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  1. Article: Prevalence of alcohol consumption among clients of opioid agonist treatment (OAT) centers in Golestan province, Iran.

    Noroozi, Alireza / Danesh, Ahmad

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1134683

    Abstract: Introduction: Opioid agonist treatments (OATs) with methadone and buprenorphine are known to be effective treatments for people with opioid use disorder (OUD). However, concomitant use of other substances such as alcohol can negatively affect OAT ... ...

    Abstract Introduction: Opioid agonist treatments (OATs) with methadone and buprenorphine are known to be effective treatments for people with opioid use disorder (OUD). However, concomitant use of other substances such as alcohol can negatively affect OAT outcomes. This study aimed to determine the prevalence of alcohol use among clients of OAT centers in the Golestan province in the northern part of Iran.
    Materials and methods: This is a secondary analysis of a sample of 706 clients who were receiving OATs from certified OAT centers in Golestan province in 2015. They had been on OATs for at least 1 month and were randomly selected for the study. Data were collected via interviews with selected OAT clients. The main indicators studied in the present study were lifetime history of alcohol consumption, alcohol consumption during last month, lifetime history of excessive alcohol use on one occasion, and years of regular alcohol consumption.
    Results: The prevalence of lifetime history of alcohol consumption was estimated at 39.2%. Prevalence of alcohol consumption during last month and lifetime history of excessive alcohol use on one occasion was 6.9 and 18.8%, respectively.
    Conclusion: Despite a total ban on alcohol consumption in Iran, a sub-sample of participants admitted past-month alcohol use concurrent with their OATs. The estimated past-month prevalence of alcohol use was lower than the reported prevalence in countries where the production, distribution, and consumption of alcohol are legal.
    Language English
    Publishing date 2023-05-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1134683
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Editorial: Alcohol and drug use in low- and middle-income countries.

    El Hayek, Samer / Lasebikan, Victor / Noroozi, Alireza

    Frontiers in psychiatry

    2024  Volume 15, Page(s) 1381726

    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2024.1381726
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Commentary on Nikoo et al.: Challenges in protocol development to optimize outcomes of opium tincture maintenance treatment.

    Noroozi, Alireza / Rahimi-Movaghar, Afarin

    Addiction (Abingdon, England)

    2022  Volume 118, Issue 2, Page(s) 295–296

    MeSH term(s) Humans ; Opium/therapeutic use ; Methadone ; Morphine ; Research Design
    Chemical Substances Opium (8008-60-4) ; Methadone (UC6VBE7V1Z) ; Morphine (76I7G6D29C)
    Language English
    Publishing date 2022-12-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1141051-6
    ISSN 1360-0443 ; 0965-2140
    ISSN (online) 1360-0443
    ISSN 0965-2140
    DOI 10.1111/add.16106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Drug policies and responses in Afghanistan.

    Noroozi, Alireza / De Lara, Manuel / Abouzeid, Alaa

    The lancet. Psychiatry

    2023  Volume 11, Issue 2, Page(s) 90–91

    MeSH term(s) Humans ; Afghanistan ; Public Policy
    Language English
    Publishing date 2023-12-12
    Publishing country England
    Document type Journal Article
    ISSN 2215-0374
    ISSN (online) 2215-0374
    DOI 10.1016/S2215-0366(23)00390-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cryoablation for the Palliation of Painful Bone Metastasis: A Systematic Review.

    Khanmohammadi, Shaghayegh / Noroozi, Alireza / Yekaninejad, Mir Saeed / Rezaei, Nima

    Cardiovascular and interventional radiology

    2023  Volume 46, Issue 11, Page(s) 1469–1482

    Abstract: Background: Cryoablation is a minimally invasive procedure to treat painful bone metastases in patients with cancer. We designed a systematic review to understand the safety and effects of cryoablation on the pain and quality of life (QoL) of cancer ... ...

    Abstract Background: Cryoablation is a minimally invasive procedure to treat painful bone metastases in patients with cancer. We designed a systematic review to understand the safety and effects of cryoablation on the pain and quality of life (QoL) of cancer patients.
    Method: We searched PubMed, ISI, Cochrane library, and Scopus databases using the keywords "Cryoablation," "Pain," and "Bone metastasis." Inclusion criteria were: (1) Original studies published until September 8, 2022; (2) studies on patients over 18 years and affected by bone metastasis; (3) bone metastasis treated with stand-alone cryoablation; (4) studies reporting patients' pain before and at least one time-point following cryoablation; and (5) English-language studies.
    Results: We screened 696 articles. Fifteen studies on 376 patients were included. Time points for pain assessment ranged from 1 day to 6 months. Spine was the most frequent treated location. All studies reported a significant pain reduction between 1 day and 6 months after the cryoablation procedure. The highest mean difference between pre- and post-procedure scores was 5.8 (VAS scale) after 4 weeks. The overall rate of minor and major complications was 12.74%. Cryoablation improved the QoL of cancer patients and decreased the need for analgesics.
    Conclusion: Cryoablation is a safe and useful procedure for palliating painful bone metastasis and increasing the QoL of cancer patients. Future studies should adopt a standardized pain reporting scale to allow for meta-analysis.
    MeSH term(s) Humans ; Bone Neoplasms/surgery ; Bone Neoplasms/secondary ; Cryosurgery/methods ; Pain/etiology ; Quality of Life ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-022-03356-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Identification of the socio-cultural barriers of drug addiction treatment in Iran

    Razaghi, Emran / Farhoudian, Ali / Pilevari, Azam / Noroozi, Alireza / Hooshyari, Zahra / Radfar, Ramin / Malekinejad, Mohsen

    Heliyon. 2023 May, v. 9, no. 5 p.e15566-

    2023  

    Abstract: Socio-cultural norms can either be encouraging or a barrier to addiction treatment. More, rigorous research is needed on nonindigenous models in addiction treatment, to better understand the role of socio-cultural differences. The present qualitative ... ...

    Abstract Socio-cultural norms can either be encouraging or a barrier to addiction treatment. More, rigorous research is needed on nonindigenous models in addiction treatment, to better understand the role of socio-cultural differences. The present qualitative study is part of the project, "The Inclusive Assessment of the Barriers of Drug Addiction Treatment Services in Iran," which was conducted in Tehran from 2018 to 2021. The participants consisted of eight people who used drugs, seven individual family members of the people who used drugs participants, seven service providers, and four policymakers. A purposeful sampling method was used for the selection of the participants, and the process continued until reaching the theoretical saturation of data. Analysis used the Graneheim and Lundman methods, classifying primary codes, the sub-themes, and themes were classified according to the similarities and differences between primary codes. The most important socio-cultural barriers to addiction treatment in Iran are: unrealistic expectations of the family and society from the people who use drugs, addiction stigma, mistrust between various components of the treatment system, perceptions that professional substance use disorder treatment is inefficient and low uptake of that treatment, the disturbed relational boundaries between the people who use drugs and their relatives, the interweaving of treatment and ethical and religious principles, low acceptance of maintenance treatments, treatment focusing on short-term outcomes, and presence of facilitating backgrounds of using drugs. The Iranian socio-cultural characteristics play an important role in the addiction treatment of the people who use drugs, so it is necessary for treatment interventions to be sensitive to these characteristics.
    Keywords drug abuse ; ethics ; people ; qualitative analysis ; society ; stigma ; Iran ; Qualitative study ; Barriers ; Substance-related disorders ; Treatment
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e15566
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Identification of the socio-cultural barriers of drug addiction treatment in Iran.

    Razaghi, Emran / Farhoudian, Ali / Pilevari, Azam / Noroozi, Alireza / Hooshyari, Zahra / Radfar, Ramin / Malekinejad, Mohsen

    Heliyon

    2023  Volume 9, Issue 5, Page(s) e15566

    Abstract: Introduction: Socio-cultural norms can either be encouraging or a barrier to addiction treatment. More, rigorous research is needed on nonindigenous models in addiction treatment, to better understand the role of socio-cultural differences.: Methods: ...

    Abstract Introduction: Socio-cultural norms can either be encouraging or a barrier to addiction treatment. More, rigorous research is needed on nonindigenous models in addiction treatment, to better understand the role of socio-cultural differences.
    Methods: The present qualitative study is part of the project, "The Inclusive Assessment of the Barriers of Drug Addiction Treatment Services in Iran," which was conducted in Tehran from 2018 to 2021. The participants consisted of eight people who used drugs, seven individual family members of the people who used drugs participants, seven service providers, and four policymakers. A purposeful sampling method was used for the selection of the participants, and the process continued until reaching the theoretical saturation of data. Analysis used the Graneheim and Lundman methods, classifying primary codes, the sub-themes, and themes were classified according to the similarities and differences between primary codes.
    Finding: The most important socio-cultural barriers to addiction treatment in Iran are: unrealistic expectations of the family and society from the people who use drugs, addiction stigma, mistrust between various components of the treatment system, perceptions that professional substance use disorder treatment is inefficient and low uptake of that treatment, the disturbed relational boundaries between the people who use drugs and their relatives, the interweaving of treatment and ethical and religious principles, low acceptance of maintenance treatments, treatment focusing on short-term outcomes, and presence of facilitating backgrounds of using drugs.
    Conclusions: The Iranian socio-cultural characteristics play an important role in the addiction treatment of the people who use drugs, so it is necessary for treatment interventions to be sensitive to these characteristics.
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e15566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Management of gabapentin misuse in a patient with previous history of opioid use disorder: Case report.

    Jalilian Khave, Laya / Noori, Mehri / Rahimi-Movaghar, Afarin / Noroozi, Alireza

    Asian journal of psychiatry

    2022  Volume 80, Page(s) 103322

    Abstract: We present a 37-year-old male who misuses 12 g of gabapentin per day associated with dependence and withdrawal. He had a previous history of opioid use disorder (OUD) which has been in remission. An outpatient gradual dose reduction regimen was tried and ...

    Abstract We present a 37-year-old male who misuses 12 g of gabapentin per day associated with dependence and withdrawal. He had a previous history of opioid use disorder (OUD) which has been in remission. An outpatient gradual dose reduction regimen was tried and failed and the patient decided to discontinue gabapentin abruptly. Symptomatic medication to relieve gabapentin withdrawal was also unsuccessful and resulted in the reinstatement of OUD. Finally, the patient was stabilized using buprenorphine maintenance treatment and discontinued opioids and gabapentin misuse. The clinical implications and significance of taking regulatory actions to control gabapentin misuse have been discussed.
    MeSH term(s) Male ; Humans ; Adult ; Gabapentin/therapeutic use ; Opioid-Related Disorders/complications ; Opioid-Related Disorders/drug therapy ; Analgesics, Opioid/adverse effects ; Buprenorphine/therapeutic use
    Chemical Substances Gabapentin (6CW7F3G59X) ; Analgesics, Opioid ; Buprenorphine (40D3SCR4GZ)
    Language English
    Publishing date 2022-11-12
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2022.103322
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Blended smartphone intervention for patients in opioid maintenance treatment in Iran: protocol for a randomized controlled trial.

    Boumparis, Nikolaos / Noroozi, Alireza / Naghizadeh, Eisa / Meyer, Andreas / Wenger, Andreas / Rahimi-Movaghar, Afarin / Schaub, Michael P

    BMC psychiatry

    2023  Volume 23, Issue 1, Page(s) 518

    Abstract: Background: The pattern of substance use in Iran is characterized by a high prevalence of opioid use and opioid use disorder (OUD). Although opioid maintenance therapy (OMT) has been introduced in Iran, approximately 50% of people with opioid use ... ...

    Abstract Background: The pattern of substance use in Iran is characterized by a high prevalence of opioid use and opioid use disorder (OUD). Although opioid maintenance therapy (OMT) has been introduced in Iran, approximately 50% of people with opioid use disorder remain unreached. Moreover, psychosocial treatment of OUD and common mental health symptoms during OMT is limited. Digital interventions have been shown to improve psychological distress, depression, anxiety, and post-traumatic stress disorder symptoms. In addition, providing psychoeducation and risk reduction counseling to prevent communicable diseases like HIV and infectious hepatitis is common via the Internet. However, despite these promising advances, no smartphone intervention in OMT has been investigated for the treatment of OUD and common comorbid mental health symptoms.
    Objective: We examine the effectiveness of adding a blended smartphone intervention based on community reinforcement approach, motivational interviewing- and cognitive behavioral therapy compared to OMT as usual that aims to improve OMT outcomes and addresses common mental health symptoms in OMT patients in Iran.
    Method: Adults with opioid dependence entering 8 treatment centers in Tehran, Iran will be randomly assigned to receive either OMT plus a smartphone intervention or OMT as usual. The primary outcomes will be the percentage of negative urine tests for illicit, non-prescribed use of opioids (opium, heroin, tramadol) and treatment retention. Secondary outcomes will include the longest period of abstinence from the illicit, non-prescribed use of opioids (opium, heroin, and tramadol) confirmed by urine samples, changes in communicable disease risk-taking behaviors, changes in stress and common mental health symptoms, and client satisfaction. Data analysis will follow the intention-to-treat principle and employ (generalized) linear mixed models.
    Discussion: This study will provide substantial knowledge for designing effective blended interventions for OUD. Moreover, it will investigate if treatment retention and OMT-related outcomes and common mental health symptoms can be improved by adding a smartphone intervention to OMT.
    Trial registration: https://en.irct.ir/trial/53578 .
    MeSH term(s) Adult ; Humans ; Opiate Substitution Treatment/methods ; Analgesics, Opioid/therapeutic use ; Tramadol/therapeutic use ; Heroin/therapeutic use ; Opium/therapeutic use ; Iran ; Opioid-Related Disorders/drug therapy ; Opioid-Related Disorders/diagnosis ; Randomized Controlled Trials as Topic
    Chemical Substances Analgesics, Opioid ; Tramadol (39J1LGJ30J) ; Heroin (70D95007SX) ; Opium (8008-60-4)
    Language English
    Publishing date 2023-07-18
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050438-X
    ISSN 1471-244X ; 1471-244X
    ISSN (online) 1471-244X
    ISSN 1471-244X
    DOI 10.1186/s12888-023-05007-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Factors Influencing Transition to Shisheh (Methamphetamine) among Young People Who Use Drugs in Tehran: A Qualitative Study.

    Noroozi, Alireza / Malekinejad, Mohsen / Rahimi-Movaghar, Afarin

    Journal of psychoactive drugs

    2018  Volume 50, Issue 3, Page(s) 214–223

    Abstract: Background: Iran has experienced an emerging epidemic of methamphetamine use during recent years which has added to existing non-injecting and injecting opioid use in the country. This study explored factors influencing the initiation into or transition ...

    Abstract Background: Iran has experienced an emerging epidemic of methamphetamine use during recent years which has added to existing non-injecting and injecting opioid use in the country. This study explored factors influencing the initiation into or transition to methamphetamine use among young people who use drugs (PWUD).
    Methods: We conducted 42 semi-structured, in-depth interviews with young PWUD (n = 35) and health care workers (HCWs) (n = 7) between July and October 2011 in Tehran, Iran. The PWUD were purposefully recruited from different tiers of drug services and lived in geographically diverse areas of Tehran. The HCWs were substance use experts and/or service providers of treatment and harm reduction facilities. All interviews were recorded, transcribed, and coded using OpenCode 3.6 software.
    Results: The predominant factors for initiation into or transition to methamphetamine use were individual domain factors. The peer domain factors were the second most frequently stated perceived factor category for transition to methamphetamine use. Other perceived factors affecting transition to stimulant use included both family and community domains.
    Conclusion: Drug prevention programs should consider targeting certain settings, including workplaces and sports clubs, for preventative interventions. Existing opioid treatment and harm reduction services should be adjusted in response to the methamphetamine use epidemic.
    MeSH term(s) Adult ; Amphetamine-Related Disorders/epidemiology ; Central Nervous System Stimulants/administration & dosage ; Family Relations ; Female ; Harm Reduction ; Health Personnel/statistics & numerical data ; Humans ; Interviews as Topic ; Iran/epidemiology ; Male ; Methamphetamine/administration & dosage ; Opioid-Related Disorders/epidemiology ; Peer Group ; Qualitative Research ; Substance Abuse, Intravenous/epidemiology ; Young Adult
    Chemical Substances Central Nervous System Stimulants ; Methamphetamine (44RAL3456C)
    Language English
    Publishing date 2018-01-29
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 392405-1
    ISSN 2159-9777 ; 0279-1072
    ISSN (online) 2159-9777
    ISSN 0279-1072
    DOI 10.1080/02791072.2018.1425808
    Database MEDical Literature Analysis and Retrieval System OnLINE

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