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  1. Article ; Online: Psychometric and electrodermal activity data from an experimental paradigm of memory encoding with some items periodically followed by painful electric shock.

    Citro, Ally T / Norton, Caroline M / Pcola, Samantha J / Vogt, Keith M

    Data in brief

    2020  Volume 31, Page(s) 105669

    Abstract: How pain influences explicit memory is an active area of investigation, and next-day recognition was the primary outcome of this experiment. The data reported here were secondary measures of psychometrics to quantify interindividual variability between ... ...

    Abstract How pain influences explicit memory is an active area of investigation, and next-day recognition was the primary outcome of this experiment. The data reported here were secondary measures of psychometrics to quantify interindividual variability between subjects and measure electrodermal activity (EDA) changes in response to experimental stimuli. Reliable EDA responses following painful electric shocks were obtained in the Learning portion of the experiment. During next-day testing, however, no reliable EDA responses were elicited, including to previously pain-paired experimental items.
    Language English
    Publishing date 2020-05-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2786545-9
    ISSN 2352-3409 ; 2352-3409
    ISSN (online) 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2020.105669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Neutral auditory words immediately followed by painful electric shock may show reduced next-day recollection.

    Norton, Caroline M / Ibinson, James W / Pcola, Samantha J / Popov, Vencislav / Tremel, Joshua J / Reder, Lynne M / Fiez, Julie A / Vogt, Keith M

    Experimental brain research

    2022  Volume 240, Issue 11, Page(s) 2939–2951

    Abstract: In this study, we investigated the effect of experimentally delivered acute pain on memory. Twenty-five participants participated in experimental sessions on consecutive days. The first session involved a categorization task to encourage memory encoding. ...

    Abstract In this study, we investigated the effect of experimentally delivered acute pain on memory. Twenty-five participants participated in experimental sessions on consecutive days. The first session involved a categorization task to encourage memory encoding. There were two conditions, presented in randomized order, in which participants listened to a series of words, which were repeated three times. In one condition, one-third of the word items were immediately followed by a painful electrical shock. This word-shock pairing was consistent across repetition and the pain-paired items were presented unpredictably. In the other condition, all word items were not associated with pain. Response times over these repeated presentations were assessed for differences. Explicit memory was tested the following day, employing a Remember-Know assessment of word recognition, with no shocks employed. We found evidence that recollection may be reduced for pain-paired words, as the proportion of correct Remember responses (out of total correct responses) was significantly lower. There were no significant reductions in memory for non-pain items that followed painful stimulation after a period of several seconds. Consistent with the experience of pain consuming working memory resources, we theorize that painful shocks interrupt memory encoding for the immediately preceding experimental items, due to a shift in attention away from the word item.
    MeSH term(s) Humans ; Mental Recall/physiology ; Reaction Time/physiology ; Memory, Short-Term ; Attention ; Pain
    Language English
    Publishing date 2022-09-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1201-4
    ISSN 1432-1106 ; 0014-4819
    ISSN (online) 1432-1106
    ISSN 0014-4819
    DOI 10.1007/s00221-022-06467-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Neutral auditory words immediately followed by painful electric shock may show reduced next-day recollection

    Norton, Caroline M. / Ibinson, James W. / Pcola, Samantha J. / Popov, Vencislav / Tremel, Joshua J. / Reder, Lynne M. / Fiez, Julie A. / Vogt, Keith M.

    Exp Brain Res. 2022 Nov., v. 240, no. 11, p. 2939-2951

    2022  , Page(s) 2939–2951

    Abstract: In this study, we investigated the effect of experimentally delivered acute pain on memory. Twenty-five participants participated in experimental sessions on consecutive days. The first session involved a categorization task to encourage memory encoding. ...

    Abstract In this study, we investigated the effect of experimentally delivered acute pain on memory. Twenty-five participants participated in experimental sessions on consecutive days. The first session involved a categorization task to encourage memory encoding. There were two conditions, presented in randomized order, in which participants listened to a series of words, which were repeated three times. In one condition, one-third of the word items were immediately followed by a painful electrical shock. This word-shock pairing was consistent across repetition and the pain-paired items were presented unpredictably. In the other condition, all word items were not associated with pain. Response times over these repeated presentations were assessed for differences. Explicit memory was tested the following day, employing a Remember–Know assessment of word recognition, with no shocks employed. We found evidence that recollection may be reduced for pain-paired words, as the proportion of correct Remember responses (out of total correct responses) was significantly lower. There were no significant reductions in memory for non-pain items that followed painful stimulation after a period of several seconds. Consistent with the experience of pain consuming working memory resources, we theorize that painful shocks interrupt memory encoding for the immediately preceding experimental items, due to a shift in attention away from the word item.
    Keywords brain ; memory ; pain
    Language English
    Dates of publication 2022-11
    Size p. 2939-2951
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 1201-4
    ISSN 1432-1106 ; 0014-4819
    ISSN (online) 1432-1106
    ISSN 0014-4819
    DOI 10.1007/s00221-022-06467-8
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Financial Incentive, in Place of Nonclinical Time, Increases Faculty Involvement and Improves Resident Didactic Evaluation Scores in an Anesthesiology Residency Training Program.

    Adams, Douglas R / Vogt, Keith M / Norton, Caroline M / Metro, David G

    The journal of education in perioperative medicine : JEPM

    2019  Volume 21, Issue 4, Page(s) E630

    Abstract: Background: Providing clinical faculty to lead high-quality resident didactic sessions remains a challenge for academic departments that host graduate medical education training programs. In an effort to both reduce costs and to continue to recruit ... ...

    Abstract Background: Providing clinical faculty to lead high-quality resident didactic sessions remains a challenge for academic departments that host graduate medical education training programs. In an effort to both reduce costs and to continue to recruit faculty to give lectures, our department began to incentivize clinicians with a $500 stipend in place of a nonclinical day to present didactics. Our hypothesis is that with financial incentive, more attendings would present didactics and the quality would improve.
    Methods: Residents routinely evaluate all didactic sessions using a Likert scale of 1 to 5. Residents also answer yes or no to indicate whether the presenter should return. We compared academic year (AY) 2016, in which faculty were incentivized with nonclinical time, with AY 2017 and AY 2018, in which incentive came in the form of a $500 stipend. For each, the mean Likert score and percentage of positive responses for lecturer returning were calculated. A 1-way ANOVA and post hoc t tests were performed to determine significant changes.
    Results: Comparing AY 2016 (before the incentive switch) with AY 2017 and AY 2018, there was more faculty involvement in resident didactic after implementing the financial incentive. The quality of lectures also improved after the incentive switch, according to resident evaluations. There were higher overall Likert scores in AY 2018 and a higher percentage of positive responses to the question of whether presenters should return in AY 2017 and AY 2018, compared with AY 2016.
    Conclusions: After implementation of a financial incentive in place of nonclinical time, more faculty became involved in lectures and overall lecture quality improved as measured by resident evaluations.
    Language English
    Publishing date 2019-10-01
    Publishing country United States
    Document type Journal Article
    ISSN 2333-0406
    ISSN 2333-0406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reporting of Patient Experience Data on Health Systems' Websites and Commercial Physician-Rating Websites: Mixed-Methods Analysis.

    Lagu, Tara / Norton, Caroline M / Russo, Lindsey M / Priya, Aruna / Goff, Sarah L / Lindenauer, Peter K

    Journal of medical Internet research

    2019  Volume 21, Issue 3, Page(s) e12007

    Abstract: Background: Some hospitals' and health systems' websites report physician-level ratings and comments drawn from the Consumer Assessment of Healthcare Providers and Systems surveys.: Objective: The aim was to examine the prevalence and content of ... ...

    Abstract Background: Some hospitals' and health systems' websites report physician-level ratings and comments drawn from the Consumer Assessment of Healthcare Providers and Systems surveys.
    Objective: The aim was to examine the prevalence and content of health system websites reporting these data and compare narratives from these sites to narratives from commercial physician-rating sites.
    Methods: We identified health system websites active between June 1 and 30, 2016, that posted clinician reviews. For 140 randomly selected clinicians, we extracted the number of star ratings and narrative comments. We conducted a qualitative analysis of a random sample of these physicians' narrative reviews and compared these to a random sample of reviews from commercial physician-rating websites. We described composite quantitative scores for sampled physicians and compared the frequency of themes between reviews drawn from health systems' and commercial physician-rating websites.
    Results: We identified 42 health systems that published composite star ratings (42/42, 100%) or narratives (33/42, 79%). Most (27/42, 64%) stated that they excluded narratives deemed offensive. Of 140 clinicians, the majority had composite scores listed (star ratings: 122/140, 87.1%; narrative reviews: 114/140, 81.4%), with medians of 110 star ratings (IQR 42-175) and 25.5 (IQR 13-48) narratives. The rating median was 4.8 (IQR 4.7-4.9) out of five stars, and no clinician had a score less than 4.2. Compared to commercial physician-rating websites, we found significantly fewer negative comments on health system websites (35.5%, 76/214 vs 12.8%, 72/561, respectively; P<.001).
    Conclusions: The lack of variation in star ratings on health system sites may make it difficult to differentiate between clinicians. Most health systems report that they remove offensive comments, and we notably found fewer negative comments on health system websites compared to commercial physician-rating sites.
    MeSH term(s) Female ; Humans ; Internet ; Male ; Patient Satisfaction/statistics & numerical data ; Physicians ; Research Design ; Social Networking ; Surveys and Questionnaires
    Language English
    Publishing date 2019-03-27
    Publishing country Canada
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/12007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Memory for non-painful auditory items is influenced by whether they are experienced in a context involving painful electrical stimulation.

    Vogt, Keith M / Norton, Caroline M / Speer, Lauren E / Tremel, Joshua J / Ibinson, James W / Reder, Lynne M / Fiez, Julie A

    Experimental brain research

    2019  Volume 237, Issue 7, Page(s) 1615–1627

    Abstract: In this study, we sought to examine the effect of experimentally induced somatic pain on memory. Subjects heard a series of words and made categorization decisions in two different conditions. One condition included painful shocks administered just after ...

    Abstract In this study, we sought to examine the effect of experimentally induced somatic pain on memory. Subjects heard a series of words and made categorization decisions in two different conditions. One condition included painful shocks administered just after presentation of some of the words; the other condition involved no shocks. For the condition that included painful stimulations, every other word was followed by a shock, and subjects were informed to expect this pattern. Word lists were repeated three times within each condition in randomized order, with different category judgments but consistent pain-word pairings. After a brief delay, recognition memory was assessed. Non-pain words from the pain condition were less strongly encoded than non-pain words from the completely pain-free condition. Recognition of pain-paired words was not significantly different than either subgroup of non-pain words. An important accompanying finding is that response times to repeated experimental items were slower for non-pain words from the pain condition, compared to non-pain words from the completely pain-free condition. This demonstrates that the effect of pain on memory may generalize to non-pain items experienced in the same experimental context.
    MeSH term(s) Acoustic Stimulation/adverse effects ; Acoustic Stimulation/methods ; Adult ; Electric Stimulation/adverse effects ; Female ; Humans ; Male ; Memory/physiology ; Mental Recall/physiology ; Pain/physiopathology ; Pain/psychology ; Random Allocation ; Reaction Time/physiology ; Young Adult
    Language English
    Publishing date 2019-04-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1201-4
    ISSN 1432-1106 ; 0014-4819
    ISSN (online) 1432-1106
    ISSN 0014-4819
    DOI 10.1007/s00221-019-05534-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain.

    Vogt, Keith M / Ibinson, James W / Smith, C Tyler / Citro, Ally T / Norton, Caroline M / Karim, Helmet T / Popov, Vencislav / Mahajan, Aman / Aizenstein, Howard J / Reder, Lynne M / Fiez, Julie A

    Anesthesiology

    2021  Volume 135, Issue 1, Page(s) 69–82

    MeSH term(s) Adolescent ; Adult ; Analgesics/pharmacology ; Anesthetics, Intravenous/pharmacology ; Brain/diagnostic imaging ; Brain/drug effects ; Cross-Over Studies ; Fear/drug effects ; Female ; Humans ; Ketamine/pharmacology ; Magnetic Resonance Imaging/methods ; Male ; Memory/drug effects ; Midazolam/pharmacology ; Neural Pathways/drug effects ; Pain/drug therapy ; Single-Blind Method ; Young Adult
    Chemical Substances Analgesics ; Anesthetics, Intravenous ; Ketamine (690G0D6V8H) ; Midazolam (R60L0SM5BC)
    Language English
    Publishing date 2021-04-19
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000003774
    Database MEDical Literature Analysis and Retrieval System OnLINE

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