Article ; Online: Determinants of Adherence to Antihypertension Medications Among Patients at a Tertiary Care Hospital in Islamabad, Pakistan, 2019.
2023 Volume 20, Page(s) E42
Abstract: Introduction: Medication nonadherence leads to poor health outcomes, frequent complications, and high economic impact. Our objective was to assess the determinants of adherence to medication regimens among patients with hypertension.: Methods: We ... ...
| Abstract | Introduction: Medication nonadherence leads to poor health outcomes, frequent complications, and high economic impact. Our objective was to assess the determinants of adherence to medication regimens among patients with hypertension. Methods: We conducted a cross-sectional study of patients with hypertension attending the cardiology clinic of a tertiary care hospital in Islamabad, Pakistan. Data were collected by using semistructured questionnaires. A score of 7 or 8 on the 8-item Morisky Medication Adherence Scale was classified as good adherence, 6 as moderate, and less than 6 as nonadherence. Logistic regression was performed to determine covariates associated with medication adherence. Results: We enrolled 450 patients with hypertension (mean age, 54.5 y; SD, 10.6). Medication adherence was good among 115 (25.6%) patients and moderate among 165 (36.7%); 170 (37.8%) patients were nonadherent. Most patients (72.7%) had uncontrolled hypertension. Nearly half (49.6%) were unable to afford monthly medication. In bivariate analysis, nonadherence was associated with female sex (odds ratio [OR], 1.44; P = .003) and long waiting times in the health care facility (OR, 2.93; P = .005); the presence of comorbidities (OR, 0.62; P = .01) was associated with good adherence. In multivariate analysis, nonadherence was associated with unaffordability of treatment (OR, 2.25; P = .002) and uncontrolled hypertension (OR, 3.16; P < .001). Good adherence determinants included adequate counseling (OR, 0.29; P < .001) and education (OR, 0.61; P = .02). Conclusion: Addressing identified barriers, including medication affordability and patient counseling, should be included in Pakistan's national policy on noncommunicable disease. |
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| MeSH term(s) | Humans ; Female ; Middle Aged ; Tertiary Care Centers ; Pakistan ; Cross-Sectional Studies ; Antihypertensive Agents/therapeutic use ; Hypertension/drug therapy ; Hypertension/epidemiology ; Hypertension/psychology ; Medication Adherence |
| Chemical Substances | Antihypertensive Agents |
| Language | English |
| Publishing date | 2023-05-25 |
| Publishing country | United States |
| Document type | Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 2135684-1 |
| ISSN | 1545-1151 ; 1545-1151 |
| ISSN (online) | 1545-1151 |
| ISSN | 1545-1151 |
| DOI | 10.5888/pcd20.220231 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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