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  1. Article: The Eyeball Test.

    Nossaman, Bobby D

    The Ochsner journal

    2023  Volume 23, Issue 2, Page(s) 100–103

    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Editorial
    ISSN 1524-5012
    ISSN 1524-5012
    DOI 10.31486/toj.23.5035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Rate of Intraoperative Crystalloid Administration During Thoracic Surgery Is Causal in Reducing Postoperative Hospital Length of Stay.

    Smith, Morgan T / Peairs, Ashley D / Nossaman, Bobby D

    The Ochsner journal

    2023  Volume 23, Issue 2, Page(s) 106–119

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Journal Article
    ISSN 1524-5012
    ISSN 1524-5012
    DOI 10.31486/toj.22.0113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Transfusion-Related Acute Lung Injury (TRALI): Report of 2 Cases and a Review of The Literature.

    Nossaman, Bobby D

    The Ochsner journal

    2011  Volume 8, Issue 1, Page(s) 32–38

    Abstract: Transfusion of allogeneic blood products is given for correction of coagulation deficits and for the improvement in oxygen-carrying capacity or delivery. Blood transfusion has become safer following the advancement in blood testing using state-of-the-art ...

    Abstract Transfusion of allogeneic blood products is given for correction of coagulation deficits and for the improvement in oxygen-carrying capacity or delivery. Blood transfusion has become safer following the advancement in blood testing using state-of-the-art viral assays; however, there continues to exist a variety of noninfectious transfusion risks that still remain and that cannot be entirely eliminated. Research is now directed towards understanding these lesser-known, but serious transfusion-related complications. This purpose of this review is to discuss a serious noninfectious cause of acute lung injury, transfusion-related acute lung injury (TRALI), which occurred in 2 recent cases in the intensive care unit, and to review the current literature of this syndrome.
    Keywords covid19
    Language English
    Publishing date 2011-04-25
    Publishing country United States
    Document type Journal Article
    ISSN 1524-5012
    ISSN 1524-5012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Airway risk factors for the Miller laryngoscope blade.

    Landry, William B / Nossaman, Bobby D

    Journal of clinical anesthesia

    2016  Volume 33, Page(s) 62–67

    Abstract: Study objective: The purpose of this study was to analyze previously reported airway risk factors in the performance of Miller laryngoscopy and orotracheal intubation.: Design: Prospective, observational study.: Setting: Operating rooms.: ... ...

    Abstract Study objective: The purpose of this study was to analyze previously reported airway risk factors in the performance of Miller laryngoscopy and orotracheal intubation.
    Design: Prospective, observational study.
    Setting: Operating rooms.
    Patients: A total of 978 American Society of Anesthesiologists I-III adults requiring general orotracheal anesthesia for elective surgery.
    Interventions: None.
    Measurements: Nine previously reported airway risk factors used in predicting difficult laryngoscopy, modified McCormack-Lehane views observed during initial unaided Miller blade laryngoscopy, and number of attempts or need for alternate airway tools to facilitate orotracheal intubation.
    Main results: Orotracheal intubation occurred in 941 of 978 (96.2%) patients with the Miller blade, although 8 patients required 3 attempts, with the remaining 37 patients requiring alternate airway tools. There were no failed orotracheal intubations. Multivariable analysis revealed that modified Mallampati class, thyromental distance, and ability to prognath were associated with progressively inferior modified Cormack-Lehane views, whereas modified Mallampati class, height, and head and neck extension were associated with progressive difficulty with orotracheal intubation.
    Conclusions: The Miller blade is highly successful in the performance of direct laryngoscopy for orotracheal intubation. These findings suggest that different sets of airway risk factors affect the process of laryngoscopy and orotracheal intubation.
    MeSH term(s) Adolescent ; Adult ; Aged ; Anesthesia, General/methods ; Equipment Design ; Female ; Humans ; Intubation, Intratracheal/instrumentation ; Intubation, Intratracheal/methods ; Laryngoscopes ; Laryngoscopy/instrumentation ; Laryngoscopy/methods ; Male ; Middle Aged ; Prospective Studies ; ROC Curve ; Risk Factors ; Treatment Failure ; Young Adult
    Language English
    Publishing date 2016-09
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2016.01.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Preoperative Administration of Hycet Elixir Reduces Hospital Length of Stay After Pediatric Outpatient Adeno/Tonsillectomy.

    Salcedo, Luis F / LeBlanc, Brooke L / Martin, Sarah M / Nossaman, Bobby D

    The Ochsner journal

    2021  Volume 21, Issue 3, Page(s) 240–244

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-07-06
    Publishing country United States
    Document type Journal Article
    ISSN 1524-5012
    ISSN 1524-5012
    DOI 10.31486/toj.20.0101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Modified Early Warning Score as a Predictive Tool During Unplanned Surgical Intensive Care Unit Admission.

    Kumar, Annandita / Ghabra, Hussam / Winterbottom, Fiona / Townsend, Michael / Boysen, Philip / Nossaman, Bobby D

    The Ochsner journal

    2020  Volume 20, Issue 2, Page(s) 176–181

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2020-06-29
    Publishing country United States
    Document type Journal Article
    ISSN 1524-5012
    ISSN 1524-5012
    DOI 10.31486/toj.19.0057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Effect of the IPACK Block on Pain After Primary TKA: A Double-Blinded, Prospective, Randomized Trial.

    Patterson, Matthew E / Vitter, Jillian / Bland, Kim / Nossaman, Bobby D / Thomas, Leslie C / Chimento, George F

    The Journal of arthroplasty

    2020  Volume 35, Issue 6S, Page(s) S173–S177

    Abstract: Background: The purpose of this study was to determine if infiltration of local anesthetic between the interspace between the popliteal artery and capsule of the knee (IPACK) provides benefit in total knee arthroplasty.: Methods: Patients were ... ...

    Abstract Background: The purpose of this study was to determine if infiltration of local anesthetic between the interspace between the popliteal artery and capsule of the knee (IPACK) provides benefit in total knee arthroplasty.
    Methods: Patients were randomized into continuous adductor canal block with IPACK block or continuous adductor canal block with sham subcutaneous saline injection. Only the anesthesiologist performing the block was aware of randomization status. After surgery, a blinded assessor recorded opioid consumption, pain scores, and gait distance.
    Results: There were 35 patients in the IPACK group and 34 in the NO IPACK group. There was no difference demographically between the groups. In the postanesthesia care unit (PACU), the average (P = .0122) and worst (P = .0168) pain scores at rest were statistically lower in the IPACK group. There was no difference in the pain scores during physical therapy (P = .2080). There was no difference in opioid consumption in the PACU (P = .7928), or at 24 hours (P = .7456). There was no difference in pain scores on POD 1 in the AM (P = .4597) or PM (P = .6273), or in the walking distance (P = .5197). There was also no difference in length of stay in the PACU (P = .9426) or hospital (P = .2141).
    Conclusion: The IPACK group had lower pain scores at rest in the PACU, but this is likely not clinically significant. The routine use of the IPACK is not supported by the results of this study. There may be indications for the use of the IPACK block as a rescue block or in patients who have contraindications to our standard multimodal treatment regimen or in patients with chronic pain or opioid dependence.
    MeSH term(s) Analgesics, Opioid ; Anesthetics, Local ; Arthroplasty, Replacement, Knee/adverse effects ; Humans ; Nerve Block ; Pain, Postoperative/epidemiology ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Prospective Studies ; Treatment Outcome
    Chemical Substances Analgesics, Opioid ; Anesthetics, Local
    Language English
    Publishing date 2020-01-15
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2020.01.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Stimulators of soluble guanylyl cyclase: future clinical indications.

    Nossaman, Bobby D / Kadowitz, Philip J

    The Ochsner journal

    2013  Volume 13, Issue 1, Page(s) 147–156

    Abstract: Background: Soluble guanylyl cyclase (sGC) is expressed in mammalian cytoplasm and catalyzes the synthesis of the second messenger guanosine 3',5'-monophosphate (cGMP) involved in important physiological functions such as relaxation of vascular smooth ... ...

    Abstract Background: Soluble guanylyl cyclase (sGC) is expressed in mammalian cytoplasm and catalyzes the synthesis of the second messenger guanosine 3',5'-monophosphate (cGMP) involved in important physiological functions such as relaxation of vascular smooth muscle, inhibition of platelet aggregation, modulation of inflammation, and control of vascular permeability. sGC is the intracellular receptor for nitric oxide (NO) and the active moiety in traditional organic nitrate therapy, recently as an inhalant in the intensive care unit and experimentally in improving microcirculatory flow in shock. However, dysfunction of the heme moiety on sGC occurs in a number of cardiovascular diseases, which reduces NO effectiveness.
    Methods: In this review, we examine animal studies and early clinical trials on agents that can directly stimulate sGC and may have future clinical application in cardiovascular disease and in perioperative care.
    Conclusions: Animal and early clinical studies have shown that sGC stimulator agents have great promise for treating cardiopulmonary disorders and may also have a role in modulating the inflammatory response observed in perioperative care.
    Language English
    Publishing date 2013-03-26
    Publishing country United States
    Document type Journal Article
    ISSN 1524-5012
    ISSN 1524-5012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Dyed but not dead.

    Haque, Shireen H / Nossaman, Bobby D

    The Ochsner journal

    2012  Volume 12, Issue 2, Page(s) 135–140

    Abstract: The use of vital blue dyes in sentinel lymph node mapping and biopsy is gaining popularity in the surgical management of cancer. However, intraoperative use of these dyes has associated risks for the patient. This case report and review of the literature ...

    Abstract The use of vital blue dyes in sentinel lymph node mapping and biopsy is gaining popularity in the surgical management of cancer. However, intraoperative use of these dyes has associated risks for the patient. This case report and review of the literature present current medical knowledge about one of the vital blue dyes, isosulfan blue, and the associated clinical risks of this dye when used in the perioperative management of patients who undergo sentinel lymph node mapping and biopsy.
    Language English
    Publishing date 2012-06-13
    Publishing country United States
    Document type Case Reports
    ISSN 1524-5012
    ISSN 1524-5012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Duration of Nil Per Os is causal in hospital length of stay following laparoscopic bariatric surgery.

    Nossaman, Vaughn E / Richardson, William S / Wooldridge, James B / Nossaman, Bobby D

    Surgical endoscopy

    2017  Volume 31, Issue 4, Page(s) 1901–1905

    Abstract: Introduction: A recent bariatric surgical study demonstrated an inverse relationship of intraoperative hydration with the incidence of extended hospital length of stay (ehLOS: >1 postoperative hospital day). In that study, a post hoc analysis of the ... ...

    Abstract Introduction: A recent bariatric surgical study demonstrated an inverse relationship of intraoperative hydration with the incidence of extended hospital length of stay (ehLOS: >1 postoperative hospital day). In that study, a post hoc analysis of the preoperative duration of Nil Per Os (NPO) past midnight revealed a significant dose-response association on the incidence of ehLOS, with the lowest incidence (10-12 %) predicted within the 2-5-h NPO interval. As NPO is associated with a state of compensatory dehydration, the objectives of this study were to prospectively examine the role of decreasing preoperative NPO intervals on the incidence of ehLOS in a similar bariatric surgical population and to establish causality of this association.
    Methods: Following IRB approval, 168 bariatric surgeries were analyzed following institution of a revised oral water ad libitum policy until 2 h prior to surgery on the incidence of ehLOS. The role of duration of NPO on the incidence of ehLOS was assessed by logistic fit graphs and misclassification rates on the two groups. A statistical process control chart monitored the efficacy of the revised NPO guidelines.
    Results: There were statistically significant, but not clinical, differences in the incidences of histories of anemia, gastroesophageal reflux disease, previous percutaneous cardiac intervention/percutaneous transluminal coronary artery angioplasty, or preoperative albumin levels between the two groups. There were no perioperative pulmonary aspirations of gastric contents in either group. Following reduction of the oral hydration interval to ≥2 h, a 13-15 % incidence of ehLOS was observed within the 2-5-h NPO interval with similar misclassification rates observed between the two groups.
    Conclusions: Allowing bariatric patients access to ad libitum water for up to 2 h prior to surgery decreased the incidence of ehLOS. Comparison of the dose-response curves within the 2-5-h NPO intervals before and after introduction of the revised NPO guidelines was similar and confirms causality.
    MeSH term(s) Adult ; Bariatric Surgery ; Drinking ; Female ; Humans ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Outcome Assessment (Health Care) ; Preoperative Care/adverse effects ; Preoperative Care/methods ; Prospective Studies ; Time Factors
    Language English
    Publishing date 2017-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-016-5191-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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