method was applied to six carbazole benzonitrile (CzBN) derivatives, which were recently reported to be both thermally activated delayed fluorescence (TADF) active and inactive despite their singlet-triplet splittings being commonly around 0.2 eV. The present method successfully reproduced very similar photoabsorption spectra as experiments from the viewpoint of the peak positions and relative peak heights. We also performed exciton analysis with the exciton wave functions for several lowest singlet and triplet exciton states to reveal the details of the optical properties. We applied this to not only the present six CzBN derivatives but also 18 other TADF molecules and proposed a new exciton map to classify the molecules as the TADF active/inactive by using the exciton binding energy in the vertical axis and the ratio of electron and hole delocalization in the horizontal axis. Our results suggest two possible TADF mechanisms: spatially less localized hole states than the electron states where the exciton binding energy is proportional to the ratio of hole and electron delocalization and spatially more localized hole states than the electron states where the exciton binding energy should be large.
    Language English
    Publishing date 2021-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0068402
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  8. Article ; Online: Comment on: Exploring the impact of design criteria for reference sets on performance evaluation of signal detection algorithms: The case of drug-drug interactions.

    Noguchi, Yoshihiro / Yoshimura, Tomoaki

    Pharmacoepidemiology and drug safety

    2023  Volume 33, Issue 1, Page(s) e5722

    MeSH term(s) Humans ; Drug Interactions ; Algorithms
    Language English
    Publishing date 2023-11-09
    Publishing country England
    Document type Letter
    ZDB-ID 1099748-9
    ISSN 1099-1557 ; 1053-8569
    ISSN (online) 1099-1557
    ISSN 1053-8569
    DOI 10.1002/pds.5722
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    Zs.A 3395: Show issues Location:
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  9. Article ; Online: Is it possible to identify risk factors for adverse drug reactions using a pharmacovigilance database based on spontaneous reporting?

    Noguchi, Yoshihiro / Yoshimura, Tomoaki

    Pharmacoepidemiology and drug safety

    2023  Volume 33, Issue 1, Page(s) e5737

    MeSH term(s) Humans ; Pharmacovigilance ; Drug-Related Side Effects and Adverse Reactions/epidemiology ; Drug-Related Side Effects and Adverse Reactions/etiology ; Databases, Factual ; Risk Factors ; Adverse Drug Reaction Reporting Systems
    Language English
    Publishing date 2023-11-20
    Publishing country England
    Document type Letter
    ZDB-ID 1099748-9
    ISSN 1099-1557 ; 1053-8569
    ISSN (online) 1099-1557
    ISSN 1053-8569
    DOI 10.1002/pds.5737
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  10. Article ; Online: Comment on: "Drug-associated kidney injury in children: a disproportionality analysis of the FDA adverse event reporting system".

    Noguchi, Yoshihiro / Yoshimura, Tomoaki

    European journal of pediatrics

    2023  Volume 183, Issue 2, Page(s) 975–976

    MeSH term(s) Child ; Humans ; United States/epidemiology ; Adverse Drug Reaction Reporting Systems ; Kidney ; Pharmacovigilance ; Databases, Factual
    Language English
    Publishing date 2023-12-04
    Publishing country Germany
    Document type Letter
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-023-05265-w
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